T Baldeweg

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi Nicotinic modulation of human auditory sensory memory: Evidence from mismatch negativity potentials
    Torsten Baldeweg
    Institute of Child Health and Great Ormond Street Hospital, 30 Guilford Street, London WC1N 1EH, UK
    Int J Psychophysiol 59:49-58. 2006
  2. ncbi Differential changes in frontal and sub-temporal components of mismatch negativity
    T Baldeweg
    Division of Neuroscience and Psychological Medicine, Imperial College School of Medicine, Charing Cross Hospital, London, UK
    Int J Psychophysiol 33:143-8. 1999
  3. ncbi Impairment in frontal but not temporal components of mismatch negativity in schizophrenia
    Torsten Baldeweg
    Institute of Child Health and Great Ormond Street Hospital, Wolfson Centre, Mecklenburgh Square, WC1N 2AP, London, UK
    Int J Psychophysiol 43:111-22. 2002
  4. ncbi Detecting white matter injury in sickle cell disease using voxel-based morphometry
    Torsten Baldeweg
    Developmental Cognitive Neuroscience Unit, Institute of Child Health, University College, London, United Kingdom
    Ann Neurol 59:662-72. 2006
  5. ncbi Mismatch negativity potentials and cognitive impairment in schizophrenia
    Torsten Baldeweg
    Institute of Child Health and Great Ormond Street Hospital, Wolfson Centre, Mecklenburgh Square, London WC1N 2AP, UK
    Schizophr Res 69:203-17. 2004
  6. ncbi Electrophysiological evidence of serotonergic impairment in long-term MDMA ("ecstasy") users
    R J Croft
    Department of Cognitive Neuroscience and Behavior, Imperial College, School of Medicine, London, UK
    Am J Psychiatry 158:1687-92. 2001
  7. ncbi A role for sleep disruption in cognitive impairment in children with epilepsy
    S Chan
    Neurosciences Unit, UCL Institute of Child Health, London, UK
    Epilepsy Behav 20:435-40. 2011
  8. ncbi Hypnosis and event-related potential correlates of error processing in a stroop-type paradigm: a test of the frontal hypothesis
    J Kaiser
    Department of Psychology and Cognitive Neuroscience, Imperial School of Medicine, London, UK
    Int J Psychophysiol 27:215-22. 1997
  9. ncbi Gamma and beta frequency oscillations in response to novel auditory stimuli: A comparison of human electroencephalogram (EEG) data with in vitro models
    C Haenschel
    Division of Neuroscience and Psychological Medicine, Imperial College School of Medicine, London W6 8RP, United Kingdom
    Proc Natl Acad Sci U S A 97:7645-50. 2000
  10. ncbi Human memory development and its dysfunction after early hippocampal injury
    Michelle de Haan
    Developmental Cognitive Neuroscience Unit, University College London Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Trends Neurosci 29:374-81. 2006

Collaborators

Detail Information

Publications34

  1. ncbi Nicotinic modulation of human auditory sensory memory: Evidence from mismatch negativity potentials
    Torsten Baldeweg
    Institute of Child Health and Great Ormond Street Hospital, 30 Guilford Street, London WC1N 1EH, UK
    Int J Psychophysiol 59:49-58. 2006
    ..These results have potential implications for schizophrenia by suggesting that nicotinic agonists could ameliorate patients' MMN deficits by improving stimulus encoding and sensory memory trace formation...
  2. ncbi Differential changes in frontal and sub-temporal components of mismatch negativity
    T Baldeweg
    Division of Neuroscience and Psychological Medicine, Imperial College School of Medicine, Charing Cross Hospital, London, UK
    Int J Psychophysiol 33:143-8. 1999
    ..This suggests that more than one generator underpins the two mismatch components, and that the sub-temporal mismatch component does not only represent a polarity reversal of the main MMN component in the superior temporal gyrus...
  3. ncbi Impairment in frontal but not temporal components of mismatch negativity in schizophrenia
    Torsten Baldeweg
    Institute of Child Health and Great Ormond Street Hospital, Wolfson Centre, Mecklenburgh Square, WC1N 2AP, London, UK
    Int J Psychophysiol 43:111-22. 2002
    ..This finding raises the possibility of a selective impairment in multiple mismatch generators in schizophrenia and may lend support for the notion of impaired cortico-cortical connectivity in schizophrenia...
