Francois Balloux

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi Heterozygote excess in small populations and the heterozygote-excess effective population size
    Francois Balloux
    Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom
    Evolution 58:1891-900. 2004
  2. pmc The population genetics of clonal and partially clonal diploids
    Francois Balloux
    I C A P B, University of Edinburgh, Edinburgh EH9 3JT, Scotland, United Kingdom
    Genetics 164:1635-44. 2003
  3. pmc Random mating with a finite number of matings
    Francois Balloux
    Department of Genetics, University of Cambridge, Cambridge CB2 3EH, United Kingdom
    Genetics 165:2313-5. 2003
  4. pmc A geographically explicit genetic model of worldwide human-settlement history
    Hua Liu
    Theoretical and Molecular Population Genetics Group, Department of Genetics, University of Cambridge, Cambridge, United Kingdom
    Am J Hum Genet 79:230-7. 2006
  5. pmc Geography predicts neutral genetic diversity of human populations
    Franck Prugnolle
    Theoretical and Molecular Population Genetics Group, Department of Genetics, University of Cambridge, Downing St, Cambridge CB2 3EH, UK
    Curr Biol 15:R159-60. 2005
  6. pmc Distance from Africa, not climate, explains within-population phenotypic diversity in humans
    Lia Betti
    Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
    Proc Biol Sci 276:809-14. 2009
  7. doi Signatures of historical demography and pathogen richness on MHC class I genes
    Nouar Qutob
    Department of Zoology, University of Cambridge, Downing Street, Cambridge, CB2 3EJ, UK
    Immunogenetics 64:165-75. 2012
  8. ncbi The population genomics of hepatitis B virus
    Camille Szmaragd
    Department of Genetics, University of Cambridge, Cambridge CB2 3EH, UK, and Institute for Animal Health, Ash Road, Pirbright, Surrey GU24 0NF, UK
    Mol Ecol 16:4747-58. 2007
  9. ncbi Going the distance: human population genetics in a clinal world
    Lori J Lawson Handley
    Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, UK
    Trends Genet 23:432-9. 2007
  10. pmc Geography is a better determinant of human genetic differentiation than ethnicity
    Andrea Manica
    Evolutionary Ecology Group, Department of Zoology, University of Cambridge, Downing Street, CB2 3EJ, Cambridge, UK
    Hum Genet 118:366-71. 2005

