S P Balasubramanian

Summary

Affiliation: University of Sheffield
Country: UK

Publications

  1. ncbi request reprint Association of a common variant of the CASP8 gene with reduced risk of breast cancer
    Gordon MacPherson
    Division of Genomic Medicine, University of Sheffield Medical School, Sheffield, UK
    J Natl Cancer Inst 96:1866-9. 2004
  2. pmc Standards of reporting of randomized controlled trials in general surgery: can we do better?
    Sabapathy P Balasubramanian
    Academic Unit of Surgical Oncology, K Floor, Royal Hallamshire Hospital, University of Sheffield, S10 2JF, UK
    Ann Surg 244:663-7. 2006
  3. doi request reprint Sentinel node biopsy in papillary thyroid cancer-what is the potential?
    S P Balasubramanian
    Department of Oncology, University of Sheffield, Sheffield, UK
    Langenbecks Arch Surg 399:245-51. 2014
  4. pmc Endostatin gene variation and protein levels in breast cancer susceptibility and severity
    Sabapathy P Balasubramanian
    Academic Surgical Oncology Unit, University of Sheffield, Sheffield, UK
    BMC Cancer 7:107. 2007
  5. pmc Interleukin gene polymorphisms and breast cancer: a case control study and systematic literature review
    S P Balasubramanian
    Academic Surgical Oncology Unit, University of Sheffield, Sheffield, UK
    BMC Cancer 6:188. 2006
  6. ncbi request reprint Ischemic vascular disease and solid cancers: opposing ends of the angiogenic spectrum?
    S P Balasubramanian
    Academic Surgical Oncology Unit, University of Sheffield, K Floor, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, United Kingdom
    Med Hypotheses 67:1317-9. 2006
  7. doi request reprint Systematic review and meta-analysis of sentinel node biopsy in thyroid cancer
    S P Balasubramanian
    Academic Unit of Surgical Oncology, Department of Oncology, Royal Hallamshire Hospital, School of Medicine and Biomedical Sciences, University of Sheffield, Sheffield, UK
    Br J Surg 98:334-44. 2011
  8. pmc Angiogenesis is associated with the onset of hyperplasia in human ductal breast disease
    J E Bluff
    Microcirculation Research Group, Academic Unit of Surgical Oncology, University of Sheffield Medical School, Sheffield, South Yorkshire, UK
    Br J Cancer 101:666-72. 2009
  9. pmc Expression of receptor activator of nuclear factor kappabeta ligand (RANKL) and tumour necrosis factor related, apoptosis inducing ligand (TRAIL) in breast cancer, and their relations with osteoprotegerin, oestrogen receptor, and clinicopathological varia
    S S Cross
    Academic Unit of Pathology, School of Medicine and Biomedical Sciences, University of Sheffield, UK
    J Clin Pathol 59:716-20. 2006
  10. ncbi request reprint Candidate gene polymorphisms in solid cancers
    S P Balasubramanian
    Academic Unit of Surgical Oncology, K Floor, University of Sheffield, Royal Hallamshire Hospital, Sheffield S10 2JF, UK
    Eur J Surg Oncol 30:593-601. 2004

