T Allers

Summary

Affiliation: University of Nottingham
Country: UK

Publications

  1. doi request reprint Swapping genes to survive - a new role for archaeal type IV pili
    Thorsten Allers
    School of Biology, University of Nottingham, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Mol Microbiol 82:789-91. 2011
  2. pmc Overexpression and purification of halophilic proteins in Haloferax volcanii
    Thorsten Allers
    Institute of Genetics, School of Biology, University of Nottingham, Queen s Medical Centre, Nottingham, UK
    Bioeng Bugs 1:288-90. 2010
  3. pmc Improved strains and plasmid vectors for conditional overexpression of His-tagged proteins in Haloferax volcanii
    Thorsten Allers
    Institute of Genetics, School of Biology, University of Nottingham, Queen s Medical Centre, Nottingham NG7 2UH, United Kingdom
    Appl Environ Microbiol 76:1759-69. 2010
  4. ncbi request reprint Genetic analysis of homologous recombination in Archaea: Haloferax volcanii as a model organism
    T Allers
    Institute of Genetics, University of Nottingham, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Biochem Soc Trans 31:706-10. 2003
  5. pmc Development of additional selectable markers for the halophilic archaeon Haloferax volcanii based on the leuB and trpA genes
    Thorsten Allers
    Institute of Genetics, University of Nottingham, Queen s Medical Centre, Nottingham NG7 2UH, United Kingdom
    Appl Environ Microbiol 70:943-53. 2004
  6. ncbi request reprint Archaeal genetics - the third way
    Thorsten Allers
    Institute of Genetics, University of Nottingham, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Nat Rev Genet 6:58-73. 2005
  7. ncbi request reprint Interactions of RadB, a DNA repair protein in archaea, with DNA and ATP
    Colin P Guy
    Institute of Genetics School of Biology, University of Nottingham, Queen s Medical Centre, Nottingham NG7 2UH, UK
    J Mol Biol 358:46-56. 2006
  8. doi request reprint RecA family proteins in archaea: RadA and its cousins
    Sam Haldenby
    Institute of Genetics, School of Biology, University of Nottingham, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Biochem Soc Trans 37:102-7. 2009
  9. doi request reprint The archaeal Xpf/Mus81/FANCM homolog Hef and the Holliday junction resolvase Hjc define alternative pathways that are essential for cell viability in Haloferax volcanii
    Roxane Lestini
    Institute of Genetics, School of Biology, University of Nottingham, Queen s Medical Centre, Nottingham, United Kingdom
    DNA Repair (Amst) 9:994-1002. 2010
  10. pmc Mre11-Rad50 promotes rapid repair of DNA damage in the polyploid archaeon Haloferax volcanii by restraining homologous recombination
    Stéphane Delmas
    Institute of Genetics, School of Biology, University of Nottingham, Queen s Medical Centre, Nottingham, United Kingdom
    PLoS Genet 5:e1000552. 2009

