Jeffrey K Aronson

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. doi request reprint Distinguishing hazards and harms, adverse drug effects and adverse drug reactions : implications for drug development, clinical trials, pharmacovigilance, biomarkers, and monitoring
    Jeffrey K Aronson
    Department of Primary Care Health Sciences, New Radcliffe House, Radcliffe Observatory Quarter, Woodstock Road, Oxford, OX2 6GG, UK
    Drug Saf 36:147-53. 2013
  2. pmc Balanced prescribing - principles and challenges
    Jeffrey K Aronson
    Department of Primary Care Health Sciences, University of Oxford, UK
    Br J Clin Pharmacol 74:566-72. 2012
  3. pmc Research priorities in biomarkers and surrogate end-points
    Jeffrey K Aronson
    British Pharmacological Society, Green Templeton College, Woodstock Road, Oxford OX2 6HG, UK
    Br J Clin Pharmacol 73:900-7. 2012
  4. pmc Finding a VOICE for UK clinical pharmacology
    Jeffrey K Aronson
    British Pharmacological Society, Green Templeton College, Woodstock Road, Oxford OX2 6HG, UK
    Br J Clin Pharmacol 73:843-5. 2012
  5. doi request reprint Defining 'surveillance' in drug safety
    Jeffrey K Aronson
    Department of Primary Health Care, University of Oxford, Oxford, UK
    Drug Saf 35:347-57. 2012
  6. doi request reprint Defining rewardable innovation in drug therapy
    Jeffrey K Aronson
    Department of Primary Health Care, University of Oxford, 23 38 Hythe Bridge Street, Oxford OX1 2ET, UK
    Nat Rev Drug Discov 11:253-4. 2012
  7. doi request reprint Preventability of drug-related harms - part II: proposed criteria, based on frameworks that classify adverse drug reactions
    Jeffrey K Aronson
    University of Oxford, Department of Primary Health Care, Oxford, UK
    Drug Saf 33:995-1002. 2010
  8. pmc A comparison of three different sources of data in assessing the frequencies of adverse reactions to amiodarone
    Yoon K Loke
    Department of Clinical Pharmacology, University of Oxford, Radcliffe Infirmary, Oxford OX2 6HE, UK
    Br J Clin Pharmacol 57:616-21. 2004
  9. doi request reprint A strategy for regulatory action when new adverse effects of a licensed product emerge
    Jeffrey K Aronson
    University Department of Primary Health Care, Headington, Oxford, UK
    Drug Saf 32:91-8. 2009
  10. pmc Medication errors: problems and recommendations from a consensus meeting
    Abha Agrawal
    Department of Primary Health Care, Rosemary Rue Building, Old Road Campus, Headington, Oxford OX3 7LF, UK
    Br J Clin Pharmacol 67:592-8. 2009

Detail Information

Publications25

  1. doi request reprint Distinguishing hazards and harms, adverse drug effects and adverse drug reactions : implications for drug development, clinical trials, pharmacovigilance, biomarkers, and monitoring
    Jeffrey K Aronson
    Department of Primary Care Health Sciences, New Radcliffe House, Radcliffe Observatory Quarter, Woodstock Road, Oxford, OX2 6GG, UK
    Drug Saf 36:147-53. 2013
    ....
  2. pmc Balanced prescribing - principles and challenges
    Jeffrey K Aronson
    Department of Primary Care Health Sciences, University of Oxford, UK
    Br J Clin Pharmacol 74:566-72. 2012
    ..Careful attention to all facets of prescribing can improve the chances of benefit, reduce the risks of adverse reactions and interactions, and enhance adherence to therapy...
  3. pmc Research priorities in biomarkers and surrogate end-points
    Jeffrey K Aronson
    British Pharmacological Society, Green Templeton College, Woodstock Road, Oxford OX2 6HG, UK
    Br J Clin Pharmacol 73:900-7. 2012
    ..A robust taxonomy is needed of the relations that link the pathophysiology of disease, the mechanisms of action of interventions and their adverse effects, the desired clinical outcomes, and the surrogate end-points that predict them...
