David J Adams

Summary

Affiliation: University of Leeds
Country: UK

Publications

  1. ncbi request reprint Fungal cell wall chitinases and glucanases
    David J Adams
    School of Biochemistry and Microbiology, University of Leeds, Leeds LS2 9JT, UK
    Microbiology 150:2029-35. 2004
  2. pmc Using next-generation sequencing for high resolution multiplex analysis of copy number variation from nanogram quantities of DNA from formalin-fixed paraffin-embedded specimens
    Henry M Wood
    Leeds Institute of Molecular Medicine, St James s University Hospital, Leeds, UK
    Nucleic Acids Res 38:e151. 2010
  3. ncbi request reprint Differential expression and extent of fungal/plant and fungal/bacterial chitinases of Aspergillus fumigatus
    Mariam Taib
    School of Biochemistry and Microbiology, University of Leeds, LS2 9JT, Leeds, UK
    Arch Microbiol 184:78-81. 2005
  4. ncbi request reprint Human non-pregnancy ribonuclease with anti-Kaposi's sarcoma activity
    Moza M A Al-Owais
    Division of Microbiology, School of Biochemistry and Molecular Biology, University of Leeds, Leeds LS2 9JT, UK
    Cancer Lett 176:183-9. 2002
  5. ncbi request reprint Macrocyclic inhibitors of the bacterial cell wall biosynthesis enzyme MurD
    James R Horton
    Departments of Chemistry, University of Leeds, Leeds LS2 9JT, UK
    Bioorg Med Chem Lett 13:1557-60. 2003
  6. ncbi request reprint Disruption of the gene encoding the ChiB1 chitinase of Aspergillus fumigatus and characterization of a recombinant gene product
    Alex K Jaques
    Division of Microbiology, School of Biochemistry and Molecular Biology, University of Leeds, Leeds LS2 9JT, UK
    Microbiology 149:2931-9. 2003
  7. ncbi request reprint Specificity and affinity of natural product cyclopentapeptide inhibitors against A. fumigatus, human, and bacterial chitinases
    Francesco V Rao
    Division of Biological Chemistry and Molecular Microbiology, School of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland
    Chem Biol 12:65-76. 2005

Collaborators

  • David R Westhead
  • Henry M Wood
  • R G Boot
  • Francesco V Rao
  • Mariam Taib
  • James R Horton
  • Alex K Jaques
  • Lars Hesse
  • Moza M A Al-Owais
  • Kenneth J McDowall
  • Kazuro Shiomi
  • John W Pinney
  • Douglas R Houston
  • Johannes M F G Aerts
  • Michael Hodkinson
  • Daan M F van Aalten
  • Satoshi Omura
  • Tanya Parkinson
  • Julieanne M Bostock
  • Christopher A Hitchcock
  • Gemma M Escott
  • Tamo Fukamizo
  • Simon E V Phillips
  • A Peter Johnson
  • Ian Chopra
  • Richard C Barton
  • Colin W G Fishwick
  • Diana Hall
  • Simon J Talbot

Detail Information

Publications8

  1. ncbi request reprint Fungal cell wall chitinases and glucanases
    David J Adams
    School of Biochemistry and Microbiology, University of Leeds, Leeds LS2 9JT, UK
    Microbiology 150:2029-35. 2004
    ....
  2. pmc Using next-generation sequencing for high resolution multiplex analysis of copy number variation from nanogram quantities of DNA from formalin-fixed paraffin-embedded specimens
    Henry M Wood
    Leeds Institute of Molecular Medicine, St James s University Hospital, Leeds, UK
    Nucleic Acids Res 38:e151. 2010
    ..This technique can be valuable in both the analysis of routine diagnostic samples and in examining large repositories of fixed archival material...
  3. ncbi request reprint Differential expression and extent of fungal/plant and fungal/bacterial chitinases of Aspergillus fumigatus
    Mariam Taib
    School of Biochemistry and Microbiology, University of Leeds, LS2 9JT, Leeds, UK
    Arch Microbiol 184:78-81. 2005
    ..Our results provide a basis for future studies with A. fumigatus chitinases, which may lead to the exploitation of these enzymes, or their regulators, in the development of novel drug strategies...
  4. ncbi request reprint Human non-pregnancy ribonuclease with anti-Kaposi's sarcoma activity
    Moza M A Al-Owais
    Division of Microbiology, School of Biochemistry and Molecular Biology, University of Leeds, Leeds LS2 9JT, UK
    Cancer Lett 176:183-9. 2002
    ....
  5. ncbi request reprint Macrocyclic inhibitors of the bacterial cell wall biosynthesis enzyme MurD
    James R Horton
    Departments of Chemistry, University of Leeds, Leeds LS2 9JT, UK
    Bioorg Med Chem Lett 13:1557-60. 2003
    ..Following their preparation, which involved a novel metathesis-based cyclisation as the key step, these systems were found to show good inhibition when assayed against the MurD enzyme...
  6. ncbi request reprint Disruption of the gene encoding the ChiB1 chitinase of Aspergillus fumigatus and characterization of a recombinant gene product
    Alex K Jaques
    Division of Microbiology, School of Biochemistry and Molecular Biology, University of Leeds, Leeds LS2 9JT, UK
    Microbiology 149:2931-9. 2003
    ..fumigatus TIGR database (http://www.tigr.org/)...
  7. ncbi request reprint Specificity and affinity of natural product cyclopentapeptide inhibitors against A. fumigatus, human, and bacterial chitinases
    Francesco V Rao
    Division of Biological Chemistry and Molecular Microbiology, School of Life Sciences, University of Dundee, Dundee DD1 5EH, Scotland
    Chem Biol 12:65-76. 2005
    ..The data show that it may be possible to develop specific chitinase inhibitors based on the argifin/argadin scaffolds...