Collaborators

Detail Information

Publications14

  1. doi request reprint Swapping genes to survive - a new role for archaeal type IV pili
    Thorsten Allers
    School of Biology, University of Nottingham, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Mol Microbiol 82:789-91. 2011
    ..This work has defined a new role for type IV pili in both the transfer of genes within species and the recovery from UV-induced DNA damage...
  2. pmc Overexpression and purification of halophilic proteins in Haloferax volcanii
    Thorsten Allers
    Institute of Genetics, School of Biology, University of Nottingham, Queen s Medical Centre, Nottingham, UK
    Bioeng Bugs 1:288-90. 2010
    ..We have harnessed the sophisticated genetic tools available for the haloarchaeon Haloferax volcanii, to develop a system for the overexpression and purification of halophilic proteins under native conditions...
  3. pmc Improved strains and plasmid vectors for conditional overexpression of His-tagged proteins in Haloferax volcanii
    Thorsten Allers
    Institute of Genetics, School of Biology, University of Nottingham, Queen s Medical Centre, Nottingham NG7 2UH, United Kingdom
    Appl Environ Microbiol 76:1759-69. 2010
    ..We also deleted the mrr restriction endonuclease gene, thereby allowing direct transformation without the need to passage DNA through an Escherichia coli dam mutant...
  4. ncbi request reprint Genetic analysis of homologous recombination in Archaea: Haloferax volcanii as a model organism
    T Allers
    Institute of Genetics, University of Nottingham, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Biochem Soc Trans 31:706-10. 2003
    ..We are developing such systems using Haloferax volcanii as a model organism, as it can be cultivated in the laboratory with ease and offers great potential for establishing tractable and informative genetic systems...
  5. pmc Development of additional selectable markers for the halophilic archaeon Haloferax volcanii based on the leuB and trpA genes
    Thorsten Allers
    Institute of Genetics, University of Nottingham, Queen s Medical Centre, Nottingham NG7 2UH, United Kingdom
    Appl Environ Microbiol 70:943-53. 2004
    ..We constructed both integrative and replicative plasmids carrying the leuB or trpA gene under control of a constitutive promoter. The use of these selectable markers in deletion of the lhr gene of H. volcanii is described...
  6. ncbi request reprint Archaeal genetics - the third way
    Thorsten Allers
    Institute of Genetics, University of Nottingham, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Nat Rev Genet 6:58-73. 2005
    ..It is time for geneticists to start asking fundamental questions about our distant relatives...
  7. ncbi request reprint Interactions of RadB, a DNA repair protein in archaea, with DNA and ATP
    Colin P Guy
    Institute of Genetics School of Biology, University of Nottingham, Queen s Medical Centre, Nottingham NG7 2UH, UK
    J Mol Biol 358:46-56. 2006
    ..ATP-induced conformational change in RadB may explain previous reports that RadB controls Holliday junction resolution by Hjc, depending on the presence or the absence of ATP...
  8. doi request reprint RecA family proteins in archaea: RadA and its cousins
    Sam Haldenby
    Institute of Genetics, School of Biology, University of Nottingham, Queen s Medical Centre, Nottingham NG7 2UH, UK
    Biochem Soc Trans 37:102-7. 2009
    ..On the basis of phylogenetic analysis, we propose that a family of archaeal proteins with a single RecA domain, which are currently annotated as KaiC, be renamed aRadC...
  9. doi request reprint The archaeal Xpf/Mus81/FANCM homolog Hef and the Holliday junction resolvase Hjc define alternative pathways that are essential for cell viability in Haloferax volcanii
    Roxane Lestini
    Institute of Genetics, School of Biology, University of Nottingham, Queen s Medical Centre, Nottingham, United Kingdom
    DNA Repair (Amst) 9:994-1002. 2010
    ..We propose that Hef and Hjc provide alternative means to restart stalled DNA replication forks...
  10. pmc Mre11-Rad50 promotes rapid repair of DNA damage in the polyploid archaeon Haloferax volcanii by restraining homologous recombination
    Stéphane Delmas
    Institute of Genetics, School of Biology, University of Nottingham, Queen s Medical Centre, Nottingham, United Kingdom
    PLoS Genet 5:e1000552. 2009
    ..Our results suggest that recombination might be similarly repressed in other polyploid organisms and at repetitive sequences in haploid and diploid species...
  11. pmc Infrequent co-conversion of markers flanking a meiotic recombination initiation site in Saccharomyces cerevisiae
    Lea Jessop
    Center for Cancer Research, National Cancer Institute, Bethesda, Maryland 20892, USA
    Genetics 169:1353-67. 2005
    ..One consequence of this asymmetry is the preferential concentration of crossovers in the vicinity of the initiating DSB...
  12. ncbi request reprint Characterization of a tightly controlled promoter of the halophilic archaeon Haloferax volcanii and its use in the analysis of the essential cct1 gene
    Andrew Large
    School of Biosciences, The University of Birmingham, Edgbaston B15 2TT, UK
    Mol Microbiol 66:1092-106. 2007
    ..To demonstrate this, we used the promoter to follow the consequences of depletion of the essential chaperonin protein CCT1, and to determine the ability of heterologous CCT proteins to function in H. volcanii...
  13. pmc Genetic and physical mapping of DNA replication origins in Haloferax volcanii
    Cedric Norais
    Institut de Genetique et Microbiologie, Universite Paris Sud, Orsay, France
    PLoS Genet 3:e77. 2007
    ..Our observations also suggest that H. volcanii is an ideal organism for studying how replication of four replicons is regulated in the context of the archaeal cell cycle...
  14. pmc Maturation of the 5S rRNA 5' end is catalyzed in vitro by the endonuclease tRNase Z in the archaeon H. volcanii
    Annette Hölzle
    Molekulare Botanik, Universitat Ulm, 89069 Ulm, Germany
    RNA 14:928-37. 2008
    ..Knock out of the tRNase Z gene in Haloferax volcanii is lethal, showing that the protein is essential for the cell...