  4. ncbi Detecting white matter injury in sickle cell disease using voxel-based morphometry
    Torsten Baldeweg
    Developmental Cognitive Neuroscience Unit, Institute of Child Health, University College, London, United Kingdom
    Ann Neurol 59:662-72. 2006
    ..This study aimed to detect the presence and extent of white matter abnormalities in individuals with SCD using voxel-based morphometry (VBM)...
  5. ncbi Mismatch negativity potentials and cognitive impairment in schizophrenia
    Torsten Baldeweg
    Institute of Child Health and Great Ormond Street Hospital, Wolfson Centre, Mecklenburgh Square, London WC1N 2AP, UK
    Schizophr Res 69:203-17. 2004
    ..This suggests that ERP measures of auditory system adaptability more appropriately characterise the pathophysiological processes underlying cognitive impairment in schizophrenia than static measures of ERP magnitude...
  6. ncbi Electrophysiological evidence of serotonergic impairment in long-term MDMA ("ecstasy") users
    R J Croft
    Department of Cognitive Neuroscience and Behavior, Imperial College, School of Medicine, London, UK
    Am J Psychiatry 158:1687-92. 2001
    ..The results are thus consistent with the thesis that MDMA consumption causes 5-HT impairment in humans...
  7. ncbi A role for sleep disruption in cognitive impairment in children with epilepsy
    S Chan
    Neurosciences Unit, UCL Institute of Child Health, London, UK
    Epilepsy Behav 20:435-40. 2011
    ..In this review we present clinical and experimental evidence that suggests that the disruption of sleep architecture by epileptiform discharges may be an important factor contributing to cognitive impairment in children with epilepsy...
  8. ncbi Hypnosis and event-related potential correlates of error processing in a stroop-type paradigm: a test of the frontal hypothesis
    J Kaiser
    Department of Psychology and Cognitive Neuroscience, Imperial School of Medicine, London, UK
    Int J Psychophysiol 27:215-22. 1997
    ..The results with hypnosis are interpreted as a failure of context updating without a global deficit in supervisory attention...
  9. ncbi Gamma and beta frequency oscillations in response to novel auditory stimuli: A comparison of human electroencephalogram (EEG) data with in vitro models
    C Haenschel
    Division of Neuroscience and Psychological Medicine, Imperial College School of Medicine, London W6 8RP, United Kingdom
    Proc Natl Acad Sci U S A 97:7645-50. 2000
    ..A further analogy between in vitro and human recordings was that both gamma and beta oscillations habituated markedly after the initial novel stimulus presentation...
  10. ncbi Human memory development and its dysfunction after early hippocampal injury
    Michelle de Haan
    Developmental Cognitive Neuroscience Unit, University College London Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Trends Neurosci 29:374-81. 2006
    ..This review is part of the INMED/TINS special issue "Nature and nurture in brain development and neurological disorders", based on presentations at the annual INMED/TINS symposium (http://inmednet.com/)...
  11. ncbi The development of intellectual abilities in pediatric temporal lobe epilepsy
    Francesca Cormack
    Developmental Cognitive Neuroscience Unit, Institute of Child Health, University College London, London, UK
    Epilepsia 48:201-4. 2007
    ..The aim of this study was to examine the impact of clinical variables, particularly age at onset of epilepsy, on intellectual function in a group of children with temporal lobe epilepsy (TLE)...
  12. ncbi Speaking with a single cerebral hemisphere: fMRI language organization after hemispherectomy in childhood
    Frédérique Liégeois
    Developmental Cognitive Neuroscience Unit, UCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Brain Lang 106:195-203. 2008
    ..The results suggest that distinct subregions of Broca's area and their right homologs can subserve speech and language, and that this variability may determine functional outcome...
  13. ncbi Development of aptitude at altitude
    Alexandra M Hogan
    UCL Institute of Child Health, London, UK
    Dev Sci 13:533-44. 2010
    ..Thus, psychomotor slowing is proposed to be an adaptive rather than a deficient trait, perhaps enabling accuracy of mental activity in hypoxic conditions...
