Affiliation: University College London
- Bio-ecological control of chronic liver disease and encephalopathyStig Bengmark
Lund University, Lund, Sweden
Metab Brain Dis 24:223-36. 2009..Subsequent studies with other lactic acid bacteria seem to demonstrate suppression of inflammation and in one study also evidence of clinical improvement...
- Impact of nutrition on ageing and diseaseStig Bengmark
Lund University, Lund, Sweden
Curr Opin Clin Nutr Metab Care 9:2-7. 2006....
- [Diet of our time behind inflammation and disease development. Heating of food produces dysfunctional proteins which accumulates in the body]Stig Bengmark
University College, London University
Lakartidningen 104:3873-7. 2007
- Integrative medicine and human health - the role of pre-, pro- and synbioticsStig Bengmark
Division of Surgery and Interventional Science, University College London, 4th Floor, 74 Huntley Street, London, WC1E 6AU, UK
Clin Transl Med 1:6. 2012....
- The role of hepatic fat accumulation in pathogenesis of non-alcoholic fatty liver disease (NAFLD)Qing Liu
Deaprtment of Endocrinology, Tenth People s Hospital, Tongji University, Shanghai 200072, China
Lipids Health Dis 9:42. 2010..Special emphasis is given suggestions of new targets treatment and prevention of nonalcoholic fatty liver disease...
- Nutrigenomics therapy of hepatisis C virus induced-hepatosteatosisQing Liu
Department of Endocrinology, Tenth People s Hospital, Tongji University, Shanghai 200072, China
BMC Gastroenterol 10:49. 2010....
- Bio-ecological control of acute pancreatitis: the role of enteral nutrition, pro and synbioticsStig Bengmark
Institute of Hepatology, University College London Medical School, London, UK
Curr Opin Clin Nutr Metab Care 8:557-61. 2005..Clearly, the main role of enteral nutrition is to boost the immune system, and not, at least initially, to provide calories. Whereas enteral nutrition improves, parenteral nutrition reduces immune functions...
- Bioecologic control of the gastrointestinal tract: the role of flora and supplemented probiotics and synbioticsStig Bengmark
Departments of Hepatology and Surgery, Institute of Hepatology, University College, London Medical School, 69 75 Chenies Mews, London, WC1E 6HX, United Kingdom
Gastroenterol Clin North Am 34:413-36, viii. 2005
- Prebiotics and synbiotics in clinical medicineStig Bengmark
Departments of Hepatology and Surgery, University College of London UCL, London Medical School, 69 75 Chenies Mews, London WC1E 6HX, UK
Nutr Clin Pract 20:244-61. 2005..Some edge-cutting effects from using multistrain and multifiber compositions are reported both from animal and controlled clinical studies...
- Synbiotics and the mucosal barrier in critically ill patientsStig Bengmark
Institute of Hepatology, University College, London Medical School, UK
Curr Opin Gastroenterol 21:712-6. 2005..Combined supplementation of bioactive fibers and lactic acid bacteria (synbiotics) directly and indirectly influences several of these factors...
- Curcumin, an atoxic antioxidant and natural NFkappaB, cyclooxygenase-2, lipooxygenase, and inducible nitric oxide synthase inhibitor: a shield against acute and chronic diseasesStig Bengmark
Institute of Hepatology, University College, London Medical School, London, United Kingdom
JPEN J Parenter Enteral Nutr 30:45-51. 2006..Drugs developed by the pharmaceutical industry have thus far been associated with toxicity and side effects, which is why natural substances are of increasing interest...
- [The bioecological medicine is here to stay. About microflora, synbiotics, immunity and resistance against disease]Stig Bengmark
University College, Londons universitet
Lakartidningen 103:293-7. 2006
- Bioecologic control of inflammation and infection in critical illnessStig Bengmark
Institute of Hepatology, University College London Medical School, 69 75 Chenies Mews, London WC1E 6HX, UK
Anesthesiol Clin 24:299-323, vi. 2006..Side effects and price constitute important obstacles, especially when it comes to use of cytokine antagonists and inhibitors...
- Bioecological control of inflammatory bowel diseaseStig Bengmark
UCL Department of Hepatology, University College, London Medical School, 69 75 Chenies Mews, London WC1E 6HX, UK
Clin Nutr 26:169-81. 2007..The general experience this far is that the best effects are obtained with compositions of probiotics rather than with single LAB treatments...
