Research Topics
Species | J AshburnerSummaryAffiliation: University College London Country: UK Publications
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Detail Information
Publications
Why voxel-based morphometry should be usedJ Ashburner
The Wellcome Department of Cognitive Neurology, Institute of Neurology, Queen Square, London WC1N 3BG, United Kingdom
Neuroimage 14:1238-43. 2001..We first review the tenets of VBM, paying particular attention to the relationship between VBM and tensor-based morphometry. The last two sections of this response deal with the specific concerns raised by Dr. Bookstein...
A voxel-based morphometric study of ageing in 465 normal adult human brainsC D Good
Wellcome Department of Cognitive Neurology, Institute of Neurology, London, United Kingdom
Neuroimage 14:21-36. 2001..There was no interaction of age with sex for regionally specific effects. These results corroborate previous reports and indicate that VBM is a useful technique for studying structural brain correlates of ageing through life in humans...
Modeling geometric deformations in EPI time seriesJ L Andersson
The Wellcome Department of Cognitive Neurology, London, United Kingdom
Neuroimage 13:903-19. 2001..An experiment on a subject performing voluntary movements in the scanner yielded plausible estimates of the deformation fields and their application to "unwarp" the time series significantly reduced movement-related variance...
Learning- and expectation-related changes in the human brain during motor learningN Ramnani
Wellcome Department of Cognitive Neurology, Institute of Neurology, London WC1N 3BG, United Kingdom
J Neurophysiol 84:3026-35. 2000..The changes seen in the ipsilateral cerebellar cortex may be due either to the violations of sensory predictions, or to learning-related increases in the excitability of cerebellar neurons to presentations of the CS+...
Nonlinear spatial normalization using basis functionsJ Ashburner
Functional Imaging Laboratory, Wellcome Department of Cognitive Neurology, Institute of Neurology, London, United Kingdom
Hum Brain Mapp 7:254-66. 1999....
Frontal, midbrain and striatal dopaminergic function in early and advanced Parkinson's disease A 3D [(18)F]dopa-PET studyJ S Rakshi
MRC Cyclotron Unit, Hammersmith Hospital, The Wellcome Department of Cognitive Neurology, Institute of Neurology, London, UK
Brain 122:1637-50. 1999..This suggests, therefore, that Parkinson's disease is a monoaminergic neurodegenerative disorder...
Representation of the temporal envelope of sounds in the human brainA L Giraud
Wellcome Department of Cognitive Neurology, Institute of Neurology, London WC1N 3BG, United Kingdom
J Neurophysiol 84:1588-98. 2000....
Image registration using a symmetric prior--in three dimensionsJ Ashburner
The Wellcome Department of Cognitive Neurology, Institute of Neurology, London, United Kingdom
Hum Brain Mapp 9:212-25. 2000..e., warping brain A to brain B should not be different probablistically from warping B to A). A gradient descent algorithm is presented for estimating the optimum deformations...
Navigation-related structural change in the hippocampi of taxi driversE A Maguire
Wellcome Department of Cognitive Neurology, Institute of Neurology, University College London, Queen Square, London WC1N 3BG, United Kingdom
Proc Natl Acad Sci U S A 97:4398-403. 2000..It seems that there is a capacity for local plastic change in the structure of the healthy adult human brain in response to environmental demands...
Cerebral asymmetry and the effects of sex and handedness on brain structure: a voxel-based morphometric analysis of 465 normal adult human brainsC D Good
Wellcome Department of Cognitive Neurology, Institute of Neurology, Queen Square, London WC1N 3BG, United Kingdom
Neuroimage 14:685-700. 2001..Males had increased grey matter volume bilaterally in the mesial temporal lobes, entorhinal and perirhinal cortex, and in the anterior lobes of the cerebellum, but no regions of increased grey matter concentration...
A global estimator unbiased by local changesJ L Andersson
The Wellcome Department of Cognitive Neurology, London, United Kingdom
Neuroimage 13:1193-206. 2001..The advantage of the new estimator is that it is not informed of experimental design and relies only on general assumptions regarding the nature of the signal...
Assessing study-specific regional variations in fMRI signalB Lipschutz
The Wellcome Department of Cognitive Neurology, Institute of Neurology, Queen Square, London, WC1N 3BG, United Kingdom
Neuroimage 13:392-8. 2001..It requires only the functional data and can thus be applied post hoc and without any additional scans...