Detail Information

Publications24

  1. ncbi request reprint Association of a common variant of the CASP8 gene with reduced risk of breast cancer
    Gordon MacPherson
    Division of Genomic Medicine, University of Sheffield Medical School, Sheffield, UK
    J Natl Cancer Inst 96:1866-9. 2004
    ..0002, adjusted for study). The reproducible, dose-dependent association of CASP8 D302H with breast cancer indicates the potential importance of inherited variation in the apoptosis pathway in breast cancer susceptibility...
  2. pmc Standards of reporting of randomized controlled trials in general surgery: can we do better?
    Sabapathy P Balasubramanian
    Academic Unit of Surgical Oncology, K Floor, Royal Hallamshire Hospital, University of Sheffield, S10 2JF, UK
    Ann Surg 244:663-7. 2006
    ....
  3. doi request reprint Sentinel node biopsy in papillary thyroid cancer-what is the potential?
    S P Balasubramanian
    Department of Oncology, University of Sheffield, Sheffield, UK
    Langenbecks Arch Surg 399:245-51. 2014
    ....
  4. pmc Endostatin gene variation and protein levels in breast cancer susceptibility and severity
    Sabapathy P Balasubramanian
    Academic Surgical Oncology Unit, University of Sheffield, Sheffield, UK
    BMC Cancer 7:107. 2007
    ..Endostatin protein expression on a breast cancer micro array was also studied to determine any relationship to genotype and to breast cancer prognosis...
  5. pmc Interleukin gene polymorphisms and breast cancer: a case control study and systematic literature review
    S P Balasubramanian
    Academic Surgical Oncology Unit, University of Sheffield, Sheffield, UK
    BMC Cancer 6:188. 2006
    ..The aim of this study was to evaluate any role of specific SNPs in the interleukin genes IL1A, IL1B, IL1RN, IL4R, IL6 and IL10 in predisposition to breast cancer susceptibility and severity...
  6. ncbi request reprint Ischemic vascular disease and solid cancers: opposing ends of the angiogenic spectrum?
    S P Balasubramanian
    Academic Surgical Oncology Unit, University of Sheffield, K Floor, Royal Hallamshire Hospital, Glossop Road, Sheffield S10 2JF, United Kingdom
    Med Hypotheses 67:1317-9. 2006
    ..Modifying risk for patients at high risk of disease at the two opposing ends of the spectrum may then be possible by either lifestyle or dietary alterations or drugs targeting the angiogenic pathway...
  7. doi request reprint Systematic review and meta-analysis of sentinel node biopsy in thyroid cancer
    S P Balasubramanian
    Academic Unit of Surgical Oncology, Department of Oncology, Royal Hallamshire Hospital, School of Medicine and Biomedical Sciences, University of Sheffield, Sheffield, UK
    Br J Surg 98:334-44. 2011
    ..Several studies have investigated the role of SNB in thyroid cancer. This is a systematic review and meta-analysis of the role of SNB in the management of thyroid cancer...
  8. pmc Angiogenesis is associated with the onset of hyperplasia in human ductal breast disease
    J E Bluff
    Microcirculation Research Group, Academic Unit of Surgical Oncology, University of Sheffield Medical School, Sheffield, South Yorkshire, UK
    Br J Cancer 101:666-72. 2009
    ..The precise timing of the angiogenic switch and the role of angiogenesis in the development of breast malignancy is currently unknown...
  9. pmc Expression of receptor activator of nuclear factor kappabeta ligand (RANKL) and tumour necrosis factor related, apoptosis inducing ligand (TRAIL) in breast cancer, and their relations with osteoprotegerin, oestrogen receptor, and clinicopathological varia
    S S Cross
    Academic Unit of Pathology, School of Medicine and Biomedical Sciences, University of Sheffield, UK
    J Clin Pathol 59:716-20. 2006
    ..Their functions are linked by their interactions with osteoprotegerin (OPG)...
  10. ncbi request reprint Candidate gene polymorphisms in solid cancers
    S P Balasubramanian
    Academic Unit of Surgical Oncology, K Floor, University of Sheffield, Royal Hallamshire Hospital, Sheffield S10 2JF, UK
    Eur J Surg Oncol 30:593-601. 2004
    ..In this article, we illustrate the types of genetic variation and the complexities involved in their study and discuss their potential in predicting both the occurrence and outcomes of solid cancers...
  11. ncbi request reprint Osteoprotegerin (OPG)--a potential new role in the regulation of endothelial cell phenotype and tumour angiogenesis?
    Simon S Cross
    Academic Units of Clinical Oncology, Pathology and Surgical Oncology, School of Medicine and Biomedical Sciences, University of Sheffield, Sheffield, UK
    Int J Cancer 118:1901-8. 2006
    ..This is the first study to report the proangiogenic effects of OPG in vitro, as well as correlating expression of OPG by tumour endothelial cells with clinicopathological data in human tumours...
  12. ncbi request reprint Osteoprotegerin (OPG) expression by breast cancer cells in vitro and breast tumours in vivo--a role in tumour cell survival?
    Ingunn Holen
    Bone Oncology Group, Division of Genomic Medicine, University of Sheffield, Sheffield, UK
    Breast Cancer Res Treat 92:207-15. 2005
    ..To our knowledge these results are the first to demonstrate that OPG can act as an endocrine survival factor for breast cancer cells, as well as reporting the expression patterns of OPG in a large cohort of human breast tumours...
