S F Ahmed

Summary

Affiliation: University of Glasgow
Country: UK

Publications

  1. doi request reprint The concordance between serum anti-Mullerian hormone and testosterone concentrations depends on duration of hCG stimulation in boys undergoing investigation of gonadal function
    S F Ahmed
    Department of Child Health, Royal Hospital for Sick Children, Glasgow, UK
    Clin Endocrinol (Oxf) 72:814-9. 2010
  2. doi request reprint Secondary osteoporosis
    S F Ahmed
    Bone and Endocrine Research Group, Department of Child Health, University of Glasgow, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK
    Endocr Dev 16:170-90. 2009
  3. doi request reprint The European disorder of sex development registry: a virtual research environment
    S F Ahmed
    Developmental Endocrinology Research Group, Royal Hospital for Sick Children, Glasgow, UK
    Sex Dev 4:192-8. 2010
  4. doi request reprint Investigation and initial management of ambiguous genitalia
    S Faisal Ahmed
    Department of Child Health, Royal Hospital for Sick Children, University of Glasgow, Yorkhill, Glasgow G3 8SJ, United Kingdom
    Best Pract Res Clin Endocrinol Metab 24:197-218. 2010
  5. ncbi request reprint Facilitating and understanding the family's choice of injection device for growth hormone therapy by using conjoint analysis
    S F Ahmed
    Department of Child Health, Royal Hospital for Sick Children, Yorkhill, Glasgow G3 8SJ, UK
    Arch Dis Child 93:110-4. 2008
  6. doi request reprint Recent trends and clinical features of childhood vitamin D deficiency presenting to a children's hospital in Glasgow
    S F Ahmed
    Department of Child Health, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK
    Arch Dis Child 96:694-6. 2011
  7. doi request reprint The effect of GH and IGF1 on linear growth and skeletal development and their modulation by SOCS proteins
    S F Ahmed
    Developmental Endocrinology Research Group, Division of Developmental Medicine, Department of Child Health, Royal Hospital for Sick Children, University of Glasgow, Yorkhill, Glasgow G3 8SJ, UK
    J Endocrinol 206:249-59. 2010
  8. ncbi request reprint The effects of recombinant human growth hormone on linear growth in children with Crohn's disease and short stature
    S C Wong
    Bone and Endocrine Research Group, Royal Hospital for Sick Children, Glasgow, UK
    J Pediatr Endocrinol Metab 20:1315-24. 2007
  9. doi request reprint Pathophysiology and management of abnormal growth in children with chronic inflammatory bowel disease
    S F Ahmed
    Royal Hospital for Sick Children, University of Glasgow, Glasgow, UK
    World Rev Nutr Diet 106:142-8. 2013
  10. ncbi request reprint Changes in quantitative ultrasound in infants born at less than 32 weeks' gestation over the first 2 years of life: influence of clinical and biochemical changes
    H McDevitt
    Bone and Endocrine Research Group, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK
    Calcif Tissue Int 81:263-9. 2007

Collaborators

Detail Information

Publications58

  1. doi request reprint The concordance between serum anti-Mullerian hormone and testosterone concentrations depends on duration of hCG stimulation in boys undergoing investigation of gonadal function
    S F Ahmed
    Department of Child Health, Royal Hospital for Sick Children, Glasgow, UK
    Clin Endocrinol (Oxf) 72:814-9. 2010
    ..In boys undergoing investigation of gonadal function, the relationship between a single measurement of serum anti-Mullerian hormone (AMH) and hCG stimulated serum testosterone is unclear...
  2. doi request reprint Secondary osteoporosis
    S F Ahmed
    Bone and Endocrine Research Group, Department of Child Health, University of Glasgow, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK
    Endocr Dev 16:170-90. 2009
    ..If this is not possible, the use of bone sparing drugs such as the bisphosphonates may be necessary whilst ensuring that attention is paid to optimising calcium and vitamin D intake and encouraging exercise and mobility...
