Research Topics
| Mark AgiusSummaryAffiliation: University of Cambridge Country: UK Publications
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Detail Information
Publications
The ethics of identifying and treating psychosis earlyMark Agius
Psychiatr Danub 20:93-6. 2008
The use of card sort exercises in the prevention of relapse in serious mental illnessMark Agius
Bedfordshire Centre for Mental Health Research in Association With University of Cambridge, England
Psychiatr Danub 18:61-73. 2006..We look forward to further studies on large groups of patients...
An audit to compare discharge rates and suicidality between antidepressant monotherapies prescribed for unipolar depressionMark Agius
South Essex Partnership University Foundation Trust, UK
Psychiatr Danub 22:350-3. 2010....
Bipolar II Disorder and Borderline Personality Disorder - co-morbidity or spectrum?Mark Agius
South Essex Partnership University Foundation Trust, Bedford, UK
Psychiatr Danub 24:S197-201. 2012..On this basis, it may be reasonable to include Borderline Personality Disorder within a broadly described bipolar spectrum. New details of the common Neurobiological mechanisms continue to emerge...
Clare College - the view of one medical doctorMark Agius
South Essex Partnership University Foundation Trust, Bedford, UK
Psychiatr Danub 24:S7-8. 2012..This short Paper presents Clare College Cambridge, its history and its Medical and other Traditions to the participants in this symposium...
Rationale for clinical interventions in prodromal psychosis. Are such interventions safe?Mark Agius
South Essex Partnership University Foundation Trust, Bedford Hospital, Bedford, UK
Psychiatr Danub 24:S28-35. 2012..Treatment of prodromal psychosis continues to present a number of risks; therefore the decision to treat ultimately must depend on the symptoms presented by the individual...
Do atypical antipsychotics promote neurogenesis as a class effect?Mark Agius
South Essex Partnership University Foundation Trust, Bedford, UK
Psychiatr Danub 24:S191-3. 2012..Hence the question arises as to whether neurogenesis is a class effect which relates to them all. We here present a literature search which we have carried out to establish this...
The issue of five year outcomes in early intervention in psychosis--consequences for the design of servicesMark Agius
Department of Psychiatry University of Cambridge, Clare College Cambridge, South Essex Partnership University Foundation Trust, UK
Psychiatr Danub 24:S316-20. 2012..The reasons for this are described. The Implications for services are that, if outcomes are to be optimised in the treatment of schizophrenia, then assertive treatment in the community needs to be given for as long as possible...
What do large scale studies of medication in schizophrenia add to our management strategies?Mark Agius
South Essex Partnership University Foundation Trust, UK
Psychiatr Danub 22:323-8. 2010..We aimed to conduct a review of the current literature to establish the appropriateness of several recent major clinical studies being used as the basis for clinical guidelines...
An audit to compare discharge rates between antidepressant monotherapies prescribed for pure unipolar depression versus depression in the presence of other indicationsMark Agius
South Essex Partnership University Foundation Trust, UK
Psychiatr Danub 22:346-9. 2010....
Three year outcomes in an early intervention service for psychosis in a multicultural and multiethnic populationMark Agius
Bedfordshire Centre for Mental Health Research in Association with The University of Cambridge, England
Psychiatr Danub 20:494-9. 2008..To test whether there are differences between the three year outcomes of different ethnic groups represented in the patient population of an Early Intervention service for Psychosis...
Early intervention in psychosis. Concepts and service developmentMark Agius
Academic Department of Psychiatry University of Cambridge, Bedfordshire and Luton Partnership Trust, UK
Psychiatr Danub 21:9-20. 2009..The setting up of such a service in Luton, Bedfordshire is then described, and its first results are assessed...
Issues regarding the delivery of early intervention psychiatric services to the South Asian population in EnglandMark Agius
South Essex Partnership University Foundation Trust, Bedfordshire Centre for Mental Health Research in Association with The University of Cambridge, UK
Psychiatr Danub 22:266-9. 2010..The aim of this retrospective study is to gain a better understanding of how well South Asian patients engage with standard psycho-social interventions...
Is oestrogen neuroprotective?Mark Agius
Academic Department of Psychiatry University of Cambridge, Bedfordshire and Luton Partnership Trust, UK
Psychiatr Danub 21:120-7. 2009..However oestrogen has never been used in 'at ultra high risk mental states', perhaps because of concern regarding side effects...
