Mark Agius

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi request reprint The ethics of identifying and treating psychosis early
    Mark Agius
    Psychiatr Danub 20:93-6. 2008
  2. ncbi request reprint The use of card sort exercises in the prevention of relapse in serious mental illness
    Mark Agius
    Bedfordshire Centre for Mental Health Research in Association With University of Cambridge, England
    Psychiatr Danub 18:61-73. 2006
  3. ncbi request reprint An audit to compare discharge rates and suicidality between antidepressant monotherapies prescribed for unipolar depression
    Mark Agius
    South Essex Partnership University Foundation Trust, UK
    Psychiatr Danub 22:350-3. 2010
  4. ncbi request reprint Bipolar II Disorder and Borderline Personality Disorder - co-morbidity or spectrum?
    Mark Agius
    South Essex Partnership University Foundation Trust, Bedford, UK
    Psychiatr Danub 24:S197-201. 2012
  5. ncbi request reprint An audit to assess the consequences of the use of a pluripotential risk syndrome: the case to move on from "psychosis risk syndrome (PRS) "
    Mark Agius
    SEPT at Weller Wing, Bedford Hospital, Bedford, Bedfordshire, MK42 9DJ, UK
    Psychiatr Danub 25:S282-5. 2013
  6. ncbi request reprint Clare College - the view of one medical doctor
    Mark Agius
    South Essex Partnership University Foundation Trust, Bedford, UK
    Psychiatr Danub 24:S7-8. 2012
  7. ncbi request reprint Rationale for clinical interventions in prodromal psychosis. Are such interventions safe?
    Mark Agius
    South Essex Partnership University Foundation Trust, Bedford Hospital, Bedford, UK
    Psychiatr Danub 24:S28-35. 2012
  8. ncbi request reprint Do atypical antipsychotics promote neurogenesis as a class effect?
    Mark Agius
    South Essex Partnership University Foundation Trust, Bedford, UK
    Psychiatr Danub 24:S191-3. 2012
  9. ncbi request reprint The issue of five year outcomes in early intervention in psychosis--consequences for the design of services
    Mark Agius
    Department of Psychiatry University of Cambridge, Clare College Cambridge, South Essex Partnership University Foundation Trust, UK
    Psychiatr Danub 24:S316-20. 2012
  10. ncbi request reprint Under-diagnosis of bipolar affective disorder in A bedford CMHT
    Mark Agius
    South Essex Partnership University Foundation NHS Trust, UK
    Psychiatr Danub 22:S36-7. 2010

Collaborators

  • Suzanne P Murphy
  • Koksal Alptekin
  • Charlotte Wilson
  • Vesna Svab
  • Sophia Ulhaq
  • Patrick D McGorry
  • Sanja Martić-Biocina
  • Marga Kocmur
  • Rashid Zaman
  • Sophie Butler
  • Ema N Gruber
  • Rakhee Vaja
  • Jina Pakpoor
  • Singdha M Reddy
  • Shevonne Matheiken
  • Catherine Zhang
  • Karandeep Singh Nandra
  • Chang Ho Yoon
  • Laura Darby
  • Harveer Dev
  • Abigail Davis
  • Nuruz Zaman
  • Roshelle Ramkisson
  • Brigita Novak Sarotar
  • Ivan Urlic
  • Alma Dzubur-Kulenovic
  • Calum T Goudie
  • Sajeeva Jaylath
  • Clare Holt
  • Kamilla Klepacka
  • Milind Karale
  • Michael Gilhooley
  • Peter Pregelj
  • Marjeta Blinc Pesek
  • Margaret Campbell
  • Sladana Ivezić-Strkalj
  • Milka Kajević
  • Sanja Biocina-Martić
  • Veljko Dordevic
  • Peter Jones
  • Olwyn Gallagher

Detail Information

Publications61

  1. ncbi request reprint The ethics of identifying and treating psychosis early
    Mark Agius
    Psychiatr Danub 20:93-6. 2008
  2. ncbi request reprint The use of card sort exercises in the prevention of relapse in serious mental illness
    Mark Agius
    Bedfordshire Centre for Mental Health Research in Association With University of Cambridge, England
    Psychiatr Danub 18:61-73. 2006
    ..We look forward to further studies on large groups of patients...