  3. doi request reprint The European disorder of sex development registry: a virtual research environment
    S F Ahmed
    Developmental Endocrinology Research Group, Royal Hospital for Sick Children, Glasgow, UK
    Sex Dev 4:192-8. 2010
    ....
  4. doi request reprint Investigation and initial management of ambiguous genitalia
    S Faisal Ahmed
    Department of Child Health, Royal Hospital for Sick Children, University of Glasgow, Yorkhill, Glasgow G3 8SJ, United Kingdom
    Best Pract Res Clin Endocrinol Metab 24:197-218. 2010
    ..A thorough knowledge of the underlying pathophysiology and the strengths and weaknesses of the investigative tools that are available for reaching a diagnosis is crucial...
  5. ncbi request reprint Facilitating and understanding the family's choice of injection device for growth hormone therapy by using conjoint analysis
    S F Ahmed
    Department of Child Health, Royal Hospital for Sick Children, Yorkhill, Glasgow G3 8SJ, UK
    Arch Dis Child 93:110-4. 2008
    ..Conjoint analysis involves the measurement of consumer preferences between choice alternatives...
  6. doi request reprint Recent trends and clinical features of childhood vitamin D deficiency presenting to a children's hospital in Glasgow
    S F Ahmed
    Department of Child Health, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK
    Arch Dis Child 96:694-6. 2011
    ..The incidence of vitamin D deficiency is unclear in the context of continuing demographic changes and the introduction of new public health measures...
  7. doi request reprint The effect of GH and IGF1 on linear growth and skeletal development and their modulation by SOCS proteins
    S F Ahmed
    Developmental Endocrinology Research Group, Division of Developmental Medicine, Department of Child Health, Royal Hospital for Sick Children, University of Glasgow, Yorkhill, Glasgow G3 8SJ, UK
    J Endocrinol 206:249-59. 2010
    ..Chronic inflammation is associated with altered growth and skeletal development, and it is possible that SOCS proteins may have an important role to play in mediating these effects...
  8. ncbi request reprint The effects of recombinant human growth hormone on linear growth in children with Crohn's disease and short stature
    S C Wong
    Bone and Endocrine Research Group, Royal Hospital for Sick Children, Glasgow, UK
    J Pediatr Endocrinol Metab 20:1315-24. 2007
    ..The efficacy of recombinant human growth hormone (rhGH) in treating the growth failure associated with Crohn's disease (CD) is unclear...
  9. doi request reprint Pathophysiology and management of abnormal growth in children with chronic inflammatory bowel disease
    S F Ahmed
    Royal Hospital for Sick Children, University of Glasgow, Glasgow, UK
    World Rev Nutr Diet 106:142-8. 2013
    ..This review will illustrate these aspects by concentrating primarily on the pathophysiology of growth retardation in inflammatory bowel disease and possible interventions for improving growth...
  10. ncbi request reprint Changes in quantitative ultrasound in infants born at less than 32 weeks' gestation over the first 2 years of life: influence of clinical and biochemical changes
    H McDevitt
    Bone and Endocrine Research Group, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK
    Calcif Tissue Int 81:263-9. 2007
    ..Catch-up in SOS occurs postterm in most infants by 6 months and is independent of postnatal growth. Infants with the lowest SOS at term have the fastest rate of catch-up. The opportunity for catch-up may be greatest in early infancy...
  11. doi request reprint Impact of inflammatory bowel disease on pubertal growth
    A Mason
    Developmental Endocrinology Research Group, University of Glasgow, Royal Hospital for Sick Children, Glasgow, UK
    Horm Res Paediatr 76:293-9. 2011
    ..Puberty is thought to be commonly affected in adolescents with inflammatory bowel disease (IBD). Aims: To determine the impact of Crohn's disease (CD) and ulcerative colitis (UC) on the pubertal growth spurt...
