Q Aziz

Summary

Affiliation: University of Manchester
Country: UK

Publications

  1. ncbi request reprint Cortical processing of human somatic and visceral sensation
    Q Aziz
    Department of Clinical Neurosciences, Institute of Psychiatry, London SE5 8AF, United Kingdom
    J Neurosci 20:2657-63. 2000
  2. ncbi request reprint Functional neuroimaging of visceral sensation
    Q Aziz
    Department of Gastrointestinal Science, University of Manchester, UK
    J Clin Neurophysiol 17:604-12. 2000
  3. ncbi request reprint Acid sensors in the gut: a taste of things to come
    Q Aziz
    Department of Gastrointestinal Science, University of Manchester, UK
    Eur J Gastroenterol Hepatol 13:885-8. 2001
  4. ncbi request reprint Central neural mechanisms mediating human visceral hypersensitivity
    S Sarkar
    Section of Gastrointestinal Sciences, University of Manchester, Hope Hospital, Salford M6 8HD, United Kingdom
    Am J Physiol Gastrointest Liver Physiol 281:G1196-202. 2001
  5. doi request reprint Personality differences affect brainstem autonomic responses to visceral pain
    P Paine
    Department of Gastrointestinal Sciences, Hope Hospital, University of Manchester, UK
    Neurogastroenterol Motil 21:1155-e98. 2009
  6. ncbi request reprint Neurophysiological evaluation of healthy human anorectal sensation
    M L Harris
    Department of Gastrointestinal Science, University of Manchester, UK
    Am J Physiol Gastrointest Liver Physiol 291:G950-8. 2006
  7. ncbi request reprint Organization and reorganization of human swallowing motor cortex: implications for recovery after stroke
    S Hamdy
    Department of GI Science, Hope Hospital, University of Manchester, Manchester M6 8HD, UK
    Clin Sci (Lond) 99:151-7. 2000
  8. ncbi request reprint Assessing the temporal reproducibility of human esophageal motor-evoked potentials to transcranial magnetic stimulation
    P A Paine
    Department of Gastrointestinal Sciences and Statistics, Hope Hospital, Salford, University of Manchester, United Kingdom
    J Clin Neurophysiol 23:374-80. 2006
  9. ncbi request reprint Explaining oropharyngeal dysphagia after unilateral hemispheric stroke
    S Hamdy
    Department of Gastroenterology, Hope Hospital, University of Manchester, Salford, UK
    Lancet 350:686-92. 1997
  10. pmc Perceptual wind-up in the human oesophagus is enhanced by central sensitisation
    S Sarkar
    Department of GI Science, Clinical Sciences Building, Hope Hospital, Salford, University of Manchester, M6 8HD, UK
    Gut 55:920-5. 2006

