Research Topics
| Paul AuroraSummaryAffiliation: University College London Country: UK Publications
| Collaborators
|
Detail Information
Publications
Quality control for spirometry in preschool children with and without lung diseasePaul Aurora
Portex Respiratory Unit, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
Am J Respir Crit Care Med 169:1152-9. 2004..We describe recommendations for modified start of test and repeatability criteria for this age group, and for improvements in software to facilitate better quality control...
Lung clearance index at 4 years predicts subsequent lung function in children with cystic fibrosisPaul Aurora
Portex Respiratory Unit, UCL Institute of Child Health, 30 Guilford St, London WC1N 1EH, UK
Am J Respir Crit Care Med 183:752-8. 2011..There is an urgent need for alternative surrogates that detect early lung disease and track through early childhood...- Gas mixing efficiency from birth to adulthood measured by multiple-breath washoutPaul Aurora
Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London, UK
Respir Physiol Neurobiol 148:125-39. 2005..Although methodological and analytical issues remain, the future clinical and research applications of MBW justify accelerated research in this field... 
Multiple breath inert gas washout as a measure of ventilation distribution in children with cystic fibrosisP Aurora
Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London, UK
Thorax 59:1068-73. 2004....- Multiple-breath washout as a marker of lung disease in preschool children with cystic fibrosisPaul Aurora
Portex Respiratory Unit, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
Am J Respir Crit Care Med 171:249-56. 2005..Most preschool children can perform multiple-breath washout, plethysmography, and spirometry at first attempt. Multiple-breath washout detects abnormal lung function in children with CF more readily than plethysmography or spirometry... - Lung transplantation for cystic fibrosisPaul Aurora
Cardiothoracic Transplant Unit, Great Ormond Street Hospital for Children, UK
J R Soc Med 100:46-52. 2007 - Registry of the International Society for Heart and Lung Transplantation: tenth official pediatric lung and heart/lung transplantation report--2007Paul Aurora
International Society for Heart and Lung Transplantation, Addison, Texas, USA
J Heart Lung Transplant 26:1223-8. 2007..All figures and tables included in this report and additional supplementary slides are available from the ISHLT website (www.ishlt.org/registries)... - Multiple-breath washout in preschool children--FRC and ventilation inhomogeneityPaul Aurora
Portex Respiratory Unit, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
Paediatr Respir Rev 7:S14-6. 2006..Guidelines for data collection and interpretation in this age group will shortly be published by the European Respiratory Society and the American Thoracic Society... - Registry of the International Society for Heart and Lung Transplantation: tenth official pediatric heart transplantation report--2007Mark M Boucek
International Society for Heart and Lung Transplantation, Addison, Texas, USA
J Heart Lung Transplant 26:796-807. 2007 - Registry of the International Society for Heart and Lung Transplantation: twenty-fourth official adult heart transplant report--2007David O Taylor
International Society for Heart and Lung Transplantation, Addison, Texas, USA
J Heart Lung Transplant 26:769-81. 2007 - Lung function from infancy to the preschool years after clinical diagnosis of cystic fibrosisWanda J Kozlowska
Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, UCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
Am J Respir Crit Care Med 178:42-9. 2008..After recent standardization of forced expiratory maneuvers for both infants and preschool children, longitudinal measurements are now possible from birth... - Registry of the International Society for Heart and Lung Transplantation: introduction to the 2007 annual reports--100,000 transplants and going strongMarshall I Hertz
International Society for Heart and Lung Transplantation, Addison, Texas, USA
J Heart Lung Transplant 26:763-8. 2007 - Monitoring of Epstein-Barr viral load in pediatric heart and lung transplant recipients by real-time polymerase chain reactionChristian Benden
Cardio Respiratory and Critical Care Division, Great Ormond Street Hospital for Children, National Health Service Trust, London, UK
J Heart Lung Transplant 24:2103-8. 2005..We report the longitudinal surveillance of EBV for all recipients of heart (HTx), heart-lung (HLTx) and lung (LTx) transplants at our institution... - Chronic kidney disease in children following lung and heart-lung transplantationChristian Benden
Cardio Respiratory and Critical Care Division, Great Ormond Street Hospital for Children NHS Trust, London, UK
Pediatr Transplant 13:104-10. 2009..Unlike in adults, we were unable to detect any predictors of renal impairment in pediatric lung transplant recipients... - Pre-implantation basiliximab reduces incidence of early acute rejection in pediatric heart transplantationNicholas Grundy
Department of Cardiology, Great Ormond Street Hospital for Children, London, UK
J Heart Lung Transplant 28:1279-84. 2009..In this study we aim to determine whether pre-operative administration of basiliximab is beneficial in preventing early heart allograft rejection... - Lung transplantation in children with idiopathic pulmonary arterial hypertensionAstrid E Lammers
Great Ormond Street Hospital for Children, Great Ormond Street, London WC1N 3JH, UK
Pediatr Pulmonol 45:263-9. 2010..Despite improved medical therapy, transplantation (Tx) represents the only option for end-stage pulmonary vascular disease... - Symptom-pattern phenotype and pulmonary function in preschool wheezersSamatha Sonnappa
