Amanda I Adler

Summary

Affiliation: University of Oxford
Country: UK

Publications

  1. ncbi request reprint Managing diabetes: what to do about cardiovascular disease
    Amanda I Adler
    Diabetes Trials Unit, Oxford Centre for Diabetes and Metabolism, Churchill Site, Old Road, Headington, Oxford OX3, UK
    Diabetes Res Clin Pract 61:S3-8. 2003
  2. ncbi request reprint Development and progression of nephropathy in type 2 diabetes: the United Kingdom Prospective Diabetes Study (UKPDS 64)
    Amanda I Adler
    Diabetes Trials Unit, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, and South Cleveland Hospital, Cleveland, United Kingdom
    Kidney Int 63:225-32. 2003
  3. ncbi request reprint Obesity and target organ damage: diabetes
    A Adler
    Radcliffe Infirmary University of Oxford, Oxford, UK
    Int J Obes Relat Metab Disord 26:S11-4. 2002
  4. ncbi request reprint Insulin sensitivity at diagnosis of Type 2 diabetes is not associated with subsequent cardiovascular disease (UKPDS 67)
    A I Adler
    Diabetes Trials Unit, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK
    Diabet Med 22:306-11. 2005
  5. ncbi request reprint UKPDS 59: hyperglycemia and other potentially modifiable risk factors for peripheral vascular disease in type 2 diabetes
    Amanda I Adler
    Diabetes Trials Unit, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK
    Diabetes Care 25:894-9. 2002
  6. ncbi request reprint Cardiovascular risk reduction in diabetes: underemphasised and overdue. Messages from major trials
    A I Adler
    Diabetes Trials Unit, Oxford University, Radcliffe Infirmary
    Clin Med 1:472-7. 2001
  7. ncbi request reprint Treating high blood pressure in diabetes: the evidence
    Amanda I Adler
    Diabetes Trials Unit, Oxford University, Oxford, England
    Semin Vasc Med 2:127-37. 2002
  8. ncbi request reprint Risk factors for diabetic neuropathy and foot ulceration
    A Adler
    Diabetes Trials Unit, Nuffield Department of Clinical Medicine, Oxford University, Radcliffe Infirmary, Block II, Woodstock Road, Oxford OX2 6HE, UK
    Curr Diab Rep 1:202-7. 2001
  9. ncbi request reprint Risk factors for renal dysfunction in type 2 diabetes: U.K. Prospective Diabetes Study 74
    Ravi Retnakaran
    Diabetes Trial Unit, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK
    Diabetes 55:1832-9. 2006
  10. ncbi request reprint Cost-effectiveness analysis of intensive blood-glucose control with metformin in overweight patients with type II diabetes (UKPDS No. 51)
    P Clarke
    Health Economics Research Centre, Department of Public Health, University of Oxford, Institute of Health Sciences, Headington, Oxford OX3 7LF, UK
    Diabetologia 44:298-304. 2001

