Paul Aurora

Summary

Affiliation: University College London
Country: UK

Publications

  1. ncbi request reprint Quality control for spirometry in preschool children with and without lung disease
    Paul Aurora
    Portex Respiratory Unit, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Am J Respir Crit Care Med 169:1152-9. 2004
  2. ncbi request reprint Multiple-breath washout in preschool children--FRC and ventilation inhomogeneity
    Paul Aurora
    Portex Respiratory Unit, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Paediatr Respir Rev 7:S14-6. 2006
  3. ncbi request reprint Gas mixing efficiency from birth to adulthood measured by multiple-breath washout
    Paul Aurora
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London, UK
    Respir Physiol Neurobiol 148:125-39. 2005
  4. ncbi request reprint Lung transplantation for cystic fibrosis
    Paul Aurora
    Cardiothoracic Transplant Unit, Great Ormond Street Hospital for Children, UK
    J R Soc Med 100:46-52. 2007
  5. pmc Multiple breath inert gas washout as a measure of ventilation distribution in children with cystic fibrosis
    P Aurora
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London, UK
    Thorax 59:1068-73. 2004
  6. ncbi request reprint Multiple-breath washout as a marker of lung disease in preschool children with cystic fibrosis
    Paul Aurora
    Portex Respiratory Unit, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Am J Respir Crit Care Med 171:249-56. 2005
  7. ncbi request reprint Registry of the International Society for Heart and Lung Transplantation: tenth official pediatric lung and heart/lung transplantation report--2007
    Paul Aurora
    International Society for Heart and Lung Transplantation, Addison, Texas, USA
    J Heart Lung Transplant 26:1223-8. 2007
  8. doi request reprint Lung clearance index at 4 years predicts subsequent lung function in children with cystic fibrosis
    Paul Aurora
    Portex Respiratory Unit, UCL Institute of Child Health, 30 Guilford St, London WC1N 1EH, UK
    Am J Respir Crit Care Med 183:752-8. 2011
  9. doi request reprint Age and height dependence of lung clearance index and functional residual capacity
    Sooky Lum
    Portex Respiratory Unit, UCL Institute of Child Health, London, UK
    Eur Respir J 41:1371-7. 2013
  10. ncbi request reprint Registry of the International Society for Heart and Lung Transplantation: tenth official pediatric heart transplantation report--2007
    Mark M Boucek
    International Society for Heart and Lung Transplantation, Addison, Texas, USA
    J Heart Lung Transplant 26:796-807. 2007

