Sarah Aldred

Summary

Affiliation: University of Birmingham
Country: UK

Publications

  1. ncbi request reprint Decreased dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) concentrations in plasma of Alzheimer's disease (AD) patients
    Sarah Aldred
    School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, Birmingham, UK
    Arch Gerontol Geriatr 51:e16-8. 2010
  2. ncbi request reprint The use of proteomics for the assessment of clinical samples in research
    Sarah Aldred
    School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Clin Biochem 37:943-52. 2004
  3. ncbi request reprint A moderate intensity exercise program did not increase the oxidative stress in older adults
    Sarah Aldred
    School of Sport and Exercise Sciences, College of Life and Environmental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Arch Gerontol Geriatr 53:350-3. 2011
  4. ncbi request reprint Oxidative and nitrative changes seen in lipoproteins following exercise
    Sarah Aldred
    School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Atherosclerosis 192:1-8. 2007
  5. doi request reprint The effect of steady state exercise on circulating human IgE and IgG in young healthy volunteers with known allergy
    Sarah Aldred
    School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom
    J Sci Med Sport 13:16-9. 2010
  6. doi request reprint Increased low-density lipoprotein oxidation, but not total plasma protein oxidation, in Alzheimer's disease
    Sarah Aldred
    School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Clin Biochem 43:267-71. 2010
  7. doi request reprint Assessment of oxidative stress in lymphocytes with exercise
    James E Turner
    School of Sport and Exercise Sciences, The University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK
    J Appl Physiol (1985) 111:206-11. 2011
  8. doi request reprint Eccentric-exercise induced inflammation attenuates the vascular responses to mental stress
    Nicola J Paine
    School of Sport and Exercise Sciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom
    Brain Behav Immun 30:133-42. 2013
  9. ncbi request reprint Prolonged depletion of antioxidant capacity after ultraendurance exercise
    James E Turner
    School of Sport and Exercise Sciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, United Kingdom
    Med Sci Sports Exerc 43:1770-6. 2011
  10. doi request reprint Measurement of exercise-induced oxidative stress in lymphocytes
    James E Turner
    School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK
    Biochem Soc Trans 39:1299-304. 2011