  4. pmc Finding a VOICE for UK clinical pharmacology
    Jeffrey K Aronson
    British Pharmacological Society, Green Templeton College, Woodstock Road, Oxford OX2 6HG, UK
    Br J Clin Pharmacol 73:843-5. 2012
    ..g. through joint training programmes) are desirable. COVERAGE: Attention to neglected areas, such as general practice, paediatrics, obstetrics, geriatrics, anaesthetics, cancer, and immunology. EMISSARIES: Trainees to spread the word...
  5. doi request reprint Defining 'surveillance' in drug safety
    Jeffrey K Aronson
    Department of Primary Health Care, University of Oxford, Oxford, UK
    Drug Saf 35:347-57. 2012
    ....
  6. doi request reprint Defining rewardable innovation in drug therapy
    Jeffrey K Aronson
    Department of Primary Health Care, University of Oxford, 23 38 Hythe Bridge Street, Oxford OX1 2ET, UK
    Nat Rev Drug Discov 11:253-4. 2012
    ..Here, we propose a definition of innovation with respect to medicinal products, accompanied by a ranking of the importance of different types of innovativeness, with the aim of providing a basis for rewarding such innovation...
  7. doi request reprint Preventability of drug-related harms - part II: proposed criteria, based on frameworks that classify adverse drug reactions
    Jeffrey K Aronson
    University of Oxford, Department of Primary Health Care, Oxford, UK
    Drug Saf 33:995-1002. 2010
    ..Furthermore, when the reliability of these definitions has been examined they have been found to be imperfect...
  8. pmc A comparison of three different sources of data in assessing the frequencies of adverse reactions to amiodarone
    Yoon K Loke
    Department of Clinical Pharmacology, University of Oxford, Radcliffe Infirmary, Oxford OX2 6HE, UK
    Br J Clin Pharmacol 57:616-21. 2004
    ....
  9. doi request reprint A strategy for regulatory action when new adverse effects of a licensed product emerge
    Jeffrey K Aronson
    University Department of Primary Health Care, Headington, Oxford, UK
    Drug Saf 32:91-8. 2009
    ..Our proposed framework could also be useful in risk management planning during drug development...
  10. pmc Medication errors: problems and recommendations from a consensus meeting
    Abha Agrawal
    Department of Primary Health Care, Rosemary Rue Building, Old Road Campus, Headington, Oxford OX3 7LF, UK
    Br J Clin Pharmacol 67:592-8. 2009
    ..15. Avoidance of defensive reactions if patients mention symptoms resulting from medication errors...
  11. pmc Adverse drug reactions--no farewell to harms
    Jeffrey K Aronson
    University Department of Clinical Pharmacology, Radcliffe Infirmary, Woodstock Road, Oxford OX2 6HE, UK
    Br J Clin Pharmacol 63:131-5. 2007
  12. pmc The diagnosis of art: Caravaggio's jaundiced Bacchus
    Jeffrey K Aronson
    Department of Clinical Pharmacology, Radcliffe Infirmary, Woodstock Road, Oxford OX2 6HE, UK
    J R Soc Med 100:429-30. 2007
  13. doi request reprint Evaluation of pharmacological evidence for forensic purposes
    Jeffrey K Aronson
    University Department of Primary Health Care, Oxford, UK
    Int J Risk Saf Med 24:3-12. 2012
    ..Reports should be written in clear English and should not contain statements that rely on expertise that the expert does not possess...
  14. doi request reprint No surgical innovation without evaluation: the IDEAL recommendations
    Peter McCulloch
    Nuffield Department of Surgery, University of Oxford, Oxford, UK
    Lancet 374:1105-12. 2009
    ..Achievement of improved design, conduct, and reporting of surgical research will need concerted action by editors, funders of health care and research, regulatory bodies, and professional societies...