  3. ncbi request reprint An audit to compare discharge rates and suicidality between antidepressant monotherapies prescribed for unipolar depression
    Mark Agius
    South Essex Partnership University Foundation Trust, UK
    Psychiatr Danub 22:350-3. 2010
    ....
  4. ncbi request reprint Bipolar II Disorder and Borderline Personality Disorder - co-morbidity or spectrum?
    Mark Agius
    South Essex Partnership University Foundation Trust, Bedford, UK
    Psychiatr Danub 24:S197-201. 2012
    ..On this basis, it may be reasonable to include Borderline Personality Disorder within a broadly described bipolar spectrum. New details of the common Neurobiological mechanisms continue to emerge...
  5. ncbi request reprint An audit to assess the consequences of the use of a pluripotential risk syndrome: the case to move on from "psychosis risk syndrome (PRS) "
    Mark Agius
    SEPT at Weller Wing, Bedford Hospital, Bedford, Bedfordshire, MK42 9DJ, UK
    Psychiatr Danub 25:S282-5. 2013
    ..Hence we propose that the concept of a "Pluripotent risk syndrome" is in our view born out...
  6. ncbi request reprint Clare College - the view of one medical doctor
    Mark Agius
    South Essex Partnership University Foundation Trust, Bedford, UK
    Psychiatr Danub 24:S7-8. 2012
    ..This short Paper presents Clare College Cambridge, its history and its Medical and other Traditions to the participants in this symposium...
  7. ncbi request reprint Rationale for clinical interventions in prodromal psychosis. Are such interventions safe?
    Mark Agius
    South Essex Partnership University Foundation Trust, Bedford Hospital, Bedford, UK
    Psychiatr Danub 24:S28-35. 2012
    ..Treatment of prodromal psychosis continues to present a number of risks; therefore the decision to treat ultimately must depend on the symptoms presented by the individual...
  8. ncbi request reprint Do atypical antipsychotics promote neurogenesis as a class effect?
    Mark Agius
    South Essex Partnership University Foundation Trust, Bedford, UK
    Psychiatr Danub 24:S191-3. 2012
    ..Hence the question arises as to whether neurogenesis is a class effect which relates to them all. We here present a literature search which we have carried out to establish this...
  9. ncbi request reprint The issue of five year outcomes in early intervention in psychosis--consequences for the design of services
    Mark Agius
    Department of Psychiatry University of Cambridge, Clare College Cambridge, South Essex Partnership University Foundation Trust, UK
    Psychiatr Danub 24:S316-20. 2012
    ..The reasons for this are described. The Implications for services are that, if outcomes are to be optimised in the treatment of schizophrenia, then assertive treatment in the community needs to be given for as long as possible...
  10. ncbi request reprint Under-diagnosis of bipolar affective disorder in A bedford CMHT
    Mark Agius
    South Essex Partnership University Foundation NHS Trust, UK
    Psychiatr Danub 22:S36-7. 2010
    ..bipolar disorder is frequently misdiagnosed or diagnosed late. Misdiagnosis of Bipolar Disorder can have serious implications for prognosis and treatment of this condition...
  11. ncbi request reprint Early intervention in psychosis. Concepts and service development
    Mark Agius
    Academic Department of Psychiatry University of Cambridge, Bedfordshire and Luton Partnership Trust, UK
    Psychiatr Danub 21:9-20. 2009
    ..The setting up of such a service in Luton, Bedfordshire is then described, and its first results are assessed...
  12. ncbi request reprint Is oestrogen neuroprotective?
    Mark Agius
    Academic Department of Psychiatry University of Cambridge, Bedfordshire and Luton Partnership Trust, UK
    Psychiatr Danub 21:120-7. 2009
    ..However oestrogen has never been used in 'at ultra high risk mental states', perhaps because of concern regarding side effects...
  13. ncbi request reprint The child as the presenting symptom, and what happens when things go wrong?
    Mark Agius
    Bedfordshire and Luton Partnership Trust, UK
    Psychiatr Danub 21:137-41. 2009
    ....
  14. ncbi request reprint The epidemiology of psychosis in Luton
    Mark Agius
    Department of Psychiatry, University of Cambridge, BLPT, UK
    Psychiatr Danub 21:508-13. 2009
    ..Variation in rates would have implications for the aetiology of psychosis. The aim was to determine the variation in psychosis prevalence in different areas of a city...
