Research Topics
Species | Jennifer H BarnettSummaryAffiliation: University of Cambridge Country: UK Publications
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Detail Information
Publications
Childhood cognitive function and adult psychopathology: associations with psychotic and non-psychotic symptoms in the general populationJennifer H Barnett
Department of Psychiatry, Addenbrooke s Hospital, Cambridge, UK
Br J Psychiatry 201:124-30. 2012..Lower cognitive ability in childhood is associated with increased risk of future schizophrenia, but its relationship with adult psychotic-like experiences and other psychopathology is less understood...
Cognitive effects of genetic variation in monoamine neurotransmitter systems: a population-based study of COMT, MAOA, and 5HTTLPRJennifer H Barnett
Department of Psychiatry, University of Cambridge, Cambridge, UK
Am J Med Genet B Neuropsychiatr Genet 156:158-67. 2011..These results suggest that assessment of multiple genes within functionally related systems may improve our understanding of the genetic basis of cognition...
Assessing cognitive function in clinical trials of schizophreniaJennifer H Barnett
Department of Psychiatry, University of Cambridge, Cambridge, UK
Neurosci Biobehav Rev 34:1161-77. 2010..Computerised cognitive assessment may optimise the statistical power of cognitive trials by reducing measurement error and between-site variability and decreasing patient attrition through increased tolerability...
Effects of catechol-O-methyltransferase on normal variation in the cognitive function of childrenJennifer H Barnett
Department of Psychiatryand the Centre for Family Research, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
Am J Psychiatry 166:909-16. 2009..The authors tested the hypothesis that a more informative COMT haplotype predicts normal cognitive development in a large population-based cohort of children enrolled in the Avon Longitudinal Study of Parents and Children...
Substance use in a population-based clinic sample of people with first-episode psychosisJennifer H Barnett
Department of Psychiatry, Box 189, University of Cambridge, UK
Br J Psychiatry 190:515-20. 2007..Substance use is implicated in the cause and course of psychosis...
Improvement and decline of cognitive function in schizophrenia over one year: a longitudinal investigation using latent growth modellingJennifer H Barnett
University of Cambridge Department of Psychiatry, Addenbrooke s Hospital, Cambridge, UK
BMC Psychiatry 7:16. 2007..Long-term follow-up studies of people with schizophrenia report stability of cognitive performance; less is known about any shorter-term changes in cognitive function...
Visuospatial learning and executive function are independently impaired in first-episode psychosisJennifer H Barnett
University of Cambridge Department of Psychiatry, Box 189, Addenbrooke s Hospital, Cambridge CB2 2QQ, UK
Psychol Med 35:1031-41. 2005....
Gender-specific effects of the catechol-O-methyltransferase Val108/158Met polymorphism on cognitive function in childrenJennifer H Barnett
University of Cambridge, Department of Psychiatry, Box 189, Addenbrooke s Hospital, Cambridge CB2 2QQ, UK
Am J Psychiatry 164:142-9. 2007..This polymorphism affects cognitive function in healthy adults and may contribute to risk for schizophrenia...
Effects of the catechol-O-methyltransferase Val158Met polymorphism on executive function: a meta-analysis of the Wisconsin Card Sort Test in schizophrenia and healthy controlsJ H Barnett
Department of Psychiatry, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
Mol Psychiatry 12:502-9. 2007..There was no evidence of publication bias. We conclude that there is small but significant relationship between Val(158)Met genotype and executive function in healthy individuals but not in schizophrenia...
No association of COMT (Val158Met) genotype with brain structure differences between men and womenAnna Barnes
Department of Psychiatry, University of Cambridge, Addenbrooke s Hospital, Cambridge, United Kingdom
PLoS ONE 7:e33964. 2012....
Effects of modafinil on cognitive functions in first episode psychosisLinda Scoriels
Department of Psychiatry, University of Cambridge, Herchel Smith Building for Brain and Mind Sciences, Cambridge Biomedical Campus, Cambridge, CB2 0SZ, UK
Psychopharmacology (Berl) 220:249-58. 2012..Modafinil is a wake-promoting drug that has been shown to improve attention, memory and executive function in the healthy population and in patients with schizophrenia...
Neuregulin-1 genotype is associated with structural differences in the normal human brainAnna Barnes
Department of Psychiatry, University of Cambridge, Box 189 Addenbrooke s Hospital, Cambridge CB2 2QQ, UK
Neuroimage 59:2057-61. 2012..These results suggest that this genetic variant may mediate risk for schizophrenia, in part, through its effect on brain structure in these regions...
Translational approaches to frontostriatal dysfunction in attention-deficit/hyperactivity disorder using a computerized neuropsychological batterySamuel R Chamberlain
Department of Psychiatry and Medical Research Council Wellcome Trust Behavioural and Clinical Neurosciences Institute, University of Cambridge, Cambridge, United Kingdom
Biol Psychiatry 69:1192-203. 2011..The findings suggest overlapping but also distinct early cognitive effects of ADHD medications and have important implications for understanding the pathophysiology of ADHD and for future trials...
Effects of modafinil on emotional processing in first episode psychosisLinda Scoriels
Department of Psychiatry, University of Cambridge, Robinson Way, Cambridge, UK
Biol Psychiatry 69:457-64. 2011..We aimed to establish whether modafinil might have a role in the adjuvant treatment of emotional impairments in the first episode of psychosis, when therapeutic endeavor is arguably most vital...
Meta-analysis of the cognitive effects of the catechol-O-methyltransferase gene Val158/108Met polymorphismJennifer H Barnett
Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom
Biol Psychiatry 64:137-44. 2008..We conducted a meta-analysis of reported associations between the COMT Val158/108Met polymorphism and measures of memory and executive function...
A quantitative meta-analysis of population-based studies of premorbid intelligence and schizophreniaGolam M Khandaker
Department of Psychiatry, University of Cambridge, Cambridge, UK
Schizophr Res 132:220-7. 2011....
Reinforcement and reversal learning in first-episode psychosisG K Murray
Brain Mapping Unit, Department of Psychiatry, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
Schizophr Bull 34:848-55. 2008..Abnormalities in reinforcement learning and reversal learning have been reported in psychosis, possibly secondary to subcortical dopamine abnormalities...
Cognitive reserve in neuropsychiatryJ H Barnett
Department of Psychiatry, University of Cambridge School of Clinical Medicine, Addenbrooke's Hospital, Cambridge, UK
Psychol Med 36:1053-64. 2006..It may be possible to enhance cognitive reserve through pharmacological or non-pharmacological means, such as education, neurocognitive activation or other treatment programmes...