  12. doi request reprint Improvement in growth of children with Crohn disease following anti-TNF-α therapy can be independent of pubertal progress and glucocorticoid reduction
    S Malik
    Bone and Endocrine Research Group, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK
    J Pediatr Gastroenterol Nutr 52:31-7. 2011
    ..This is a retrospective study of growth, puberty, and disease activity during the 6 months before starting infliximab (T - 6), at baseline (T0), and for the following 6 months (T + 6) and 12 months (T + 12) in children with CD...
  13. doi request reprint The growth hormone insulin-like growth factor 1 axis in children and adolescents with inflammatory bowel disease and growth retardation
    S C Wong
    Bone and Endocrine Research Group, Royal Hospital for Sick Children, Glasgow, UK
    Clin Endocrinol (Oxf) 73:220-8. 2010
    ..There is scarce knowledge about the growth hormone (GH) insulin-like growth factor-1 (IGF1) axis in children & adolescents with inflammatory bowel disease (IBD) and growth retardation...
  14. ncbi request reprint Longitudinal changes in bone health as assessed by the speed of sound in very low birth weight preterm infants
    C Tomlinson
    Neonatal Unit, Princess Royal Maternity Hospital, Glasgow, UK
    J Pediatr 148:450-5. 2006
    ..To assess longitudinal changes in speed of sound (SOS) in very low birth weight (VLBW) infants and investigate the relationship with markers of osteopathy of prematurity (OP) and clinical illness...
  15. doi request reprint Effect of testosterone therapy for delayed growth and puberty in boys with inflammatory bowel disease
    A Mason
    Developmental Endocrinology Research Group, University of Glasgow, Royal Hospital for Sick Children, Glasgow, UK
    Horm Res Paediatr 75:8-13. 2011
    ..pubertal delay and growth retardation are common in children with inflammatory bowel disease (IBD). Aims: To assess pubertal status and growth in a group of boys with IBD undergoing testosterone therapy for pubertal induction...
  16. doi request reprint Inflammatory cytokines in juvenile idiopathic arthritis: effects on physical growth and the insulin-like-growth factor axis
    S C Wong
    Bone and Endocrine Research Group, Department of Child Health, Royal Hospital for Sick Children, Yorkhill, Glasgow, United Kingdom
    Growth Horm IGF Res 18:369-78. 2008
    ..To investigate the relationship between markers of inflammation with physical growth and systemic markers of GH secretion in JIA...
  17. ncbi request reprint The role of pro-inflammatory cytokines in inflammatory bowel disease growth retardation
    S C Wong
    Bone and Endocrine Research Group, Royal Hospital for Sick Children, Glasgow, UK
    J Pediatr Gastroenterol Nutr 43:144-55. 2006
    ..Well-controlled clinical studies of the respective effect of nutritional support, immunomodulatory therapy, biological agents and growth and puberty promoting agents on managing faltering growth also require further attention...
  18. doi request reprint Promoting growth in chronic inflammatory disease: lessons from studies of the growth plate
    S F Ahmed
    Bone and Endocrine Research Group, Division of Developmental Medicine, University of Glasgow, Royal Hospital for Sick Children, Glasgow, UK
    Horm Res 72:42-7. 2009
    ....
  19. doi request reprint Skeletal morbidity in children receiving chemotherapy for acute lymphoblastic leukaemia
    M Elmantaser
    Department of Child Health, Royal Hospital for Sick Children, University of Glasgow, Glasgow, UK
    Arch Dis Child 95:805-9. 2010
    ..Children receiving chemotherapy for acute lymphoblastic leukaemia (ALL) may be susceptible to skeletal morbidity...
  20. ncbi request reprint Randomized, crossover comparison study of the short-term effect of oral testosterone undecanoate and intramuscular testosterone depot on linear growth and serum bone alkaline phosphatase
    S F Ahmed
    Department of Child Health, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK
    J Pediatr Endocrinol Metab 17:941-50. 2004
    ..To compare the effects of oral testosterone undecanoate (TU) 40 mg daily and intramuscular depot sustanon 50 (SUS), 4 weekly, on short-term growth and bone turnover...