  15. ncbi request reprint Developing outcome measures for serious mental illness; using early intervention as an example
    Mark Agius
    Bedfordshire Centre for Mental Health Research in Association with The University of Cambridge, Department of Psychiatry, University of Cambridge, UK
    Psychiatr Danub 21:36-42. 2009
    ..We also argue for the use of appropriate rating scales, which measure both the number and the intensity of symptoms and for computer base notes in order to facilitate regular audit...
  16. ncbi request reprint The staging model in schizophrenia, and its clinical implications
    Mark Agius
    South Essex Partnership University Foundation Trust, UK
    Psychiatr Danub 22:211-20. 2010
    ..We aim to describe the staging model of schizophrenia, show the neuroimaging and clinical evidence for it, and discuss its implications for treatment...
  17. ncbi request reprint Issues regarding the delivery of early intervention psychiatric services to the South Asian population in England
    Mark Agius
    South Essex Partnership University Foundation Trust, Bedfordshire Centre for Mental Health Research in Association with The University of Cambridge, UK
    Psychiatr Danub 22:266-9. 2010
    ..The aim of this retrospective study is to gain a better understanding of how well South Asian patients engage with standard psycho-social interventions...
  18. ncbi request reprint Does shared care help in the treatment of depression?
    Mark Agius
    South Essex Partnership University Foundation NHS Trust, UK
    Psychiatr Danub 22:S18-22. 2010
    ....
  19. ncbi request reprint An audit to compare discharge rates between antidepressant monotherapies prescribed for pure unipolar depression versus depression in the presence of other indications
    Mark Agius
    South Essex Partnership University Foundation Trust, UK
    Psychiatr Danub 22:346-9. 2010
    ....
  20. ncbi request reprint Three year outcomes in an early intervention service for psychosis in a multicultural and multiethnic population
    Mark Agius
    Bedfordshire Centre for Mental Health Research in Association with The University of Cambridge, England
    Psychiatr Danub 20:494-9. 2008
    ..To test whether there are differences between the three year outcomes of different ethnic groups represented in the patient population of an Early Intervention service for Psychosis...
  21. ncbi request reprint Outcome measures in psychiatry
    Mark Agius
    South Essex Partnership University Foundation NHS Trust, UK
    Psychiatr Danub 22:S38-41. 2010
    ..there is a need for outcome measurement in Psychiatry...
  22. ncbi request reprint Guidelines in psychiatry
    Mark Agius
    South Essex Partnership University Foundation NHS Trust, UK
    Psychiatr Danub 22:S42-5. 2010
    ..guidelines are important to the effective implementation of modern psychiatry...
  23. ncbi request reprint What do large scale studies of medication in schizophrenia add to our management strategies?
    Mark Agius
    South Essex Partnership University Foundation Trust, UK
    Psychiatr Danub 22:323-8. 2010
    ..We aimed to conduct a review of the current literature to establish the appropriateness of several recent major clinical studies being used as the basis for clinical guidelines...
  24. ncbi request reprint How frequently are atypical antipsychotics used to treat OCD in a British community mental health team?
    Mark Agius
    South Essex Partnership University Foundation NHS Trust, UK
    Psychiatr Danub 23:S187-93. 2011
    ..Hence we have attempted to assess the types of treatment received by patients under our care, and the difficulties associated with the treatment of this illness...
  25. ncbi request reprint An early intervention for psychosis service as compared with treatment as usual for first psychotic episodes in a standard community mental health team. Basic concepts and the service
    Mark Agius
    Bedfordshire Centre For Mental Health Research in Association with the University of Cambridge Weller Wing Bedford Hospital, Bedford, England
    Psychiatr Danub 19:5-9. 2007
    ..The development of an early intervention service in Luton, Bedfordshire is then described. Subsequent articles will describe the three year outcomes of this service, compared with treatment as usual in a community mental health team...
  26. ncbi request reprint Three year outcomes of an early intervention for psychosis service as compared with treatment as usual for first psychotic episodes in a standard community mental health team. Preliminary results
    Mark Agius
    Bedfordshire Centre For Mental Health Research in Association with the University of Cambridge Weller Wing Bedford Hospital, Bedford, England
    Psychiatr Danub 19:10-9. 2007
    ..These results suggest that an ad-hoc early intervention team is more effective than standard community mental health team in treating psychotic illness...
