Kay Barnes

Summary

Affiliation: University of Leeds
Country: UK

Publications

  1. ncbi request reprint Endothelin-converting enzyme: ultrastructural localization and its recycling from the cell surface
    K Barnes
    Department of Biochemistry and Molecular Biology, University of Leeds, UK
    Hypertension 31:3-9. 1998
  2. ncbi request reprint Chronic myeloid leukaemia: an investigation into the role of Bcr-Abl-induced abnormalities in glucose transport regulation
    Kay Barnes
    School of Biochemistry and Microbiology, University of Leeds, Leeds LS2 9JT, UK
    Oncogene 24:3257-67. 2005
  3. ncbi request reprint Distribution and functional characterization of equilibrative nucleoside transporter-4, a novel cardiac adenosine transporter activated at acidic pH
    Kay Barnes
    Institute of Membrane and Systems Biology, University of Leeds, UK
    Circ Res 99:510-9. 2006
  4. pmc Methyl-beta-cyclodextrin stimulates glucose uptake in Clone 9 cells: a possible role for lipid rafts
    Kay Barnes
    School of Biochemistry and Molecular Biology, University of Leeds, Leeds LS2 9JT, UK
    Biochem J 378:343-51. 2004
  5. ncbi request reprint Activation of GLUT1 by metabolic and osmotic stress: potential involvement of AMP-activated protein kinase (AMPK)
    Kay Barnes
    School of Biochemistry and Molecular Biology, University of Leeds, Leeds LS2 9JT, UK
    J Cell Sci 115:2433-42. 2002
  6. ncbi request reprint Interleukin-3-mediated cell survival signals include phosphatidylinositol 3-kinase-dependent translocation of the glucose transporter GLUT1 to the cell surface
    Johanne Bentley
    School of Biochemistry and Molecular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom
    J Biol Chem 278:39337-48. 2003
  7. ncbi request reprint Functional characterization of novel human and mouse equilibrative nucleoside transporters (hENT3 and mENT3) located in intracellular membranes
    Stephen A Baldwin
    School of Biochemistry and Microbiology, University of Leeds, Leeds LS2 9JT, United Kingdom
    J Biol Chem 280:15880-7. 2005
  8. ncbi request reprint Expression and localization of human endothelin-converting enzyme-1 isoforms in symptomatic atherosclerotic disease and saphenous vein
    Carolyn D Jackson
    School of Biochemistry and Microbiology, University of Leeds, Leeds LS29JT, United Kingdom
    Exp Biol Med (Maywood) 231:794-801. 2006
  9. ncbi request reprint Increased expression of endothelin-converting enzyme-1c isoform in response to high glucose levels in endothelial cells
    Shoshana Keynan
    Diabetes Center and Department of Internal Medicine, Hadassah University Hospital, Jerusalem, Israel
    J Vasc Res 41:131-40. 2004
  10. pmc Characterization of the role of the AMP-activated protein kinase in the stimulation of glucose transport in skeletal muscle cells
    Lee G D Fryer
    Cellular Stress Group, MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital, DuCane Road London, W12 0NN, UK
    Biochem J 363:167-74. 2002