Detail Information

Publications35

  1. ncbi request reprint Quality control for spirometry in preschool children with and without lung disease
    Paul Aurora
    Portex Respiratory Unit, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Am J Respir Crit Care Med 169:1152-9. 2004
    ..We describe recommendations for modified start of test and repeatability criteria for this age group, and for improvements in software to facilitate better quality control...
  2. ncbi request reprint Multiple-breath washout in preschool children--FRC and ventilation inhomogeneity
    Paul Aurora
    Portex Respiratory Unit, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Paediatr Respir Rev 7:S14-6. 2006
    ..Guidelines for data collection and interpretation in this age group will shortly be published by the European Respiratory Society and the American Thoracic Society...
  3. ncbi request reprint Gas mixing efficiency from birth to adulthood measured by multiple-breath washout
    Paul Aurora
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London, UK
    Respir Physiol Neurobiol 148:125-39. 2005
    ..Although methodological and analytical issues remain, the future clinical and research applications of MBW justify accelerated research in this field...
  4. ncbi request reprint Lung transplantation for cystic fibrosis
    Paul Aurora
    Cardiothoracic Transplant Unit, Great Ormond Street Hospital for Children, UK
    J R Soc Med 100:46-52. 2007
  5. pmc Multiple breath inert gas washout as a measure of ventilation distribution in children with cystic fibrosis
    P Aurora
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health, London, UK
    Thorax 59:1068-73. 2004
    ....
  6. ncbi request reprint Multiple-breath washout as a marker of lung disease in preschool children with cystic fibrosis
    Paul Aurora
    Portex Respiratory Unit, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Am J Respir Crit Care Med 171:249-56. 2005
    ..Most preschool children can perform multiple-breath washout, plethysmography, and spirometry at first attempt. Multiple-breath washout detects abnormal lung function in children with CF more readily than plethysmography or spirometry...
  7. ncbi request reprint Registry of the International Society for Heart and Lung Transplantation: tenth official pediatric lung and heart/lung transplantation report--2007
    Paul Aurora
    International Society for Heart and Lung Transplantation, Addison, Texas, USA
    J Heart Lung Transplant 26:1223-8. 2007
    ..All figures and tables included in this report and additional supplementary slides are available from the ISHLT website (www.ishlt.org/registries)...
  8. doi request reprint Lung clearance index at 4 years predicts subsequent lung function in children with cystic fibrosis
    Paul Aurora
    Portex Respiratory Unit, UCL Institute of Child Health, 30 Guilford St, London WC1N 1EH, UK
    Am J Respir Crit Care Med 183:752-8. 2011
    ..There is an urgent need for alternative surrogates that detect early lung disease and track through early childhood...
  9. doi request reprint Age and height dependence of lung clearance index and functional residual capacity
    Sooky Lum
    Portex Respiratory Unit, UCL Institute of Child Health, London, UK
    Eur Respir J 41:1371-7. 2013
    ..Although a constant upper normal limit would suffice for cross-sectional clinical assessments from 6 years of age, appropriate reference equations are essential for accurate interpretation of results during early childhood...
  10. ncbi request reprint Registry of the International Society for Heart and Lung Transplantation: tenth official pediatric heart transplantation report--2007
    Mark M Boucek
    International Society for Heart and Lung Transplantation, Addison, Texas, USA
    J Heart Lung Transplant 26:796-807. 2007
  11. ncbi request reprint Registry of the International Society for Heart and Lung Transplantation: twenty-fourth official adult heart transplant report--2007
    David O Taylor
    International Society for Heart and Lung Transplantation, Addison, Texas, USA
    J Heart Lung Transplant 26:769-81. 2007
  12. doi request reprint Lung function from infancy to the preschool years after clinical diagnosis of cystic fibrosis
    Wanda J Kozlowska
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, UCL Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Am J Respir Crit Care Med 178:42-9. 2008
    ..After recent standardization of forced expiratory maneuvers for both infants and preschool children, longitudinal measurements are now possible from birth...
