E A Ashley

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. ncbi Computer applications in the interpretation of the exercise electrocardiogram
    E A Ashley
    Department of Cardiovascular Medicine, University of Oxford, Oxford Cardiac Center, England
    Sports Med 30:231-48. 2000
  2. ncbi Exercise testing in clinical medicine
    E A Ashley
    Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, UK
    Lancet 356:1592-7. 2000
  3. ncbi Cardiac nitric oxide synthase 1 regulates basal and beta-adrenergic contractility in murine ventricular myocytes
    Euan A Ashley
    University Department of Cardiovascular Medicine, John Radcliffe Hospital, Oxford, UK
    Circulation 105:3011-6. 2002
  4. ncbi Diagnosing coronary artery disease in diabetic patients
    Euan A Ashley
    Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Diabetes Metab Res Rev 18:201-8. 2002
  5. ncbi An evidence-based review of the resting electrocardiogram as a screening technique for heart disease
    E A Ashley
    Department of Cardiovascular Medicine, John Radcliffe Hospital, University of Oxford, UK
    Prog Cardiovasc Dis 44:55-67. 2001
  6. ncbi Cardiac neuronal nitric oxide synthase isoform regulates myocardial contraction and calcium handling
    Claire E Sears
    Department of Cardiovascular Medicine, Oxford University, John Radcliffe Hospital, Oxford, OX3 9DU, UK
    Circ Res 92:e52-9. 2003
  7. pmc Nitric oxide control of cardiac function: is neuronal nitric oxide synthase a key component?
    Claire E Sears
    Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Philos Trans R Soc Lond B Biol Sci 359:1021-44. 2004
  8. ncbi Prognostic value of heart rate increase at onset of exercise testing
    Nicholas J Leeper
    Stanford University Medical Center, Stanford University Medical School, Calif, USA
    Circulation 115:468-74. 2007
  9. doi Ventricular arrhythmias during clinical treadmill testing and prognosis
    Frederick E Dewey
    Stanford University Medical School, Palo Alto, California, USA
    Arch Intern Med 168:225-34. 2008
  10. doi Does size matter? Clinical applications of scaling cardiac size and function for body size
    Frederick E Dewey
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Circulation 117:2279-87. 2008

Collaborators

  • V F Froelicher
  • J Myers
  • Raymond Tabibiazar
  • Joshua M Spin
  • B Casadei
  • Craig A Lygate
  • Grzegorz Piecha
  • Daniel M Bernstein
  • P A Heidenreich
  • Claire E Sears
  • Stefan Neubauer
  • Andrew J Patterson
  • David Rosenthal
  • Derek A Terrar
  • Frederick E Dewey
  • Nicholas J Leeper
  • Philip S Tsao
  • Thomas Quertermous
  • Jennifer Y King
  • Mary M Chen
  • Hyung J Chun
  • Ralph Rabkin
  • David Hadley
  • Ahmad Y Sheikh
  • Patrick Yue
  • Anya Tsalenko
  • Amir Ben-Dor
  • Eugene Yang
  • Laurakay Bruhn
  • Zohar Yakhini
  • Ziad A Ali
  • Marie Luise Gross
  • Yu Chen
  • Daniel J Murphy
  • Michael J Lipinski
  • Ramendra K Kundu
  • Yoko Kojima
  • Joshua P Anderson
  • Sumita Sood
  • Rani Agrawal
  • Lixin Zheng
  • Ibrahim Awwad
  • Ryan S Williams
  • William Clusin
  • Difei Sun
  • John R Kapoor
  • Nathan E Pearl
  • Michael J Lenardo
  • Phillip C Yang
  • Feng Cao
  • Masahiro Terashima
  • Joseph Wu
  • David Charo
  • Swee Yaw Tan
  • Grant Hoyt
  • Marcus Sandri
  • Robert C Robbins
  • Takayasu Arai
  • Rossella Ferrara
  • Annette Adler
  • David Xing Fei Deng
  • Robert Kincaid
  • Allan Kuchinsky
  • Philip Tsao
  • Clifton Watt
  • Peng Zhang
  • Aditya Vailaya
  • Andrew Connolly
  • Brett Fenster
  • David X F Deng
  • Robert Robbins
  • Theresa McDonagh
  • Michael Fowler
  • Alicia Deng
  • Henry Dargie
  • Frances L Johnson