Portex Unit, Respiratory Medicine and Physiology, UCL Institute of Child Health, London, United Kingdom
J Allergy Clin Immunol 126:519-26.e1-7. 2010..Pulmonary function in preschool wheezing phenotypes based on wheeze onset and duration and atopic status has been extensively described but has not been studied in symptom-pattern phenotypes of episodic (viral) and multiple-trigger wheeze... - Spirometry in the pre-school age groupWanda J Kozlowska
Portex Anaesthesia, Intensive Therapy and Respiratory Unit, Level 6, Cardiac Wing, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
Paediatr Respir Rev 6:267-72. 2005..Accurate results can be obtained provided care and attention are paid to applying quality-control criteria suitable for this age group. The biggest challenge is to make the testing fun... - When should children be referred for lung or heart-lung transplantation?Paul Aurora
Respiratory Unit, Great Ormond Street Hospital for Children, Portex Respiratory Unit, Institute of Child Health, London, UK
Pediatr Pulmonol Suppl 26:116-8. 2004 - High prevalence of gastroesophageal reflux in children after lung transplantationChristian Benden
Cardio Respiratory and Critical Care Division, Great Ormond Street Hospital for Children National Health Service Trust, London, UK
Pediatr Pulmonol 40:68-71. 2005..There was no association between severity of GERD and peak spirometry results posttransplant. Moderate to severe GERD is common following lung transplantation in children... - Exercise tolerance in children with cystic fibrosis undergoing lung transplantation assessmentP Aurora
Cardiorespiratory and Critical Care Directorate, Great Ormond Street Hospital for Children, London, UK
Eur Respir J 18:293-7. 2001..The 3-min step test produced a greater fall in Sa,O2 and a greater rise in HR than the 6-min walk test in children with moderate to severe CF lung disease. It may be of value when assessing a child's suitability for lung transplantation... - Lung transplantation and life extension in children with cystic fibrosisP Aurora
Cardiorespiratory and Critical Care Directorate, Great Ormond Street Hospital for Children NHS Trust, London, UK
Lancet 354:1591-3. 1999..We examined the effect of lung or heart-lung transplantation on the survival of a cohort of children with cystic fibrosis and severe lung disease... - Lung transplantation and end of life issues in cystic fibrosisP Aurora
Department of Paediatric Respiratory Medicine, Royal Brompton and Harefield NHS Trust, London, UK
Paediatr Respir Rev 1:114-20. 2000..This article summarizes the current status of lung transplantation, including current referral guidelines and contraindications and also addresses current practice in terminal care... - Transbronchial biopsies provide longitudinal evidence for epithelial chimerism in children following sex mismatched lung transplantationH Spencer
Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London WC1N 3JH, UK
Thorax 60:60-2. 2005..CONCLUSIONS: This study has demonstrated proof of principle for long term chimerism in lung epithelium. Transbronchial biopsies may provide a new method for studying the kinetics of stem cell engraftment in the lung... - An official American Thoracic Society/European Respiratory Society statement: pulmonary function testing in preschool childrenNicole Beydon
Am J Respir Crit Care Med 175:1304-45. 2007 - Registry of the International Society for Heart and Lung Transplantation: twenty-fourth official adult lung and heart-lung transplantation report-2007Elbert P Trulock
Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St. Louis, Missouri 63110, USA
J Heart Lung Transplant 26:782-95. 2007 - Lung transplantation in children with cystic fibrosis: a view from EuropePaul Aurora
Am J Respir Crit Care Med 177:935-6. 2008 - Lung transplantation and survival in children with cystic fibrosis: solid statistics--flawed interpretationStuart C Sweet
Department of Pediatrics, Washington University, St Louis, MO 63110, USA
Pediatr Transplant 12:129-36. 2008.... - Increased mortality after pulmonary fungal infection within the first year after pediatric lung transplantationLara A Danziger-Isakov
Department of Pediatric Infectious Diseases, Cleveland Clinic, Cleveland, Ohio 44195, USA
J Heart Lung Transplant 27:655-61. 2008..Risk factors, morbidity and mortality from pulmonary fungal infections (PFIs) within the first year after pediatric lung transplant have not previously been characterized... - Variability in standard care for cytomegalovirus prevention and detection in pediatric lung transplantation: survey of eight pediatric lung transplant programsLara A Danziger-Isakov
Department of Pediatrics, Washington University School of Medicine, St Louis Children s Hospital, St Louis, MO, USA
Pediatr Transplant 7:469-73. 2003..A retrospective analysis among these centers is being conducted to evaluate the efficacy of these approaches... - Positive pretransplantation cytomegalovirus serology is a risk factor for cardiac allograft vasculopathy in childrenTarique Hussain
Paediatric Cardiology, Great Ormond Street Hospital, London, United Kingdom
Circulation 115:1798-805. 2007..The purpose of this retrospective observational study was to evaluate the effect of CMV on outcome after heart transplantation in children... - Variability in immunization guidelines in children before and after lung transplantationChristian Benden
Division of Pulmonary Medicine and Lung Transplantation, University Hospital, Zurich, Switzerland
Pediatr Transplant 11:882-7. 2007..Current vaccination practices of pediatric lung transplant centers are heterogeneous. The lung transplant community would be well served by studies designed to evaluate the efficacy of vaccinations in this population...