W J Armitage
Affiliation: University of Bristol
- Protocols for thawing and cryoprotectant dilution of heart valvesW John Armitage
Bristol Heart Valve Bank, Department of Clinical Science, University of Bristol, Bristol, BS1 2LX, United Kingdom
Cryobiology 50:17-20. 2005..To reduce the time taken for thawing and removal of cryoprotectant from heart valves...
- Recovery of endothelial function after vitrification of cornea at -110 degrees CW John Armitage
Division of Ophthalmology, Bristol Eye Hospital, University of Bristol, Lower Maudlin Street, Bristol BS1 2LX, UK
Invest Ophthalmol Vis Sci 43:2160-4. 2002..To determine whether endothelial function is retained after ice-free cryopreservation of cornea by vitrification at -110 degrees C...
- The first successful full-thickness corneal transplant: a commentary on Eduard Zirm's landmark paper of 1906W J Armitage
Department of Clinical Science, University of Bristol, Bristol Eye Hospital, Bristol, UK
Br J Ophthalmol 90:1222-3. 2006
- Freezing monolayers of cells without gap junctionsW J Armitage
Division of Ophthalmology, Bristol Eye Hospital, University of Bristol, Lower Maudlin Street, BS1 2LX, Bristol, United Kingdom
Cryobiology 46:194-6. 2003..5 degrees C/min. This does not necessarily counter the suggestion that lack of gap junctions mitigates intracellular freezing as there is evidence that glycerol may itself promote intracellular freezing...
- Cryopreservation for corneal storageW John Armitage
Department of Clinical Science, University of Bristol, Bristol, UK
Dev Ophthalmol 43:63-9. 2009..Encouraging results have also been reported for cornea frozen using non-permeating cryoprotectants, which could lead to simpler methods of corneal cryopreservation...
- Risk of Creutzfeldt-Jakob disease transmission by ocular surgery and tissue transplantationW J Armitage
Academic Unit of Ophthalmology, University of Bristol, Bristol Eye Hospital, Lower Maudlin Street, Bristol BS1 2LX, UK
Eye (Lond) 23:1926-30. 2009..Use of appropriate cleaning and disinfection protocols and the ability to identify and quarantine instruments that may have been used on an infected patient are important safeguards...
- Predicting endothelial cell loss and long-term corneal graft survivalW John Armitage
Division of Ophthalmology, University of Bristol, Bristol, United Kingdom
Invest Ophthalmol Vis Sci 44:3326-31. 2003..To evaluate a biexponential decay model for describing the loss of corneal endothelial cells with age as well as the increased loss of cells after cataract surgery and penetrating keratoplasty...
- Antiviral treatment following penetrating keratoplasty for herpetic keratitisJ F B Goodfellow
Bristol Eye Hospital, Bristol, UK
Eye (Lond) 25:470-4. 2011..To assess the effect of antiviral treatment on corneal graft survival following penetrating keratoplasty for herpetic keratitis...
- Heart valve cryopreservation: protocol for addition of dimethyl sulphoxide and amelioration of putative amphotericin B toxicityVassilios Birtsas
Department of Clinical Sciences, Bristol Heart Valve Bank, University of Bristol, UK
Cryobiology 50:139-43. 2005..To investigate the need for stepwise addition of dimethyl sulphoxide to heart valves and amelioration of putative amphotericin B toxicity...
- Cryopreservation of cornea: a low cooling rate improves functional survival of endothelium after freezing and thawingCaroline Routledge
Division of Ophthalmology, University of Bristol, Bristol Eye Hospital, Lower Maudlin Street, Bristol BS1 2LX, UK
Cryobiology 46:277-83. 2003..To investigate the influence of low cooling rates on endothelial function and morphology of corneas frozen with propane-1,2-diol (PROH)...
- Integrity of epithelium and endothelium in organ-cultured human corneasJ M Crewe
Division of Ophthalmology, University of Bristol, Bristol Eye Hospital, Lower Maudlin Street, Bristol BS1 2LX, United Kingdom
Invest Ophthalmol Vis Sci 42:1757-61. 2001..Apoptosis was evident in epithelium but was observed rarely in the endothelium and then only after extended periods in organ culture...
- Outcomes of same-sizing versus oversizing donor trephines in keratoconic patients undergoing first penetrating keratoplastyPhilip D Jaycock
Bristol Eye Hospital, Bristol, United Kingdom
Ophthalmology 115:268-75. 2008..To investigate whether use of same-size donor and recipient trephines reduced myopia after penetrating keratoplasty for keratoconus...
- The visual and refractive outcomes of combined and sequential penetrating keratoplasty, cataract extraction, and intraocular lens insertionD Q Nguyen
Department of Ophthalmology, Bristol Eye Hospital, Bristol, UK
Eye (Lond) 23:1295-301. 2009....
- Long-term topical steroid treatment after penetrating keratoplasty in patients with pseudophakic bullous keratopathyAdam H Ross
Bristol Eye Hospital, Bristol, United Kingdom
Ophthalmology 116:2369-72. 2009..To assess the use of long-term topical corticosteroid treatment in patients with pseudophakic bullous keratopathy (PBK) after penetrating keratoplasty (PK)...
- Penetrating and deep anterior lamellar keratoplasty for keratoconus: a comparison of graft outcomes in the United kingdomMark N A Jones
NHS Blood and Transplant, Bristol, United Kingdom
Invest Ophthalmol Vis Sci 50:5625-9. 2009..To compare outcomes after penetrating keratoplasty (PK) and deep anterior lamellar keratoplasty (DALK) for keratoconus in the United Kingdom...
- A UK scheme for reporting serious adverse events and reactions associated with ocular tissue transplantationStephen Kaye
Ocular Tissue Advisory Group Audit Subgroup, Bristol, UK
Cell Tissue Bank 11:39-46. 2010..This vigilance model has been shown to be effective and could be applied in other fields of tissue or cell transplantation...
- Prospective, randomized clinical and endothelial evaluation of 2 storage times for cornea donor tissue in organ culture at 31 degrees CGilles Thuret
Department of Ophthalmology, University Hospital, and the Cornea Banks, Establissement Français du Sang of Saint Etienne, Saint Etienne, France
Arch Ophthalmol 121:442-50. 2003..To compare the endothelial and clinical outcome of penetrating keratoplasty with corneas stored in organ culture for up to 12 days (5-12 days; group 1) or more than 21 days (21-24 days; group 2)...
- Astigmatism and the impact of relaxing incisions after penetrating keratoplastyMargareta Claesson
Department of Ophthalmology, Sahlgrenska University Hospital, Molndal, Sweden
J Refract Surg 23:284-9. 2007..To determine the impact of relaxing incisions for correcting postoperative astigmatism following penetrating keratoplasty...
- Transplantation of ocular tissue from a donor with sporadic Creutzfeldt-Jakob diseaseAndrew B Tullo
Manchester Royal Eye Hospital, Manchester, UK
Clin Experiment Ophthalmol 34:645-9. 2006..We report an incident in the UK in 1997 in which both corneas and scleras from a donor, subsequently confirmed to have had sCJD, were transplanted. The final clinical outcome for two surviving recipients is still not yet known...
- Is directed donation misguided?Trevor Sherwin
Department of Ophthalmology, Faculty of Medical and Health Sciences, University of Auckland, Auckland, New Zealand
Clin Experiment Ophthalmol 32:5-8. 2004..In this Clinical Conundrum, six specialists delve into the ethical and practical issues surrounding directed donation of human organs and tissues with particular reference to its implications in the field of ophthalmology...