  14. ncbi Extra-hippocampal grey matter density abnormalities in paediatric mesial temporal sclerosis
    Francesca Cormack
    Developmental Cognitive Neuroscience Unit, Institute of Child Health, University College London, London WC1N 1EH, UK
    Neuroimage 27:635-43. 2005
    ....
  15. ncbi COMT Val108/158 Met modifies mismatch negativity and cognitive function in 22q11 deletion syndrome
    Kate Baker
    Behavioural and Brain Sciences Unit, Institute of Child Health, University College London, London, United Kingdom
    Biol Psychiatry 58:23-31. 2005
    ..We further predicted that the catechol-O-methyltransferase Val(108/158)Met polymorphism, located within the deleted chromosomal segment, would modify the severity of endophenotypic features...
  16. ncbi Language fMRI abnormalities associated with FOXP2 gene mutation
    Frédérique Liégeois
    Developmental Cognitive Neuroscience Unit, Institute of Child Health, University College London, The Wolfson Centre, Mecklenburgh Square, London WC1N 2AP, UK
    Nat Neurosci 6:1230-7. 2003
    ..Our findings suggest that the FOXP2 gene is critically involved in the development of the neural systems that mediate speech and language...
  17. ncbi Neocortical and hippocampal volume loss in a human ciliopathy: A quantitative MRI study in Bardet-Biedl syndrome
    Kate Baker
    UCL Institute of Child Health, London, UK
    Am J Med Genet A 155:1-8. 2011
    ..These findings are consistent with previous observations in mouse models of BBS, and further implicate the cilium in neurodevelopmental processes relevant to human cognitive function...
  18. ncbi Synaptic plasticity and dysconnection in schizophrenia
    Klaas E Stephan
    Wellcome Department of Imaging Neuroscience, Institute of Neurology, University College London, London, United Kingdom
    Biol Psychiatry 59:929-39. 2006
    ..Promising experimental paradigms include perceptual and reinforcement learning. We describe how theoretical and causal models of brain responses might contribute to a mechanistic understanding of synaptic plasticity in schizophrenia...
  19. ncbi Long-term intellectual outcome after temporal lobe surgery in childhood
    C Skirrow
    Developmental Cognitive Neuroscience Unit, Institute of Child Health, University College London, London WC1N 1EH, UK
    Neurology 76:1330-7. 2011
    ..The aim of this study was to characterize intellectual and psychosocial functioning of children after temporal lobe resection as they progress into late adolescence and adulthood...
  20. ncbi Heterogeneity in the patterns of neural abnormality in autistic spectrum disorders: evidence from ERP and MRI
    Claire H Salmond
    Developmental Cognitive Neuroscience Unit, Institute of Child Health, University College London, London, UK
    Cortex 43:686-99. 2007
    ..These data provide convergent ERP and MRI evidence for the heterogeneity of neural abnormality in ASD in relation to variations in intelligence...
  21. ncbi Impact of frontal white matter lesions on performance monitoring: ERP evidence for cortical disconnection
    Alexandra M Hogan
    Developmental Cognitive Neuroscience Unit, Institute of Child Health, University College London, Great Ormond Street Hospital for Children NHS Trust, London, UK
    Brain 129:2177-88. 2006
    ....
  22. ncbi Cortical lateralization during verb generation: a combined ERP and fMRI study
    Alison Rowan
    Developmental Cognitive Neuroscience Unit, Institute of Child Health, University College London, London, WC1N 1EH, UK
    Neuroimage 22:665-75. 2004
    ..Thus, ERPs and fMRI provided convergent evidence regarding language lateralization, with ERPs revealing the temporal sequence of posterior to anterior cortical activation during semantic retrieval...
  23. ncbi Maturation of action monitoring from adolescence to adulthood: an ERP study
    Alexandra M Hogan
    Developmental Cognitive Neuroscience Unit, Institute of Child Health, University College London, UK
    Dev Sci 8:525-34. 2005
    ..In conclusion, the neural systems underlying action-monitoring continue to mature throughout the second decade of life, and are associated with increased efficiency for fast error detection and correction during complex tasks...