  27. ncbi request reprint Three year outcomes of an early intervention for psychosis service as compared with treatment as usual for first psychotic episodes in a standard community mental health team - final results
    Mark Agius
    Bedfordshire Centre for Mental Health Research in Association With University of Cambridge, Weller Wing Bedford Hospital, Bedford, England
    Psychiatr Danub 19:130-8. 2007
    ..These results suggest that an ad-hoc Early Intervention Team is more effective than standard Community Mental Health Team in treating psychotic illness...
  28. ncbi request reprint Differences between training GPs to manage depression in primary care and issuing them with guidelines, and a system of collaborative care in the treatment of depression between primary and secondary care
    Mark Agius
    South Essex Partnership University Foundation NHS Trust, UK
    Psychiatr Danub 23:S79-82. 2011
    ..From these we deduce the reasons why collaborative care may offer better treatment outcomes than the issuing of guidelines to GPs...
  29. ncbi request reprint Was Cipriani right? Audits to compare discharge rates and suicidality between antidepressant monotherapies used in a British community mental health team
    Mark Agius
    South Essex Partnership University Foundation NHS Trust, UK
    Psychiatr Danub 22:S46-8. 2010
    ..We wished to see whether these findings were reflected in the outcomes of depression treatment in our Community Mental Health Team (CMHT)...
  30. ncbi request reprint Does early intervention for psychosis work? An analysis of outcomes of early intervention in psychosis based on the critical period hypothesis, measured by number of admissions and bed days used over a period of six years, the first three in an early inte
    Mark Agius
    South Essex Partnership University Foundation NHS Trust, UK
    Psychiatr Danub 22:S72-84. 2010
    ..The intention was to provide thebest possible care or patients with a first episode of psychosis. Recently however, long term studies over five years have suggested that early gains may be lost...
  31. ncbi request reprint Depression management - from neurobiology to a shared care approach
    Mark Agius
    South Essex Partnership University Foundation NHS Trust, UK
    Psychiatr Danub 23:S73-8. 2011
    ..In order for these to be effective as possible, correct diagnosis, consideration of the underlying neurobiology and an appropriate provision of healthcare services must be ensured...
  32. ncbi request reprint A comparison of outcomes of patients with depression, recurrent depression, and depression and anxiety within patients in a British CMHT
    Sophie Butler
    School of Clinical Medicine, University of Cambridge, UK
    Psychiatr Danub 22:387-8. 2010
    ..2...
  33. ncbi request reprint Depression Treatment by Bedford East Community Mental Health Team an Audit to assess how many patients in a Bedfordshire Community Mental Health Team might safely be transferred to Primary Care
    Sophie Butler
    School of Clinical Medicine, University of Cambridge, UK
    Psychiatr Danub 22:317-22. 2010
    ..This project is to show what depression treatments are used by Bedford East Community Mental Health Team (BECMHT) and therefore identify whether some of these patients could be appropriately managed in Primary care...
  34. ncbi request reprint The development of community treatment in Slovenia - first outcomes
    Mark Agius
    Bedfordshire Centre for Mental Health Research in Assocication with the University of Cambridge, Deparment of Psychiatry University of Cambridge, Bedfordshire and Luton Partnership Trust, UK
    Psychiatr Danub 21:78-80. 2009
    ..The admission and relapse rate of these patients was markedly reduced by working assertively with them in the community...
  35. ncbi request reprint Suicide risk and choice of antidepressant
    Abigail Davis
    School of Clinical Medicine, University of Cambridge, UK
    Psychiatr Danub 22:358-9. 2010
    ....
  36. ncbi request reprint Basic standards for management of patients with serious mental illness in the community
    Mark Agius
    Bedfordshire Centre for Mental Health Research, University of Cambridge, England
    Psychiatr Danub 17:42-57. 2005
  37. ncbi request reprint An audit to compare the efficacy of treatment (as indicated by discharge rates and reduction in suicidality) among patients with refractory depression in a Bedfordshire Community Mental Health Team receiving augmentation therapy with either mirtazepine or
    Sophie Butler
    South Essex Partnership University Foundation NHS Trust, UK
    Psychiatr Danub 23:S171-4. 2011
    ..Overall we found that augmentation with mirtazepine resulted in better outcomes in terms of both discharge rates and in terms of reduction in suicidality than augmentation with atypical antipsychotics...
