- Haptoglobin HP2-2 genotype, alpha-thalassaemia and acute seizures in children living in a malaria-endemic areaRichard Idro
Centre for Geographic Medicine Research Coast, Kenya Medical Research Institute, Kilifi, Kenya
Epilepsy Res 81:114-8. 2008..We conclude that the HP2-2 polymorphism and deletions in alpha-globin gene are not risk factors for acute seizures in children. Future studies should examine other susceptibility genes...
- Tumor necrosis factor SNP haplotypes are associated with iron deficiency anemia in West African childrenSarah H Atkinson
Medical Research Council MRC Keneba and MRC Laboratories, Banjul, The Gambia
Blood 112:4276-83. 2008..Thus, TNF appears to be a risk factor for iron deficiency and IDA in children in a malaria-endemic environment and this is likely to be due to a TNF-alpha-induced block in iron absorption...
- Seasonal childhood anaemia in West Africa is associated with the haptoglobin 2-2 genotypeSarah H Atkinson
Medical Research Council Laboratories, Banjul, The Gambia
PLoS Med 3:e172. 2006..Previous studies examined the importance of haptoglobin polymorphism in malaria and iron homeostasis, but it is unknown whether haptoglobin genotype might be a risk factor for anaemia in children in a malaria-endemic area...