The child as the presenting symptom, and what happens when things go wrong?Mark Agius
Bedfordshire and Luton Partnership Trust, UK
Psychiatr Danub 21:137-41. 2009....
The epidemiology of psychosis in LutonMark Agius
Department of Psychiatry, University of Cambridge, BLPT, UK
Psychiatr Danub 21:508-13. 2009..Variation in rates would have implications for the aetiology of psychosis. The aim was to determine the variation in psychosis prevalence in different areas of a city...
Developing outcome measures for serious mental illness; using early intervention as an exampleMark Agius
Bedfordshire Centre for Mental Health Research in Association with The University of Cambridge, Department of Psychiatry, University of Cambridge, UK
Psychiatr Danub 21:36-42. 2009..We also argue for the use of appropriate rating scales, which measure both the number and the intensity of symptoms and for computer base notes in order to facilitate regular audit...
Does shared care help in the treatment of depression?Mark Agius
South Essex Partnership University Foundation NHS Trust, UK
Psychiatr Danub 22:S18-22. 2010....
Under-diagnosis of bipolar affective disorder in A bedford CMHTMark Agius
South Essex Partnership University Foundation NHS Trust, UK
Psychiatr Danub 22:S36-7. 2010..bipolar disorder is frequently misdiagnosed or diagnosed late. Misdiagnosis of Bipolar Disorder can have serious implications for prognosis and treatment of this condition...
How frequently are atypical antipsychotics used to treat OCD in a British community mental health team?Mark Agius
South Essex Partnership University Foundation NHS Trust, UK
Psychiatr Danub 23:S187-93. 2011..Hence we have attempted to assess the types of treatment received by patients under our care, and the difficulties associated with the treatment of this illness...
Differences between training GPs to manage depression in primary care and issuing them with guidelines, and a system of collaborative care in the treatment of depression between primary and secondary careMark Agius
South Essex Partnership University Foundation NHS Trust, UK
Psychiatr Danub 23:S79-82. 2011..From these we deduce the reasons why collaborative care may offer better treatment outcomes than the issuing of guidelines to GPs...
Depression management - from neurobiology to a shared care approachMark Agius
South Essex Partnership University Foundation NHS Trust, UK
Psychiatr Danub 23:S73-8. 2011..In order for these to be effective as possible, correct diagnosis, consideration of the underlying neurobiology and an appropriate provision of healthcare services must be ensured...
Does early intervention for psychosis work? An analysis of outcomes of early intervention in psychosis based on the critical period hypothesis, measured by number of admissions and bed days used over a period of six years, the first three in an early inteMark Agius
South Essex Partnership University Foundation NHS Trust, UK
Psychiatr Danub 22:S72-84. 2010..The intention was to provide thebest possible care or patients with a first episode of psychosis. Recently however, long term studies over five years have suggested that early gains may be lost...
An early intervention for psychosis service as compared with treatment as usual for first psychotic episodes in a standard community mental health team. Basic concepts and the serviceMark Agius
Bedfordshire Centre For Mental Health Research in Association with the University of Cambridge Weller Wing Bedford Hospital, Bedford, England
Psychiatr Danub 19:5-9. 2007..The development of an early intervention service in Luton, Bedfordshire is then described. Subsequent articles will describe the three year outcomes of this service, compared with treatment as usual in a community mental health team...
Three year outcomes of an early intervention for psychosis service as compared with treatment as usual for first psychotic episodes in a standard community mental health team. Preliminary resultsMark Agius
Bedfordshire Centre For Mental Health Research in Association with the University of Cambridge Weller Wing Bedford Hospital, Bedford, England
Psychiatr Danub 19:10-9. 2007..These results suggest that an ad-hoc early intervention team is more effective than standard community mental health team in treating psychotic illness...
Was Cipriani right? Audits to compare discharge rates and suicidality between antidepressant monotherapies used in a British community mental health teamMark Agius
South Essex Partnership University Foundation NHS Trust, UK
Psychiatr Danub 22:S46-8. 2010..We wished to see whether these findings were reflected in the outcomes of depression treatment in our Community Mental Health Team (CMHT)...
Three year outcomes of an early intervention for psychosis service as compared with treatment as usual for first psychotic episodes in a standard community mental health team - final resultsMark Agius
Bedfordshire Centre for Mental Health Research in Association With University of Cambridge, Weller Wing Bedford Hospital, Bedford, England
Psychiatr Danub 19:130-8. 2007..These results suggest that an ad-hoc Early Intervention Team is more effective than standard Community Mental Health Team in treating psychotic illness...