  21. ncbi request reprint Short-term effects of prednisolone and dexamethasone on circulating concentrations of leptin and sex hormone-binding globulin in children being treated for acute lymphoblastic leukaemia
    A M Wallace
    Department of Clinical Biochemistry, Royal Infirmary, Glasgow, UK
    Clin Endocrinol (Oxf) 58:770-6. 2003
    ..This randomization process provided a suitable opportunity to compare the effects of these two administered steroid on surrogate markers of adipocyte activity (leptin) and hyperinsulinaemia/insulin resistance (SHBG)...
  22. doi request reprint The effects of anti-TNF-α treatment with adalimumab on growth in children with Crohn's disease (CD)
    S Malik
    Bone and Endocrine Research Group Royal Hospital for Sick Children, Yorkhill, Glasgow, UK
    J Crohns Colitis 6:337-44. 2012
    ..Adalimumab is used to treat children with Crohn's disease (CD), but the effects of adalimumab on growth in CD have not been studied...
  23. ncbi request reprint Undetectable salivary testosterone in young women with premature ovarian failure
    A Mason
    Bone and Endocrine Research Group, Royal Hospital for Sick Children, Glasgow, UK
    Clin Endocrinol (Oxf) 64:711-4. 2006
    ..The extent of androgen deficiency in young women with premature ovarian failure (POF) is unclear...
  24. doi request reprint Auditing bone densitometry and fractures in children with chronic disease
    S C Wong
    Dept of Child Health, Bone and Endocrine Research Group, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK
    Arch Dis Child 93:705-7. 2008
    ..However, the predictive ability of different bone mineral densities (BM) and BMC cut-offs to identify fracture risk in children with chronic disease needs to be tested for specific disease conditions in larger prospective studies...
  25. ncbi request reprint Cytokine profiling and in vitro studies of murine bone growth using biological fluids from children with juvenile idiopathic arthritis
    V E MacRae
    Department of Child Health, Royal Hospital for Sick Children, Glasgow, UK
    Clin Endocrinol (Oxf) 67:442-8. 2007
    ..Growth retardation in children with chronic inflammatory disease may be partly due to direct effects of pro-inflammatory cytokines on the growth plate and requires further investigation...
  26. ncbi request reprint Glucocorticoid effects on chondrogenesis, differentiation and apoptosis in the murine ATDC5 chondrocyte cell line
    T Mushtaq
    Department of Child Health, Royal Hospital for Sick Children, Yorkhill, Glasgow G3 8SJ, UK
    J Endocrinol 175:705-13. 2002
    ..In conclusion, GC have maximal effects during chondrogenesis; Dex is more potent than Pred and cells exposed to Dex recover but this may be restricted due to differential effects of GC on specific chondrocyte phenotypes...
  27. ncbi request reprint Growth and body composition in children with chronic kidney disease
    R Rashid
    Bone and Endocrine Research Group, Royal Hospital for Sick Children, Yorkhill, Glasgow, G3 8SJ, UK
    Br J Nutr 97:232-8. 2007
    ..In addition, we shall examine the role of body composition in chronic kidney disease, their relationship with growth and nutrition and the potential effect of abnormalities in fat mass and lean mass on long-term morbidity and mortality...
  28. doi request reprint Factors that influence the decision to perform a karyotype in suspected disorders of sex development: lessons from the Scottish genital anomaly network register
    M Rodie
    Department of Child Health, Royal Hospital for Sick Children, Glasgow, UK
    Sex Dev 5:103-8. 2011
    ..Whilst this decision may be related to the complexity of the genital anomaly, there are other factors that may influence this decision, and these require further exploration through more rigorous systems for data collection...
  29. ncbi request reprint The role of sex steroids in controlling pubertal growth
    R J Perry
    Bone and Endocrine Research Group, Royal Hospital for Sick Children, Glasgow, UK
    Clin Endocrinol (Oxf) 68:4-15. 2008
    ..This paper reviews the mechanisms that influence pubertal growth and the problems that are associated with disorders of gonadal function...