  15. ncbi request reprint Clarification of terminology in drug safety
    Jeffrey K Aronson
    Department of Clinical Pharmacology, Radcliffe Infirmary, Oxford, UK
    Drug Saf 28:851-70. 2005
    ..We hope that these definitions will lead to discussion that will allow a corpus of satisfactory definitions to be widely agreed...
  16. doi request reprint From prescription-only to over-the-counter medicines ('PoM to P'): time for an intermediate category
    Jeffrey K Aronson
    Department of Primary Health Care, University of Oxford, Headington, Oxford OX3 7LF, UK
    Br Med Bull 90:63-9. 2009
    ....
  17. doi request reprint Selected national pharmacovigilance websites: an analysis of contents
    Charlotte I S Barker
    Oxford University Clinical Academic Graduate School, Oxford, UK
    Drug Saf 35:141-8. 2012
    ..Aim: The aim of this study was to perform an exploratory survey of national pharmacovigilance websites and compare their contents...
  18. pmc Problems with using mechanisms to solve the problem of extrapolation
    Jeremy Howick
    Department of Primary Care Health Sciences, Centre for Evidence Based Medicine, University of Oxford, New Radcliffe House, Radcliffe Observatory Quarter, Woodstock Road, Oxford, OX2 6GG, UK
    Theor Med Bioeth 34:275-91. 2013
    ..At the same time, when the problems with mechanistic knowledge have been addressed, such knowledge can and should be used to mitigate (nothing can entirely solve) the problem of extrapolation. ..
  19. pmc What do clinical pharmacologists do? A questionnaire survey of senior UK clinical pharmacologists
    Jeffrey K Aronson
    British Pharmacological Society Green Templeton College, Woodstock Road, Oxford OX2 6HG, UK
    Br J Clin Pharmacol 73:161-9. 2012
    ..Many trainees therefore leave the discipline when they become consultants...
  20. ncbi request reprint Adverse drug reactions: keeping up to date
    Jeffrey K Aronson
    University Department of Clinical Pharmacology, Radcliffe Infirmary, Woodstock Road, Oxford OX2 6HE, UK
    Fundam Clin Pharmacol 16:49-56. 2002
    ..Systematic reviews are too few in number (only 1.25% of publications on adverse drug reactions cited in Side Effects of Drugs Annual); more are needed...
  21. pmc The diagnosis of art: Alice, the Duchess, Sir John Tenniel, foxgloves, and roses
    Jeffrey K Aronson
    Department of Clinical Pharmacology Radcliffe Infirmary, Woodstock Road, Oxford OX2 6HE, UK
    J R Soc Med 100:576-8. 2007
  22. pmc The diagnosis of art: Valentin le désossé and Ehlers-Danlos syndrome
    Jeffrey K Aronson
    Department of Clinical Pharmacology, Radcliffe Infirmary, Woodstock Road, Oxford OX2 6HE, UK
    J R Soc Med 100:193-4. 2007
  23. ncbi request reprint Unity from diversity: the evidential use of anecdotal reports of adverse drug reactions and interactions
    Jeffrey K Aronson
    Reader in Clinical Pharmacology, University Department of Clinical Pharmacology, Radcliffe Infirmary, Woodstock Road, Oxford OX2 6HE, UK
    J Eval Clin Pract 11:195-208. 2005
    ..One form of pattern recognition, teleoanalysis of data, should, when possible, include not only randomized controlled trials and observational studies, but also case series and anecdotal reports...
  24. ncbi request reprint Something new every day: defining innovation and innovativeness in drug therapy
    Jeffrey K Aronson
    Department of Primary Health Care, University of Oxford, Headington, Oxford, United Kingdom clinpharm ox ac uk
    J Ambul Care Manage 31:65-8. 2008
    ....
  25. pmc Medication errors: definitions and classification
    Jeffrey K Aronson
    Department of Primary Health Care, Oxford, UK
    Br J Clin Pharmacol 67:599-604. 2009
    ..6. Medication errors can be classified, invoking psychological theory, as knowledge-based mistakes, rule-based mistakes, action-based slips, and memory-based lapses. This classification informs preventive strategies...