Detail Information

Publications21

  1. ncbi request reprint Decreased dehydroepiandrosterone (DHEA) and dehydroepiandrosterone sulfate (DHEAS) concentrations in plasma of Alzheimer's disease (AD) patients
    Sarah Aldred
    School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, Birmingham, UK
    Arch Gerontol Geriatr 51:e16-8. 2010
    ..635 in controls and 0.467 in AD, p<or=0.01). This study highlighted a measurable difference in DHEA and DHEAS concentrations in plasma from a large cohort of patients suffering from AD when compared to age-matched controls...
  2. ncbi request reprint The use of proteomics for the assessment of clinical samples in research
    Sarah Aldred
    School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Clin Biochem 37:943-52. 2004
    ..This review aims to summarise the findings of studies that have used proteomic research methods to analyse samples from clinical studies and to assess the impact that proteomic techniques have had in assessing clinical samples...
  3. ncbi request reprint A moderate intensity exercise program did not increase the oxidative stress in older adults
    Sarah Aldred
    School of Sport and Exercise Sciences, College of Life and Environmental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Arch Gerontol Geriatr 53:350-3. 2011
    ..Exercise at this intensity was not harmful and did not increase risk factors for diseases associated with oxidative stress in the participants of the study...
  4. ncbi request reprint Oxidative and nitrative changes seen in lipoproteins following exercise
    Sarah Aldred
    School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Atherosclerosis 192:1-8. 2007
    ..This review aims to summarise the studies investigating the effect of exercise on lipoprotein oxidation and nitration, and highlight areas in need of future research...
  5. doi request reprint The effect of steady state exercise on circulating human IgE and IgG in young healthy volunteers with known allergy
    Sarah Aldred
    School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, United Kingdom
    J Sci Med Sport 13:16-9. 2010
    ..Acute steady state moderate exercise significantly altered circulating IgE concentrations in volunteers with known allergy, while IgE concentrations in non-allergy sufferers did not change...
  6. doi request reprint Increased low-density lipoprotein oxidation, but not total plasma protein oxidation, in Alzheimer's disease
    Sarah Aldred
    School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Clin Biochem 43:267-71. 2010
    ..In the overlap of biochemical processes which have been identified in AD and VaD, oxidative stress is believed to contribute to the numerous pathologies of both dementias...
  7. doi request reprint Assessment of oxidative stress in lymphocytes with exercise
    James E Turner
    School of Sport and Exercise Sciences, The University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK
    J Appl Physiol (1985) 111:206-11. 2011
    ..Thus vigorous exercise resulted in a transient increase in lymphocyte oxidative stress. Results suggest this was unrelated to the alterations in the cellular composition of peripheral blood...
  8. doi request reprint Eccentric-exercise induced inflammation attenuates the vascular responses to mental stress
    Nicola J Paine
    School of Sport and Exercise Sciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham B15 2TT, United Kingdom
    Brain Behav Immun 30:133-42. 2013
    ..The observed impairment in vascular responses to stress associated with increased levels of inflammation suggests a mechanism through which inflammation might increase the risk for MI...
  9. ncbi request reprint Prolonged depletion of antioxidant capacity after ultraendurance exercise
    James E Turner
    School of Sport and Exercise Sciences, College of Life and Environmental Sciences, University of Birmingham, Birmingham, United Kingdom
    Med Sci Sports Exerc 43:1770-6. 2011
    ..The purpose of this study was to examine the short- and long-term (up to 1 month) effects of an ultraendurance running event on redox homeostasis...
  10. doi request reprint Measurement of exercise-induced oxidative stress in lymphocytes
    James E Turner
    School of Immunity and Infection, College of Medical and Dental Sciences, University of Birmingham, Birmingham B15 2TT, UK
    Biochem Soc Trans 39:1299-304. 2011
    ..The aim of the present review is to raise awareness of interpretational issues related to the assessment of oxidative stress in lymphocytes with exercise and to address the relevance of lymphocyte subset phenotyping in these contexts...
  11. doi request reprint Plasma levels of complement 4a protein are increased in Alzheimer's disease
    Stuart Bennett
    School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Alzheimer Dis Assoc Disord 26:329-34. 2012
    ..These data suggest that inflammatory processes, which have been shown to be involved in AD pathology in the brain, are also present in plasma...
  12. ncbi request reprint Altered DHEA and DHEAS response to exercise in healthy older adults
    Sarah Aldred
    School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, UK
    J Aging Phys Act 17:77-88. 2009
    ..Participants with higher DHEA postexercise had lower LDL protein carbonyl concentrations (Pearson's coefficient -.409, p < .05)...
  13. doi request reprint Oxidative stress in vascular dementia and Alzheimer's disease: a common pathology
    Stuart Bennett
    School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, Birmingham, UK
    J Alzheimers Dis 17:245-57. 2009
    ..We propose that the majority of cases share a vascular pathology and that oxidative stress is central to this common pathology...
  14. ncbi request reprint Fat supplementation, health, and endurance performance
    Asker E Jeukendrup
    Human Performance Laboratory, School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, Birmingham, United Kingdom
    Nutrition 20:678-88. 2004
    ..Most studies have not found any evidence for a beneficial effect of conjugated linoleic acid...
  15. pmc Rudimentary signs of immunosenescence in Cytomegalovirus-seropositive healthy young adults
    James E Turner
    School of Sport and Exercise Sciences, University of Birmingham, Birmingham, UK
    Age (Dordr) 36:287-97. 2014
    ..05). This study observed marked changes in the immune profile of young adults infected with CMV, suggesting that this virus may underlie rudimentary aspects of immunosenescence even in a chronologically young population. ..
  16. pmc The interactions of oxidative stress and inflammation with vascular dysfunction in ageing: the vascular health triad
    Alex J Wadley
    School of Sport and Exercise Sciences, The University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK
    Age (Dordr) 35:705-18. 2013
    ..We review evidence suggesting that exercise may ameliorate the age-related decline in vascular function, through reductions in both oxidative stress and inflammation...
  17. ncbi request reprint Alpha tocopherol supplementation elevates plasma apolipoprotein A1 isoforms in normal healthy subjects
    Sarah Aldred
    Life and Health Sciences, Aston University, Birmingham, UK
    Proteomics 6:1695-703. 2006
    ..01 after 28 days supplementation with 268 mg AT/day). These data demonstrate the time and dose sensitivity of the plasma proteome to AT supplementation...
  18. doi request reprint Latent cytomegalovirus infection amplifies CD8 T-lymphocyte mobilisation and egress in response to exercise
    James E Turner
    School of Sport and Exercise Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Brain Behav Immun 24:1362-70. 2010
    ..This is the first study to demonstrate that infection history is a determinant of immune system responses to exercise...
  19. ncbi request reprint Three months of moderate-intensity exercise reduced plasma 3-nitrotyrosine in rheumatoid arthritis patients
    Alex J Wadley
    School of Sport, Exercise and Rehabilitation Sciences, College of Life and Environmental Sciences, University of Birmingham, Edgbaston, Birmingham, B15 2TT, UK
    Eur J Appl Physiol 114:1483-92. 2014
    ..This study investigated the effect of exercise on markers of oxidative stress in RA, following acute exercise and a period of exercise training...
  20. doi request reprint Influence of menstrual cycle phase on muscle metaboreflex control of cardiac baroreflex sensitivity, heart rate and blood pressure in humans
    Doreen Hartwich
    School of Sport and Exercise Sciences, College of Life and Environmental Sciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, UK
    Exp Physiol 98:220-32. 2013
    ..These data indicate that endogenous fluctuations in oestrogen between the EF and LF phases of the menstrual cycle do not influence muscle metaboreflex control of cBRS, BP or HR in young women...
  21. ncbi request reprint Plasma antioxidant status, immunoglobulin g oxidation and lipid peroxidation in demented patients: relevance to Alzheimer disease and vascular dementia
    M Cristina Polidori
    Institute of Biochemistry and Molecular Biology I, Heinrich Heine University, Dusseldorf, Germany
    Dement Geriatr Cogn Disord 18:265-70. 2004
    ..This might be relevant to the pathophysiology of dementing disorders, particularly in light of the recently suggested importance of the vascular component in AD development...