Detail Information

Publications18

  1. ncbi Computer applications in the interpretation of the exercise electrocardiogram
    E A Ashley
    Department of Cardiovascular Medicine, University of Oxford, Oxford Cardiac Center, England
    Sports Med 30:231-48. 2000
    ..These key features explain the pivotal role of the exercise test in the diagnostic, and increasingly prognostic, armoury of the cardiovascular clinician...
  2. ncbi Exercise testing in clinical medicine
    E A Ashley
    Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, UK
    Lancet 356:1592-7. 2000
    ..Brief, inexpensive, and done in most cases without the presence of a cardiologist, the exercise test offers the highest value for predictive accuracy of any of the non-invasive tests for coronary artery disease...
  3. ncbi Cardiac nitric oxide synthase 1 regulates basal and beta-adrenergic contractility in murine ventricular myocytes
    Euan A Ashley
    University Department of Cardiovascular Medicine, John Radcliffe Hospital, Oxford, UK
    Circulation 105:3011-6. 2002
    ..Here, we investigated the role of a type 1 NO synthase isoform (NOS1), which has been recently localized to the cardiac sarcoplasmic reticulum, in the regulation of basal and beta-adrenergic myocardial contraction...
  4. ncbi Diagnosing coronary artery disease in diabetic patients
    Euan A Ashley
    Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford, UK
    Diabetes Metab Res Rev 18:201-8. 2002
    ..Other diagnostic tools are considered, and recommendations are made with respect to screening asymptomatic diabetic patients for coronary artery disease...
  5. ncbi An evidence-based review of the resting electrocardiogram as a screening technique for heart disease
    E A Ashley
    Department of Cardiovascular Medicine, John Radcliffe Hospital, University of Oxford, UK
    Prog Cardiovasc Dis 44:55-67. 2001
    ..This could lead to a network of web-servers from which every patient's ECGs would be available. Such a situation could have a dramatic effect on the advisability of performing screening ECGs...
  6. ncbi Cardiac neuronal nitric oxide synthase isoform regulates myocardial contraction and calcium handling
    Claire E Sears
    Department of Cardiovascular Medicine, Oxford University, John Radcliffe Hospital, Oxford, OX3 9DU, UK
    Circ Res 92:e52-9. 2003
    ..The full text of this article is available at http://www.circresaha.org...
  7. pmc Nitric oxide control of cardiac function: is neuronal nitric oxide synthase a key component?
    Claire E Sears
    Department of Cardiovascular Medicine, University of Oxford, John Radcliffe Hospital, Oxford OX3 9DU, UK
    Philos Trans R Soc Lond B Biol Sci 359:1021-44. 2004
    ..Whether or not the role of nNOS carries implications for cardiovascular disease remains an intriguing possibility requiring future study...
  8. ncbi Prognostic value of heart rate increase at onset of exercise testing
    Nicholas J Leeper
    Stanford University Medical Center, Stanford University Medical School, Calif, USA
    Circulation 115:468-74. 2007
    ..Our aim was to evaluate the prognostic value of early heart rate parameters in patients referred for routine clinical treadmill testing...
  9. doi Ventricular arrhythmias during clinical treadmill testing and prognosis
    Frederick E Dewey
    Stanford University Medical School, Palo Alto, California, USA
    Arch Intern Med 168:225-34. 2008
    ..Therefore, we aimed to evaluate the clinical correlates and prognostic significance of exercise-associated premature ventricular complexes (PVCs) during and after exercise testing...
  10. doi Does size matter? Clinical applications of scaling cardiac size and function for body size
    Frederick E Dewey
    Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Circulation 117:2279-87. 2008
    ..Lack of appropriate consideration of body size in the evaluation of cardiovascular structure and function may adversely affect recognition and treatment of cardiovascular disease states in the adult patient...
  11. pmc Low-dose growth hormone is cardioprotective in uremia
    Ralph Rabkin
    Department of Medicine, Stanford University and Research Service, Veterans Administration Health Care System, Palo Alto, California 94304, USA
    J Am Soc Nephrol 19:1774-83. 2008
    ..In contrast, high-dosage GH worsened several of these variables. These results suggest that low-dosage GH may benefit the heart and possibly the carotid arteries in chronic renal failure...
  12. ncbi Magnetic resonance imaging of progressive cardiomyopathic changes in the db/db mouse
    Patrick Yue
    Division of Cardiovascular Medicine, Department of Medicine, Stanford University Medical Center, 300 Pasteur Drive, Stanford, CA 94305 5406, USA
    Am J Physiol Heart Circ Physiol 292:H2106-18. 2007
    ..In summary, as assessed by CMR, db/db mice develop characteristic structural and functional changes consistent with cardiomyopathy...
  13. ncbi Pathway analysis of coronary atherosclerosis
    Jennifer Y King
    Donald W Reynolds Cardiovascular Research Center, Division of Cardiovascular Medicine, Falk Cardiovascular Research Center, Stanford University, Stanford, California 94305, USA
    Physiol Genomics 23:103-18. 2005
    ....
  14. ncbi Signature patterns of gene expression in mouse atherosclerosis and their correlation to human coronary disease
    Raymond Tabibiazar
    Donald W Reynolds Cardiovascular Clinical Research Center, Division of Cardiovascular Medicine, Stanford, CA, USA
    Physiol Genomics 22:213-26. 2005
    ....
  15. pmc The endogenous peptide apelin potently improves cardiac contractility and reduces cardiac loading in vivo
    Euan A Ashley
    Donald W Reynolds Cardiovascular Research Center, Division of Cardiovascular Medicine, Stanford University, Stanford, CA 94305, USA
    Cardiovasc Res 65:73-82. 2005
    ..The endogenous peptide apelin is differentially regulated in cardiovascular disease but the nature of its role in cardiac function remains unclear...
  16. ncbi Mouse strain-specific differences in vascular wall gene expression and their relationship to vascular disease
    Raymond Tabibiazar
    Donald W Reynolds Cardiovascular Clinical Research Center, Division of Cardiovascular Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA
    Arterioscler Thromb Vasc Biol 25:302-8. 2005
    ..In this study, we sought to identify the genetic pathways that are differentially activated in the aortas of these mice...
  17. ncbi Novel role for the potent endogenous inotrope apelin in human cardiac dysfunction
    Mary M Chen
    Donald W Reynolds Cardiovascular Research Center, Division of Cardiovascular Medicine, Falk CVRC, Stanford University, 300 Pasteur Dr, Stanford, Calif 94305, USA
    Circulation 108:1432-9. 2003
    ..Apelin is among the most potent stimulators of cardiac contractility known. However, no physiological or pathological role for apelin-angiotensin receptor-like 1 (APJ) signaling has ever been described...
  18. pmc Apelin signaling antagonizes Ang II effects in mouse models of atherosclerosis
    Hyung J Chun
    Department of Medicine and Department of Anesthesiology, Stanford University School of Medicine, Stanford, California, USA
    J Clin Invest 118:3343-54. 2008
    ..Taken together, these findings indicate that apelin signaling can block Ang II actions in vascular disease by increasing NO production and inhibiting Ang II cellular signaling...