Catherine Arden

Summary

Affiliation: University of Newcastle
Country: UK

Publications

  1. pmc Susceptibility of glucokinase-MODY mutants to inactivation by oxidative stress in pancreatic β-cells
    Kirsty S Cullen
    Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, U K
    Diabetes 60:3175-85. 2011
  2. pmc Elevated glucose represses liver glucokinase and induces its regulatory protein to safeguard hepatic phosphate homeostasis
    Catherine Arden
    Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, U K
    Diabetes 60:3110-20. 2011

Collaborators

  • Kirsty S Cullen
  • Loranne Agius
  • Franz M Matschinsky

Detail Information

Publications2

  1. pmc Susceptibility of glucokinase-MODY mutants to inactivation by oxidative stress in pancreatic β-cells
    Kirsty S Cullen
    Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, U K
    Diabetes 60:3175-85. 2011
    ..We tested the hypothesis that GK mutants that cause maturity-onset diabetes of the young (GK-MODY) show compromised activity and posttranslational regulation in β-cells...
  2. pmc Elevated glucose represses liver glucokinase and induces its regulatory protein to safeguard hepatic phosphate homeostasis
    Catherine Arden
    Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, U K
    Diabetes 60:3110-20. 2011
    ..The induction of hepatic glucose 6-phosphatase (G6pc) by glucose presents a paradox of glucose-induced glucose intolerance. We tested whether glucose regulation of liver gene expression is geared toward intracellular homeostasis...