C L Acerini

Summary

Affiliation: University of Cambridge
Country: UK

Publications

  1. ncbi request reprint Traumatic brain injury induced hypothalamic-pituitary dysfunction: a paediatric perspective
    Carlo L Acerini
    Department of Paediatrics, University of Cambridge, Addenbrooke s Hospital, Level 8 Box 116, Cambridge CB2 2QQ, UK
    Pituitary 10:373-80. 2007
  2. ncbi request reprint Neuroendocrine consequences of traumatic brain injury
    Carlo L Acerini
    Department ofPaediatrics, University of Cambridge, UK
    J Pediatr Endocrinol Metab 21:611-9. 2008
  3. doi request reprint The descriptive epidemiology of congenital and acquired cryptorchidism in a UK infant cohort
    C L Acerini
    Department of Paediatrics, University of Cambridge, Cambridge, UK
    Arch Dis Child 94:868-72. 2009
  4. doi request reprint Head-injury-induced pituitary dysfunction. An old curiosity rediscovered
    Carlo L Acerini
    Department of Paediatrics, University of Cambridge, Box 116, Addenbrooke s Hospital, Cambridge, CB2 2QQ
    Arch Dis Child 93:364-5. 2008
  5. doi request reprint Endocrine sequelae of traumatic brain injury in childhood
    Carlo L Acerini
    Department of Paediatrics, University of Cambridge, Cambridge, UK
    Horm Res 68:14-7. 2007
  6. pmc Endocrine disrupting chemicals: a new and emerging public health problem?
    C L Acerini
    Department of Paediatrics, University of Cambridge, Addenbrooke s Hospital, Cambridge, CB2 2QQ, UK
    Arch Dis Child 91:633-41. 2006
  7. ncbi request reprint The paradigm of pediatric diabetes--art vs. science. Meeting Highlights - 31st Annual ISPAD Meeting, August 31- September 3, 2005, Krakow, Poland
    Carlo L Acerini
    University of Cambridge, Cambridge, UK
    Pediatr Diabetes 6:230-3. 2005
  8. ncbi request reprint Metabolic impact of puberty on the course of type 1 diabetes
    C L Acerini
    Department of Paediatrics, Addenbrooke s Hospital, Cambridge, CB2 2QQ, UK
    Diabetes Metab 27:S19-25. 2001
  9. doi request reprint Insulin sensitivity and body composition in children with classical and nonclassical congenital adrenal hyperplasia
    R M Williams
    Department of Paediatrics, University of Cambridge, Cambridge, UK
    Clin Endocrinol (Oxf) 72:155-60. 2010
  10. pmc Validity of triple- and dual-tracer techniques to estimate glucose appearance
    A Haidar
    Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, United Kingdom
    Am J Physiol Endocrinol Metab 302:E1493-501. 2012

Collaborators

Detail Information

Publications54

  1. ncbi request reprint Traumatic brain injury induced hypothalamic-pituitary dysfunction: a paediatric perspective
    Carlo L Acerini
    Department of Paediatrics, University of Cambridge, Addenbrooke s Hospital, Level 8 Box 116, Cambridge CB2 2QQ, UK
    Pituitary 10:373-80. 2007
    ..We propose that a multidisciplinary approach to follow-up and endocrine assessment is required for the long-term management and rehabilitation of children and adolescents who survive moderate to severe head injury...
  2. ncbi request reprint Neuroendocrine consequences of traumatic brain injury
    Carlo L Acerini
    Department ofPaediatrics, University of Cambridge, UK
    J Pediatr Endocrinol Metab 21:611-9. 2008
    ..We propose that a multidisciplinary approach to follow-up and endocrine assessment is required for the long-term management and rehabilitation of children and adolescents who survive moderate to severe head injury...