  30. ncbi request reprint Quantitative ultrasound assessment of bone health in the neonate
    H McDevitt
    Bone and Endocrine Research Group, Royal Hospital for Sick Children, Glasgow, UK
    Neonatology 91:2-11. 2007
    ..This review will concentrate on the methodology of QUS and the studies that have already been performed in neonates...
  31. doi request reprint A 5-year-old boy with cryptorchidism and pubic hair: investigation and management of apparent male disorders of sex development in mid-childhood
    L S Keir
    Scottish Genital Anomaly Network, Yorkhill, Glasgow, UK
    Horm Res 71:87-92. 2009
    ..Late presentation of congenital adrenal hyperplasia as a 46,XX disorder of sex development due to 11-beta hydroxylase deficiency is uncommon. Such a case raises issues regarding appropriate investigation and management...
  32. ncbi request reprint Short-term growth and bone turnover in children undergoing occlusive steroid ('Wet-Wrap') dressings for treatment of atopic eczema
    R McGowan
    Department of Child Health, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK
    J Dermatolog Treat 14:149-52. 2003
    ..1) respectively (not significant). Non-invasive assessment of the effects of steroid wet-wrap therapy can be performed in children with eczema. These preliminary results show no substantial growth promoting or adverse effects of therapy...
  33. pmc Testosterone measurements in early infancy
    C Tomlinson
    Department of Child Health, Royal Hospital for Sick Children, Glasgow, Scotland, UK
    Arch Dis Child Fetal Neonatal Ed 89:F558-9. 2004
    ..Expected values for male and female infants < 10 days old were 2.5-11.1 (n = 36) and 1.7-5.6 (n = 36) nmol/l respectively. For older neonates (10-50 days) the ranges were 0.2-17.2 (n = 42) and 0.1-1.5 (n = 7) nmol/l respectively...
  34. doi request reprint Growth and skeletal development in families with NOGGIN gene mutations
    C D Oxley
    Department of Paediatric Endocrinology, Royal Hospital for Sick Children, Edinburgh, UK
    Horm Res 69:221-6. 2008
    ..There is a scarcity of data on height as well as bone densitometry in humans with NOGGIN mutations...
  35. ncbi request reprint The psychological impact of genital anomalies on the parents of affected children
    A Duguid
    Royal Hospital for Sick Children, Yorkhill, Glasgow, UK
    Acta Paediatr 96:348-52. 2007
    ..8 years) were recruited through the Scottish Genital Anomaly Network and had a quantitative assessment of parenting stress and coping patterns; a qualitative assessment by a semi-structured interview was also performed in19 parents...
  36. pmc Intersex and gender assignment; the third way?
    S F Ahmed
    Scottish Genital Anomaly Network, Scotland, UK
    Arch Dis Child 89:847-50. 2004
    ..It is no wonder that the birth of a child with complex genital anomalies where the sex of rearing is uncertain at birth, presents difficult clinical and ethical issues...
  37. pmc Quantitative ultrasound assessment of bone in preterm and term neonates
    H McDevitt
    Neonatal Unit, Southern General Hospital, Glasgow, Scotland, UK
    Arch Dis Child Fetal Neonatal Ed 90:F341-2. 2005
    ..The speed of sound in newborn infants is primarily dependent on gestation rather than birth weight...
  38. doi request reprint Exaggerated adrenarche in a cohort of Scottish children: clinical features and biochemistry
    W F Paterson
    Royal Hospital for Sick Children, Glasgow, UK
    Clin Endocrinol (Oxf) 72:496-501. 2010
    ..To investigate the reported association between exaggerated adrenarche (EA) and reduced foetal growth and to identify possible risk factors for future morbidity in Scottish children with clinical features of EA...
  39. ncbi request reprint Short-term effects on linear growth and bone turnover in children randomized to receive prednisolone or dexamethasone
    S F Ahmed
    Department of Child Health, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK
    Clin Endocrinol (Oxf) 57:185-91. 2002
    ..To compare the relative potency of prednisolone (Pred) and dexamethasone (Dex) on short-term growth and bone turnover...
