C P Bailey

Summary

Affiliation: University of Bristol
Country: UK

Publications

  1. ncbi request reprint Protein kinase C activation enhances morphine-induced rapid desensitization of mu-opioid receptors in mature rat locus ceruleus neurons
    Christopher P Bailey
    Department of Pharmacology, University of Bristol, University Walk, Bristol, United Kingdom
    Mol Pharmacol 66:1592-8. 2004
  2. ncbi request reprint Mu-opioid receptor desensitization in mature rat neurons: lack of interaction between DAMGO and morphine
    Christopher P Bailey
    Department of Pharmacology, University of Bristol, School of Medical Sciences, Bristol BS8 1TD, United Kingdom
    J Neurosci 23:10515-20. 2003
  3. ncbi request reprint Neurokinin-1 receptors in the rat nucleus tractus solitarius: pre- and postsynaptic modulation of glutamate and GABA release
    C P Bailey
    Department of Physiology, University of Bristol, School of Medical Sciences, University Walk, Bristol BS8 1TD, UK
    Neuroscience 127:467-79. 2004
  4. ncbi request reprint Opioids: cellular mechanisms of tolerance and physical dependence
    Chris P Bailey
    Department of Pharmacology, University of Bristol, School of Medical Sciences, Bristol BS8 1TD, UK
    Curr Opin Pharmacol 5:60-8. 2005
  5. ncbi request reprint C-terminal splice variants of the mu-opioid receptor: existence, distribution and functional characteristics
    Sue Oldfield
    Department of Physiology and Pharmacology, University of Bristol, Bristol, UK
    J Neurochem 104:937-45. 2008
  6. ncbi request reprint How important is protein kinase C in mu-opioid receptor desensitization and morphine tolerance?
    Chris P Bailey
    Department of Pharmacology, University of Bristol, Bristol BS8 1TD, UK
    Trends Pharmacol Sci 27:558-65. 2006
  7. pmc μ-opioid receptors: correlation of agonist efficacy for signalling with ability to activate internalization
    Jamie McPherson
    Department of Physiology and Pharmacology, School of Medical Sciences, University of Bristol, Bristol, BS8 1TD, UK
    Mol Pharmacol 78:756-66. 2010
  8. doi request reprint Methadone: does it really have low efficacy at micro-opioid receptors?
    Ivan Rodriguez-Martin
    Department of Physiology and Pharmacology, University of Bristol, Bristol, UK
    Neuroreport 19:589-93. 2008
  9. ncbi request reprint Agonist-selective mechanisms of mu-opioid receptor desensitization in human embryonic kidney 293 cells
    Elizabeth A Johnson
    Department of Pharmacology, University of Bristol, Bristol, BS8 1TD, UK
    Mol Pharmacol 70:676-85. 2006
  10. ncbi request reprint Pairing elevation of [cyclic GMP] with inhibition of PKA produces long-term depression of glutamate release from isolated rat hippocampal presynaptic terminals
    Christopher P Bailey
    Department of Neuroscience, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Eur J Neurosci 17:903-8. 2003

Collaborators

  • Sue Oldfield
  • Mark Connor
  • L F Donaldson
  • Forrest L Smith
  • PATRIC STANTON
  • Wolfgang Muller
  • Karen Maubach
  • Eamonn Kelly
  • Graeme Henderson
  • Jamie McPherson
  • Ivan Rodriguez-Martin
  • Ellen Braksator
  • Russell E Nicholls
  • Elizabeth A Johnson
  • Cornelius Krasel
  • Myma Baptist
  • Steven J Charlton
  • William L Dewey
  • Elizabeth M Rosethorne
  • Javier Llorente
  • Guadalupe Rivero
  • Suleiman Al-Sabah
  • Neil V Marrion
  • Sam Goodchild
  • Eric R Kandel
  • Xiao lei Zhang
  • Ana Gonzalez-Cuello
  • Stuart J Mundell
  • Kellie J Hall
  • Daniel Couch
  • Bruce R Conklin