  3. doi request reprint The descriptive epidemiology of congenital and acquired cryptorchidism in a UK infant cohort
    C L Acerini
    Department of Paediatrics, University of Cambridge, Cambridge, UK
    Arch Dis Child 94:868-72. 2009
    ..Recent studies in other European countries suggest that the prevalence of congenital cryptorchidism continues to increase. This study aimed to explore the prevalence and natural history of congenital cryptorchidism in a UK centre...
  4. doi request reprint Head-injury-induced pituitary dysfunction. An old curiosity rediscovered
    Carlo L Acerini
    Department of Paediatrics, University of Cambridge, Box 116, Addenbrooke s Hospital, Cambridge, CB2 2QQ
    Arch Dis Child 93:364-5. 2008
  5. doi request reprint Endocrine sequelae of traumatic brain injury in childhood
    Carlo L Acerini
    Department of Paediatrics, University of Cambridge, Cambridge, UK
    Horm Res 68:14-7. 2007
    ..Prospective studies will be needed to determine the incidence, natural history and response to hormone replacement of post-TBI-induced hypopituitarism in children...
  6. pmc Endocrine disrupting chemicals: a new and emerging public health problem?
    C L Acerini
    Department of Paediatrics, University of Cambridge, Addenbrooke s Hospital, Cambridge, CB2 2QQ, UK
    Arch Dis Child 91:633-41. 2006
  7. ncbi request reprint The paradigm of pediatric diabetes--art vs. science. Meeting Highlights - 31st Annual ISPAD Meeting, August 31- September 3, 2005, Krakow, Poland
    Carlo L Acerini
    University of Cambridge, Cambridge, UK
    Pediatr Diabetes 6:230-3. 2005
  8. ncbi request reprint Metabolic impact of puberty on the course of type 1 diabetes
    C L Acerini
    Department of Paediatrics, Addenbrooke s Hospital, Cambridge, CB2 2QQ, UK
    Diabetes Metab 27:S19-25. 2001
    ....
  9. doi request reprint Insulin sensitivity and body composition in children with classical and nonclassical congenital adrenal hyperplasia
    R M Williams
    Department of Paediatrics, University of Cambridge, Cambridge, UK
    Clin Endocrinol (Oxf) 72:155-60. 2010
    ..To understand the potential mechanisms underlying these differences, we assessed insulin sensitivity and body composition in children with classical or nonclassical (late-presenting) CAH compared with normal controls...
  10. pmc Validity of triple- and dual-tracer techniques to estimate glucose appearance
    A Haidar
    Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, United Kingdom
    Am J Physiol Endocrinol Metab 302:E1493-501. 2012
    ..The TT technique tends to outperform slightly the DT technique, but the latter benefits from reduced experimental and computational complexity...
  11. doi request reprint Suspended insulin infusion during overnight closed-loop glucose control in children and adolescents with Type 1 diabetes
    D Elleri
    Department of Paediatrics, University of Cambridge, Cambridge, UK
    Diabet Med 27:480-4. 2010
    ..We assessed an extended interruption of subcutaneous insulin delivery during overnight closed-loop glucose control in children and adolescents with Type 1 diabetes (T1D)...
  12. ncbi request reprint A randomized cross-over trial to identify the optimal use of insulin glargine in prepubertal children using a three-times daily insulin regimen
    E E Fröhlich-Reiterer
    Department of Paediatrics, University of Cambridge, Cambridge, UK
    Diabet Med 24:1406-11. 2007
    ..However, young children may not tolerate such intensive insulin regimens. We investigated the effects of glargine in various three-injections-daily insulin combinations on 24-h glucose control in prepubertal children...
  13. ncbi request reprint Short-term suppression of elevated growth hormone concentrations following insulin-like growth factor 1 administration in young adults with type 1 diabetes does not alter glomerular filtration or albumin excretion rates
    Rachel M Williams
    University of Cambridge, Department of Paediatrics, Cambridge, UK
    Clin Endocrinol (Oxf) 65:439-45. 2006
    ..We tested the hypothesis that restoration of circulating IGF-I concentrations in young adults with T1DM might suppress GH secretion, GFR and urinary albumin excretion...