Learning arbitrary visuomotor associations: temporal dynamic of brain activityI Toni
Wellcome Department of Cognitive Neurology, Institute of Neurology, 12 Queen Square, London, WC1N 3BG, United Kingdom
Neuroimage 14:1048-57. 2001..These findings suggest the inferior temporal and the ventral prefrontal cortex are critical neural nodes for integrating perceptual information with executive processes...
Distributional assumptions in voxel-based morphometryC H Salmond
Developmental Cognitive Neuroscience Unit, Institute of Child Health, University College London, London, United Kingdom
Neuroimage 17:1027-30. 2002..This is despite the fact that conventional group comparisons appear to be robust, remaining valid even with no smoothing. The implications of the results for researchers using voxel-based morphometry are discussed...
Generative and recognition models for neuroanatomyK J Friston
The Wellcome Department of Imaging Neuroscience, University of London, Institute of Neurology, London, UK WC1N 3BG
Neuroimage 23:21-4. 2004
The role of the medial temporal lobe in autistic spectrum disordersC H Salmond
Developmental Cognitive Neuroscience Unit, Institute of Child Health, University College London, London, UK
Eur J Neurosci 22:764-72. 2005..The structural imaging data highlight abnormalities in several brain regions previously implicated in ASD, including the medial temporal lobes...
Diffusion-based spatial priors for imagingL M Harrison
The Wellcome Trust Centre for Neuroimaging, Institute of Neurology, University College London, 12 Queen Square, London, WC1N 3BG, UK
Neuroimage 38:677-95. 2007..Critically, this means adaptive smoothing becomes an integral part of estimation and inference. We illustrate the method using synthetic and real fMRI data...
Classical and Bayesian inference in neuroimaging: applicationsK J Friston
The Wellcome Department of Cognitive Neurology and The Institute of Cognitive Neuroscience, University College London, Queen Square, London, WC1N 3BG, United Kingdom
Neuroimage 16:484-512. 2002..We conclude with some general comments on Bayesian approaches to image analysis and on some unresolved issues...
Classical and Bayesian inference in neuroimaging: theoryK J Friston
The Wellcome Department of Imaging Neuroscience, The Gatsby Computational Neuroscience Unit, University College London, Queen Square, London, WC1N 3BG, United Kingdom
Neuroimage 16:465-83. 2002..Although diverse, all these estimation problems are accommodated by the PEB framework described in this paper...
Computational neuroanatomy: new perspectives for neuroradiologyC D Good
Wellcome Department of Cognitive Neurology, ION, UCL, London, UK
Rev Neurol (Paris) 157:797-806. 2001..This review will describe the methodology and clinical applications of these techniques...
Neural basis of an inherited speech and language disorderF Vargha-Khadem
Cognitive Neuroscience Unit, Institute of Child Health, University College London Medical School, Wolfson Centre, Mecklenbourgh Square, London WC1N 2AP, United Kingdom
Proc Natl Acad Sci U S A 95:12695-700. 1998....
MRI analysis of an inherited speech and language disorder: structural brain abnormalitiesK E Watkins
Developmental Cognitive Neuroscience Unit, Institute of Child Health, University College London Medical School, London, UK
Brain 125:465-78. 2002..These results thus provide further evidence of a relationship between the abnormal development of this nucleus and the impairments in oromotor control and articulation reported in the KE family...
The precision of anatomical normalization in the medial temporal lobe using spatial basis functionsC H Salmond
Developmental Cognitive Neuroscience Unit, Institute of Child Health, University College London, 30 Guilford Street, London WCIN 1EM, United Kingdom
Neuroimage 17:507-12. 2002..quot; The implications of our results, for users of voxel-based morphometry, are discussed...
Voxel-based morphometry of herpes simplex encephalitisD R Gitelman
Cognitive Neurology and Alzheimer's Disease Center, Department of Neurology, Northwestern University Medical School, Chicago, Illinois 60611, USA
Neuroimage 13:623-31. 2001..The results, while consistent with the well-known histopathology of the disease, also demonstrate potential difficulties with this method...
Voxel-wise analysis of diffusion tensor MRI improves the confidence of diagnosis of corticobasal degeneration non-invasivelyM Bozzali
Neuroimaging Laboratory, Santa Lucia Foundation, IRCCS, Via Ardeatina 306, 00179 Rome, Italy
Parkinsonism Relat Disord 14:436-9. 2008..The lateralized distribution of DT-MRI abnormalities was consistent with clinical features providing a substantial support to the diagnosis...