Detail Information

Publications21

  1. ncbi request reprint Managing diabetes: what to do about cardiovascular disease
    Amanda I Adler
    Diabetes Trials Unit, Oxford Centre for Diabetes and Metabolism, Churchill Site, Old Road, Headington, Oxford OX3, UK
    Diabetes Res Clin Pract 61:S3-8. 2003
    ..Other interventions include aspirin therapy and the use of angiotensin-converting enzyme (ACE) inhibitors...
  2. ncbi request reprint Development and progression of nephropathy in type 2 diabetes: the United Kingdom Prospective Diabetes Study (UKPDS 64)
    Amanda I Adler
    Diabetes Trials Unit, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, and South Cleveland Hospital, Cleveland, United Kingdom
    Kidney Int 63:225-32. 2003
    ..This study sought to describe the development and progression through the stages of microalbuminuria, macroalbuminuria, persistently elevated plasma creatinine or renal replacement therapy (RRT), and death...
  3. ncbi request reprint Obesity and target organ damage: diabetes
    A Adler
    Radcliffe Infirmary University of Oxford, Oxford, UK
    Int J Obes Relat Metab Disord 26:S11-4. 2002
    ..However, many questions remain to be answered...
  4. ncbi request reprint Insulin sensitivity at diagnosis of Type 2 diabetes is not associated with subsequent cardiovascular disease (UKPDS 67)
    A I Adler
    Diabetes Trials Unit, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Churchill Hospital, Oxford, UK
    Diabet Med 22:306-11. 2005
    ..Whether insulin sensitivity measured after diagnosis of diabetes is associated with incident cardiovascular disease was evaluated in this prospective study...
  5. ncbi request reprint UKPDS 59: hyperglycemia and other potentially modifiable risk factors for peripheral vascular disease in type 2 diabetes
    Amanda I Adler
    Diabetes Trials Unit, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK
    Diabetes Care 25:894-9. 2002
    ..To determine the role of hyperglycemia in prospective analyses of peripheral vascular disease (PVD) in type 2 diabetes, taking into account other potential risk factors...
  6. ncbi request reprint Cardiovascular risk reduction in diabetes: underemphasised and overdue. Messages from major trials
    A I Adler
    Diabetes Trials Unit, Oxford University, Radcliffe Infirmary
    Clin Med 1:472-7. 2001
    ..There is evidence from clinical trials that select cardiovascular therapies may work better in diabetes, beyond their expected benefit, and may prevent diabetes itself...
  7. ncbi request reprint Treating high blood pressure in diabetes: the evidence
    Amanda I Adler
    Diabetes Trials Unit, Oxford University, Oxford, England
    Semin Vasc Med 2:127-37. 2002
    ..Finally, some drugs used to lower blood pressure have a benefit in individuals not considered hypertensive and appear to have a mechanism of action independent of blood pressure lowering...
  8. ncbi request reprint Risk factors for diabetic neuropathy and foot ulceration
    A Adler
    Diabetes Trials Unit, Nuffield Department of Clinical Medicine, Oxford University, Radcliffe Infirmary, Block II, Woodstock Road, Oxford OX2 6HE, UK
    Curr Diab Rep 1:202-7. 2001
    ..Glycemia is the main modifiable risk factor for PSN, whereas PSN and trauma are the principal potentially modifiable risk factors for the development of foot ulceration...
  9. ncbi request reprint Risk factors for renal dysfunction in type 2 diabetes: U.K. Prospective Diabetes Study 74
    Ravi Retnakaran
    Diabetes Trial Unit, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, UK
    Diabetes 55:1832-9. 2006
    ..Distinct sets of risk factors are associated with the development of these two outcomes, consistent with the concept that they are not linked inexorably in type 2 diabetes...
  10. ncbi request reprint Cost-effectiveness analysis of intensive blood-glucose control with metformin in overweight patients with type II diabetes (UKPDS No. 51)
    P Clarke
    Health Economics Research Centre, Department of Public Health, University of Oxford, Institute of Health Sciences, Headington, Oxford OX3 7LF, UK
    Diabetologia 44:298-304. 2001
    ....
  11. ncbi request reprint Risk factors for myocardial infarction case fatality and stroke case fatality in type 2 diabetes: UKPDS 66
    Richard J Stevens
    Diabetes Trials Unit and the Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, U K
    Diabetes Care 27:201-7. 2004