  14. ncbi request reprint Effects of recombinant human IGF-I/IGF-binding protein-3 complex on glucose and glycerol metabolism in type 1 diabetes
    Tero Saukkonen
    Department of Paediatrics, University of Cambridge, Addenbrooke s Hospital, Hills Road, Cambridge CB2 2QQ, UK
    Diabetes 55:2365-70. 2006
    ..In conclusion, rhIGF-I/IGFBP-3 enhances glucose metabolism by controlling both endogenous glucose output and peripheral glucose uptake...
  15. ncbi request reprint Dose-dependent effects of recombinant human insulin-like growth factor (IGF)-I/IGF binding protein-3 complex on overnight growth hormone secretion and insulin sensitivity in type 1 diabetes
    Tero Saukkonen
    Department of Paediatrics, University of Cambridge, Box 116, Level 8, Addenbrooke s Hospital, Hills Road, Cambridge CB2 2QQ, United Kingdom
    J Clin Endocrinol Metab 89:4634-41. 2004
    ..8 mg/kg.d). Thus, restoration of circulating IGF-I and IGFBP-3 levels with rhIGF-I/IGFBP-3 suppresses GH secretion in adolescents with type 1 diabetes, leading to reduced insulin requirements and improvements in insulin sensitivity...
  16. pmc Overnight closed-loop insulin delivery with model predictive control: assessment of hypoglycemia and hyperglycemia risk using simulation studies
    Malgorzata E Wilinska
    Cambridge University Metabolic Research Laboratories, Institute of Metabolic Science, University of Cambridge, Cambridge, UK
    J Diabetes Sci Technol 3:1109-20. 2009
    ..Additionally, a comparison was made against incidence observed experimentally during open-loop single-night in-clinic studies in young people with type 1 diabetes mellitus (T1DM) treated by continuous SC insulin infusion...
  17. doi request reprint A longitudinal assessment of the effect of inhaled fluticasone propionate therapy on adrenal function and growth in young children with asthma
    R Iles
    Department of Paediatrics, Addenbrooke s NHS Trust, Cambridge, UK
    Pediatr Pulmonol 43:354-9. 2008
    ..Fluticasone proprionate (FP) is increasingly used to treat very young children with asthma. Its safety in terms of effects on the hypothalamic pituitary axis (HPA) and growth in this age group is uncertain...
  18. ncbi request reprint IGF-I and diabetes in adolescence
    D B Dunger
    Department of Paediatrics, John Radcliffe Hospital, Oxford, UK
    Diabetes Metab 24:101-7. 1998
    ....
  19. ncbi request reprint Monitoring of concordance in growth hormone therapy
    R R Kapoor
    Department of Paediatrics, Addenbrooke s Hospital, University of Cambridge, Cambridge, UK
    Arch Dis Child 93:147-8. 2008
    ..Lower concordance was associated with longer duration on GH therapy (p<0.005), lack of choice of delivery device (p<0.005) and short prescription durations (p<0.005), and predicted lower height velocities (p<0.05)...
  20. ncbi request reprint Randomized cross-over trial of insulin glargine plus lispro or NPH insulin plus regular human insulin in adolescents with type 1 diabetes on intensive insulin regimens
    Nuala P Murphy
    Department of Paediatrics, Addenbrooke s Hospital, University of Cambridge, Cambridge, UK
    Diabetes Care 26:799-804. 2003
    ..To compare blood glucose control and incidence of nocturnal hypoglycemia in adolescents with type 1 diabetes on multiple injection regimens managed with either an insulin analog combination or NPH insulin plus regular human insulin...
  21. ncbi request reprint Insulin lispro: a potential role in preventing nocturnal hypoglycaemia in young children with diabetes mellitus
    M E Ford-Adams
    Department of Paediatrics, John Radcliffe Hospital, University of Oxford, Oxford, UK
    Diabet Med 20:656-60. 2003
    ..We examined whether replacing soluble insulin with insulin lispro reduced this risk in children on a three times daily insulin regimen...
