Claudio R Alonso

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi The molecular elements that underlie developmental evolution
    Claudio R Alonso
    Laboratory for Development and Evolution, Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
    Nat Rev Genet 6:709-15. 2005
  2. ncbi Fibronectin transcription in liver cells: promoter occupation and function in sinusoidal endothelial cells and hepatocytes
    Claudio R Alonso
    Laboratorio de Fisiologia y Biologia Molecular, Departamento de Ciencias Biologicas, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina
    Biochem Biophys Res Commun 295:1077-84. 2002
  3. ncbi Hox proteins: sculpting body parts by activating localized cell death
    Claudio R Alonso
    Laboratory for Development and Evolution, Department of Zoology, University of Cambridge, Downing Street, CB2 3EJ, Cambridge, UK
    Curr Biol 12:R776-8. 2002
  4. ncbi A Hox gene mutation that triggers nonsense-mediated RNA decay and affects alternative splicing during Drosophila development
    Claudio R Alonso
    Laboratory for Development and Evolution, Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
    Nucleic Acids Res 31:3873-80. 2003
  5. ncbi A slow RNA polymerase II affects alternative splicing in vivo
    Manuel De la Mata
    Laboratorio de Fisiologia y Biologia Molecular, Departamento de Fisiologia, Biologia Molecular y Celular, IFIBYNE CONICET, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Pabellon 2, Buenos Aires, Argentina
    Mol Cell 12:525-32. 2003
  6. ncbi Alternative splicing modulates Ubx protein function in Drosophila melanogaster
    Hilary C Reed
    Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK
    Genetics 184:745-58. 2010
  7. ncbi Genome-wide analysis of mRNA decay patterns during early Drosophila development
    Stefan Thomsen
    Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
    Genome Biol 11:R93. 2010
  8. ncbi Nonsense-mediated RNA decay: a molecular system micromanaging individual gene activities and suppressing genomic noise
    Claudio R Alonso
    Laboratory for Development and Evolution, Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
    Bioessays 27:463-6. 2005
  9. ncbi Drosophila miniature and dusky encode ZP proteins required for cytoskeletal reorganisation during wing morphogenesis
    Fernando Roch
    Laboratory for Development and Evolution, University Museum of Zoology, Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
    J Cell Sci 116:1199-207. 2003
  10. ncbi Regulation of fibronectin splicing in sinusoidal endothelial cells from normal or injured liver
    Ming Ling Chang
    Liver Center and Department of Medicine and Fetal Treatment Center, Department of Surgery, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 101:18093-8. 2004

Collaborators

Detail Information

Publications10

  1. ncbi The molecular elements that underlie developmental evolution
    Claudio R Alonso
    Laboratory for Development and Evolution, Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
    Nat Rev Genet 6:709-15. 2005
    ..We also explain why these alternative regulatory levels might have been neglected, and briefly discuss ways to test our hypothesis...
  2. ncbi Fibronectin transcription in liver cells: promoter occupation and function in sinusoidal endothelial cells and hepatocytes
    Claudio R Alonso
    Laboratorio de Fisiologia y Biologia Molecular, Departamento de Ciencias Biologicas, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Buenos Aires, Argentina
    Biochem Biophys Res Commun 295:1077-84. 2002
    ..These results establish the starting point to investigate the molecular basis of changes in transcriptional regulation of the FN gene involved in liver pathology...
  3. ncbi Hox proteins: sculpting body parts by activating localized cell death
    Claudio R Alonso
    Laboratory for Development and Evolution, Department of Zoology, University of Cambridge, Downing Street, CB2 3EJ, Cambridge, UK
    Curr Biol 12:R776-8. 2002
    ..A recent study reveals that the Drosophila Hox protein Deformed directly activates the cell-death-promoting gene reaper to maintain the boundaries between distinct head segments...
  4. ncbi A Hox gene mutation that triggers nonsense-mediated RNA decay and affects alternative splicing during Drosophila development
    Claudio R Alonso
    Laboratory for Development and Evolution, Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
    Nucleic Acids Res 31:3873-80. 2003
    ....
  5. ncbi A slow RNA polymerase II affects alternative splicing in vivo
    Manuel De la Mata
    Laboratorio de Fisiologia y Biologia Molecular, Departamento de Fisiologia, Biologia Molecular y Celular, IFIBYNE CONICET, Facultad de Ciencias Exactas y Naturales, Universidad de Buenos Aires, Ciudad Universitaria, Pabellon 2, Buenos Aires, Argentina
    Mol Cell 12:525-32. 2003
    ..These results provide a direct proof for the elongation control of alternative splicing in vivo...
  6. ncbi Alternative splicing modulates Ubx protein function in Drosophila melanogaster
    Hilary C Reed
    Department of Zoology, University of Cambridge, Cambridge CB2 3EJ, UK
    Genetics 184:745-58. 2010
    ..Since other Hox genes also produce splicing isoforms affecting similar protein domains, we suggest that alternative splicing may represent an underestimated regulatory system modulating Hox gene specificity during fly development...
  7. ncbi Genome-wide analysis of mRNA decay patterns during early Drosophila development
    Stefan Thomsen
    Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
    Genome Biol 11:R93. 2010
    ....
  8. ncbi Nonsense-mediated RNA decay: a molecular system micromanaging individual gene activities and suppressing genomic noise
    Claudio R Alonso
    Laboratory for Development and Evolution, Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
    Bioessays 27:463-6. 2005
    ..These findings support the notion that NMD is a high profile post-transcriptional mechanism micromanaging the activity of multiple gene batteries and suppressing the expression of genetic remnants...
  9. ncbi Drosophila miniature and dusky encode ZP proteins required for cytoskeletal reorganisation during wing morphogenesis
    Fernando Roch
    Laboratory for Development and Evolution, University Museum of Zoology, Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK
    J Cell Sci 116:1199-207. 2003
    ..We propose that Min and Dusky form a novel subfamily within the ZP domain proteins and are specifically involved in the interactions between the apical membrane, the cytoskeleton and the forming cuticle...
  10. ncbi Regulation of fibronectin splicing in sinusoidal endothelial cells from normal or injured liver
    Ming Ling Chang
    Liver Center and Department of Medicine and Fetal Treatment Center, Department of Surgery, University of California, San Francisco, CA 94143, USA
    Proc Natl Acad Sci U S A 101:18093-8. 2004
    ..The data suggest that TGFbeta modifies the spliceosome, if not through its known signaling intermediates, then through the products of genes regulated by this cytokine...