Research Topics
Species | S A BinghamSummaryAffiliation: University of Cambridge Country: UK Publications
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Detail Information
Publications
High-meat diets and cancer riskS A Bingham
Medical Research Council, Dunn Nutrition Unit, Cambridge, UK
Proc Nutr Soc 58:243-8. 1999..Current Department of Health (1998) recommendations are that meat consumption should not rise, and that consumers at the top end of the distribution should consider a reduction in intakes...
Using biochemical markers to assess the validity of prospective dietary assessment methods and the effect of energy adjustmentS A Bingham
Medical Research Council Dunn Clinical Nutrition Centre, Cambridge, United Kingdom
Am J Clin Nutr 65:1130S-1137S. 1997....
Phyto-oestrogens: where are we now?S A Bingham
MRC Dunn Clinical Nutrition Centre, Cambridge, UK
Br J Nutr 79:393-406. 1998..This problem may prove to be a major dilemma for regulatory authorities, clinicians and others wishing to advise the general public on whether these compounds really do have the health benefits attributed to them...
Nutritional methods in the European Prospective Investigation of Cancer in NorfolkS A Bingham
EPIC, Institute of Public Health and Strangeways Research Laboratories, Worts Causeway, Cambridge CB1 4RN, UK
Public Health Nutr 4:847-58. 2001..To describe methods and dietary habits of a large population cohort...
Use of biological markers to validate self-reported dietary intake in a random sample of the European Prospective Investigation into Cancer United Kingdom Norfolk cohortN M McKeown
Medical Research Council, Dunn Human Nutrition Unit, Cambridge, United Kingdom
Am J Clin Nutr 74:188-96. 2001..However, with respect to plasma ascorbic acid, both the FFQ and 7-d food diary provided a similar ranking of subjects according to vitamin C intake...
Sense of coherence, lifestyle choices and mortalityN W J Wainwright
Strangeways Research Laboratory, Worts Causeway, Cambridge CB1 8RN, UK
J Epidemiol Community Health 62:829-31. 2008..Based on data from the European Prospective Investigation into Cancer, Norfolk (EPIC-Norfolk) study, we have previously shown a strong sense of coherence (SOC) to be associated with a reduced rate of all-cause mortality...
Intakes and sources of soya foods and isoflavones in a UK population cohort study (EPIC-Norfolk)A A Mulligan
EPIC, Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Worts Causeway, Cambridge, UK
Eur J Clin Nutr 61:248-54. 2007..However, there are little available data on the food sources or distribution of intake in the UK diet...
Apolipoprotein E genotype modulates the effect of black tea drinking on blood lipids and blood coagulation factors: a pilot studyA Loktionov
Medical Research Council, Dunn Clinical Nutrition Centre, Cambridge, UK
Br J Nutr 79:133-9. 1998..Dietary intervention may be particularly effective in population groups with certain genetic characteristics...
Factor VII, blood lipids and fat intake: gene-nutrient interaction and risk of coronary heart disease with the factor VII R353Q polymorphismR Bowman
MRC Dunn Human Nutrition Unit, Cambridge, UK
Eur J Clin Nutr 63:771-7. 2009..The relation between dietary fat, blood lipids, plasma factor VII coagulant activity (FVIIc) and risk of coronary heart disease (CHD) according to the R353Q polymorphism in the factor VII gene was assessed...
Physical health-related quality of life predicts stroke in the EPIC-NorfolkP K Myint
Department of Public Health and Primary Care, University of Cambridge, Cambridge, UK
Neurology 69:2243-8. 2007..To examine the relationship between Short Form (SF)-36 physical functional health-related quality of life and incident stroke...
Plant polysaccharides, meat and colorectal cancerS A Bingham
EPIC Norfolk, Strangeways Research Laboratory, Cambridge, UK
IARC Sci Publ 156:349-52. 2002
Urinary sugars biomarker relates better to extrinsic than to intrinsic sugars intake in a metabolic study with volunteers consuming their normal dietN Tasevska
MRC Dunn Human Nutrition Unit, Wellcome Trust MRC Building, Cambridge, UK
Eur J Clin Nutr 63:653-9. 2009..To further characterize the use of this biomarker, we investigated whether urinary sugars correlated better to extrinsic compared to intrinsic sugars in the diet...