  22. ncbi request reprint The effects of a specific growth hormone antagonist on overnight insulin requirements and insulin sensitivity in young adults with Type 1 diabetes mellitus
    R M Williams
    University of Cambridge, Department of Paediatrics, Addenbrooke s Hospital, Hills Rd, Cambridge, UK
    Diabetologia 46:1203-10. 2003
    ..Our aim was to determine the effects of specific growth hormone blockade on insulin sensitivity and lipolysis in young adults with Type 1 diabetes...
  23. doi request reprint Treatment with recombinant human insulin-like growth factor (rhIGF)-I/rhIGF binding protein-3 complex improves metabolic control in subjects with severe insulin resistance
    Fiona M Regan
    University of Cambridge, Department of Pediatrics, Cambridge, United Kingdom
    J Clin Endocrinol Metab 95:2113-22. 2010
    ..We report clinical and physiological outcomes after adjunctive therapy with rhIGF-I/rhIGFBP-3 in five subjects with SIR...
  24. doi request reprint Absorption patterns of meals containing complex carbohydrates in type 1 diabetes
    D Elleri
    University of Cambridge Metabolic Research Laboratories and NIHR Cambridge Biomedical Research Centre, Institute of Metabolic Science, Box 289, Addenbrooke s Hospital, Hills Road, Cambridge CB2 0QQ, UK
    Diabetologia 56:1108-17. 2013
    ..We studied eight young participants with type 1 diabetes to investigate a large low-glycaemic-load (LG) meal and another eight participants to investigate a high-glycaemic-load (HG) meal matched for carbohydrates (121 g)...
  25. doi request reprint Manual closed-loop insulin delivery in children and adolescents with type 1 diabetes: a phase 2 randomised crossover trial
    Roman Hovorka
    Department of Paediatrics, University of Cambridge, Cambridge, UK
    Lancet 375:743-51. 2010
    ..Closed-loop systems link continuous glucose measurements to insulin delivery. We aimed to establish whether closed-loop insulin delivery could control overnight blood glucose in young people...
  26. pmc Simulation environment to evaluate closed-loop insulin delivery systems in type 1 diabetes
    Malgorzata E Wilinska
    Cambridge University Metabolic Research Laboratories, Institute of Metabolic Science, Addenbrooke s Hospital, Cambridge, UK
    J Diabetes Sci Technol 4:132-44. 2010
    ..We present a simulation environment designed to support the development and testing of closed-loop insulin delivery systems in type 1 diabetes mellitus (T1DM)...
  27. doi request reprint Neonatal diabetes and insulin pump therapy
    Kathryn Beardsall
    Department of Paediatrics, University of Cambridge, Cambridge University Hospital NHS Foundation Trust, Cambridge, UK
    Arch Dis Child Fetal Neonatal Ed 96:F223-4. 2011
    ....
  28. doi request reprint Parental attitudes towards overnight closed-loop glucose control in children with type 1 diabetes
    Daniela Elleri
    Department of Paediatrics, University of Cambridge, Cambridge CB2 0QQ, United Kingdom
    Diabetes Technol Ther 12:35-9. 2010
    ..This study examined parental attitudes towards overnight closed-loop (CL) glucose control in children and young people with type 1 diabetes (T1D)...
  29. doi request reprint Effect of delay on measurement of blood glucose levels in young subjects with type 1 diabetes
    Daniela Elleri
    Department of Paediatrics, University of Cambridge, Hills Road, Cambridge CB2 0QQ, UK
    Diabetes Res Clin Pract 86:e31-3. 2009
    ..Blood glucose decreased by 0.47 mmol/L despite samples being collected in fluoride tubes and placed on ice. The extent of reduction differs among subjects, prevailing blood glucose and time-of-day of sample withdrawal...
