Affiliation: University of Cambridge
- How the confocal laser scanning microscope entered biological researchW B Amos
MRC Laboratory of Molecular Biology, Cambridge, UK
Biol Cell 95:335-42. 2003..Lessons are pointed out from the unusual nature of the original funding and research environment. Attention is drawn to the slow adoption of the instrument in diagnostic medicine, despite promising applications...
- Lessons from the history of light microscopyB Amos
MRC Laboratory of Molecular Biology, Hills Road, Cambridge, CB2 2QH, UK
Nat Cell Biol 2:E151-2. 2000..The explorations that began in the 17th century are by no means complete, but who is carrying them forward now?..
- Re-evaluation of differential phase contrast (DPC) in a scanning laser microscope using a split detector as an alternative to differential interference contrast (DIC) opticsW B Amos
MRC Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK
J Microsc 210:166-75. 2003..DPC is also here found to need 20 times less laser power at the specimen than DIC...
- Microsatellite and trinucleotide-repeat evolution: evidence for mutational bias and different rates of evolution in different lineagesD C Rubinsztein
Department of Medical Genetics, Cambridge Institute for Medical Research, Addenbrooke s Hospital, UK
Philos Trans R Soc Lond B Biol Sci 354:1095-9. 1999..In addition, our experiments suggest that the rates of expansion of such sequences differ in related species...
- Multiphoton imagingB Amos
MRC Laboratory of Molecular Biology, Cambridge, United Kingdom
Curr Protoc Cytom . 2001..The usefulness of multiphoton imaging is critically discussed and compared with confocal. Details of laboratory setup are also included...