Jennifer H Barnett

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. pmc Cognitive health begins at conception: addressing dementia as a lifelong and preventable condition
    Jennifer H Barnett
    Department of Psychiatry, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 2QQ, UK
    BMC Med 11:246. 2013
  2. pmc Childhood cognitive function and adult psychopathology: associations with psychotic and non-psychotic symptoms in the general population
    Jennifer H Barnett
    Department of Psychiatry, Addenbrooke s Hospital, Cambridge, UK
    Br J Psychiatry 201:124-30. 2012
  3. doi request reprint Assessing cognitive function in clinical trials of schizophrenia
    Jennifer H Barnett
    Department of Psychiatry, University of Cambridge, Cambridge, UK
    Neurosci Biobehav Rev 34:1161-77. 2010
  4. pmc Effects of catechol-O-methyltransferase on normal variation in the cognitive function of children
    Jennifer H Barnett
    Department of Psychiatryand the Centre for Family Research, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
    Am J Psychiatry 166:909-16. 2009
  5. ncbi request reprint Visuospatial learning and executive function are independently impaired in first-episode psychosis
    Jennifer H Barnett
    University of Cambridge Department of Psychiatry, Box 189, Addenbrooke s Hospital, Cambridge CB2 2QQ, UK
    Psychol Med 35:1031-41. 2005
  6. ncbi request reprint Substance use in a population-based clinic sample of people with first-episode psychosis
    Jennifer H Barnett
    Department of Psychiatry, Box 189, University of Cambridge, UK
    Br J Psychiatry 190:515-20. 2007
  7. pmc Improvement and decline of cognitive function in schizophrenia over one year: a longitudinal investigation using latent growth modelling
    Jennifer H Barnett
    University of Cambridge Department of Psychiatry, Addenbrooke s Hospital, Cambridge, UK
    BMC Psychiatry 7:16. 2007
  8. ncbi request reprint Effects of the catechol-O-methyltransferase Val158Met polymorphism on executive function: a meta-analysis of the Wisconsin Card Sort Test in schizophrenia and healthy controls
    J H Barnett
    Department of Psychiatry, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
    Mol Psychiatry 12:502-9. 2007
  9. ncbi request reprint Gender-specific effects of the catechol-O-methyltransferase Val108/158Met polymorphism on cognitive function in children
    Jennifer H Barnett
    University of Cambridge, Department of Psychiatry, Box 189, Addenbrooke s Hospital, Cambridge CB2 2QQ, UK
    Am J Psychiatry 164:142-9. 2007
  10. pmc Cognitive effects of genetic variation in monoamine neurotransmitter systems: a population-based study of COMT, MAOA, and 5HTTLPR
    Jennifer H Barnett
    Department of Psychiatry, University of Cambridge, Cambridge, UK
    Am J Med Genet B Neuropsychiatr Genet 156:158-67. 2011