Psychological distress, major depressive disorder, and risk of strokeP G Surtees
Strangeways Research Laboratory, University of Cambridge, Department of Public Health and Primary Care, Cambridge, CB1 8RN, UK
Neurology 70:788-94. 2008..We investigated this association based upon a large population-based prospective cohort study...
Twenty-four-hour urinary thiamine as a biomarker for the assessment of thiamine intakeN Tasevska
MRC Dunn Human Nutrition Unit, University of Cambridge, Cambridge, UK
Eur J Clin Nutr 62:1139-47. 2008..To investigate 24-h urinary thiamine as a potential biomarker for thiamine intake for use in validation studies to assess the validity of dietary intake data collected by self-reporting dietary methods...
Dietary antioxidants and asthma in adultsB D Patel
Department of Public Health and Primary Care, Institute of Public Health, Cambridge, UK
Thorax 61:388-93. 2006..These findings suggest that diet may be a potentially modifiable risk factor for the development of asthma...
Effect of a pilot community intervention on fruit and vegetable intakes: use of FACET (Five-a-day Community Evaluation Tool)P A L Ashfield-Watt
EPIC University of Cambridge, Institute of Public Health and Strangeways Research Laboratories, Cambridge, UK
Public Health Nutr 10:671-80. 2007..The effectiveness of the programme and the use of a brief tool for evaluating community interventions are reported here...
Is 'five-a-day' an effective way of increasing fruit and vegetable intakes?P A L Ashfield-Watt
EPIC, University of Cambridge, Institute of Public Health and Strangeways Research Laboratories, Worts Causeway, Cambridge CB1 8RN, UK
Public Health Nutr 7:257-61. 2004..To assess whether the amount of fruits and vegetables consumed depends on the serving size or on how often fruits and vegetables are eaten...
The CAFE computer program for nutritional analysis of the EPIC-Norfolk food frequency questionnaire and identification of extreme nutrient valuesA A Welch
Department of Public Health and Primary Care, University of Cambridge, Strangeways Site, Wort s Causeway, Cambridge, UK
J Hum Nutr Diet 18:99-116. 2005..Extreme nutrient values and derivation of cut-points for data exclusion are also discussed...
Apolipoprotein E and methylenetetrahydrofolate reductase genetic polymorphisms in relation to other risk factors for cardiovascular disease in UK Caucasians and Black South AfricansA Loktionov
Dunn Clinical Nutrition Centre, Cambridge, UK
Atherosclerosis 145:125-35. 1999..The exceptionally low frequency of MTHFR mutant homozygotes in this population suggests that this polymorphism should not be regarded as an important CHD risk factor among Black South Africans...
Respiratory function and self-reported functional health: EPIC-Norfolk population studyP K Myint
Room 311, Strangeways Research Laboratory, Wort s Causeway, Cambridge, CB1 8RN, UK
Eur Respir J 26:494-502. 2005..00; 95% CI 0.82-1.22). In conclusion, forced expiratory volume in one second independently predicts self perceived physical well being in a general population across the whole normal distribution of respiratory function...
The effect of haem in red and processed meat on the endogenous formation of N-nitroso compounds in the upper gastrointestinal tractJ C Lunn
MRC Dunn Human Nutrition Unit, MRC Wellcome Trust Building, Cambridge, CB2 2XY, UK
Carcinogenesis 28:685-90. 2007..8 but not in the absence of nitrosated haemoglobin. These findings demonstrate that haem may facilitate the formation of NOC in the absence of colonic flora in the upper human gastrointestinal tract...
Starch intake and colorectal cancer risk: an international comparisonA Cassidy
Medical Research Council, Dunn Clinical Nutrition Centre, Cambridge, UK
Br J Cancer 69:937-42. 1994..Measures of both starch and NSPs need to be included in future epidemiological studies of diet and bowel cancer...
Urinary sucrose and fructose as biomarkers of sugar consumption: comparison of normal weight and obese volunteersA M C P Joosen
MRC Dunn Human Nutrition Unit, Wellcome Trust MRC Building, Cambridge, UK
Int J Obes (Lond) 32:1736-40. 2008..In conclusion, BMI does not affect the validity of sucrose and fructose excretions in 24-h urine collections used as biomarkers to estimate total sugar consumption...