Detail Information

Publications18

  1. ncbi Heterozygote excess in small populations and the heterozygote-excess effective population size
    Francois Balloux
    Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom
    Evolution 58:1891-900. 2004
    ..Applications to simulated data suggest the estimation of the number of breeders to be robust to mutation and migration rates, and to specificities of the mating system...
  2. pmc The population genetics of clonal and partially clonal diploids
    Francois Balloux
    I C A P B, University of Edinburgh, Edinburgh EH9 3JT, Scotland, United Kingdom
    Genetics 164:1635-44. 2003
    ....
  3. pmc Random mating with a finite number of matings
    Francois Balloux
    Department of Genetics, University of Cambridge, Cambridge CB2 3EH, United Kingdom
    Genetics 165:2313-5. 2003
    ..This is obviously unrealistic. Here we show that when each female mates a finite number of times, the effective size of the population is substantially decreased...
  4. pmc A geographically explicit genetic model of worldwide human-settlement history
    Hua Liu
    Theoretical and Molecular Population Genetics Group, Department of Genetics, University of Cambridge, Cambridge, United Kingdom
    Am J Hum Genet 79:230-7. 2006
    ..The general fit of the model with the data is excellent. This suggests that coupling analytical genetic models with explicit demography and geography provides a powerful tool for making inferences on human-settlement history...
  5. pmc Geography predicts neutral genetic diversity of human populations
    Franck Prugnolle
    Theoretical and Molecular Population Genetics Group, Department of Genetics, University of Cambridge, Downing St, Cambridge CB2 3EH, UK
    Curr Biol 15:R159-60. 2005
  6. pmc Distance from Africa, not climate, explains within-population phenotypic diversity in humans
    Lia Betti
    Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
    Proc Biol Sci 276:809-14. 2009
    ..These results mirror those previously obtained for genetic markers and show that 'bones and molecules' are in perfect agreement for humans...
  7. doi Signatures of historical demography and pathogen richness on MHC class I genes
    Nouar Qutob
    Department of Zoology, University of Cambridge, Downing Street, Cambridge, CB2 3EJ, UK
    Immunogenetics 64:165-75. 2012
    ..This suggests that this residue, which is also involved in the binding of KIR, might have had an important evolutionary role that has been overlooked...
  8. ncbi The population genomics of hepatitis B virus
    Camille Szmaragd
    Department of Genetics, University of Cambridge, Cambridge CB2 3EH, UK, and Institute for Animal Health, Ash Road, Pirbright, Surrey GU24 0NF, UK
    Mol Ecol 16:4747-58. 2007
    ..The extremely clear-cut subdivision of the HBV population further indicates that recombination in HBV is not as extensive as previously assumed...
  9. ncbi Going the distance: human population genetics in a clinal world
    Lori J Lawson Handley
    Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, UK
    Trends Genet 23:432-9. 2007
    ..We also review recent technical advances and address the challenges of integrating geography and genetics...
  10. pmc Geography is a better determinant of human genetic differentiation than ethnicity
    Andrea Manica
    Evolutionary Ecology Group, Department of Zoology, University of Cambridge, Downing Street, CB2 3EJ, Cambridge, UK
    Hum Genet 118:366-71. 2005
    ..We conclude that the use of ethnicity alone will often be inadequate as a basis for medical treatment...
  11. pmc The effect of ancient population bottlenecks on human phenotypic variation
    Andrea Manica
    Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
    Nature 448:346-8. 2007
    ..Distance from Africa accounts for an average 19-25% of heritable variation in craniometric measurements-a remarkably strong effect for phenotypic measurements known to be under selection...
  12. pmc Natural selection on fecundity variance in subdivided populations: kin selection meets bet hedging
    Laurent Lehmann
    Department of Genetics, University of Cambridge, CB2 3EH Cambridge, United Kingdom
    Genetics 176:361-77. 2007
    ..The evolutionary dynamics of all three traits are markedly affected by variance in offspring number, although to a different extent and under different demographic conditions...
  13. ncbi Pathogen-driven selection and worldwide HLA class I diversity
    Franck Prugnolle
    Theoretical and Molecular Population Genetics Group, Department of Genetics, University of Cambridge, Downing Street, Cambridge CB2 3EH, United Kingdom
    Curr Biol 15:1022-7. 2005
    ..This is in good agreement with both previous immunological and genetic data suggesting that HLA B could be under a higher selective pressure from pathogens...
  14. ncbi Population genetics of complex life-cycle parasites: an illustration with trematodes
    Franck Prugnolle
    Theoretical and Molecular Population Genetics Group, Department of Genetics, Cambridge CB2 3EH, England
    Int J Parasitol 35:255-63. 2005
    ..We hope that our model will encourage more empirical population genetics studies on monoecious trematodes and other organisms with similar life-cycles...
  15. ncbi A novel approach to characterise pathogen candidate genetic polymorphisms involved in clinical outcome
    Camille Szmaragd
    Theoretical and Molecular Population Genetics Group, Department of Genetics, University of Cambridge, Cambridge CB2 3EH, UK
    Infect Genet Evol 6:38-45. 2006
    ....
  16. pmc Rates of vaccine evolution show strong effects of latency: implications for varicella zoster virus epidemiology
    Lucy A Weinert
    Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom Department of Genetics, Evolution and Environment, UCL, London, United Kingdom
    Mol Biol Evol 32:1020-8. 2015
    ..Nevertheless, we show that implausibly long latency periods are required to date the most recent common ancestor of extant VZV to an "out-of-Africa" migration with humans, as has been previously suggested. ..
  17. pmc Improved calibration of the human mitochondrial clock using ancient genomes
    Adrien Rieux
    UCL Genetics Institute, Department of Genetics, Evolution and Environment, University College London, London, United Kingdom
    Mol Biol Evol 31:2780-92. 2014
    ..Our results demonstrate that, for the same data set, estimates based on individual dated tips are far more consistent with each other than those based on nodes and should thus be considered as more reliable. ..
  18. ncbi [Helicobacter pylori, our faithful gastric companion]
    Francois Balloux
    Department of Genetics, University of Cambridge, Downing Street, Cambridge, UK
    Med Sci (Paris) 23:705-6. 2007