Detail Information

Publications20

  1. pmc Cognitive health begins at conception: addressing dementia as a lifelong and preventable condition
    Jennifer H Barnett
    Department of Psychiatry, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 2QQ, UK
    BMC Med 11:246. 2013
    ..Because the efficacy of current treatments is limited, increasing efforts are required to prevent the diseases that cause dementia...
  2. pmc Childhood cognitive function and adult psychopathology: associations with psychotic and non-psychotic symptoms in the general population
    Jennifer H Barnett
    Department of Psychiatry, Addenbrooke s Hospital, Cambridge, UK
    Br J Psychiatry 201:124-30. 2012
    ..Lower cognitive ability in childhood is associated with increased risk of future schizophrenia, but its relationship with adult psychotic-like experiences and other psychopathology is less understood...
  3. doi request reprint Assessing cognitive function in clinical trials of schizophrenia
    Jennifer H Barnett
    Department of Psychiatry, University of Cambridge, Cambridge, UK
    Neurosci Biobehav Rev 34:1161-77. 2010
    ..Computerised cognitive assessment may optimise the statistical power of cognitive trials by reducing measurement error and between-site variability and decreasing patient attrition through increased tolerability...
  4. pmc Effects of catechol-O-methyltransferase on normal variation in the cognitive function of children
    Jennifer H Barnett
    Department of Psychiatryand the Centre for Family Research, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
    Am J Psychiatry 166:909-16. 2009
    ..The authors tested the hypothesis that a more informative COMT haplotype predicts normal cognitive development in a large population-based cohort of children enrolled in the Avon Longitudinal Study of Parents and Children...
  5. ncbi request reprint Visuospatial learning and executive function are independently impaired in first-episode psychosis
    Jennifer H Barnett
    University of Cambridge Department of Psychiatry, Box 189, Addenbrooke s Hospital, Cambridge CB2 2QQ, UK
    Psychol Med 35:1031-41. 2005
    ....
  6. ncbi request reprint Substance use in a population-based clinic sample of people with first-episode psychosis
    Jennifer H Barnett
    Department of Psychiatry, Box 189, University of Cambridge, UK
    Br J Psychiatry 190:515-20. 2007
    ..Substance use is implicated in the cause and course of psychosis...
  7. pmc Improvement and decline of cognitive function in schizophrenia over one year: a longitudinal investigation using latent growth modelling
    Jennifer H Barnett
    University of Cambridge Department of Psychiatry, Addenbrooke s Hospital, Cambridge, UK
    BMC Psychiatry 7:16. 2007
    ..Long-term follow-up studies of people with schizophrenia report stability of cognitive performance; less is known about any shorter-term changes in cognitive function...
  8. ncbi request reprint Effects of the catechol-O-methyltransferase Val158Met polymorphism on executive function: a meta-analysis of the Wisconsin Card Sort Test in schizophrenia and healthy controls
    J H Barnett
    Department of Psychiatry, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
    Mol Psychiatry 12:502-9. 2007
    ..There was no evidence of publication bias. We conclude that there is small but significant relationship between Val(158)Met genotype and executive function in healthy individuals but not in schizophrenia...
  9. ncbi request reprint Gender-specific effects of the catechol-O-methyltransferase Val108/158Met polymorphism on cognitive function in children
    Jennifer H Barnett
    University of Cambridge, Department of Psychiatry, Box 189, Addenbrooke s Hospital, Cambridge CB2 2QQ, UK
    Am J Psychiatry 164:142-9. 2007
    ..This polymorphism affects cognitive function in healthy adults and may contribute to risk for schizophrenia...
  10. pmc Cognitive effects of genetic variation in monoamine neurotransmitter systems: a population-based study of COMT, MAOA, and 5HTTLPR
    Jennifer H Barnett
    Department of Psychiatry, University of Cambridge, Cambridge, UK
    Am J Med Genet B Neuropsychiatr Genet 156:158-67. 2011
    ..These results suggest that assessment of multiple genes within functionally related systems may improve our understanding of the genetic basis of cognition...
  11. pmc No association of COMT (Val158Met) genotype with brain structure differences between men and women
    Anna Barnes
    Department of Psychiatry, University of Cambridge, Addenbrooke s Hospital, Cambridge, United Kingdom
    PLoS ONE 7:e33964. 2012
    ....
  12. doi request reprint Effects of modafinil on cognitive functions in first episode psychosis
    Linda Scoriels
    Department of Psychiatry, University of Cambridge, Herchel Smith Building for Brain and Mind Sciences, Cambridge Biomedical Campus, Cambridge, CB2 0SZ, UK
    Psychopharmacology (Berl) 220:249-58. 2012
    ..Modafinil is a wake-promoting drug that has been shown to improve attention, memory and executive function in the healthy population and in patients with schizophrenia...
  13. doi request reprint Neuregulin-1 genotype is associated with structural differences in the normal human brain
    Anna Barnes
    Department of Psychiatry, University of Cambridge, Box 189 Addenbrooke s Hospital, Cambridge CB2 2QQ, UK
    Neuroimage 59:2057-61. 2012
    ..These results suggest that this genetic variant may mediate risk for schizophrenia, in part, through its effect on brain structure in these regions...
  14. doi request reprint Effects of modafinil on emotional processing in first episode psychosis
    Linda Scoriels
    Department of Psychiatry, University of Cambridge, Robinson Way, Cambridge, UK
    Biol Psychiatry 69:457-64. 2011
    ..We aimed to establish whether modafinil might have a role in the adjuvant treatment of emotional impairments in the first episode of psychosis, when therapeutic endeavor is arguably most vital...
  15. doi request reprint Translational approaches to frontostriatal dysfunction in attention-deficit/hyperactivity disorder using a computerized neuropsychological battery
    Samuel R Chamberlain
    Department of Psychiatry and Medical Research Council Wellcome Trust Behavioural and Clinical Neurosciences Institute, University of Cambridge, Cambridge, United Kingdom
    Biol Psychiatry 69:1192-203. 2011
    ..The findings suggest overlapping but also distinct early cognitive effects of ADHD medications and have important implications for understanding the pathophysiology of ADHD and for future trials...
  16. doi request reprint Meta-analysis of the cognitive effects of the catechol-O-methyltransferase gene Val158/108Met polymorphism
    Jennifer H Barnett
    Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom
    Biol Psychiatry 64:137-44. 2008
    ..We conducted a meta-analysis of reported associations between the COMT Val158/108Met polymorphism and measures of memory and executive function...
  17. pmc A quantitative meta-analysis of population-based studies of premorbid intelligence and schizophrenia
    Golam M Khandaker
    Department of Psychiatry, University of Cambridge, Cambridge, UK
    Schizophr Res 132:220-7. 2011
    ....
  18. doi request reprint Adolescent self-organization predicts midlife memory in a prospective birth cohort study
    Man K Xu
    Department of Psychiatry, University of Cambridge
    Psychol Aging 28:958-68. 2013
    ..It has been suggested that interventions to improve self-organization may save a wide range of societal costs; this study also suggests that this might also benefit cognitive function in later life...
  19. pmc Reinforcement and reversal learning in first-episode psychosis
    G K Murray
    Brain Mapping Unit, Department of Psychiatry, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
    Schizophr Bull 34:848-55. 2008
    ..Abnormalities in reinforcement learning and reversal learning have been reported in psychosis, possibly secondary to subcortical dopamine abnormalities...
  20. ncbi request reprint Cognitive reserve in neuropsychiatry
    J H Barnett
    Department of Psychiatry, University of Cambridge School of Clinical Medicine, Addenbrooke s Hospital, Cambridge, UK
    Psychol Med 36:1053-64. 2006
    ..Here we suggest the hypothesis that cognitive reserve is also important in neuropsychiatric disorders including schizophrenia, bipolar disorder and depression...