Varuna R Aluvihare
Affiliation: University of Cambridge
- Regulatory T cells mediate maternal tolerance to the fetusVaruna R Aluvihare
Medical Research Council, Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, United Kingdom
Nat Immunol 5:266-71. 2004..Their absence led to a failure of gestation due to immunological rejection of the fetus...
- Tolerance, suppression and the fetal allograftVaruna R Aluvihare
Laboratory of Molecular Biology, Medical Research Council, University of Cambridge, Hills Road, Cambridge, CB2 2QH, UK
J Mol Med (Berl) 83:88-96. 2005..We review the mechanisms that mediate materno-fetal tolerance, with particular emphasis on changes in regulatory T cell function during pregnancy and discuss their implications...
- The role of regulatory T cells in alloantigen toleranceVaruna R Aluvihare
Medical Research Council, Laboratory of Molecular Biology, Cambridge, UK
Immunol Rev 212:330-43. 2006..We review the function of Tregs from this perspective and propose that they may have evolved to promote tolerance to alloantigen in the context of pregnancy...