D R Bell

Summary

Affiliation: University of Nottingham
Country: UK

Publications

  1. ncbi request reprint Binding of aryl hydrocarbon receptor (AhR) to AhR-interacting protein. The role of hsp90
    D R Bell
    Centers for Disease Control, National Institute for Occupational Safety and Health, Health Effects Laboratory Division, Morgantown, West Virginia 26505, USA
    J Biol Chem 275:36407-14. 2000
  2. ncbi request reprint Toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the developing male Wistar(Han) rat. II: Chronic dosing causes developmental delay
    David R Bell
    School of Biology, University of Nottingham, University Park, Nottingham, NG7 2RD, UK
    Toxicol Sci 99:224-33. 2007
  3. ncbi request reprint Toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the developing male Wistar(Han) rat. I: No decrease in epididymal sperm count after a single acute dose
    David R Bell
    School of Biology, University of Nottingham, University Park, Nottingham NG7 2RD, UK
    Toxicol Sci 99:214-23. 2007
  4. ncbi request reprint Relationships between tissue levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), mRNAs, and toxicity in the developing male Wistar(Han) rat
    David R Bell
    School of Biology, University of Nottingham, University Park, Nottingham NG7 2RD, United Kingdom
    Toxicol Sci 99:591-604. 2007
  5. pmc Species-specific induction of cytochrome P-450 4A RNAs: PCR cloning of partial guinea-pig, human and mouse CYP4A cDNAs
    D R Bell
    Department of Life Science, University of Nottingham, University Park, U K
    Biochem J 294:173-80. 1993
  6. pmc Molecular basis of non-responsiveness to peroxisome proliferators: the guinea-pig PPARalpha is functional and mediates peroxisome proliferator-induced hypolipidaemia
    A R Bell
    School of Biology, University of Nottingham, University Park, Nottingham NG7 2RD, UK
    Biochem J 332:689-93. 1998

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Binding of aryl hydrocarbon receptor (AhR) to AhR-interacting protein. The role of hsp90
    D R Bell
    Centers for Disease Control, National Institute for Occupational Safety and Health, Health Effects Laboratory Division, Morgantown, West Virginia 26505, USA
    J Biol Chem 275:36407-14. 2000
    ..The data support a model where 1) AIP binds to both hsp90 and AhR; 2) hsp90 is required for AhR-AIP binding; and 3) the binding of AhR to AIP stabilizes the AIP-hsp90-AhR complex...
  2. ncbi request reprint Toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the developing male Wistar(Han) rat. II: Chronic dosing causes developmental delay
    David R Bell
    School of Biology, University of Nottingham, University Park, Nottingham, NG7 2RD, UK
    Toxicol Sci 99:224-33. 2007
    ....
  3. ncbi request reprint Toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin in the developing male Wistar(Han) rat. I: No decrease in epididymal sperm count after a single acute dose
    David R Bell
    School of Biology, University of Nottingham, University Park, Nottingham NG7 2RD, UK
    Toxicol Sci 99:214-23. 2007
    ..These data show that TCDD is a potent developmental toxin after exposure of the developing fetus but that acute developmental exposure to TCDD on GD15 caused no decrease in sperm counts...
  4. ncbi request reprint Relationships between tissue levels of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD), mRNAs, and toxicity in the developing male Wistar(Han) rat
    David R Bell
    School of Biology, University of Nottingham, University Park, Nottingham NG7 2RD, United Kingdom
    Toxicol Sci 99:591-604. 2007
    ..These data characterize the maternal and fetal disposition of TCDD, induction of CYP1A1 RNA as a measure of AhR activation, and suggest that lactational transfer of TCDD determines the difference in delay in BPS between the two studies...
  5. pmc Species-specific induction of cytochrome P-450 4A RNAs: PCR cloning of partial guinea-pig, human and mouse CYP4A cDNAs
    D R Bell
    Department of Life Science, University of Nottingham, University Park, U K
    Biochem J 294:173-80. 1993
    ..These findings are consistent with a species difference in response to peroxisome proliferators between the rat/mouse and the guinea pig...
  6. pmc Molecular basis of non-responsiveness to peroxisome proliferators: the guinea-pig PPARalpha is functional and mediates peroxisome proliferator-induced hypolipidaemia
    A R Bell
    School of Biology, University of Nottingham, University Park, Nottingham NG7 2RD, UK
    Biochem J 332:689-93. 1998
    ..Thus the guinea pig is a useful model for human responses to peroxisome proliferators...