Monica Bettencourt-Dias

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi Heterogeneous proliferative potential in regenerative adult newt cardiomyocytes
    Monica Bettencourt-Dias
    Department of Biochemistry, University College London, London WC1E 6BT, UK
    J Cell Sci 116:4001-9. 2003
  2. ncbi Genome-wide survey of protein kinases required for cell cycle progression
    M Bettencourt-Dias
    Cancer Research UK Cell Cycle Genetics Research Group, University of Cambridge, Department of Genetics, Downing Street, Cambridge CB2 3EH, UK
    Nature 432:980-7. 2004
  3. ncbi SAK/PLK4 is required for centriole duplication and flagella development
    M Bettencourt-Dias
    Cancer Research UK Cell Cycle Genetics Research Group, Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom
    Curr Biol 15:2199-207. 2005
  4. doi Asterless is a scaffold for the onset of centriole assembly
    Nikola S Dzhindzhev
    Cancer Research UK Cell Cycle Genetics Group, University of Cambridge, Department of Genetics, Downing Street, Cambridge CB2 3EH, UK
    Nature 467:714-8. 2010
  5. ncbi DSAS-6 organizes a tube-like centriole precursor, and its absence suggests modularity in centriole assembly
    Ana Rodrigues-Martins
    Cancer Research UK Cell Cycle Genetics Research Group, Department of Genetics, University of Cambridge, Cambridge, UK
    Curr Biol 17:1465-72. 2007
  6. ncbi From centriole biogenesis to cellular function: centrioles are essential for cell division at critical developmental stages
    Ana Rodrigues-Martins
    Instituto Gulbenkian de Ciencia, Cell Cycle Regulation Lab, Oeiras, Portugal
    Cell Cycle 7:11-6. 2008

Collaborators

Detail Information

Publications6

  1. ncbi Heterogeneous proliferative potential in regenerative adult newt cardiomyocytes
    Monica Bettencourt-Dias
    Department of Biochemistry, University College London, London WC1E 6BT, UK
    J Cell Sci 116:4001-9. 2003
    ..Understanding the nature of this block and why it arises in some but not other newt cardiomyocytes may lead to an augmentation of the regenerative potential in the mammalian heart...
  2. ncbi Genome-wide survey of protein kinases required for cell cycle progression
    M Bettencourt-Dias
    Cancer Research UK Cell Cycle Genetics Research Group, University of Cambridge, Department of Genetics, Downing Street, Cambridge CB2 3EH, UK
    Nature 432:980-7. 2004
    ..The survey reveals the inter-digitation of systems that monitor cellular physiology, cell size, cellular stress and signalling processes with the basic cell cycle regulatory machinery...
  3. ncbi SAK/PLK4 is required for centriole duplication and flagella development
    M Bettencourt-Dias
    Cancer Research UK Cell Cycle Genetics Research Group, Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom
    Curr Biol 15:2199-207. 2005
    ..SAK-/- mice die during embryogenesis, whereas SAK+/- mice develop liver and lung tumors and SAK+/- MEFs show mitotic abnormalities. However, the mechanism underlying these phenotypes is still not known...
  4. doi Asterless is a scaffold for the onset of centriole assembly
    Nikola S Dzhindzhev
    Cancer Research UK Cell Cycle Genetics Group, University of Cambridge, Department of Genetics, Downing Street, Cambridge CB2 3EH, UK
    Nature 467:714-8. 2010
    ..Our findings identify independent functions for Asl as a scaffold for Plk4 and Sas-4 that facilitates self-assembly and duplication of the centriole and organization of pericentriolar material...
  5. ncbi DSAS-6 organizes a tube-like centriole precursor, and its absence suggests modularity in centriole assembly
    Ana Rodrigues-Martins
    Cancer Research UK Cell Cycle Genetics Research Group, Department of Genetics, University of Cambridge, Cambridge, UK
    Curr Biol 17:1465-72. 2007
    ..We propose that the tube is built from nine subunits fitting together laterally and longitudinally in a modular and sequential fashion, like pieces of a layered "hollow" cake...
  6. ncbi From centriole biogenesis to cellular function: centrioles are essential for cell division at critical developmental stages
    Ana Rodrigues-Martins
    Instituto Gulbenkian de Ciencia, Cell Cycle Regulation Lab, Oeiras, Portugal
    Cell Cycle 7:11-6. 2008
    ..This heterogeneity should be taken into account both in reaching an understanding of spindle function and when designing drugs that target cell division...