Sonja Baumli

Summary

Affiliation: University of Newcastle
Country: UK

Publications

  1. pmc The CDK9 C-helix exhibits conformational plasticity that may explain the selectivity of CAN508
    Sonja Baumli
    Northern Institute for Cancer Research, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, U K
    ACS Chem Biol 7:811-6. 2012
  2. pmc The CDK9 tail determines the reaction pathway of positive transcription elongation factor b
    Sonja Baumli
    Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne NE2 4HH, UK
    Structure 20:1788-95. 2012

Detail Information

Publications2

  1. pmc The CDK9 C-helix exhibits conformational plasticity that may explain the selectivity of CAN508
    Sonja Baumli
    Northern Institute for Cancer Research, Newcastle University, Framlington Place, Newcastle upon Tyne NE2 4HH, U K
    ACS Chem Biol 7:811-6. 2012
    ..By comparison with a previously published structure of CDK9/cyclin T/human immunodeficiency virus TAT we find that the CDK9 αC-helix has a degree of conformational variability that has the potential to be exploited for inhibitor design...
  2. pmc The CDK9 tail determines the reaction pathway of positive transcription elongation factor b
    Sonja Baumli
    Northern Institute for Cancer Research, Newcastle University, Newcastle upon Tyne NE2 4HH, UK
    Structure 20:1788-95. 2012
    ..We propose that this mechanism is critical for the pattern of CTD Ser2 phosphorylation on actively transcribed genes...