Esther B E Becker

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. ncbi request reprint Autism spectrum disorder and the cerebellum
    Esther B E Becker
    MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom Electronic address
    Int Rev Neurobiol 113:1-34. 2013
  2. pmc Candidate screening of the TRPC3 gene in cerebellar ataxia
    Esther B E Becker
    MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford, OX1 3QX, UK
    Cerebellum 10:296-9. 2011
  3. pmc Early onset of ataxia in moonwalker mice is accompanied by complete ablation of type II unipolar brush cells and Purkinje cell dysfunction
    Gabriella Sekerkova
    Departments of Physiology and Cell and Molecular Biology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, Department of Physiology, Anatomy, and Genetics, MRC Functional Genomics Unit, Oxford OX1 3PT, United Kingdom, Institute of Neuroscience, Technical University Munich, 80802 Munich, Germany, and Laboratory of Neurobiology, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Durham, North Carolina 27709
    J Neurosci 33:19689-94. 2013
  4. pmc Oxr1 is essential for protection against oxidative stress-induced neurodegeneration
    Peter L Oliver
    Medical Research Council Functional Genomics Unit, Department of Physiology, Anatomy, and Genetics, University of Oxford, Oxford, United Kingdom
    PLoS Genet 7:e1002338. 2011
  5. pmc Contactin-associated protein-2 antibodies in non-paraneoplastic cerebellar ataxia
    Esther B E Becker
    Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford University, Oxford, UK
    J Neurol Neurosurg Psychiatry 83:437-40. 2012
  6. pmc A point mutation in TRPC3 causes abnormal Purkinje cell development and cerebellar ataxia in moonwalker mice
    Esther B E Becker
    Medical Research Council Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, United Kingdom
    Proc Natl Acad Sci U S A 106:6706-11. 2009

Collaborators

Detail Information

Publications6

  1. ncbi request reprint Autism spectrum disorder and the cerebellum
    Esther B E Becker
    MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, Oxford, United Kingdom Electronic address
    Int Rev Neurobiol 113:1-34. 2013
    ....
  2. pmc Candidate screening of the TRPC3 gene in cerebellar ataxia
    Esther B E Becker
    MRC Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford, OX1 3QX, UK
    Cerebellum 10:296-9. 2011
    ..We identified a number of variants but no causative mutations in TRPC3. Our findings suggest that mutations in TRPC3 do not significantly contribute to the cause of late-onset and episodic human cerebellar ataxias...
  3. pmc Early onset of ataxia in moonwalker mice is accompanied by complete ablation of type II unipolar brush cells and Purkinje cell dysfunction
    Gabriella Sekerkova
    Departments of Physiology and Cell and Molecular Biology, Northwestern University Feinberg School of Medicine, Chicago, Illinois 60611, Department of Physiology, Anatomy, and Genetics, MRC Functional Genomics Unit, Oxford OX1 3PT, United Kingdom, Institute of Neuroscience, Technical University Munich, 80802 Munich, Germany, and Laboratory of Neurobiology, National Institute of Environmental Health Sciences, National Institutes of Health, Department of Health and Human Services, Durham, North Carolina 27709
    J Neurosci 33:19689-94. 2013
    ....
  4. pmc Oxr1 is essential for protection against oxidative stress-induced neurodegeneration
    Peter L Oliver
    Medical Research Council Functional Genomics Unit, Department of Physiology, Anatomy, and Genetics, University of Oxford, Oxford, United Kingdom
    PLoS Genet 7:e1002338. 2011
    ..Finally we show up-regulation of Oxr1 in both human and pre-symptomatic mouse models of amyotrophic lateral sclerosis, indicating that Oxr1 is potentially a novel neuroprotective factor in neurodegenerative disease...
  5. pmc Contactin-associated protein-2 antibodies in non-paraneoplastic cerebellar ataxia
    Esther B E Becker
    Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford University, Oxford, UK
    J Neurol Neurosurg Psychiatry 83:437-40. 2012
    ..Relatively few studies have searched for potentially pathogenic antibodies in non-paraneoplastic patients with cerebellar ataxia...
  6. pmc A point mutation in TRPC3 causes abnormal Purkinje cell development and cerebellar ataxia in moonwalker mice
    Esther B E Becker
    Medical Research Council Functional Genomics Unit, Department of Physiology, Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, United Kingdom
    Proc Natl Acad Sci U S A 106:6706-11. 2009
    ..Our findings define a previously unknown role for TRPC3 in both dendritic development and survival of Purkinje cells, and provide a unique mechanism underlying cerebellar ataxia...