  13. ncbi request reprint Registry of the International Society for Heart and Lung Transplantation: introduction to the 2007 annual reports--100,000 transplants and going strong
    Marshall I Hertz
    International Society for Heart and Lung Transplantation, Addison, Texas, USA
    J Heart Lung Transplant 26:763-8. 2007
  14. doi request reprint Repeatability and bronchodilator reversibility of lung function in young children
    Samatha Sonnappa
    Portex Unit, Respiratory Medicine and Physiology, UCL Institute of Child Health, London, UK
    Eur Respir J 42:116-24. 2013
    ..These findings will help to interpret the effect of therapeutic interventions in children with respiratory diseases. ..
  15. doi request reprint Abbreviated multi-breath washout for calculation of lung clearance index
    Paul D Robinson
    Portex Respiratory Unit, UCL Institute of Child Health, London
    Pediatr Pulmonol 48:336-43. 2013
    ..Adult guidelines recommend three technically acceptable tests with FRC values within 10%, whilst preschool guidelines recommend two such tests. Feasibility of and need for recommendations in children is unclear...
  16. ncbi request reprint Monitoring of Epstein-Barr viral load in pediatric heart and lung transplant recipients by real-time polymerase chain reaction
    Christian Benden
    Cardio Respiratory and Critical Care Division, Great Ormond Street Hospital for Children, National Health Service Trust, London, UK
    J Heart Lung Transplant 24:2103-8. 2005
    ..We report the longitudinal surveillance of EBV for all recipients of heart (HTx), heart-lung (HLTx) and lung (LTx) transplants at our institution...
  17. doi request reprint Pre-implantation basiliximab reduces incidence of early acute rejection in pediatric heart transplantation
    Nicholas Grundy
    Department of Cardiology, Great Ormond Street Hospital for Children, London, UK
    J Heart Lung Transplant 28:1279-84. 2009
    ..In this study we aim to determine whether pre-operative administration of basiliximab is beneficial in preventing early heart allograft rejection...
  18. doi request reprint Chronic kidney disease in children following lung and heart-lung transplantation
    Christian Benden
    Cardio Respiratory and Critical Care Division, Great Ormond Street Hospital for Children NHS Trust, London, UK
    Pediatr Transplant 13:104-10. 2009
    ..Unlike in adults, we were unable to detect any predictors of renal impairment in pediatric lung transplant recipients...
  19. doi request reprint Lung transplantation in children with idiopathic pulmonary arterial hypertension
    Astrid E Lammers
    Great Ormond Street Hospital for Children, Great Ormond Street, London WC1N 3JH, UK
    Pediatr Pulmonol 45:263-9. 2010
    ..Despite improved medical therapy, transplantation (Tx) represents the only option for end-stage pulmonary vascular disease...
  20. doi request reprint Symptom-pattern phenotype and pulmonary function in preschool wheezers
    Samatha Sonnappa
    Portex Unit, Respiratory Medicine and Physiology, UCL Institute of Child Health, London, United Kingdom
    J Allergy Clin Immunol 126:519-26.e1-7. 2010
    ..Pulmonary function in preschool wheezing phenotypes based on wheeze onset and duration and atopic status has been extensively described but has not been studied in symptom-pattern phenotypes of episodic (viral) and multiple-trigger wheeze...
  21. ncbi request reprint When should children be referred for lung or heart-lung transplantation?
    Paul Aurora
    Respiratory Unit, Great Ormond Street Hospital for Children, Portex Respiratory Unit, Institute of Child Health, London, UK
    Pediatr Pulmonol Suppl 26:116-8. 2004
  22. ncbi request reprint Spirometry in the pre-school age group
    Wanda J Kozlowska
    Portex Anaesthesia, Intensive Therapy and Respiratory Unit, Level 6, Cardiac Wing, Institute of Child Health, 30 Guilford Street, London WC1N 1EH, UK
    Paediatr Respir Rev 6:267-72. 2005
    ..Accurate results can be obtained provided care and attention are paid to applying quality-control criteria suitable for this age group. The biggest challenge is to make the testing fun...
  23. ncbi request reprint High prevalence of gastroesophageal reflux in children after lung transplantation
    Christian Benden
    Cardio Respiratory and Critical Care Division, Great Ormond Street Hospital for Children National Health Service Trust, London, UK
    Pediatr Pulmonol 40:68-71. 2005
    ..There was no association between severity of GERD and peak spirometry results posttransplant. Moderate to severe GERD is common following lung transplantation in children...
  24. ncbi request reprint Exercise tolerance in children with cystic fibrosis undergoing lung transplantation assessment
