Robert Belshaw

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. pmc Why genes overlap in viruses
    Nicola Chirico
    Department of Structural and Functional Biology, University of Insubria, via JH Dunant 3, 21100 Varese, Italy
    Proc Biol Sci 277:3809-17. 2010
  2. ncbi request reprint Viral mutation and substitution: units and levels
    Robert Belshaw
    Department of Zoology, University of Oxford, Oxford OX1 3PS, United Kingdom
    Curr Opin Virol 1:430-5. 2011
  3. pmc The RNA virus database
    Robert Belshaw
    Department of Zoology, University of Oxford, Oxford OX1 3PS, UK
    Nucleic Acids Res 37:D431-5. 2009
  4. pmc The evolution of genome compression and genomic novelty in RNA viruses
    Robert Belshaw
    Department of Zoology, University of Oxford, Oxford OX1 3PS, United Kingdom
    Genome Res 17:1496-504. 2007
  5. pmc Rate of recombinational deletion among human endogenous retroviruses
    Robert Belshaw
    Department of Zoology, University of Oxford, Oxford OX1 3PS, United Kingdom
    J Virol 81:9437-42. 2007
  6. doi request reprint Pacing a small cage: mutation and RNA viruses
    Robert Belshaw
    Department of Zoology, University of Oxford, Oxford, UK
    Trends Ecol Evol 23:188-93. 2008
  7. ncbi request reprint The rise and falls of introns
    R Belshaw
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Heredity (Edinb) 96:208-13. 2006
  8. pmc Genomewide screening reveals high levels of insertional polymorphism in the human endogenous retrovirus family HERV-K(HML2): implications for present-day activity
    Robert Belshaw
    Department of Biological Sciences, Imperial College, Ascot, Berks, United Kingdom
    J Virol 79:12507-14. 2005
  9. ncbi request reprint Phylogenetic evidence for deleterious mutation load in RNA viruses and its contribution to viral evolution
    Oliver G Pybus
    Department of Zoology, University of Oxford, Oxford, United Kingdom
    Mol Biol Evol 24:845-52. 2007
  10. pmc Conserved footprints of APOBEC3G on Hypermutated human immunodeficiency virus type 1 and human endogenous retrovirus HERV-K(HML2) sequences
    Andrew E Armitage
    MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, United Kingdom
    J Virol 82:8743-61. 2008