  40. doi request reprint Understanding the genetic aetiology in patients with XY DSD
    S F Ahmed
    School of Medicine, University of Glasgow, Royal Hospital for Sick Children, Yorkhill, Glasgow, UK
    Br Med Bull 106:67-89. 2013
    ..In over half of these cases who have a 46,XY karyotype and who are raised as boys, the underlying aetiology remains unclear...
  41. ncbi request reprint A comparison of the effect of two types of vibration exercise on the endocrine and musculoskeletal system
    M Elmantaser
    Bone and Endocrine Research Group, Department of Child Health, Royal Hospital for Sick Children, Glasgow, UK
    J Musculoskelet Neuronal Interact 12:144-54. 2012
    ..Whole body vibration (WBV) is a novel training intervention but a comparison of different methods of WBV has rarely been performed...
  42. ncbi request reprint Prolonged human chorionic gonadotrophin stimulation as a tool for investigating and managing undescended testes
    J Dixon
    Department of Child Health, Royal Hospital for Sick Children, Glasgow, Scotland, UK
    Clin Endocrinol (Oxf) 67:816-21. 2007
    ..To observe the outcome in a group of children with undescended testes (UDT) given prolonged human chorionic gonadotrophin (hCG) stimulation as part of their management...
  43. ncbi request reprint Bone mineral assessment by dual energy X-ray absorptiometry in children with inflammatory bowel disease: evaluation by age or bone area
    S F Ahmed
    Bone and Endocrine Research Group, Royal Hospital for Sick Children, Yorkhill, Glasgow, United Kingdom
    J Pediatr Gastroenterol Nutr 38:276-80. 2004
    ..Traditionally, bone mineral assessment by dual energy x-ray absorptiometry (DXA) involves comparison to age- and gender-matched reference ranges, and these studies in children with IBD show a high prevalence of osteopenia...
  44. pmc Prevalence of hypospadias and other genital anomalies among singleton births, 1988-1997, in Scotland
    S F Ahmed
    Department of Child Health, Royal Hospital for Sick Children, Yorkhill, Glasgow, Scotland, UK
    Arch Dis Child Fetal Neonatal Ed 89:F149-51. 2004
    ..Considerable debate exists on the epidemiology of genital anomalies...
  45. pmc Biliary hypoplasia in Williams syndrome
    K O'Reilly
    Royal Hospital for Sick Children, Glasgow, UK
    Arch Dis Child 91:420-1. 2006
    ..Neonatal hepatitis and biliary hypoplasia are not recognised features of Williams syndrome. A case of Williams syndrome, presenting with neonatal conjugated hyperbilirubinaemia leading to an initial misdiagnosis is reported...
  46. pmc The impact of corticosteroids on growth and bone health
    T Mushtaq
    Dept of Integrative Biology, Roslin Institute, Edinburgh, UK
    Arch Dis Child 87:93-6. 2002
  47. ncbi request reprint Transdermal testosterone application: pharmacokinetics and effects on pubertal status, short-term growth, and bone turnover
    A Mayo
    Department of Paediatrics, Royal Aberdeen Children s Hospital, Aberdeen AB25 2ZG, Scotland, United Kingdom
    J Clin Endocrinol Metab 89:681-7. 2004
    ..Overnight transdermal testosterone application, as Virormone (5 mg), may be a potentially acceptable method of induction of puberty and stimulates short-term growth and bone turnover...
  48. ncbi request reprint The growth plate sparing effects of the selective glucocorticoid receptor modulator, AL-438
    H C Owen
    Bone Biology Group, Roslin Institute, Edinburgh, UK
    Mol Cell Endocrinol 264:164-70. 2007
    ..This could prove important in the search for new anti-inflammatory treatments for children...
  49. ncbi request reprint Insulin-like growth factor-I augments chondrocyte hypertrophy and reverses glucocorticoid-mediated growth retardation in fetal mice metatarsal cultures
    T Mushtaq
    Bone Biology Group, Roslin Institute, Edinburgh EH25 9PS, United Kingdom
    Endocrinology 145:2478-86. 2004
    ..However, the IGF-I-mediated improvement in growth was at the expense of altering the balance between proliferating and hypertrophic chondrocytes within the metatarsal...
