Dean A Baker

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. pmc Role of testis-specific gene expression in sex-chromosome evolution of Anopheles gambiae
    Dean A Baker
    Department of Genetics, University of Cambridge, Cambridge CB1 3QA, United Kingdom
    Genetics 189:1117-20. 2011
  2. pmc Variable sexually dimorphic gene expression in laboratory strains of Drosophila melanogaster
    Dean A Baker
    Department of Genetics, University of Cambridge, Downing Street, Cambridge CB1 3QA, UK
    BMC Genomics 8:454. 2007
  3. pmc Gene expression during Drosophila melanogaster egg development before and after reproductive diapause
    Dean A Baker
    Department of Genetics, University of Cambridge, Downing Street, Cambridge CB13QA, UK
    BMC Genomics 10:242. 2009
  4. pmc A comprehensive gene expression atlas of sex- and tissue-specificity in the malaria vector, Anopheles gambiae
    Dean A Baker
    Department of Genetics, University of Cambridge, Downing Street, Cambridge CB1 3QA, UK
    BMC Genomics 12:296. 2011
  5. ncbi Reprogramming homing endonuclease specificity through computational design and directed evolution
    Summer B Thyme
    Department of Biochemistry, University of Washington, UW Box 357350, 1705 NE Pacific St, Seattle, WA 98195, USA, Graduate Program in Biomolecular Structure and Design, University of Washington, UW Box 357350, 1705 NE Pacific St, Seattle, WA 98195, USA, Graduate Program in Molecular and Cellular Biology, University of Washington, UW Box 357275, 1959 NE Pacific St, Seattle, WA 98195, USA, Department of Life Sciences, Sir Alexander Fleming Building, Imperial College London, Imperial College Road, London SW7 2AZ, UK, Department of Genetics, University of Cambridge, Downing Street, Cambridge CB1 3QA, UK, Institute for Systems Biology, 401 Terry Avenue N, Seattle, WA 98109, USA and Howard Hughes Medical Institute, University of Washington, UW Box 357350, 1705 NE Pacific St, Seattle, WA 98195, USA
    Nucleic Acids Res 42:2564-76. 2014
  6. ncbi Drosophila melanogaster--the model organism of choice for the complex biology of multi-cellular organisms
    Kathleen M Beckingham
    Department of Biochemistry and Cell Biology, Rice University, Houston, Texas 77251, USA
    Gravit Space Biol Bull 18:17-29. 2005
  7. ncbi Genetics of graviperception in animals
    Kathleen M Beckingham
    Department of Biochemistry and Cell Biology, Rice University, Houston, TX 77005, USA
    Adv Genet 55:105-45. 2005

Detail Information

Publications7

  1. pmc Role of testis-specific gene expression in sex-chromosome evolution of Anopheles gambiae
    Dean A Baker
    Department of Genetics, University of Cambridge, Cambridge CB1 3QA, United Kingdom
    Genetics 189:1117-20. 2011
    ..We suggest that the degeneration of sex chromosomes in this monandrous species is likely the result of pressures from X inactivation, dosage compensation, and sexual antagonism...
  2. pmc Variable sexually dimorphic gene expression in laboratory strains of Drosophila melanogaster
    Dean A Baker
    Department of Genetics, University of Cambridge, Downing Street, Cambridge CB1 3QA, UK
    BMC Genomics 8:454. 2007
    ..Here, our goal was to identify genes that display transcriptional variation between laboratory strains of Drosophila melanogaster, and to explore evidence of gender-biased interactions underlying that variability...
  3. pmc Gene expression during Drosophila melanogaster egg development before and after reproductive diapause
    Dean A Baker
    Department of Genetics, University of Cambridge, Downing Street, Cambridge CB13QA, UK
    BMC Genomics 10:242. 2009
    ..Releasing females from diapause allows collection of relatively synchronous developing egg populations and an investigation of some of the transcriptional dynamics apparent before and after reproductive diapause...
  4. pmc A comprehensive gene expression atlas of sex- and tissue-specificity in the malaria vector, Anopheles gambiae
    Dean A Baker
    Department of Genetics, University of Cambridge, Downing Street, Cambridge CB1 3QA, UK
    BMC Genomics 12:296. 2011
    ..Identifying genes expressed in particular tissues or involved in specific biological processes is an essential part of this process...
  5. ncbi Reprogramming homing endonuclease specificity through computational design and directed evolution
    Summer B Thyme
    Department of Biochemistry, University of Washington, UW Box 357350, 1705 NE Pacific St, Seattle, WA 98195, USA, Graduate Program in Biomolecular Structure and Design, University of Washington, UW Box 357350, 1705 NE Pacific St, Seattle, WA 98195, USA, Graduate Program in Molecular and Cellular Biology, University of Washington, UW Box 357275, 1959 NE Pacific St, Seattle, WA 98195, USA, Department of Life Sciences, Sir Alexander Fleming Building, Imperial College London, Imperial College Road, London SW7 2AZ, UK, Department of Genetics, University of Cambridge, Downing Street, Cambridge CB1 3QA, UK, Institute for Systems Biology, 401 Terry Avenue N, Seattle, WA 98109, USA and Howard Hughes Medical Institute, University of Washington, UW Box 357350, 1705 NE Pacific St, Seattle, WA 98195, USA
    Nucleic Acids Res 42:2564-76. 2014
    ..In the course of this work we observed unanticipated context-dependence between bases which will need to be mechanistically understood for reprogramming of specificity to succeed more generally. ..
  6. ncbi Drosophila melanogaster--the model organism of choice for the complex biology of multi-cellular organisms
    Kathleen M Beckingham
    Department of Biochemistry and Cell Biology, Rice University, Houston, Texas 77251, USA
    Gravit Space Biol Bull 18:17-29. 2005
    ..The growing contribution of Drosophila to our knowledge of gravity-related responses is addressed...
  7. ncbi Genetics of graviperception in animals
    Kathleen M Beckingham
    Department of Biochemistry and Cell Biology, Rice University, Houston, TX 77005, USA
    Adv Genet 55:105-45. 2005
    ..We also discuss the role of large genetic screens in identifying specific genes with roles in mechanosensation and graviperception...