Collaborators

Detail Information

Publications12

  1. ncbi request reprint Endothelin-converting enzyme: ultrastructural localization and its recycling from the cell surface
    K Barnes
    Department of Biochemistry and Molecular Biology, University of Leeds, UK
    Hypertension 31:3-9. 1998
    ..After treatment of endothelial cells with chloroquine, ECE and trans-Golgi network 38 protein were shown by immunofluorescence staining to localize to the same intracellular compartment...
  2. ncbi request reprint Chronic myeloid leukaemia: an investigation into the role of Bcr-Abl-induced abnormalities in glucose transport regulation
    Kay Barnes
    School of Biochemistry and Microbiology, University of Leeds, Leeds LS2 9JT, UK
    Oncogene 24:3257-67. 2005
    ....
  3. ncbi request reprint Distribution and functional characterization of equilibrative nucleoside transporter-4, a novel cardiac adenosine transporter activated at acidic pH
    Kay Barnes
    Institute of Membrane and Systems Biology, University of Leeds, UK
    Circ Res 99:510-9. 2006
    ..We hypothesize that ENT4, in addition to playing roles in cardiac serotonin transport, contributes to the regulation of extracellular adenosine concentrations, in particular under the acidotic conditions associated with ischemia...
  4. pmc Methyl-beta-cyclodextrin stimulates glucose uptake in Clone 9 cells: a possible role for lipid rafts
    Kay Barnes
    School of Biochemistry and Molecular Biology, University of Leeds, Leeds LS2 9JT, UK
    Biochem J 378:343-51. 2004
    ....
  5. ncbi request reprint Activation of GLUT1 by metabolic and osmotic stress: potential involvement of AMP-activated protein kinase (AMPK)
    Kay Barnes
    School of Biochemistry and Molecular Biology, University of Leeds, Leeds LS2 9JT, UK
    J Cell Sci 115:2433-42. 2002
    ..These enzymes, which have been implicated in stress-regulated pathways in other cell types, are therefore unlikely to play a role in transport regulation by stress in Clone 9 cells...
  6. ncbi request reprint Interleukin-3-mediated cell survival signals include phosphatidylinositol 3-kinase-dependent translocation of the glucose transporter GLUT1 to the cell surface
    Johanne Bentley
    School of Biochemistry and Molecular Biology, University of Leeds, Leeds LS2 9JT, United Kingdom
    J Biol Chem 278:39337-48. 2003
    ..We conclude that one component of the survival mechanisms elicited by IL-3 involves the subcellular redistribution of glucose transporters, thus ensuring the supply of a key metabolic substrate...
  7. ncbi request reprint Functional characterization of novel human and mouse equilibrative nucleoside transporters (hENT3 and mENT3) located in intracellular membranes
    Stephen A Baldwin
    School of Biochemistry and Microbiology, University of Leeds, Leeds LS2 9JT, United Kingdom
    J Biol Chem 280:15880-7. 2005
    ..However, it was strongly dependent upon pH, and the optimum pH value of 5.5 probably reflected the location of the transporter in acidic, intracellular compartments...
  8. ncbi request reprint Expression and localization of human endothelin-converting enzyme-1 isoforms in symptomatic atherosclerotic disease and saphenous vein
    Carolyn D Jackson
    School of Biochemistry and Microbiology, University of Leeds, Leeds LS29JT, United Kingdom
    Exp Biol Med (Maywood) 231:794-801. 2006
    ..Correlation of these isoform expression patterns with the stage of atherosclerosis could provide novel indicators of disease progression...
  9. ncbi request reprint Increased expression of endothelin-converting enzyme-1c isoform in response to high glucose levels in endothelial cells
    Shoshana Keynan
    Diabetes Center and Department of Internal Medicine, Hadassah University Hospital, Jerusalem, Israel
    J Vasc Res 41:131-40. 2004
    ..The main isoform to increase in response to high glucose was ECE-1c. This enzyme may be one of the factors contributing to the elevated ET-1 peptide levels observed in diabetes...
  10. pmc Characterization of the role of the AMP-activated protein kinase in the stimulation of glucose transport in skeletal muscle cells
    Lee G D Fryer
    Cellular Stress Group, MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital, DuCane Road London, W12 0NN, UK
    Biochem J 363:167-74. 2002
    ..Our results add further support to the hypothesis that long-term activation of AMPK is involved in the adaptive response of muscle to exercise training...
  11. ncbi request reprint Polarized distribution of nucleoside transporters in rat brain endothelial and choroid plexus epithelial cells
    Zoran B Redzic
    Department of Pharmacology, University of Cambridge, UK
    J Neurochem 94:1420-6. 2005
    ..In both RBEC and RCPEC, adenosine uptake from the opposite chambers was Na+-independent and partially inhibited by nitrobenzylthioinosine, indicating the presence of the equilibrative sensitive transporter rENT1...
  12. ncbi request reprint Quantitative proteomics reveals posttranslational control as a regulatory factor in primary hematopoietic stem cells
    Richard D Unwin
    Stem Cell and Leukaemia Proteomics Laboratory, Faculty of Medical and Human Sciences, University of Manchester, Manchester M20 4QL, UK
    Blood 107:4687-94. 2006
    ..This approach can define proteomic changes in primary samples, thereby characterizing the molecular signature of stem cells and their progeny...