Jayne E Bailey

Summary

Affiliation: University of Bristol
Country: UK

Publications

  1. pmc Psychological advocacy toward healing (PATH): study protocol for a randomized controlled trial
    Gwen Brierley
    Centre for Academic Primary Care, School of Social and Community Medicine, University of Bristol, Bristol, UK
    Trials 14:221. 2013
  2. doi request reprint Validating the inhalation of 7.5% CO(2) in healthy volunteers as a human experimental medicine: a model of generalized anxiety disorder (GAD)
    Jayne E Bailey
    Severnside Alliance for Translational Research, University of Bristol, Bristol, UK
    J Psychopharmacol 25:1192-8. 2011
  3. doi request reprint Preliminary evidence of anxiolytic effects of the CRF(1) receptor antagonist R317573 in the 7.5% CO(2) proof-of-concept experimental model of human anxiety
    Jayne E Bailey
    Severnside Alliance for Translational Research, University of Bristol, Bristol, UK
    J Psychopharmacol 25:1199-206. 2011
  4. doi request reprint A comparison of the effects of a subtype selective and non-selective benzodiazepine receptor agonist in two CO(2) models of experimental human anxiety
    J E Bailey
    Psychopharmacology Unit, University of Bristol, Bristol, UK
    J Psychopharmacol 23:117-22. 2009
  5. doi request reprint GABA-A receptors and the response to CO(2) inhalation - a translational trans-species model of anxiety?
    Jayne E Bailey
    Psychopharmacology Unit, University of Bristol, Dorothy Hodgkin Building, Whitson Street, Bristol BS1 3NY, UK
    Pharmacol Biochem Behav 90:51-7. 2008
  6. ncbi request reprint D-Cycloserine and performance under different states of anxiety in healthy volunteers
    J E Bailey
    Psychopharmacology Unit, University of Bristol, UK
    Psychopharmacology (Berl) 193:579-85. 2007
  7. ncbi request reprint A validation of the 7.5% CO2 model of GAD using paroxetine and lorazepam in healthy volunteers
    Jayne E Bailey
    Psychopharmacology Unit, Department of Respiratory Medicine, University of Bristol, United Bristol Healthcare Trust, UK
    J Psychopharmacol 21:42-9. 2007
  8. doi request reprint The effect of a clinically effective and non-effective dose of lorazepam on 7.5% CO₂-induced anxiety
    Alison Diaper
    Psychopharmacology Unit, University of Bristol, Academic Unit of Psychiatry, Bristol, UK
    Hum Psychopharmacol 27:540-8. 2012
  9. doi request reprint Evaluation of the effects of venlafaxine and pregabalin on the carbon dioxide inhalation models of Generalised Anxiety Disorder and panic
    Alison Diaper
    Psychopharmacology Unit, University of Bristol, Bristol, UK
    J Psychopharmacol 27:135-45. 2013
  10. ncbi request reprint Behavioral and cardiovascular effects of 7.5% CO2 in human volunteers
    Jayne E Bailey
    Psychopharmacology Unit, University of Bristol, The Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, Dorothy Hodgkin Building, Bristol, United Kingdom
    Depress Anxiety 21:18-25. 2005

