Genomes and Genes
Elizabeth M Azzato
Affiliation: University of Cambridge
- Effects of common germline genetic variation in cell cycle control genes on breast cancer survival: results from a population-based cohortElizabeth M Azzato
Department of Oncology, University of Cambridge, Strangeways Research Laboratory, Worts Causeway, Cambridge, UK
Breast Cancer Res 10:R47. 2008..Of particular interest are genes involved in cell cycle pathways, which regulate cell division...
- Common single-nucleotide polymorphisms in DNA double-strand break repair genes and breast cancer riskKaren A Pooley
Cancer Research UK Genetic Epidemiology Unit, Strangeways Research Laboratory, Worts Causeway, Cambridge CB1 8RN, United Kingdom
Cancer Epidemiol Biomarkers Prev 17:3482-9. 2008..20; 95% CI, 1.07-1.36; P trend = 0.002). In summary, there was little evidence of breast cancer susceptibility with any of the SNPs studied, but larger studies would be needed to confirm subgroup effects...
- SLC6A3 and body mass index in the Prostate, Lung, Colorectal and Ovarian Cancer Screening TrialElizabeth M Azzato
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, Maryland, USA
BMC Med Genet 10:9. 2009....
- A genome-wide association study of prognosis in breast cancerElizabeth M Azzato
Department of Oncology, Strangeways Research Laboratory, University of Cambridge, Cambridge, United Kingdom
Cancer Epidemiol Biomarkers Prev 19:1140-3. 2010..Traditional clinicopathologic features of breast cancer do not account for all the variation in survival. Germline genetic variation may provide additional prognostic information...
- Common germline polymorphisms in COMT, CYP19A1, ESR1, PGR, SULT1E1 and STS and survival after a diagnosis of breast cancerMiriam S Udler
Strangeways Research Laboratory, Departments of Public Health and Primary Care and Oncology, University of Cambridge, Worts Causeway, Cambridge CB1 8RN, United Kingdom
Int J Cancer 125:2687-96. 2009..These results suggest that COMT rs4818, or a variant it tags, is associated with breast cancer prognosis. Further study of COMT and its putative association with breast cancer prognosis is warranted...
- Maternal EPHX1 polymorphisms and risk of phenytoin-induced congenital malformationsElizabeth M Azzato
Division of Cancer Epidemiology and Genetics, National Cancer Institute, NIH, DHHS, Rockville, Maryland 20852, USA
Pharmacogenet Genomics 20:58-63. 2010....
- Common germline variation in mismatch repair genes and survival after a diagnosis of colorectal cancerThibaud Koessler
Department of Oncology, University of Cambridge, Cambridge, United Kingdom
Int J Cancer 124:1887-91. 2009..59, 95% confidence interval (CI) 0.42-0.82, p-value: 0.001). In conclusion, we find some evidence that common variants in mismatch repair genes may contribute to survival of patients with colorectal cancer...
- PREDICT: a new UK prognostic model that predicts survival following surgery for invasive breast cancerGordon C Wishart
Cambridge Breast Unit, Addenbrooke s Hospital, Hills Road, Cambridge, CB2 2QQ, UK
Breast Cancer Res 12:R1. 2010..The aim of this study was to develop and validate a prognostication model to predict overall and breast cancer specific survival for women treated for early breast cancer in the UK...