Detail Information

Publications13

  1. ncbi request reprint Protein kinase C activation enhances morphine-induced rapid desensitization of mu-opioid receptors in mature rat locus ceruleus neurons
    Christopher P Bailey
    Department of Pharmacology, University of Bristol, University Walk, Bristol, United Kingdom
    Mol Pharmacol 66:1592-8. 2004
    ....
  2. ncbi request reprint Mu-opioid receptor desensitization in mature rat neurons: lack of interaction between DAMGO and morphine
    Christopher P Bailey
    Department of Pharmacology, University of Bristol, School of Medical Sciences, Bristol BS8 1TD, United Kingdom
    J Neurosci 23:10515-20. 2003
    ..The data presented here fail to support the theory that low concentrations of DAMGO can increase morphine-induced MOR desensitization or internalization...
  3. ncbi request reprint Neurokinin-1 receptors in the rat nucleus tractus solitarius: pre- and postsynaptic modulation of glutamate and GABA release
    C P Bailey
    Department of Physiology, University of Bristol, School of Medical Sciences, University Walk, Bristol BS8 1TD, UK
    Neuroscience 127:467-79. 2004
    ..Activation of these receptors can result in increases in release of both GABA and glutamate, suggesting a crucial modulatory role for NK1 receptors in the rat nucleus tractus solitarius...
  4. ncbi request reprint Opioids: cellular mechanisms of tolerance and physical dependence
    Chris P Bailey
    Department of Pharmacology, University of Bristol, School of Medical Sciences, Bristol BS8 1TD, UK
    Curr Opin Pharmacol 5:60-8. 2005
    ....
  5. ncbi request reprint C-terminal splice variants of the mu-opioid receptor: existence, distribution and functional characteristics
    Sue Oldfield
    Department of Physiology and Pharmacology, University of Bristol, Bristol, UK
    J Neurochem 104:937-45. 2008
    ..In addition, whereas the rate of desensitisation of MOR1 and MOR1A is agonist-independent, that for MOR1B is agonist-dependent...
  6. ncbi request reprint How important is protein kinase C in mu-opioid receptor desensitization and morphine tolerance?
    Chris P Bailey
    Department of Pharmacology, University of Bristol, Bristol BS8 1TD, UK
    Trends Pharmacol Sci 27:558-65. 2006
    ..Here, we propose that protein kinase C could have a crucial role in the desensitization of mu-opioid receptors by morphine and that this cellular process could contribute to the development and maintenance of morphine tolerance in vivo...
  7. pmc μ-opioid receptors: correlation of agonist efficacy for signalling with ability to activate internalization
    Jamie McPherson
    Department of Physiology and Pharmacology, School of Medical Sciences, University of Bristol, Bristol, BS8 1TD, UK
    Mol Pharmacol 78:756-66. 2010
    ..For the prototypic MOPr agonist morphine, its relatively weak ability to induce MOPr internalization can be explained by its low agonist efficacy...
  8. doi request reprint Methadone: does it really have low efficacy at micro-opioid receptors?
    Ivan Rodriguez-Martin
    Department of Physiology and Pharmacology, University of Bristol, Bristol, UK
    Neuroreport 19:589-93. 2008
    ..It also inhibits small conductance Ca2+-activated K+ (SK2) channels. We conclude that methadone is a full agonist at MOPrs that, as we and others have shown, induces MOPr desensitization and internalization...
  9. ncbi request reprint Agonist-selective mechanisms of mu-opioid receptor desensitization in human embryonic kidney 293 cells
    Elizabeth A Johnson
    Department of Pharmacology, University of Bristol, Bristol, BS8 1TD, UK
    Mol Pharmacol 70:676-85. 2006
    ..These data suggest that opioid agonists induce different conformations of the MOR that are susceptible to different desensitizing and internalization processes...
  10. ncbi request reprint Pairing elevation of [cyclic GMP] with inhibition of PKA produces long-term depression of glutamate release from isolated rat hippocampal presynaptic terminals
    Christopher P Bailey
    Department of Neuroscience, Albert Einstein College of Medicine, 1300 Morris Park Avenue, Bronx, NY 10461, USA
    Eur J Neurosci 17:903-8. 2003
    ..These data demonstrate the existence of a presynaptic, cyclic GMP-PKG dependent cascade capable of expressing LTD of glutamate release from isolated hippocampal nerve terminals...
  11. ncbi request reprint Long-term depression of presynaptic release from the readily releasable vesicle pool induced by NMDA receptor-dependent retrograde nitric oxide
    Patric K Stanton
    Department of Neuroscience, Albert Einstein College of Medicine, Bronx, New York 10461 1602, USA
    J Neurosci 23:5936-44. 2003
    ..Presynaptic LTD of RRP release required activation of NMDA receptors, production and extracellular diffusion of the intercellular messenger NO, and activation of cGMP-dependent protein kinase...
  12. pmc Galpha(i2) inhibition of adenylate cyclase regulates presynaptic activity and unmasks cGMP-dependent long-term depression at Schaffer collateral-CA1 hippocampal synapses
    Christopher P Bailey
    Department of Pharmacy and Pharmacology, University of Bath, Claverton Down, Bath BA2 7AY, United Kingdom
    Learn Mem 15:261-70. 2008
    ....
  13. pmc mGluR2 acts through inhibitory Galpha subunits to regulate transmission and long-term plasticity at hippocampal mossy fiber-CA3 synapses
    Russell E Nicholls
    Center for Neurobiology and Behavior, Howard Hughes Medical Institute, Columbia University, New York, NY 10032, USA
    Proc Natl Acad Sci U S A 103:6380-5. 2006
    ..In addition, the LTP deficit observed in constitutively active Galphai2-expressing mice suggests that mGluR2 activation may serve as a metaplastic switch to permit the induction of LTD by inhibiting LTP...