Research Topics
Genomes and Genes | Josephine Clare AdamsSummaryAffiliation: University College London Country: UK Publications
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Detail Information
Publications
A role for syndecan-1 in coupling fascin spike formation by thrombospondin-1J C Adams
Medical Research Council Laboratory for Molecular Cell Biology and Department of Biochemistry and Molecular Biology, University College London, London WC1E 6BT, United Kingdom
J Cell Biol 152:1169-82. 2001..These results establish a novel role for syndecan-1 protein in coupling a physiological matrix ligand to formation of a specific matrix contact structure...
Cell-matrix adhesions differentially regulate fascin phosphorylationJ C Adams
Medical Research Council Laboratory for Molecular Cell Biology and Department of Biochemistry and Molecular Biology, University College London, London WC1E 6BT, United Kingdom
Mol Biol Cell 10:4177-90. 1999..These novel results establish matrix-initiated PKC-dependent regulation of fascin phosphorylation at serine 39 as a mechanism whereby matrix adhesion is coupled to the organization of cytoskeletal structure...
cDNA cloning of human muskelin and localisation of the muskelin (MKLN1) gene to human chromosome 7q32 and mouse chromosome 6 B1/B2 by physical mapping and FISHJ C Adams
MRC Laboratory for Molecular Cell Biology and Department of Biochemistry and Molecular Biology, University College London, UK
Cytogenet Cell Genet 87:19-21. 1999..We report that human muskelin is 98% identical with mouse muskelin at the amino acid level. The human muskelin gene is located at 7q32. The mouse muskelin gene maps syntenically at chromosome 6 B1/B2...
The thrombospondin type 1 repeat (TSR) superfamily: diverse proteins with related roles in neuronal developmentJ C Adams
MRC Laboratory for Molecular Cell Biology and Department of Biochemistry and Molecular Biology, University College London, United Kingdom
Dev Dyn 218:280-99. 2000....
Stimulation of fascin spikes by thrombospondin-1 is mediated by the GTPases Rac and Cdc42J C Adams
MRC Laboratory for Molecular Cell Biology and Department of Biochemistry and Molecular Biology, University College London, London WC1E 6BT, United Kingdom
J Cell Biol 150:807-22. 2000..We conclude that fascin is a critical component downstream of Rac and Cdc42 that is needed for actin cytoskeletal organization and cell migration responses to thrombospondin-1...
Regulation of protrusive and contractile cell-matrix contactsJosephine Clare Adams
MRC Laboratory for Molecular Cell Biology and Department of Biochemistry and Molecular Biology, University College London, Gower Street, London WC1E 6BT, UK
J Cell Sci 115:257-65. 2002..I describe contexts for the formation of protrusive or contractile contacts and discuss recent information on the molecular processes by which these contacts are specified, coordinated and regulated at a cellular level...
Cell-matrix contact structuresJ C Adams
Department of Biochemistry and Molecular Biology, University College London, UK
Cell Mol Life Sci 58:371-92. 2001....
Thrombospondins: multifunctional regulators of cell interactionsJ C Adams
MRC Laboratory for Molecular Cell Biology and Department of Biochemistry and Molecular Biology, University College London, Gower Street, London WC1E 6BT, United Kingdom
Annu Rev Cell Dev Biol 17:25-51. 2001....
Muskelin, a novel intracellular mediator of cell adhesive and cytoskeletal responses to thrombospondin-1J C Adams
MRC Laboratory for Molecular Cell Biology and Department of Biochemistry and Molecular Biology, University College London, Gower Street, London WC1E 6BT, UK
EMBO J 17:4964-74. 1998....
Fascins, and their roles in cell structure and functionNina Kureishy
MRC Laboratory for Molecular Cell Biology and Department of Biochemistry and Molecular Biology, University College London
Bioessays 24:350-61. 2002..The supplementary material referred to in this section can be found at http://www.interscience.wiley.com/jpages/0265-9247/suppmat/2002/v24.350.html..
Molecular organisation of cell-matrix contacts: essential multiprotein assemblies in cell and tissue functionJosephine Clare Adams
Department of Cell Biology, NC1 12, Lerner Research Institute, Cleveland Clinic Foundation, 9500 Euclid Avenue, Cleveland, OH 44195, USA
Expert Rev Mol Med 4:1-24. 2002....