Guidelines in psychiatryMark Agius
South Essex Partnership University Foundation NHS Trust, UK
Psychiatr Danub 22:S42-5. 2010..guidelines are important to the effective implementation of modern psychiatry...
Outcome measures in psychiatryMark Agius
South Essex Partnership University Foundation NHS Trust, UK
Psychiatr Danub 22:S38-41. 2010..there is a need for outcome measurement in Psychiatry...
The staging model in schizophrenia, and its clinical implicationsMark Agius
South Essex Partnership University Foundation Trust, UK
Psychiatr Danub 22:211-20. 2010..We aim to describe the staging model of schizophrenia, show the neuroimaging and clinical evidence for it, and discuss its implications for treatment...
A comparison of outcomes of patients with depression, recurrent depression, and depression and anxiety within patients in a British CMHTSophie Butler
School of Clinical Medicine, University of Cambridge, UK
Psychiatr Danub 22:387-8. 2010..2...
Depression Treatment by Bedford East Community Mental Health Team an Audit to assess how many patients in a Bedfordshire Community Mental Health Team might safely be transferred to Primary CareSophie Butler
School of Clinical Medicine, University of Cambridge, UK
Psychiatr Danub 22:317-22. 2010..This project is to show what depression treatments are used by Bedford East Community Mental Health Team (BECMHT) and therefore identify whether some of these patients could be appropriately managed in Primary care...
The development of community treatment in Slovenia - first outcomesMark Agius
Bedfordshire Centre for Mental Health Research in Assocication with the University of Cambridge, Deparment of Psychiatry University of Cambridge, Bedfordshire and Luton Partnership Trust, UK
Psychiatr Danub 21:78-80. 2009..The admission and relapse rate of these patients was markedly reduced by working assertively with them in the community...
Suicide risk and choice of antidepressantAbigail Davis
School of Clinical Medicine, University of Cambridge, UK
Psychiatr Danub 22:358-9. 2010....
An audit to compare the efficacy of treatment (as indicated by discharge rates and reduction in suicidality) among patients with refractory depression in a Bedfordshire Community Mental Health Team receiving augmentation therapy with either mirtazepine orSophie Butler
South Essex Partnership University Foundation NHS Trust, UK
Psychiatr Danub 23:S171-4. 2011..Overall we found that augmentation with mirtazepine resulted in better outcomes in terms of both discharge rates and in terms of reduction in suicidality than augmentation with atypical antipsychotics...
Basic standards for management of patients with serious mental illness in the communityMark Agius
Bedfordshire Centre for Mental Health Research, University of Cambridge, England
Psychiatr Danub 17:42-57. 2005
Basic standards for management of patients with common mental illnesses in primary careMark Agius
Bedfordshire Centre for Mental Health Research in Association With University of Cambridge, England
Psychiatr Danub 17:205-20. 2005..We propose a set of standards which are evidence based and which are correlated with the recent WHO declaration on Mental Health in Europe...
Co-morbidity of bipolar affective disorder and obsessive compulsive disorder in a Bedford community psychiatry teamLaura Darby
Department of Psychiatry, University of Cambridge, UK
Psychiatr Danub 23:S130-3. 2011....
Case report of a patient with bipolar disorder - migraines and epilepsyCatherine Zhang
Clinical School, University of Cambridge, Cambridge, UK
Psychiatr Danub 24:S109-11. 2012..Further insight into their link and interactions would facilitate diagnoses of these conditions, as well as improve treatment strategies when they are presented co-morbidly...
Psychosis risk syndrome: is it worth the risk?Chang Ho Yoon
University of Cambridge, School of Clinical Medicine, Cambridge, UK
Psychiatr Danub 24:S36-40. 2012..Here we review the different opinions which have been expressed regarding this issue and consider whether this is the appropriate time to include 'Psychosis Risk Syndrome' as an independently listed psychiatric diagnosis...
Psychological treatments and brain biologyRashid Zaman
Bedfordshire Centre for Mental Health Research in Association with The University of Cambridge, UK
Psychiatr Danub 21:31-5. 2009..This is a summary and transcription of a talk given to ISPS Slovenia in Bled in 2006. It assesses the research evidence for a biological basis for psychological treatments...