  13. doi request reprint Expression of beta-dystroglycan is reduced or absent in many human carcinomas
    S S Cross
    Academic Unit of Pathology, School of Medicine and Biomedical Sciences, University of Sheffield, Sheffield, UK
    Histopathology 53:561-6. 2008
    ..The aim was to conduct a comprehensive immunohistochemical survey of the expression of beta-dystroglycan in normal human tissues and common cancers...
  14. pmc Role of genetic polymorphisms in tumour angiogenesis
    S P Balasubramanian
    Academic Unit of Surgical Oncology, University of Sheffield, Sheffield S10 2JF, UK
    Br J Cancer 87:1057-65. 2002
    ..This article reviews the literature to determine the possible role of angiogenesis-related polymorphisms in cancer. Further research studies in this potentially crucial area of tumour biology are proposed...
  15. doi request reprint Primary hyperparathyroidism: an analysis of failure of parathyroidectomy
    A Bagul
    Royal Hallamshire Hospital, Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, UK
    World J Surg 38:534-41. 2014
    ..The aims of this study were to assess whether the findings on preoperative localisation influenced outcomes following parathyroidectomy for PHPT and to explore factors underlying failure to cure at surgery...
  16. ncbi request reprint Description and reporting of surgical data--scope for improvement?
    P M Robinson
    Academic Unit of Surgical Oncology, University of Sheffield
    Surgeon 7:6-9. 2009
    ..The aim of this study was to determine the appropriateness of descriptive methods (e.g. mean, median, SD, range) and survey the use of inferential methods (statistical tests) in key general surgical journals...
  17. ncbi request reprint Audit of compliance to adjuvant chemotherapy and radiotherapy guidelines in breast cancer in a cancer network
    S P Balasubramanian
    Surgical Oncology, K Floor, Royal Hallamshire Hospital, University of Sheffield, Sheffield S10 2JF, UK
    Breast 12:136-41. 2003
    ..We discuss the possible reasons for non-compliance and show a need to periodically monitor compliance to adjuvant treatment guidelines...
  18. doi request reprint Systematic review of intravenous methylene blue in parathyroid surgery
    H P Patel
    Department of Oncology, University of Sheffield, Chesterfield Royal Hospital NHS Foundation Trust, Sheffield, UK
    Br J Surg 99:1345-51. 2012
    ..The aim of this study was to perform a systematic review of the use of methylene blue in parathyroidectomy...
  19. ncbi request reprint Percutaneous biopsy of adrenal and extra-adrenal retroperitoneal lesions: beware of catecholamine secreting tumours!
    S K Sood
    Unit of Surgical Oncology, University of Sheffield, Sheffield
    Surgeon 5:279-81. 2007
    ..Approximately 5% of all incidentally detected adrenal lesions are phaeochromocytomas and 25% of phaeochromocytomas are discovered during imaging studies for unrelated disorders. 10% of phaeochromocytomas are extra-adrenal...
  20. ncbi request reprint Influence of VEGF-A gene variation and protein levels in breast cancer susceptibility and severity
    Sabapathy P Balasubramanian
    Academic Surgical Oncology Unit, University of Sheffield, Royal Hallamshire Hospital, Sheffield, England
    Int J Cancer 121:1009-16. 2007
    ..VEGF expression in breast cancers was however associated with high grade (p = 0.002) and ER negative tumours (p = 0.03)...
  21. pmc Heterogeneity of breast cancer associations with five susceptibility loci by clinical and pathological characteristics
    Montserrat Garcia-Closas
    Division of Cancer Epidemiology and Genetics, National Cancer Institute, Rockville, Marylan, United States of America
    PLoS Genet 4:e1000054. 2008
    ..Understanding the etiologic heterogeneity of breast cancer may ultimately result in improvements in prevention, early detection, and treatment...
  22. ncbi request reprint The CASP8 -652 6N del promoter polymorphism and breast cancer risk: a multicenter study
    Bernd Frank
    Helmholtz University Group Molecular Epidemiology, German Cancer Research Center, DKFZ, Im Neuenheimer Feld 581, 69120, Heidelberg, Germany
    Breast Cancer Res Treat 111:139-44. 2008
    ..The combined per allele odds ratio (OR) was 0.97 (95% confidence interval (CI), 95% CI = 0.93-1.02). The present result indicates that the CASP8 -652 6N del variant has no significant effect on BC risk in Europeans...
  23. ncbi request reprint Improving the quality of reporting randomized controlled trials in cardiothoracic surgery: the way forward
    Ravindranath Tiruvoipati
    Department of Cardiac Surgery and ECMO, Glenfield Hospital, Leicester, Leicester, United Kingdom
    J Thorac Cardiovasc Surg 132:233-40. 2006
    ....
  24. ncbi request reprint An observational study of cancers among female partners of UK-resident prostate cancer patients
    Narasimhan Ragavan
    Department of Biological Sciences, Lancaster University, Lancaster LA1 4YQ, UK
    Cancer Lett 242:88-94. 2006
    ..However, observed rates for breast or lung cancers among PFPs were significantly (P< or =0.001) elevated. Our results suggest no evidence of elevated risk among female partners of CaP males...