- Aggressive management of surgical emergenciesStig Bengmark
Institute of Hepatology, University College London, London, UK
Ann R Coll Surg Engl 88:624-9. 2006..Immediate control of inflammation by enteral nutrition and supply of antioxidants, lactic acid bacteria and fibres is facilitated by feeding tubes, introduced as early as possible on arrival at the hospital...
- Advanced glycation and lipoxidation end products--amplifiers of inflammation: the role of foodStig Bengmark
UCL Institute of Hepatology, University College, London Medical School, London, United Kingdom
JPEN J Parenter Enteral Nutr 31:430-40. 2007..These molecules are strongly associated with activation of a specific receptor called RAGE and a long-lasting exaggerated level of inflammation in the body...
- [The emergency admission misery--seen from the inside...]Stig Bengmark
UCL, London, UK
Lakartidningen 103:2308-9. 2006
- Gut microbial ecology in critical illness: is there a role for prebiotics, probiotics, and synbiotics?Stig Bengmark
Department of Hepatology, University College of London, Liver Institute, London, UK
Curr Opin Crit Care 8:145-51. 2002....
- Use of some pre-, pro- and synbiotics in critically ill patientsStig Bengmark
Department of Hepatology, London Medical School, University College, Liver Institute, 69 75 Chenies Mews, London WC1E 6HX, UK
Best Pract Res Clin Gastroenterol 17:833-48. 2003..This is especially important as pharmaceutical treatment, including the use of antibiotics, has largely failed, and the medical world is in much need of new treatment paradigms...
- [Biological control--a better way of controlling infections]Stig Bengmark
Lakartidningen 101:2129-30; discussion 2131. 2004
- Bio-ecological control of perioperative and ITU morbidityStig Bengmark
Departments of Hepatology and Surgery, University College, London Medical School, 69 75 Chenies Mews, London WC1E 6HX, UK
Langenbecks Arch Surg 389:145-54. 2004..Nutritional control of postoperative morbidity includes use of so-called synbiotics, e.g. a combination of bioactive lactic acid bacteria (LAB) and bioactive plant fibres...
- Pre-, pro- and synbioticsS Bengmark
Liver Institute, University College London, UK
Curr Opin Clin Nutr Metab Care 4:571-9. 2001..This review summarizes the present experience in various forms of diarrhoea, inflammatory bowel disease, and Helicobacter infections, in intensive care patients and in connection with extensive surgery...
- [Bio-ecological control of chronic liver disease and encephalopathy]S Bengmark
Division of Surgery and Interventional Science, University College, London, UK
Minerva Med 102:309-19. 2011..Subsequent studies with other lactic acid bacteria seem to demonstrate suppression of inflammation and one study also provides evidence of clinical improvement...
- Enteral nutrition in HPB surgery: past and futureStig Bengmark
Departments of Hepatology and Surgery, University College, 69 75 Chenies Mews, WC1E 6HX, London, UK
J Hepatobiliary Pancreat Surg 9:448-58. 2002..It is essential that the nutrition also provides food for the colon, e.g., fiber and healthy bacteria (probiotics) to ferment the fiber and boost the immune system...
- Plant-derived health: the effects of turmeric and curcuminoidsS Bengmark
Institute of Hepatology, University College London Medical School, London
Nutr Hosp 24:273-81. 2009....
- Gut microenvironment and immune functionS Bengmark
Lund University, Ideon Research Center, Sweden
Curr Opin Clin Nutr Metab Care 2:83-5. 1999..Lack of compliance with these requests seems to explain the lack of consistency in clinical experience of enteral nutrition, when tried in connection with trauma and clinical surgery...
- Enteric bacterial translocation after intraperitoneal implantation of rubber drain piecesW Guo
Dept of Surgery, Lund University, Sweden
Scand J Gastroenterol 28:393-400. 1993....
- Acute and "chronic" phase reaction-a mother of diseaseStig Bengmark
Department of Surgery and Liver Institute, UCL, London, UK
Clin Nutr 23:1256-66. 2004..The need for studies with lifestyle modifications is especially emphasized...