  38. ncbi request reprint Basic standards for management of patients with common mental illnesses in primary care
    Mark Agius
    Bedfordshire Centre for Mental Health Research in Association With University of Cambridge, England
    Psychiatr Danub 17:205-20. 2005
    ..We propose a set of standards which are evidence based and which are correlated with the recent WHO declaration on Mental Health in Europe...
  39. ncbi request reprint Co-morbidity of bipolar affective disorder and obsessive compulsive disorder in a Bedford community psychiatry team
    Laura Darby
    Department of Psychiatry, University of Cambridge, UK
    Psychiatr Danub 23:S130-3. 2011
    ....
  40. ncbi request reprint Psychosis risk syndrome: is it worth the risk?
    Chang Ho Yoon
    University of Cambridge, School of Clinical Medicine, Cambridge, UK
    Psychiatr Danub 24:S36-40. 2012
    ..Here we review the different opinions which have been expressed regarding this issue and consider whether this is the appropriate time to include 'Psychosis Risk Syndrome' as an independently listed psychiatric diagnosis...
  41. ncbi request reprint Audit of the prevalence of anxiety in bipolar disorder--a comorbidity that requires attention and action
    Jina Pakpoor
    Selwyn College Cambridge, School of Clinical Medicine, University of Cambridge, Cambridge, UK
    Psychiatr Danub 25:S354-7. 2013
    ..The frequent occurrence of anxiety symptoms and BPD together has informed theories of the shared aetiology of these conditions. ..
  42. ncbi request reprint Audit to assess the prevalence of autoimmune disorders among patients suffering from psychiatric illnesses
    Rakhee Vaja
    Department of Psychiatry University of Cambridge, Cambridge, UK
    Psychiatr Danub 25:S305-14. 2013
    ..This includes screening opportunities and risk assessments, as well as potential for new pharmacological therapies based around immune regulation. ..
  43. ncbi request reprint Case report of a patient with bipolar disorder - migraines and epilepsy
    Catherine Zhang
    Clinical School, University of Cambridge, Cambridge, UK
    Psychiatr Danub 24:S109-11. 2012
    ..Further insight into their link and interactions would facilitate diagnoses of these conditions, as well as improve treatment strategies when they are presented co-morbidly...
  44. ncbi request reprint Psychological treatments and brain biology
    Rashid Zaman
    Bedfordshire Centre for Mental Health Research in Association with The University of Cambridge, UK
    Psychiatr Danub 21:31-5. 2009
    ..This is a summary and transcription of a talk given to ISPS Slovenia in Bled in 2006. It assesses the research evidence for a biological basis for psychological treatments...
  45. ncbi request reprint The development of a Leonardo Program for teaching community psychiatry
    Mark Agius
    Bedfordshire Centre for Mental Health Research in Association With University of Cambridge, England
    Psychiatr Danub 18:193-9. 2006
    ..The results of this program are interpreted in terms of theory of Adult Learning. It was found that the Leonardo EU program was useful in teaching Community Mental Health...
  46. ncbi request reprint The metabolic syndrome in untreated schizophrenia patients: prevalence and putative mechanisms
    Singdha M Reddy
    School of Clinical Medicine, Department of Psychiatry, The University of Cambridge, UK
    Psychiatr Danub 25:S94-8. 2013
    ..The huge cardiovascular burden makes it crucial to establish the causes and optimal management of MetS in schizophrenia. ..
  47. ncbi request reprint The development of an assessment clinic (ASPA) in South Essex Partnership Trust. Observations and outcomes in the period December 2011-April 2013
    Shevonne Matheiken
    South Essex Partnership University Foundation Trust, UK
    Psychiatr Danub 25:S350-3. 2013
    ..Within the period, approximately one third of patients were referred back to primary care, one third were still in the assessment process, and one third had been admitted to secondary care community services. ..
  48. ncbi request reprint The differences between typical and atypical antipsychotics: the effects on neurogenesis
    Karandeep Singh Nandra
    Clare College Cambridge, Cambridge, UK
    Psychiatr Danub 24:S95-9. 2012
    ..Atypical drugs can also prevent or reverse the effects of haloperidol induced toxicity. The mechanism involves the inverse agonism of 5HT receptors, particularly those of the 2A subset, but the situation is considerably more complicated...