The development of a Leonardo Program for teaching community psychiatryMark Agius
Bedfordshire Centre for Mental Health Research in Association With University of Cambridge, England
Psychiatr Danub 18:193-9. 2006..The results of this program are interpreted in terms of theory of Adult Learning. It was found that the Leonardo EU program was useful in teaching Community Mental Health...
The differences between typical and atypical antipsychotics: the effects on neurogenesisKarandeep Singh Nandra
Clare College Cambridge, Cambridge, UK
Psychiatr Danub 24:S95-9. 2012..Atypical drugs can also prevent or reverse the effects of haloperidol induced toxicity. The mechanism involves the inverse agonism of 5HT receptors, particularly those of the 2A subset, but the situation is considerably more complicated...
The dramatic effects of Galantamine in a patient with early-onset Alzheimer's diseaseHarveer Dev
School of Clinical Medicine, University of Cambridge, UK
Psychiatr Danub 22:367-9. 2010..She was diagnosed with non-familial early-onset Alzheimer's Disease (EOAD) and started on 8mg daily of the acetylcholinesterase inhibitor Galantamine...
Secondary enuresis & body dysmorphic disorder in a caucasian male with catatonic schizophrenia: a case reportNuruz Zaman
South Essex Partnership University Foundation NHS Trust, UK
Psychiatr Danub 22:S53-5. 2010..We explore the mechanisms of incontinence in Schizophrenia and those due to Clozapine. This case highlights the need to inquire about incontinence in patients with schizophrenia prior to prescribing clozapine...
"My new Alfa Romeo GT is not in the garage any more": Cognitive behavioural therapy of panic disorder with agoraphobia co morbid with psychosisEma N Gruber
Neuropsychiatry hospital Dr I Barbot, PP 30, 44317 Popovaca, Croatia
Psychiatr Danub 18:205-11. 2006..This case emphasises the therapeutic value for certain patients of focussing therapy on the non-psychotic symptoms once the acute psychotic state has been managed...
"Since I have my case manager, I am back to life" case management in CroatiaEma N Gruber
Neuropsychiatric hospital Dr I Barbot, Popovaca, Croatia
Psychiatr Danub 20:63-70. 2008..A case report of a patient and the work of her case manager as well as the case manager's diary (Gruber 2007) and the Croatian model of case management is presented in this article...
Duration of untreated psychosis and it's effect on the functional outcome in schizophrenia - preliminary resultsBrigita Novak Sarotar
University Psychiatric Hospital Ljubljana, Studenec 48, 1260 Ljubljana, Slovenia
Psychiatr Danub 20:179-83. 2008....
On patient centred psychiatryMark Agius
Psychiatr Danub 20:337-9. 2008
The clinical dilemma--prescribing in pregnancyRoshelle Ramkisson
Bolton, Salford and Trafford Mental Health NHS Trus, England
Psychiatr Danub 20:88-90. 2008..We present two cases where a choice had to be made as to whether to prescribe Olanzapine during pregnancy, with different results...
Early intervention in psychosisAlma Dzubur-Kulenovic
Department of Psychiatry, University of Sarajevol
Med Arh 57:61-3. 2003..The paper will review the development of these guidelines, describe them, and suggest outcome measures for the treatment of first and early episodes...
The role of the primary care mental health workerMark Agius
Br J Gen Pract 57:326. 2007
The patient with schizophrenia and his father. The father's role and personality traits in the dynamics of the family with a son suffering from schizophreniaIvan Urlic
Psychiatric Clinic, Clinical Hospital Split, Split, Croatia
Psychiatr Danub 19:154-72. 2007..Among the conclusions reached, the phenomenon of "dead father" is emphasized as one of the main factors in the onset and development of schizophrenic disorder/disturbance...
Atypical antipsychotic prescribing and diabetesMark Agius
Psychiatr Danub 19:89-90. 2007
Developing primary care treatment of depressionMark Agius
Br J Gen Pract 57:501-2. 2007
Group psychotherapy for parents of patients with schizophreniaEma N Gruber
Neuro psychiatric Hospital Dr I Barbot Popovaéa, Croatia
Int J Soc Psychiatry 52:487-500. 2006..The aim was to investigate whether this approach would enable parents of patients with schizophrenia to re-establish their psychic balance and the balance of the whole family system by reducing high expressed emotion...