- Bioecological and nutritional control of disease: prebiotics, probiotics and synbioticsS Bengmark
Department of Hepatology, Institute of Hepatology, University College London Medical School, 69 75 Chenies Mews, London, WC1E 6HX, United Kingdom
Nutr Hosp 21:72-84, 73-86. 2006..Further studies are needed to ascertain the molecular mechanisms by which pre-, pro- and synbiotics influence the outcome in a variety of acute and chronic diseases...
- Effect of enteral nutrition and synbiotics on bacterial infection rates after pylorus-preserving pancreatoduodenectomy: a randomized, double-blind trialNada Rayes
Department of General, Visceral and Transplant Surgery, Charite Campus Virchow, Humboldt University, Berlin, Germany
Ann Surg 246:36-41. 2007..Patients undergoing pancreas resection carry several risk factors for nosocomial bacterial infections. Pre- and probiotics (synbiotics) are potentially useful for prevention of these infections...
- Synbiotic control of inflammation and infection in severe acute pancreatitis: a prospective, randomized, double blind studyAttila Olah
Department of Surgery, Petz Aladar Teaching Hospital, Gyor, Hungary
Hepatogastroenterology 54:590-4. 2007..In a prospective, randomized, double-blinded study the role of "Synbiotic 2000", a new synbiotic composition with high colony forming unit (CFU) was evaluated in the treatment of severe acute pancreatitis...
- Early enteral supply of lactobacillus and fiber versus selective bowel decontamination: a controlled trial in liver transplant recipientsNada Rayes
Department of Surgery, Charite Campus Virchow, Berlin, Germany
Transplantation 74:123-7. 2002..Early enteral nutrition with solutions containing prebiotics (fiber) and probiotics (Lactobacillus) is suggested to reduce bacterial translocation and minimize the incidence of infections after liver transplantation...
- Early enteral supply of fiber and Lactobacilli versus conventional nutrition: a controlled trial in patients with major abdominal surgeryNada Rayes
Department of Surgery, Charite, Campus Virchow, Augustenberger Platz 1, 13355 Berlin, Germany
Nutrition 18:609-15. 2002..Early enteral nutrition with fiber-containing solutions plus Lactobacillus may reduce bacterial translocation and minimize the incidence of infections after surgery...
- Synbiotics, prebiotics, glutamine, or peptide in early enteral nutrition: a randomized study in trauma patientsAlenka Spindler-Vesel
University Medical Centre, Ljubljana, Slovenia
JPEN J Parenter Enteral Nutr 31:119-26. 2007....
- Azathioprine and mesalazine-induced effects on the mucosal flora in patients with IBD colitisAlexander Swidsinski
Humboldt University, Charite Hospital, CCM, Laboratory for Molecular Genetics, Polymicrobial Infections and Bacterial Biofilms, 10098 Berlin, Germany
Inflamm Bowel Dis 13:51-6. 2007..The study investigated the influence of IBD treatment on the concentrations and spatial organization of mucosal bacteria using fluorescence in situ hybridization with 16s r-RNA targeting probes...
- Pretreatment with pro- and synbiotics reduces peritonitis-induced acute lung injury in ratsDemet Tok
Department of Anesthesiology, Celal Bayar University, Turkey
J Trauma 62:880-5. 2007..To study whether enteral pretreatment with a synbiotic composition of lactic acid bacteria and bioactive fibers can reduce peritonitis-induced lung neutrophil infiltration and tissue injury in rats...
- Supply of pre- and probiotics reduces bacterial infection rates after liver transplantation--a randomized, double-blind trialNada Rayes
Department of General, Visceral and Transplant Surgery, Charite Campus Virchow, Humboldt University, Berlin, Germany
Am J Transplant 5:125-30. 2005..Early enteral nutrition supplemented with a mixture of LAB and fibers reduces bacterial infection rates following liver transplantation. Treatment with only fibers led to a low incidence of severe infections...
- Modulation by enteral nutrition of the acute phase response and immune functionsStig Bengmark
Departamento de Cirugia, Universidad de Lund, Suecia
Nutr Hosp 18:1-5. 2003....
- Comparative study of the intestinal mucus barrier in normal and inflamed colonAlexander Swidsinski
Humboldt University, Charite, CCM, 10098 Berlin, Germany
Gut 56:343-50. 2007..To study the role of mucus in the spatial separation of intestinal bacteria from mucosa...