  49. ncbi request reprint The dramatic effects of Galantamine in a patient with early-onset Alzheimer's disease
    Harveer Dev
    School of Clinical Medicine, University of Cambridge, UK
    Psychiatr Danub 22:367-9. 2010
    ..She was diagnosed with non-familial early-onset Alzheimer's Disease (EOAD) and started on 8mg daily of the acetylcholinesterase inhibitor Galantamine...
  50. ncbi request reprint Secondary enuresis & body dysmorphic disorder in a caucasian male with catatonic schizophrenia: a case report
    Nuruz Zaman
    South Essex Partnership University Foundation NHS Trust, UK
    Psychiatr Danub 22:S53-5. 2010
    ..We explore the mechanisms of incontinence in Schizophrenia and those due to Clozapine. This case highlights the need to inquire about incontinence in patients with schizophrenia prior to prescribing clozapine...
  51. ncbi request reprint "My new Alfa Romeo GT is not in the garage any more": Cognitive behavioural therapy of panic disorder with agoraphobia co morbid with psychosis
    Ema N Gruber
    Neuropsychiatry hospital Dr I Barbot, PP 30, 44317 Popovaca, Croatia
    Psychiatr Danub 18:205-11. 2006
    ..This case emphasises the therapeutic value for certain patients of focussing therapy on the non-psychotic symptoms once the acute psychotic state has been managed...
  52. ncbi request reprint Duration of untreated psychosis and it's effect on the functional outcome in schizophrenia - preliminary results
    Brigita Novak Sarotar
    University Psychiatric Hospital Ljubljana, Studenec 48, 1260 Ljubljana, Slovenia
    Psychiatr Danub 20:179-83. 2008
    ....
  53. ncbi request reprint "Since I have my case manager, I am back to life" case management in Croatia
    Ema N Gruber
    Neuropsychiatric hospital Dr I Barbot, Popovaca, Croatia
    Psychiatr Danub 20:63-70. 2008
    ..A case report of a patient and the work of her case manager as well as the case manager's diary (Gruber 2007) and the Croatian model of case management is presented in this article...
  54. pmc Developing primary care treatment of depression
    Mark Agius
    Br J Gen Pract 57:501-2. 2007
  55. ncbi request reprint On patient centred psychiatry
    Mark Agius
    Psychiatr Danub 20:337-9. 2008
  56. ncbi request reprint The clinical dilemma--prescribing in pregnancy
    Roshelle Ramkisson
    Bolton, Salford and Trafford Mental Health NHS Trus, England
    Psychiatr Danub 20:88-90. 2008
    ..We present two cases where a choice had to be made as to whether to prescribe Olanzapine during pregnancy, with different results...
  57. pmc The role of the primary care mental health worker
    Mark Agius
    Br J Gen Pract 57:326. 2007
  58. ncbi request reprint Early intervention in psychosis
    Alma Dzubur-Kulenovic
    Department of Psychiatry, University of Sarajevol
    Med Arh 57:61-3. 2003
    ..The paper will review the development of these guidelines, describe them, and suggest outcome measures for the treatment of first and early episodes...
  59. ncbi request reprint The patient with schizophrenia and his father. The father's role and personality traits in the dynamics of the family with a son suffering from schizophrenia
    Ivan Urlic
    Psychiatric Clinic, Clinical Hospital Split, Split, Croatia
    Psychiatr Danub 19:154-72. 2007
    ..Among the conclusions reached, the phenomenon of "dead father" is emphasized as one of the main factors in the onset and development of schizophrenic disorder/disturbance...
  60. ncbi request reprint Atypical antipsychotic prescribing and diabetes
    Mark Agius
    Psychiatr Danub 19:89-90. 2007
  61. ncbi request reprint Group psychotherapy for parents of patients with schizophrenia
    Ema N Gruber
    Neuro psychiatric Hospital Dr I Barbot Popovaéa, Croatia
    Int J Soc Psychiatry 52:487-500. 2006
    ..The aim was to investigate whether this approach would enable parents of patients with schizophrenia to re-establish their psychic balance and the balance of the whole family system by reducing high expressed emotion...