Collaborators

Detail Information

Publications20

  1. pmc Why genes overlap in viruses
    Nicola Chirico
    Department of Structural and Functional Biology, University of Insubria, via JH Dunant 3, 21100 Varese, Italy
    Proc Biol Sci 277:3809-17. 2010
    ..We consider that these patterns cannot be explained by other factors, namely the possible roles of overlap in transcription regulation, generating more divergent proteins and the relationship between gene length and genome length...
  2. ncbi request reprint Viral mutation and substitution: units and levels
    Robert Belshaw
    Department of Zoology, University of Oxford, Oxford OX1 3PS, United Kingdom
    Curr Opin Virol 1:430-5. 2011
    ..A better understanding of the complexities underlying the molecular evolution of viruses in natural populations is needed before accurate predictions of viral evolution can be made...
  3. pmc The RNA virus database
    Robert Belshaw
    Department of Zoology, University of Oxford, Oxford OX1 3PS, UK
    Nucleic Acids Res 37:D431-5. 2009
    ..It is available at the following four mirrored sites. http://virus.zoo.ox.ac.uk/rnavirusdb; http://hivweb.sanbi.ac.za/rnavirusdb; http://bioinf.cs.auckland.ac.nz/rnavirusdb; http://tree.bio.ed.ac.uk/rnavirusdb...
  4. pmc The evolution of genome compression and genomic novelty in RNA viruses
    Robert Belshaw
    Department of Zoology, University of Oxford, Oxford OX1 3PS, United Kingdom
    Genome Res 17:1496-504. 2007
    ..We suggest that RNA viruses are a good model system for the investigation of general evolutionary relationship between genome attributes such as mutational robustness, mutation rate, and size...
  5. pmc Rate of recombinational deletion among human endogenous retroviruses
    Robert Belshaw
    Department of Zoology, University of Oxford, Oxford OX1 3PS, United Kingdom
    J Virol 81:9437-42. 2007
    ....
  6. doi request reprint Pacing a small cage: mutation and RNA viruses
    Robert Belshaw
    Department of Zoology, University of Oxford, Oxford, UK
    Trends Ecol Evol 23:188-93. 2008
    ..We explain the many terms used in investigating RNA viral evolution and highlight the specific experimental and comparative work that needs to be done...
  7. ncbi request reprint The rise and falls of introns
    R Belshaw
    Department of Zoology, University of Oxford, South Parks Road, Oxford OX1 3PS, UK
    Heredity (Edinb) 96:208-13. 2006
    ....
  8. pmc Genomewide screening reveals high levels of insertional polymorphism in the human endogenous retrovirus family HERV-K(HML2): implications for present-day activity
    Robert Belshaw
    Department of Biological Sciences, Imperial College, Ascot, Berks, United Kingdom
    J Virol 79:12507-14. 2005
    ..This view of the family from a population perspective rather than a genome perspective will inform the current debate about a possible role of HERV-K(HML2) in human disease...
  9. ncbi request reprint Phylogenetic evidence for deleterious mutation load in RNA viruses and its contribution to viral evolution
    Oliver G Pybus
    Department of Zoology, University of Oxford, Oxford, United Kingdom
    Mol Biol Evol 24:845-52. 2007
    ..From this relationship, we propose an empirical threshold for the maximum viable deleterious mutation load in RNA viruses...
  10. pmc Conserved footprints of APOBEC3G on Hypermutated human immunodeficiency virus type 1 and human endogenous retrovirus HERV-K(HML2) sequences
    Andrew E Armitage
    MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, Oxford, United Kingdom
    J Virol 82:8743-61. 2008
    ....
  11. pmc Long-term reinfection of the human genome by endogenous retroviruses
    Robert Belshaw
    Department of Biological Sciences, Imperial College at Silwood Park, Ascot, Berks SL5 7PY, United Kingdom
    Proc Natl Acad Sci U S A 101:4894-9. 2004
    ..Analysis of the env gene of eight other HERV families indicated that reinfection is likely to be the most common mechanism by which endogenous retroviruses proliferate in their hosts...
  12. pmc 'There and back again': revisiting the pathophysiological roles of human endogenous retroviruses in the post-genomic era
    Gkikas Magiorkinis
    Department of Zoology, University of Oxford, Oxford OX1 3PS, UK
    Philos Trans R Soc Lond B Biol Sci 368:20120504. 2013
    ..We also pose two thought-provoking research questions on potential pathophysiological roles of ERVs with respect to immune escape and regulation. ..
  13. pmc Env-less endogenous retroviruses are genomic superspreaders
    Gkikas Magiorkinis
    Department of Zoology, University of Oxford, Oxford OX1 3PS, United Kingdom
    Proc Natl Acad Sci U S A 109:7385-90. 2012
    ....
  14. ncbi request reprint BlastAlign: a program that uses blast to align problematic nucleotide sequences
    Robert Belshaw
    Department of Biological Sciences, Imperial College Silwood Park Campus, Ascot, Berks SL5 7PY, UK
    Bioinformatics 21:122-3. 2005
    ..An additional Perl program BlastAlignP uses tblastn to align nucleotide sequences to a single amino acid sequence, thus allowing an open reading frame to be maintained in the resulting multiple alignment...
  15. doi request reprint Neanderthal and Denisovan retroviruses in modern humans
    Emanuele Marchi
    Department of Zoology, University of Oxford, Oxford OX1 3PS, UK
    Curr Biol 23:R994-5. 2013
    ..We explain this apparent contradiction using population genetic theory and suggest that it illustrates an important phenomenon for the study of transposable elements such as ERVs. ..
  16. pmc Integrating phylodynamics and epidemiology to estimate transmission diversity in viral epidemics
    Gkikas Magiorkinis
    Department of Hygiene, Epidemiology and Medical Statistics, Medical School, University of Athens, Athens, Greece
    PLoS Comput Biol 9:e1002876. 2013
    ..We anticipate that this integrated approach will form the basis of powerful tools for describing the transmission dynamics of chronic viral diseases, and for evaluating control strategies directed against them...
  17. pmc Detecting remote sequence homology in disordered proteins: discovery of conserved motifs in the N-termini of Mononegavirales phosphoproteins
    David Karlin
    Department of Zoology, University of Oxford, Oxford, United Kingdom
    PLoS ONE 7:e31719. 2012
    ....
  18. ncbi request reprint Robustness of ancestral state estimates: evolution of life history strategy in ichneumonoid parasitoids
    Robert Belshaw
    Department of Biological Sciences, Imperial College at Silwood Park, Ascot, Berkshire SL5 7PY, UK
    Syst Biol 51:450-77. 2002
    ..We also discuss relationships within the superfamily and expand the Mesostoinae to include all the gall-associated braconids that form the sister group of the Aphidiinae...
  19. ncbi request reprint Morphometric and molecular analysis of the Encarsia inaron species-group (Hymenoptera: Aphelinidae), parasitoids of whiteflies (Hemiptera: Aleyrodidae)
    S Manzari
    Department of Biological Sciences, Imperial College of Science, Technology and Medicine, Silwood Park, Ascot, Berkshire, SL5 7PY, UK
    Bull Entomol Res 92:165-76. 2002
    ..estrellae, and the placement of E. dichroa (Mercet) in the E. inaron species-group. Additionally, E. inaron is redescribed and some taxonomic problems in the E. inaron species-group are discussed...
  20. ncbi request reprint High copy number in human endogenous retrovirus families is associated with copying mechanisms in addition to reinfection
    Robert Belshaw
    Mol Biol Evol 22:814-7. 2005
    ..We discuss why these other mechanisms are rare in most families and suggest why complementation in trans is significant only in the larger families...