Carl A Anderson

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. ncbi Evaluating the effects of imputation on the power, coverage, and cost efficiency of genome-wide SNP platforms
    Carl A Anderson
    The Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, OX3 7BN Oxford, UK
    Am J Hum Genet 83:112-9. 2008
  2. ncbi Estimation of variance components for age at menarche in twin families
    Carl A Anderson
    Genetic Epidemiology Group, Queensland Institute of Medical Research, Brisbane 4029, Australia
    Behav Genet 37:668-77. 2007
  3. ncbi Genome-wide association meta-analysis identifies new endometriosis risk loci
    Dale R Nyholt
    Queensland Institute of Medical Research, Brisbane, Queensland, Australia
    Nat Genet 44:1355-9. 2012
  4. ncbi Basic statistical analysis in genetic case-control studies
    Geraldine M Clarke
    Genetic and Genomic Epidemiology Unit, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK
    Nat Protoc 6:121-33. 2011
  5. ncbi Marker selection for genetic case-control association studies
    Fredrik H Pettersson
    Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK
    Nat Protoc 4:743-52. 2009
  6. ncbi Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship
    Carl A Anderson
    Genetic and Genomic Epidemiology Unit, Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, UK
    Gastroenterology 136:523-9.e3. 2009
  7. ncbi A genome-wide linkage scan for age at menarche in three populations of European descent
    Carl A Anderson
    Queensland Institute of Medical Research, Royal Brisbane Hospital, Queensland 4029, Australia
    J Clin Endocrinol Metab 93:3965-70. 2008
  8. ncbi Meta-analysis and imputation refines the association of 15q25 with smoking quantity
    Jason Z Liu
    Department of Statistics, University of Oxford, Oxford, UK
    Nat Genet 42:436-40. 2010
  9. ncbi Data quality control in genetic case-control association studies
    Carl A Anderson
    Genetic and Genomic Epidemiology Unit, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK
    Nat Protoc 5:1564-73. 2010
  10. ncbi Genome-wide association study identifies a locus at 7p15.2 associated with endometriosis
    Jodie N Painter
    Molecular Epidemiology, Queensland Institute of Medical Research, Herston, Queensland, Australia
    Nat Genet 43:51-4. 2011