  50. ncbi request reprint Ceramide inhibition of chondrocyte proliferation and bone growth is IGF-I independent
    V E MacRae
    Bone Biology Group, Division of Gene Function and Development, Roslin Institute, Roslin, Midlothian EH25 9PS, UK
    J Endocrinol 191:369-77. 2006
    ..In conclusion, C2-ceramide inhibits proliferation and induces apoptosis in growth plate chondrocytes through an IGF-I independent mechanism...
  51. ncbi request reprint Cytokine actions in growth disorders associated with pediatric chronic inflammatory diseases (review)
    V E MacRae
    Bone Biology Group, Division of Gene Function and Development, Roslin Institute, Roslin, Midlothian EH25 9PS, UK
    Int J Mol Med 18:1011-8. 2006
    ..In this article, we review how cytokines influence child growth by exerting a local effect at the level of the growth plate, and through systemic effects throughout the whole body...
  52. ncbi request reprint The restricted potential for recovery of growth plate chondrogenesis and longitudinal bone growth following exposure to pro-inflammatory cytokines
    V E MacRae
    Bone Biology Group, Division of Gene Function and Development, Roslin Institute, Edinburgh EH25 9PS, UK
    J Endocrinol 189:319-28. 2006
    ..The extent of recovery following cytokine exposure depends on the duration of exposure, and may be incomplete following longer periods of exposure...
  53. pmc Consensus statement on management of intersex disorders
    I A Hughes
    Department of Paediatrics, University of Cambridge, Addenbrooke s Hospital, Box 116, Level 8, Hills Road, Cambridge CB2 2QQ, UK
    Arch Dis Child 91:554-63. 2006
  54. ncbi request reprint Phenotypic features, androgen receptor binding, and mutational analysis in 278 clinical cases reported as androgen insensitivity syndrome
    S F Ahmed
    Department of Paediatrics, University of Cambridge Clinical School, United Kingdom
    J Clin Endocrinol Metab 85:658-65. 2000
    ..The phenotypic heterogeneity among clinically diagnosed cases of AIS emphasizes the need for appropriate comprehensive evaluation of male under-masculinization...
  55. ncbi request reprint Erroneous testosterone assay causing diagnostic confusion in a newborn infant with intersex anomalies
    C Tomlinson
    Acta Paediatr 93:1004-5. 2004
  56. ncbi request reprint The pathophysiology of the growth plate in juvenile idiopathic arthritis
    V E MacRae
    Bone Biology Group, Roslin Institute, Edinburgh, UK
    Rheumatology (Oxford) 45:11-9. 2006
    ..In this article we review these aspects and also discuss the evidence for interaction between the inflammatory cytokine and growth-signalling pathways...
  57. ncbi request reprint PTEN mutation spectrum and genotype-phenotype correlations in Bannayan-Riley-Ruvalcaba syndrome suggest a single entity with Cowden syndrome
    D J Marsh
    Clinical Cancer Genetics and Human Cancer Genetics Programs, Ohio State University Comprehensive Cancer Center, 690C Medical Research Facility, 420 West 12th Avenue, Columbus, OH 43210, USA
    Hum Mol Genet 8:1461-72. 1999
    ..Thus, PTEN mutation-positive CS and BRR may be different presentations of a single syndrome and, hence, both should receive equal attention with respect to cancer surveillance...
  58. doi request reprint Dexamethasone-induced expression of the glucocorticoid response gene lipocalin 2 in chondrocytes
    H C Owen
    Bone Biology Group, Roslin Institute, Edinburgh, UK
    Am J Physiol Endocrinol Metab 294:E1023-34. 2008
    ..05). These results suggest that lipocalin 2 may mediate Dex effects on chondrocytes and provides a potential novel mechanism for GC-induced growth retardation...