    ..We investigated whether the risk of MI or stroke being fatal in type 2 diabetes can be estimated using information available around the time diabetes is diagnosed...
  12. ncbi request reprint UKPDS 60: risk of stroke in type 2 diabetes estimated by the UK Prospective Diabetes Study risk engine
    Viti Kothari
    Diabetes Trials Unit, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Radcliffe Infirmary, Oxford, United Kingdom
    Stroke 33:1776-81. 2002
    ..We developed mathematical models to estimate the risk of a first stroke using data from 4549 newly diagnosed type 2 diabetic patients enrolled in the UK Prospective Diabetes Study...
  13. pmc Cost effectiveness of an intensive blood glucose control policy in patients with type 2 diabetes: economic analysis alongside randomised controlled trial (UKPDS 41). United Kingdom Prospective Diabetes Study Group
    A Gray
    Health Economics Research Centre, Department of Public Health, University of Oxford, Institute of Health Sciences, Headington OX3 7LF
    BMJ 320:1373-8. 2000
    ..To estimate the cost effectiveness of conventional versus intensive blood glucose control in patients with type 2 diabetes...
  14. ncbi request reprint An economic evaluation of atenolol vs. captopril in patients with Type 2 diabetes (UKPDS 54)
    A Gray
    Health Economics Research Centre, Department of Public Health, University of Oxford, Institute of Health Sciences, Headington, Oxford OX3 7LF, UK
    Diabet Med 18:438-44. 2001
    ..To compare the net cost of a tight blood pressure control policy with an angiotensin converting enzyme inhibitor (captopril) or beta blocker (atenolol) in patients with Type 2 diabetes...
  15. ncbi request reprint Life-expectancy projection by modelling and computer simulation (UKPDS 46)
    R Stevens
    Diabetes Trials Unit, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Radcliffe Infirmary, Woodstock Road, OX2 6HE, Oxford, UK
    Diabetes Res Clin Pract 50:S5-13. 2000
    ....
  16. doi request reprint Three-year efficacy of complex insulin regimens in type 2 diabetes
    Rury R Holman
    Diabetes Trials Unit, Oxford Centre for Diabetes, Endocrinology and Metabolism, University of Oxford, Oxford, United Kingdom
    N Engl J Med 361:1736-47. 2009
    ..Evidence supporting the addition of specific insulin regimens to oral therapy in patients with type 2 diabetes mellitus is limited...
  17. ncbi request reprint What is the evidence that microalbuminuria is a predictor of cardiovascular disease events?
    Matthew F Yuyun
    Medical Research Council Epidemiology Unit, Department of Medicine and Public Health, School of Clinical Medicine, University of Cambridge, UK
    Curr Opin Nephrol Hypertens 14:271-6. 2005
    ..This review describes recently published studies evaluating the association between microalbuminuria and the development of cardiovascular disease events either in the presence of diabetes or hypertension, or in the population as a whole...
  18. ncbi request reprint Cardiovascular disease and risk factors in three Alaskan Eskimo populations: the Alaska-Siberia project
    Sven O E Ebbesson
    Department of Neurological Surgery, University of Virginia, Charlottesville 22908 0212, USA
    Int J Circumpolar Health 64:365-86. 2005
    ..To determine the prevalence of CVD and to identify and characterize associated risk factors in three distinct Eskimo populations...
  19. pmc Genetic determinants and epidemiology of cystic fibrosis-related diabetes: results from a British cohort of children and adults
    Amanda I Adler
    Addenbrooke s Hospital, Cambridge, UK
    Diabetes Care 31:1789-94. 2008
    ..In this study we documented the incidence of CFRD and evaluated the association between mutations responsible for cystic fibrosis and incident CFRD, while identifying potential risk factors...
  20. ncbi request reprint Simulating the real world of antihyperglycaemic therapies in type 2 diabetes
    Amanda I Adler
    Addenbrooke s Hospital, Cambridge University Hospitals NHS Foundation Trust, UK
    Pharmacoeconomics 24:1-3. 2006
  21. doi request reprint Cross-sectional association between fish consumption and albuminuria: the European Prospective Investigation of Cancer-Norfolk Study
    Chee Tin Christine Lee
    Medical Research Council Epidemiology Unit, Cambridge, United Kingdom
    Am J Kidney Dis 52:876-86. 2008
    ..The aim of this study is to examine the association between fish consumption and albuminuria in individuals with and without diabetes...