  24. ncbi Language reorganization in children with early-onset lesions of the left hemisphere: an fMRI study
    F Liegeois
    Developmental Cognitive Neuroscience Unit, Institute of Child Health, UCL, 4th Floor, 30 Guilford Street, London WC1N 1EH, UK
    Brain 127:1229-36. 2004
    ..In conclusion, it is difficult to infer intra- versus inter-hemispheric language reorganization on the basis of clinical observations in the presence of early pathology to the left hemisphere...
  25. ncbi A direct test for lateralization of language activation using fMRI: comparison with invasive assessments in children with epilepsy
    F Liegeois
    Developmental Cognitive Neuroscience Unit, Institute of Child Health, University College London, Great Ormond Street Hospital for Children NHS Trust, London, WC1N 2AP, United Kingdom
    Neuroimage 17:1861-7. 2002
    ..It is suggested that the direct method could be used in future fMRI studies to establish hemispheric lateralization for cognitive functions...
  26. ncbi Cortical abnormalities and language function in young patients with basal ganglia stroke
    Alison Rowan
    Developmental Cognitive Neuroscience Unit, UCL Institute of Child Health, London WClN 1EH, UK
    Neuroimage 36:431-40. 2007
    ..We suggest that language impairments following basal ganglia damage may be attributable primarily to abnormalities in cortical language areas that are too subtle to detect on conventional structural MRI...
  27. ncbi Hippocampal atrophy in temporal lobe epilepsy is correlated with limbic systems atrophy
    Emrah Duzel
    Department of Neurology II, Otto von Guericke University Magdeburg, Leipziger Str 44, 39120 Magdeburg, Germany
    J Neurol 253:294-300. 2006
    ....
  28. ncbi Interhemispheric differences of spectral power in expressive language: a MEG study with clinical applications
    Alison Eleanor Fisher
    Neuroscience Research, School of Life and Health Sciences, Aston University, Birmingham, B4 7ET, United Kingdom
    Int J Psychophysiol 68:111-22. 2008
    ..Furthermore, our findings highlight the potential utility of MEG for the investigation of cortical language functioning in both healthy development and pathology...
  29. ncbi Mismatch negativity in schizophrenia: a family study
    Elvira Bramon
    Institute of Psychiatry, PO Box 63, De Crespigny Park, Denmark Hill, London SE5 8AF, UK
    Schizophr Res 67:1-10. 2004
    ..We investigated whether MMN is a potential marker of genetic vulnerability to schizophrenia by comparing MMN in a group of patients with schizophrenia, their unaffected relatives, and controls...
  30. ncbi Acute dopamine D(1) and D(2) receptor stimulation does not modulate mismatch negativity (MMN) in healthy human subjects
    Sumie Leung
    Biological Psychiatry Research Unit, Brain Sciences Institute, Faculty of Life and Social Sciences, Swinburne University of Technology, Melbourne, Australia
    Psychopharmacology (Berl) 194:443-51. 2007
    ....
  31. ncbi Event-related brain potential correlates of human auditory sensory memory-trace formation
    Corinna Haenschel
    Department of Psychiatry, Johann Wolfgang Goethe University, 60590 Frankfurt, Germany
    J Neurosci 25:10494-501. 2005
    ..RP may represent a human ERP correlate of rapid and stimulus-specific adaptation, a candidate neuronal mechanism underlying sensory memory formation in the auditory cortex...
  32. ncbi The source of afterdischarge activity in neocortical tonic-clonic epilepsy
    Andrew J Trevelyan
    School of Neurology, Neurobiology and Psychiatry, Medical School, University of Newcastle, Newcastle upon Tyne NE2 4HH, United Kingdom
    J Neurosci 27:13513-9. 2007
    ..Our data suggest a complex view of seizures in which the ictal event and its constituent discharges originate from distinct locations...
  33. ncbi Repetition effects to sounds: evidence for predictive coding in the auditory system
    Torsten Baldeweg
    Trends Cogn Sci 10:93-4. 2006
  34. ncbi Axonal gap junctions between principal neurons: a novel source of network oscillations, and perhaps epileptogenesis
    Roger D Traub
    Department of Physiology, SUNY Downstate Medical Center, Brooklyn 11203, USA
    Rev Neurosci 13:1-30. 2002
    ....