Research Topics
| Francois BallouxSummaryAffiliation: University of Cambridge Country: UK Publications
| Collaborators |
Detail Information
Publications
The population genetics of clonal and partially clonal diploidsFrancois Balloux
I C A P B, University of Edinburgh, Edinburgh EH9 3JT, Scotland, United Kingdom
Genetics 164:1635-44. 2003....
Random mating with a finite number of matingsFrancois Balloux
Department of Genetics, University of Cambridge, Cambridge CB2 3EH, United Kingdom
Genetics 165:2313-5. 2003..This is obviously unrealistic. Here we show that when each female mates a finite number of times, the effective size of the population is substantially decreased...
Heterozygote excess in small populations and the heterozygote-excess effective population sizeFrancois Balloux
Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom
Evolution 58:1891-900. 2004..Applications to simulated data suggest the estimation of the number of breeders to be robust to mutation and migration rates, and to specificities of the mating system...
Distance from Africa, not climate, explains within-population phenotypic diversity in humansLia Betti
Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
Proc Biol Sci 276:809-14. 2009..These results mirror those previously obtained for genetic markers and show that 'bones and molecules' are in perfect agreement for humans...
Signatures of historical demography and pathogen richness on MHC class I genesNouar Qutob
Department of Zoology, University of Cambridge, Downing Street, Cambridge, CB2 3EJ, UK
Immunogenetics 64:165-75. 2012..This suggests that this residue, which is also involved in the binding of KIR, might have had an important evolutionary role that has been overlooked...
Going the distance: human population genetics in a clinal worldLori J Lawson Handley
Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, UK
Trends Genet 23:432-9. 2007..We also review recent technical advances and address the challenges of integrating geography and genetics...
The population genomics of hepatitis B virusCamille Szmaragd
Department of Genetics, University of Cambridge, Cambridge CB2 3EH, UK, and Institute for Animal Health, Ash Road, Pirbright, Surrey GU24 0NF, UK
Mol Ecol 16:4747-58. 2007..The extremely clear-cut subdivision of the HBV population further indicates that recombination in HBV is not as extensive as previously assumed...
Pathogen-driven selection and worldwide HLA class I diversityFranck Prugnolle
Theoretical and Molecular Population Genetics Group, Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom
Curr Biol 15:1022-7. 2005..This is in good agreement with both previous immunological and genetic data suggesting that HLA B could be under a higher selective pressure from pathogens...
The effect of ancient population bottlenecks on human phenotypic variationAndrea Manica
Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
Nature 448:346-8. 2007..Distance from Africa accounts for an average 19-25% of heritable variation in craniometric measurements-a remarkably strong effect for phenotypic measurements known to be under selection...
Population genetics of complex life-cycle parasites: an illustration with trematodesFranck Prugnolle
Theoretical and Molecular Population Genetics Group, Department of Genetics, Cambridge CB2 3EH, England
Int J Parasitol 35:255-63. 2005..We hope that our model will encourage more empirical population genetics studies on monoecious trematodes and other organisms with similar life-cycles...
Natural selection on fecundity variance in subdivided populations: kin selection meets bet hedgingLaurent Lehmann
Department of Genetics, University of Cambridge, CB2 3EH Cambridge, United Kingdom
Genetics 176:361-77. 2007..The evolutionary dynamics of all three traits are markedly affected by variance in offspring number, although to a different extent and under different demographic conditions...
A novel approach to characterise pathogen candidate genetic polymorphisms involved in clinical outcomeCamille Szmaragd
Theoretical and Molecular Population Genetics Group, Department of Genetics, University of Cambridge, Cambridge CB2 3EH, UK
Infect Genet Evol 6:38-45. 2006....
[Helicobacter pylori, our faithful gastric companion]Francois Balloux
Department of Genetics, University of Cambridge, Downing Street, Cambridge, UK
Med Sci (Paris) 23:705-6. 2007