    P Aurora
    Cardiorespiratory and Critical Care Directorate, Great Ormond Street Hospital for Children, London, UK
    Eur Respir J 18:293-7. 2001
    ..The 3-min step test produced a greater fall in Sa,O2 and a greater rise in HR than the 6-min walk test in children with moderate to severe CF lung disease. It may be of value when assessing a child's suitability for lung transplantation...
  25. ncbi request reprint Lung transplantation and life extension in children with cystic fibrosis
    P Aurora
    Cardiorespiratory and Critical Care Directorate, Great Ormond Street Hospital for Children NHS Trust, London, UK
    Lancet 354:1591-3. 1999
    ..We examined the effect of lung or heart-lung transplantation on the survival of a cohort of children with cystic fibrosis and severe lung disease...
  26. pmc Transbronchial biopsies provide longitudinal evidence for epithelial chimerism in children following sex mismatched lung transplantation
    H Spencer
    Portex Anaesthesia, Intensive Therapy and Respiratory Medicine Unit, Institute of Child Health and Great Ormond Street Hospital for Children NHS Trust, Great Ormond Street, London WC1N 3JH, UK
    Thorax 60:60-2. 2005
    ..The aim of this study was to assess whether transbronchial biopsies could be used to study the time course of chimerism following lung transplantation...
  27. ncbi request reprint Lung transplantation and end of life issues in cystic fibrosis
    P Aurora
    Department of Paediatric Respiratory Medicine, Royal Brompton and Harefield NHS Trust, London, UK
    Paediatr Respir Rev 1:114-20. 2000
    ..This article summarizes the current status of lung transplantation, including current referral guidelines and contraindications and also addresses current practice in terminal care...
  28. doi request reprint Lung transplantation in children with cystic fibrosis: a view from Europe
    Paul Aurora
    Am J Respir Crit Care Med 177:935-6. 2008
  29. doi request reprint Lung transplantation and survival in children with cystic fibrosis: solid statistics--flawed interpretation
    Stuart C Sweet
    Department of Pediatrics, Washington University, St Louis, MO 63110, USA
    Pediatr Transplant 12:129-36. 2008
    ....
  30. ncbi request reprint Registry of the International Society for Heart and Lung Transplantation: twenty-fourth official adult lung and heart-lung transplantation report-2007
    Elbert P Trulock
    Division of Pulmonary and Critical Care Medicine, Washington University School of Medicine, St Louis, Missouri 63110, USA
    J Heart Lung Transplant 26:782-95. 2007
  31. ncbi request reprint An official American Thoracic Society/European Respiratory Society statement: pulmonary function testing in preschool children
    Nicole Beydon
    Am J Respir Crit Care Med 175:1304-45. 2007
  32. pmc Increased mortality after pulmonary fungal infection within the first year after pediatric lung transplantation
    Lara A Danziger-Isakov
    Department of Pediatric Infectious Diseases, Cleveland Clinic, Cleveland, Ohio 44195, USA
    J Heart Lung Transplant 27:655-61. 2008
    ..Risk factors, morbidity and mortality from pulmonary fungal infections (PFIs) within the first year after pediatric lung transplant have not previously been characterized...
  33. ncbi request reprint Variability in standard care for cytomegalovirus prevention and detection in pediatric lung transplantation: survey of eight pediatric lung transplant programs
    Lara A Danziger-Isakov
    Department of Pediatrics, Washington University School of Medicine, St Louis Children s Hospital, St Louis, MO, USA
    Pediatr Transplant 7:469-73. 2003
    ..A retrospective analysis among these centers is being conducted to evaluate the efficacy of these approaches...
  34. ncbi request reprint Variability in immunization guidelines in children before and after lung transplantation
    Christian Benden
    Division of Pulmonary Medicine and Lung Transplantation, University Hospital, Zurich, Switzerland
    Pediatr Transplant 11:882-7. 2007
    ..Current vaccination practices of pediatric lung transplant centers are heterogeneous. The lung transplant community would be well served by studies designed to evaluate the efficacy of vaccinations in this population...
  35. ncbi request reprint Positive pretransplantation cytomegalovirus serology is a risk factor for cardiac allograft vasculopathy in children
    Tarique Hussain
    Paediatric Cardiology, Great Ormond Street Hospital, London, United Kingdom
    Circulation 115:1798-805. 2007
    ..The purpose of this retrospective observational study was to evaluate the effect of CMV on outcome after heart transplantation in children...