Collaborators

Detail Information

Publications19

  1. pmc Psychological advocacy toward healing (PATH): study protocol for a randomized controlled trial
    Gwen Brierley
    Centre for Academic Primary Care, School of Social and Community Medicine, University of Bristol, Bristol, UK
    Trials 14:221. 2013
    ....
  2. doi request reprint Validating the inhalation of 7.5% CO(2) in healthy volunteers as a human experimental medicine: a model of generalized anxiety disorder (GAD)
    Jayne E Bailey
    Severnside Alliance for Translational Research, University of Bristol, Bristol, UK
    J Psychopharmacol 25:1192-8. 2011
    ..This review considers these concepts and outlines evidence from a validated healthy volunteer model of generalized anxiety disorder (GAD) following the inhalation of 7.5% CO(2)...
  3. doi request reprint Preliminary evidence of anxiolytic effects of the CRF(1) receptor antagonist R317573 in the 7.5% CO(2) proof-of-concept experimental model of human anxiety
    Jayne E Bailey
    Severnside Alliance for Translational Research, University of Bristol, Bristol, UK
    J Psychopharmacol 25:1199-206. 2011
    ..2 [1.5], PLAC 8.2 [2.2], LZP 1.1 [1.5]). We have shown that a drug that acts to inhibit the CRF(1) receptor shows efficacy in the 7.5% CO(2) model of anxiety in healthy participants...
  4. doi request reprint A comparison of the effects of a subtype selective and non-selective benzodiazepine receptor agonist in two CO(2) models of experimental human anxiety
    J E Bailey
    Psychopharmacology Unit, University of Bristol, Bristol, UK
    J Psychopharmacol 23:117-22. 2009
    ....
  5. doi request reprint GABA-A receptors and the response to CO(2) inhalation - a translational trans-species model of anxiety?
    Jayne E Bailey
    Psychopharmacology Unit, University of Bristol, Dorothy Hodgkin Building, Whitson Street, Bristol BS1 3NY, UK
    Pharmacol Biochem Behav 90:51-7. 2008
    ..This paper reviews some of the evidence and attempts to relate and compare these findings across species from the human to the Drosophila...
  6. ncbi request reprint D-Cycloserine and performance under different states of anxiety in healthy volunteers
    J E Bailey
    Psychopharmacology Unit, University of Bristol, UK
    Psychopharmacology (Berl) 193:579-85. 2007
    ..This study examines the effects of D-cycloserine 50 mg on a task that involves learning. We manipulated anxiety levels to model the effects of high anxiety...
  7. ncbi request reprint A validation of the 7.5% CO2 model of GAD using paroxetine and lorazepam in healthy volunteers
    Jayne E Bailey
    Psychopharmacology Unit, Department of Respiratory Medicine, University of Bristol, United Bristol Healthcare Trust, UK
    J Psychopharmacol 21:42-9. 2007
    ..In these studies we have shown that this CO2 model of anxiety is sensitive to lorazepam and to a lesser extent paroxetine. This gives support to its utility as an experimental model of general anxiety disorder in healthy volunteers...
  8. doi request reprint The effect of a clinically effective and non-effective dose of lorazepam on 7.5% CO₂-induced anxiety
    Alison Diaper
    Psychopharmacology Unit, University of Bristol, Academic Unit of Psychiatry, Bristol, UK
    Hum Psychopharmacol 27:540-8. 2012
    ..5 mg and placebo, and dose-dependent trends were seen in scores for VAS fearful, anxious, stressed, tense, and worried. Results may be indicative of dose-dependent effects of lorazepam in a CO₂ model of anxiety...
  9. doi request reprint Evaluation of the effects of venlafaxine and pregabalin on the carbon dioxide inhalation models of Generalised Anxiety Disorder and panic
    Alison Diaper
    Psychopharmacology Unit, University of Bristol, Bristol, UK
    J Psychopharmacol 27:135-45. 2013
    ..This may be due to a lack of sensitivity of the CO(2) challenges in healthy volunteers to these drug types...
  10. ncbi request reprint Behavioral and cardiovascular effects of 7.5% CO2 in human volunteers
    Jayne E Bailey
    Psychopharmacology Unit, University of Bristol, The Henry Wellcome Laboratories for Integrative Neuroscience and Endocrinology, Dorothy Hodgkin Building, Bristol, United Kingdom
    Depress Anxiety 21:18-25. 2005
    ....
  11. doi request reprint The effects of 7.5% carbon dioxide inhalation on task performance in healthy volunteers
    Alison Diaper
    Psychopharmacology Unit, University of Bristol, Bristol, UK
    J Psychopharmacol 26:487-96. 2012
    ..Therefore, inhalation of 7.5% CO(2) produces effects on task performance which are consistent with anxiety...
  12. doi request reprint The effects of single dose anxiolytic medication on the CO2 models of anxiety: differentiation of subjective and objective measures
    A Papadopoulos
    Psychopharmacology Unit, University of Bristol, Bristol, UK
    J Psychopharmacol 24:649-56. 2010
    ..The lack of anxiolytic actions of propranolol, despite a significant reduction in heart rate, is a further support for a central action of CO2 to produce anxiety...
  13. ncbi request reprint The use of sleep measures to compare a new 5HT1A agonist with buspirone in humans
    Sue J Wilson
    Psychopharmacology Unit, University of Bristol, Bristol, UK
    J Psychopharmacol 19:609-13. 2005
    ..Wakefulness in sleep was significantly greatest after morning eptapirone. REM sleep effects were greatest after evening eptapirone, suggesting a greater effect on central serotonin receptors than that of buspirone...
  14. ncbi request reprint Inhalation of 35% CO(2) results in activation of the HPA axis in healthy volunteers
    Spilios V Argyropoulos
    Psychopharmacology Unit, School of Medical Sciences, University of Bristol, University Walk, UK
    Psychoneuroendocrinology 27:715-29. 2002
    ....
  15. ncbi request reprint Does the brain noradrenaline network mediate the effects of the CO2 challenge?
    J E Bailey
    Psychopharmacology Unit, Medical School, University of Bristol, Bristol, UK
    J Psychopharmacol 17:252-9. 2003
    ..This article examines the evidence and discusses the results of studies from our laboratory in relation to a neuroanatomical model centring on the LC...
  16. ncbi request reprint The application of good clinical practice to challenge tests
    Jayne E Bailey
    Psychopharmacology Unit, University of Bristol, Bristol, UK
    J Psychopharmacol 18:16; author reply 18-9. 2004
  17. ncbi request reprint Effects of 5 weeks of administration of fluoxetine and dothiepin in normal volunteers on sleep, daytime sedation, psychomotor performance and mood
    S J Wilson
    Psychopharmacology Unit, School of Medical Sciences, University of Bristol, Bristol, UK
    J Psychopharmacol 16:321-31. 2002
    ..Driving performance, visual attention and mood ratings showed no treatment effects. Subjective health reports during each 5 weeks of treatment were similar in number for the two drugs but showed a different profile of side-effects...
  18. ncbi request reprint Using sleep to evaluate comparative serotonergic effects of paroxetine and citalopram
    S J Wilson
    Psychopharmacology Unit, University of Bristol, University Walk, Bristol BS8 1TD, UK
    Eur Neuropsychopharmacol 14:367-72. 2004
    ..If similar doses of PAR and CIT have similar effects on central serotonin then they should have similar effects on sleep measures in volunteers...
  19. ncbi request reprint Sleep and daytime sleepiness the next day following single night-time dose of fluvoxamine, dothiepin and placebo in normal volunteers
    S J Wilson
    Psychopharmacology Unit, School of Medical Sciences, University of Bristol, UK
    J Psychopharmacol 14:378-86. 2000
    ..The home-recorded sleep findings after fluvoxamine in this study were very similar to sleep laboratory studies with other antidepressant drugs, thus providing more validation of the home recording method...