Detail Information

Publications17

  1. ncbi Evaluating the effects of imputation on the power, coverage, and cost efficiency of genome-wide SNP platforms
    Carl A Anderson
    The Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, OX3 7BN Oxford, UK
    Am J Hum Genet 83:112-9. 2008
    ..Platforms consisting of around 1 million SNPs offer poor cost efficiency for SNP association in European populations...
  2. ncbi Estimation of variance components for age at menarche in twin families
    Carl A Anderson
    Genetic Epidemiology Group, Queensland Institute of Medical Research, Brisbane 4029, Australia
    Behav Genet 37:668-77. 2007
    ..50 and 0.54, and common environmental effects to be 0.31 and 0.29, respectively. We conclude that variation in AAM can be explained by additive genetic and common environmental components...
  3. ncbi Genome-wide association meta-analysis identifies new endometriosis risk loci
    Dale R Nyholt
    Queensland Institute of Medical Research, Brisbane, Queensland, Australia
    Nat Genet 44:1355-9. 2012
    ..8 × 10(-11)), indicating that many weakly associated SNPs represent true endometriosis risk loci and that risk prediction and future targeted disease therapy may be transferred across these populations...
  4. ncbi Basic statistical analysis in genetic case-control studies
    Geraldine M Clarke
    Genetic and Genomic Epidemiology Unit, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK
    Nat Protoc 6:121-33. 2011
    ..Study design, marker selection and quality control of case-control studies have also been discussed in earlier protocols. The protocol should take ~1 h to complete...
  5. ncbi Marker selection for genetic case-control association studies
    Fredrik H Pettersson
    Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK
    Nat Protoc 4:743-52. 2009
    ..Publicly available web-based resources are utilized to browse and retrieve data, and software, such as Haploview and Goldsurfer2, is applied to investigate LD and to select tagSNPs...
  6. ncbi Investigation of Crohn's disease risk loci in ulcerative colitis further defines their molecular relationship
    Carl A Anderson
    Genetic and Genomic Epidemiology Unit, Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford, UK
    Gastroenterology 136:523-9.e3. 2009
    ..Furthermore, the recently identified UC locus at ECM1 requires formal testing for association with CD...
  7. ncbi A genome-wide linkage scan for age at menarche in three populations of European descent
    Carl A Anderson
    Queensland Institute of Medical Research, Royal Brisbane Hospital, Queensland 4029, Australia
    J Clin Endocrinol Metab 93:3965-70. 2008
    ..Age at menarche (AAM) is an important trait both biologically and socially, a clearly defined event in female pubertal development, and has been associated with many clinically significant phenotypes...
  8. ncbi Meta-analysis and imputation refines the association of 15q25 with smoking quantity
    Jason Z Liu
    Department of Statistics, University of Oxford, Oxford, UK
    Nat Genet 42:436-40. 2010
    ..Our fine-mapping approach identified a SNP showing the highest significance, rs55853698, located within the promoter region of CHRNA5. Conditional analysis also identified a secondary locus (rs6495308) in CHRNA3...
  9. ncbi Data quality control in genetic case-control association studies
    Carl A Anderson
    Genetic and Genomic Epidemiology Unit, Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford, UK
    Nat Protoc 5:1564-73. 2010
    ..Issues concerning study design and marker selection in case-control studies have been discussed in our earlier protocols. This protocol, which is routinely used in our labs, should take approximately 8 h to complete...
  10. ncbi Genome-wide association study identifies a locus at 7p15.2 associated with endometriosis
    Jodie N Painter
    Molecular Epidemiology, Queensland Institute of Medical Research, Herston, Queensland, Australia
    Nat Genet 43:51-4. 2011
    ..4 × 10⁻⁹ (OR = 1.20, 95% CI 1.13-1.27) for 'all' endometriosis in our combined datasets of 5,586 cases and 9,331 controls. rs12700667 is located in an intergenic region upstream of the plausible candidate genes NFE2L3 and HOXA10...
  11. ncbi Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease
    Jeffrey C Barrett
    Bioinformatics and Statistical Genetics, Wellcome Trust Centre for Human Genetics, University of Oxford, Roosevelt Drive, Oxford OX3 7BN, UK
    Nat Genet 40:955-62. 2008
    ..The expanded molecular understanding of the basis of this disease offers promise for informed therapeutic development...
  12. ncbi Confirmation of the role of ATG16L1 as a Crohn's disease susceptibility gene
    J R Fraser Cummings
    Wellcome Trust Centre for Human Genetics, University of Oxford, Oxford OX3 7BN, UK
    Inflamm Bowel Dis 13:941-6. 2007
    ..The aims of the study were to replicate the association with CD, examine subphenotype associations and statistical interactions with CARD15, IL23R, and the IBD5 risk haplotype, as well as explore the association with UC...
  13. ncbi Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
    Miles Parkes
    Inflammatory Bowel Disease Research Group, Addenbrooke s Hospital, University of Cambridge, Cambridge CB2 2QQ, UK
    Nat Genet 39:830-2. 2007
    ..We obtained replication for the autophagy-inducing IRGM gene on chromosome 5q33.1 (replication P = 6.6 x 10(-4), combined P = 2.1 x 10(-10)) and for nine other loci, including NKX2-3, PTPN2 and gene deserts on chromosomes 1q and 5p13...
  14. ncbi Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease
    Sheila A Fisher
    Department of Medical and Molecular Genetics, King s College London School of Medicine, 8th Floor Guy s Tower, Guy s Hospital, London SE1 9RT, UK
    Nat Genet 40:710-2. 2008
    ..These data provide the first detailed illustration of the genetic relationship between these common inflammatory bowel diseases...
  15. ncbi Process characterization of powder blending by near-infrared spectroscopy: blend end-points and beyond
    Zhenqi Shi
    Graduate School of Pharmaceutical Sciences, Duquesne University, Pittsburgh, PA 15282, USA
    J Pharm Biomed Anal 47:738-45. 2008
    ....
  16. ncbi A genome-wide linkage study in families with major depression and co-morbid unexplained swelling
    Carl A Anderson
    Institute of Evolutionary Biology, University of Edinburgh, Edinburgh, UK
    Am J Med Genet B Neuropsychiatr Genet 147:356-62. 2008
    ....
  17. ncbi A simple linear regression method for quantitative trait loci linkage analysis with censored observations
    Carl A Anderson
    Institute of Evolutionary Biology, University of Edinburgh, Scotland
    Genetics 173:1735-45. 2006
    ..On the basis of linear regression methodology, the grouped linear regression model is computationally simple and fast and can be implemented readily in freely available statistical software...