Collaborators

Detail Information

Publications23

  1. ncbi request reprint Cortical processing of human somatic and visceral sensation
    Q Aziz
    Department of Clinical Neurosciences, Institute of Psychiatry, London SE5 8AF, United Kingdom
    J Neurosci 20:2657-63. 2000
    ..These findings suggest that cortical specialization in the sensory-discriminative, affective, and cognitive areas of the cortex accounts for the perceptual differences observed between the two sensory modalities...
  2. ncbi request reprint Functional neuroimaging of visceral sensation
    Q Aziz
    Department of Gastrointestinal Science, University of Manchester, UK
    J Clin Neurophysiol 17:604-12. 2000
    ....
  3. ncbi request reprint Acid sensors in the gut: a taste of things to come
    Q Aziz
    Department of Gastrointestinal Science, University of Manchester, UK
    Eur J Gastroenterol Hepatol 13:885-8. 2001
    ..This new insight is likely to lead to a more targeted approach towards treating both visceral and somatic pain...
  4. ncbi request reprint Central neural mechanisms mediating human visceral hypersensitivity
    S Sarkar
    Section of Gastrointestinal Sciences, University of Manchester, Hope Hospital, Salford M6 8HD, United Kingdom
    Am J Physiol Gastrointest Liver Physiol 281:G1196-202. 2001
    ..These findings provide the first electrophysiological evidence that central sensitization contributes to human visceral hypersensitivity...
  5. doi request reprint Personality differences affect brainstem autonomic responses to visceral pain
    P Paine
    Department of Gastrointestinal Sciences, Hope Hospital, University of Manchester, UK
    Neurogastroenterol Motil 21:1155-e98. 2009
    ..These may reflect different psychobiological bases for active and passive defence repertoires. Prevalence and clinical relevance of these endophenotypes as vulnerability factors for pain and emotion disorders warrant further exploration...
  6. ncbi request reprint Neurophysiological evaluation of healthy human anorectal sensation
    M L Harris
    Department of Gastrointestinal Science, University of Manchester, UK
    Am J Physiol Gastrointest Liver Physiol 291:G950-8. 2006
    ..This is of relevance in interpreting findings of neuroimaging studies of anorectal sensation and may provide insight into the physiological characteristics of visceral afferent pathways in health and disease...
  7. ncbi request reprint Organization and reorganization of human swallowing motor cortex: implications for recovery after stroke
    S Hamdy
    Department of GI Science, Hope Hospital, University of Manchester, Manchester M6 8HD, UK
    Clin Sci (Lond) 99:151-7. 2000
    ..In addition, we examine approaches which may be useful in speeding up the process of recovery. Swallowing may turn out to be a useful model for studying central nervous system plasticity...
  8. ncbi request reprint Assessing the temporal reproducibility of human esophageal motor-evoked potentials to transcranial magnetic stimulation
    P A Paine
    Department of Gastrointestinal Sciences and Statistics, Hope Hospital, Salford, University of Manchester, United Kingdom
    J Clin Neurophysiol 23:374-80. 2006
    ....
  9. ncbi request reprint Explaining oropharyngeal dysphagia after unilateral hemispheric stroke
    S Hamdy
    Department of Gastroenterology, Hope Hospital, University of Manchester, Salford, UK
    Lancet 350:686-92. 1997
    ....
  10. pmc Perceptual wind-up in the human oesophagus is enhanced by central sensitisation
    S Sarkar
    Department of GI Science, Clinical Sciences Building, Hope Hospital, Salford, University of Manchester, M6 8HD, UK
    Gut 55:920-5. 2006
    ..3 Hz) is used as a proxy for central sensitisation to investigate pain syndromes where pain hypersensitivity is important (for example, fibromyalgia)...
  11. ncbi request reprint Exploring the neurophysiological basis of chest wall allodynia induced by experimental oesophageal acidification - evidence of central sensitization
    R P Willert
    GI Sciences Department, University of Manchester, Hope Hospital, Salford, Lancs, UK
    Neurogastroenterol Motil 19:270-8. 2007
    ..These data provide objective neurophysiological evidence that CS contributes to the development of somatic allodynia following visceral sensitisation...
  12. pmc Cognitive modulation of the cerebral processing of human oesophageal sensation using functional magnetic resonance imaging
    L J Gregory
    Section of GI Sciences, University of Manchester, Manchester, UK
    Gut 52:1671-7. 2003
    ..While cortical processing of visceral sensation has been described, the role that cognitive factors play in modulating this processing remains unclear...
  13. pmc Brain imaging and functional gastrointestinal disorders: has it helped our understanding?
    A R Hobson
    University of Manchester, Section of GI Sciences, Hope Hospital, Salford, Lancashire, UK
    Gut 53:1198-206. 2004
  14. pmc Physiology and pathophysiology of the swallowing area of human motor cortex
    S Hamdy
    Department of Gastroentinal Science, Hope Hospital, University of Manchester, UK
    Neural Plast 8:91-7. 2001
    ..In addition, we examine approaches that may be useful in speeding up recovery of swallowing. Swallowing may be a useful model in which to study central nervous reorganization after injury...
  15. pmc Functional abdominal pain
    P J Matthews
    Department of Gastrointestinal Sciences, Hope Hospital, University of Manchester, Manchester M6 8HD, UK
    Postgrad Med J 81:448-55. 2005
    ....
  16. doi request reprint Randomised clinical trial: pregabalin attenuates the development of acid-induced oesophageal hypersensitivity in healthy volunteers - a placebo-controlled study
    Y C Chua
    Wingate Institute, Centre for Digestive Diseases, Barts and the London School of Medicine and Dentistry, Queen Mary University of London, UK
    Aliment Pharmacol Ther 35:319-26. 2012
    ..The effects of pregabalin, a centrally-acting modulator of voltage-sensitive calcium channels, on development of acid-induced oesophageal hypersensitivity remain unknown...
  17. pmc Effect of childhood adversity on health related quality of life in patients with upper abdominal or chest pain
    A M Biggs
    School of Psychiatry and Behavioural Sciences, Unit of Chronic Disease Epidemiology, Rawnsley Building, University of Manchester Medical School, Manchester Royal Infirmary, Oxford Road, Manchester M13 9PT, UK
    Gut 53:180-6. 2004
    ....
  18. ncbi request reprint Brain-gut interaction in irritable bowel syndrome
    M L Harris
    Department of Gastrointestinal Science, University of Manchester, Salford M6 8HD
    Hosp Med 64:264-9. 2003
    ..The mechanism of pain is likely to be either peripheral or central sensitization of gut nerves or aberrant brain processing. Functional brain techniques are now allowing the study of brain-gut interactions...
  19. ncbi request reprint Cortical processing of visceral and somatic stimulation: differentiating pain intensity from unpleasantness
    P Dunckley
    Department of Human Anatomy and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, UK
    Neuroscience 133:533-42. 2005
    ..We believe that the observed patterns of activation represent the differences in cortical process of interoceptive (visceral) and exteroceptive (somatic) stimuli when matched for unpleasantness...
  20. ncbi request reprint Attentional modulation of visceral and somatic pain
    P Dunckley
    Department of Physiology, Anatomy and Genetics, Oxford, UK
    Neurogastroenterol Motil 19:569-77. 2007
    ..These results suggest that pain intensity perception during attentional modulation is reflected in the primary somatosensory cortex (visceral pain) and aIns cortex activity (somatic pain)...
  21. ncbi request reprint Visceral hypersensitivity in non-erosive reflux disease
    C H Knowles
    Neurogastroenterology Group, Centres for Academic Surgery, Institute of Cellular and Molecular Science, Barts and The London, Queen Mary s School of Medicine and Dentistry, Whitechapel, London, UK
    Gut 57:674-83. 2008
  22. ncbi request reprint Oesophageal afferent pathway sensitivity in non-erosive reflux disease
    A R Hobson
    Immuno Inflammation CEDD, GlaxoSmithKline Medicines Research Centre, Stevenage, Hertfordshire, UK
    Neurogastroenterol Motil 20:877-83. 2008
    ..Increased oesophageal afferent pain sensitivity may play an important role in a subset of NERD and could offer an alternate therapeutic target...
  23. ncbi request reprint Dissociating the spatio-temporal characteristics of cortical neuronal activity associated with human volitional swallowing in the healthy adult brain
    P L Furlong
    The Wellcome Trust Laboratory for MEG Studies, Neurosciences Research Institute, Aston University, Birmingham, UK
    Neuroimage 22:1447-55. 2004
    ..Thus, the ability to non-invasively image this network, with intra-individual and high temporal resolution, provides new insights into the brain processing of human swallowing...