Kirit M Ardeshna
Affiliation: University College London
- The upregulation of CC chemokine receptor 7 and the increased migration of maturing dendritic cells to macrophage inflammatory protein 3beta and secondary lymphoid chemokine is mediated by the p38 stress-activated protein kinase pathwayKirit M Ardeshna
Department of Haematology, Royal Free and UCL Medical School, Guy s, King s, St Thomas School of Medicine, Rayne Institute, London, UK
Br J Haematol 119:826-9. 2002..These findings have implications for the mechanism of action of p38SAPK inhibitors, currently in use in clinical trials for patients with autoimmune diseases...
- Long-term effect of a watch and wait policy versus immediate systemic treatment for asymptomatic advanced-stage non-Hodgkin lymphoma: a randomised controlled trialK M Ardeshna
British National Lymphoma Investigation, CRC and UCL Cancer Trials Centre, London NW1 2DA, UK
Lancet 362:516-22. 2003....
- Rituximab in combination with CODOX-M/IVAC: a retrospective analysis of 23 cases of non-HIV related B-cell non-Hodgkin lymphoma with proliferation index >95%Sajir G Mohamedbhai
Department of Haematology, University College London Hospitals NHS Foundation Trust, UK
Br J Haematol 152:175-81. 2011..These results with R-CODOX-M/R-IVAC compare favourably with existing data using CODOX-M/IVAC and warrant further prospective studies. The potential pitfalls of PET-CT to assess response are highlighted...
- Conventional second-line salvage chemotherapy regimens are not warranted in patients with malignant lymphomas who have progressive disease after first-line salvage therapy regimensKirit M Ardeshna
Department of Haematology, University College London Hospitals, London, UK
Br J Haematol 130:363-72. 2005..This analysis indicates that patients with malignant lymphomas, who have PD on 1 degrees ST, are not rescued by subsequent salvage regimens. They should either be treated palliatively or novel approaches should be explored...
- Cardiac tamponade in Hodgkin lymphomaAndrew Retter
Department of Haematology, St Thomas NHS Trust, London, UK
Br J Haematol 138:2. 2007
- Hotel-based ambulatory care for complex cancer patients: a review of the University College London Hospital experienceJonathan Sive
Department of Haematology, University College London Hospital, London, UK
Leuk Lymphoma 53:2397-404. 2012..An ACU/hotel-based treatment model can be safely used for a wide variety of cancers and treatments, expanding hospital treatment capacity, and freeing up inpatient beds for those patients requiring them...
- Has single-agent rituximab replaced watch-and-wait for a patient with asymptomatic low-grade follicular lymphoma?Lisa Lowry
Department of Haematology, University College London Cancer Institute and University College Hospital, London, UK
Cancer J 18:390-5. 2012..Even without the longer-term survival data, this has reignited the debate over initial management in FL...
- Use of zidovudine and interferon alfa with chemotherapy improves survival in both acute and lymphoma subtypes of adult T-cell leukemia/lymphomaAndrew Hodson
National Centre for Human Retrovirology, St Mary s Hospital, Imperial College Healthcare National Health Service Trust, United Kingdom
J Clin Oncol 29:4696-701. 2011..Use of zidovudine (ZDV) and interferon alfa (IFN-α) has been associated with improved response rates in small studies and prolonged overall survival in leukemic ATLL subtypes in a recent meta-analysis...
- Etoposide, methylprednisolone, cytarabine and cisplatin successfully cytoreduces resistant myeloma patients and mobilizes them for transplant without adverse effectsShirley D'Sa
Department of Haematology, University College London Hospitals NHS Trust, London, UK
Br J Haematol 125:756-65. 2004..We conclude that ESHAP has acceptable toxicity and efficient stem cell mobilizing capability, effectively cytoreduced this chemoresistant group of patients, and did not appear to adversely affect transplant outcome...