Habitual fish consumption and glycated haemoglobin: the EPIC-Norfolk studyA-H Harding
Department of Public Health and Primary Care, Institute of Public Health, University of Cambridge, Cambridge, UK
Eur J Clin Nutr 58:277-84. 2004..In men, there was no evidence that HbA(1c) level was associated with fish consumption. CONCLUSIONS: The study found no evidence of an association between fish consumption and HbA(1c) after taking other lifestyle factors into account...
Daidzein and genistein content of cerealsJ Liggins
Medical Research Council Dunn Human Nutrition Unit, Hills Road, Cambridge, UK
Eur J Clin Nutr 56:961-6. 2002..SPONSORSHIP: This work was supported by the United Kingdom Medical Research Council, Ministry of Agriculture Fisheries and Food (contract FS2034) and the United States of America Army (contract DAMD 17-97-1-7028)...
Red meat and colorectal cancer risk: the effect of dietary iron and haem on endogenous N-nitrosationA J Cross
MRC Dunn Human Nutrition Unit, Hills Rd, Cambridge, CB2 2XY, UK
IARC Sci Publ 156:205-6. 2002
Childhood smoking is an independent risk factor for obstructive airways disease in womenB D Patel
Department of Public Health and Primary Care, Institute of Public Health, University Forvie Site, Robinson Way, Cambridge CB2 2SR, UK
Thorax 59:682-6. 2004..To assess whether starting to smoke in childhood increases the risk of obstructive airways disease (OAD) in adult life...
Gene-nutrient interactions: dietary behaviour associated with high coronary heart disease risk particularly affects serum LDL cholesterol in apolipoprotein E epsilon4-carrying free-living individualsA Loktionov
Dunn Human Nutrition Unit, Wellcome Trust MRC, Cambridge
Br J Nutr 84:885-90. 2000....
Dietary meat, endogenous nitrosation and colorectal cancerG G C Kuhnle
MRC Dunn Human Nutrition Unit, Wellcome Trust MRC Building, Hills Road, Cambridge CB2 0XY, U K
Biochem Soc Trans 35:1355-7. 2007..Nitrosyl haem and other nitroso compounds can then form under the alkaline and reductive conditions of the small and large bowel...
Differential leucocyte count and the risk of future coronary artery disease in healthy men and women: the EPIC-Norfolk Prospective Population StudyJ S Rana
Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands
J Intern Med 262:678-89. 2007..There is paucity of data on the differential leucocyte count and its relationship with the risk of CHD and CVD...
Gender-stratified analysis of DLG5 R30Q in 4707 patients with Crohn disease and 4973 controls from 12 Caucasian cohortsB L Browning
J Med Genet 45:36-42. 2008..010, OR = 0.86, 95% CI 0.76 to 0.97), but not in men. CONCLUSION: DLG5 30Q is associated with a small reduction in risk of CD in women...
Daidzein and genistein intakes in England (the EPIC Norfolk cohort)A A Mulligan
Department of Public Health and Primary Care, University of Cambridge, UK
IARC Sci Publ 156:369-70. 2002
Glutathione-S-transferase gene polymorphisms in colorectal cancer patients: interaction between GSTM1 and GSTM3 allele variants as a risk-modulating factorA Loktionov
MRC Dunn Human Nutrition Unit, Cambridge CB2 2XY, UK
Carcinogenesis 22:1053-60. 2001....
Malondialdehyde-DNA adducts in relation to diet and disease risk--a brief overview of recent resultsD E G Shuker
Department of Chemistry, Open University, Walton Hall, Milton Keynes MK7 6AA, UK
IARC Sci Publ 156:475-80. 2002
Tissue factor serum levels and the risk of future coronary artery disease in apparently healthy men and women: the EPIC-Norfolk prospective population studyT T Keller
Department of Vascular Medicine, Academic Medical Center, Amsterdam, The Netherlands
J Thromb Haemost 4:2391-6. 2006..High levels of circulating TF are found in patients with acute atherothrombotic events. Whether high serum TF levels predict risk of future CAD independent of known risk factors remains unknown...