- Synbiotics to strengthen gut barrier function and reduce morbidity in critically ill patientsStig Bengmark
Clin Nutr 23:441-5. 2004
- Synbiotic modulation of gut flora: effect on minimal hepatic encephalopathy in patients with cirrhosisQing Liu
Artificial Liver Treatment and Training Center, Beijing Youan Hospital and Capital University of Medical Sciences, Beijing, China
Hepatology 39:1441-9. 2004..In conclusion, treatment with synbiotics or fermentable fiber is an alternative to lactulose for the management of MHE in patients with cirrhosis...
- Probiotics partly reverse increased bacterial translocation after simultaneous liver resection and colonic anastomosis in ratsDaniel Seehofer
Department of General, Visceral, and Transplant Surgery, Charite, Campus Virchow, Humboldt University of Berlin, Augustenburger Platz 1, D 13353 Berlin, Germany
J Surg Res 117:262-71. 2004..Bacterial translocation is one important cause of nosocomial infections following major abdominal surgery. Oral administration of probiotics has been proposed to diminish bacterial translocation...
- Probiotics: a practical review of their role in specific clinical scenariosBarry Jenkins
Department of Surgery, Medical College of Georgia, 1120 15th St, BI 4072, Augusta, GA 30912, USA
Nutr Clin Pract 20:262-70. 2005..In the arena of probiotics, numerous fundamental questions remain unanswered...
- Failure of Synbiotic 2000 to prevent postoperative recurrence of Crohn's diseaseIrit Chermesh
Gastroenterology Department, Rambam Health Care Campus, Haifa, Israel
Dig Dis Sci 52:385-9. 2007..Larger studies in patients with the inflammatory type of CD undergoing surgery, using higher doses of probiotics cocktail might prove effective...
- Lactobacilli attenuate bacteremia and endotoxemia associated with severe intra-abdominal infectionHenrik Thorlacius
Department of Surgery, Malmo University Hospital, Malmo, Sweden
Surgery 134:467-73. 2003..In this study, we wanted to compare the protective effect of enteral administration of lactobacilli to gentamicin against severe intra-abdominal infection...
- Probiotics in health and disease in the pediatric patientJonathan E Markowitz
Department of Pediatrics, Division of Gastroenterology and Nutrition, University of Pennsylvania School of Medicine, Children s Hospital of Philadelphia, Philadelphia, Pennsylvania, USA
Pediatr Clin North Am 49:127-41. 2002....
- Bacterial biofilm suppression with antibiotics for ulcerative and indeterminate colitis: consequences of aggressive treatmentAlexander Swidsinski
Humboldt University, Charite Hospital, CCM, Laboratory for Molecular Genetics, Polymicrobial Infections and Biofilms, Berlin, Germany
Arch Med Res 39:198-204. 2008..Antibiotics are commonly used in inflammatory bowel disease (IBD). Little is known about their effect on the mucosal flora...
- Peripheral blood mononuclear cell expression of toll-like receptors and relation to cytokine levels in cirrhosisStephen M Riordan
Gastrointestinal and Liver Unit, The Prince of Wales Hospital and University of New South Wales, Sydney, Australia
Hepatology 37:1154-64. 2003..TLR2 likely contributes to increased circulating TNF-alpha and sTNFR levels in cirrhosis...
- Probiotics potentiate IL-6 production in IL-1beta-treated Caco-2 cells through a heat shock-dependent mechanismNatasha Reilly
Department of Surgery, Beth Israel Deaconess Medical Center, 330 Brookline Ave, Boston, MA 02215, USA
Am J Physiol Regul Integr Comp Physiol 293:R1169-79. 2007..Results suggest that probiotics may enhance IL-6 production in enterocytes subjected to an inflammatory stimulus and that this effect may, at least in part, be heat shock dependent...
- NF-kappaB- and AP-1-mediated induction of human beta defensin-2 in intestinal epithelial cells by Escherichia coli Nissle 1917: a novel effect of a probiotic bacteriumJan Wehkamp
Department of Internal Medicine I, Robert Bosch Hospital, Stuttgart, Germany
Infect Immun 72:5750-8. 2004..The induction of hBD-2 may contribute to an enhanced mucosal barrier to the luminal bacteria...