  30. doi request reprint Insulin-like growth factor I concentrations in infancy predict differential gains in body length and adiposity: the Cambridge Baby Growth Study
    Ken K Ong
    Medical Research Council Epidemiology Unit, Institute of Metabolic Science, Addenbrooke s Hospital, Cambridge, UK
    Am J Clin Nutr 90:156-61. 2009
    ..Formula milk-fed infants show faster rates of growth and weight gain than do breastfed infants, and they have higher concentrations of insulin-like growth factor I (IGF-I)...
  31. ncbi request reprint European Society for Paediatric Endocrinology/Lawson Wilkins Pediatric Endocrine Society consensus statement on diabetic ketoacidosis in children and adolescents
    David B Dunger
    European Society for Paediatric Endocrinology, West Smithfield, London, United Kingdom
    Pediatrics 113:e133-40. 2004
  32. ncbi request reprint A longitudinal study of the effects of a gluten-free diet on glycemic control and weight gain in subjects with type 1 diabetes and celiac disease
    Rakesh Amin
    University Department of Paediatrics, Addenbrooke s Hospital, Cambridge, UK
    Diabetes Care 25:1117-22. 2002
    ..To describe the longitudinal growth characteristics and glycemic control in type 1 diabetic children diagnosed with celiac disease and started on a gluten-free diet (GFD)...
  33. ncbi request reprint Childhood and adolescent diabetes
    David B Dunger
    Department of Paediatrics, Addenbrooke s Hospital, University of Cambridge, Cambridge CB2 2QQ, UK
    Endocr Dev 9:107-20. 2005
    ..The combined treatment is better tolerated and may result in reduced tissue exposure to high levels of 'free' IGF-I. Longer term clinical studies with this IGF-I/IGFBP-3 combination are needed...
  34. doi request reprint Factors controlling testis descent
    Ieuan A Hughes
    Department of Paediatrics, Addenbrooke s Hospital, University of Cambridge, Box 116, Hills Road, Cambridge CB20QQ, UK
    Eur J Endocrinol 159:S75-82. 2008
    ..Appropriate screening programmes and early surgical intervention are the prerequisites to ensure optimal fertility in adulthood and a considerably lessened risk of testis cancer...
  35. pmc Auxological changes in UK survivors of childhood acute lymphoblastic leukaemia treated without cranial irradiation
    R A L Breene
    Department of Paediatric Haematology and Oncology, Addenbrooke s Hospital, Cambridge, CB2 0QQ, UK
    Br J Cancer 104:746-9. 2011
    ..Acute lymphoblastic leukaemia survivors treated historically with protocols including cranial irradiation demonstrate increased weight gain...
  36. ncbi request reprint Hypoglycemia prevalence in prepubertal children with type 1 diabetes on standard insulin regimen: use of continuous glucose monitoring system
    Rakesh Amin
    University Departments of Paediatrics, Addenbrookes Hospital, Cambridge, UK
    Diabetes Care 26:662-7. 2003
    ..To determine hypoglycemia prevalence in prepubertal children on thrice (TID) and twice (BID) daily insulin regimens, using the Medtronic Minimed Continuous Glucose Monitoring System...
  37. ncbi request reprint Hypopituitarism in childhood and adolescence following traumatic brain injury: the case for prospective endocrine investigation
    Carlo L Acerini
    Department of Paediatrics, University of Cambridge, Cambridge, UK
    Eur J Endocrinol 155:663-9. 2006
    ..We urge paediatric endocrinologists, in collaboration with adult endocrinologists, to perform formal prospective research studies in patients suffering from TBI to clarify these questions...
  38. pmc Measurement delay associated with the Guardian RT continuous glucose monitoring system
    C Wei
    MRC Biostatistics Unit, Institute of Public Health, University of Cambridge, Cambridge, UK
    Diabet Med 27:117-22. 2010
    ..Using compartment modelling, we assessed the time delay between blood glucose and sensor glucose measured by the Guardian RT continuous glucose monitoring system in young subjects with Type 1 diabetes (T1D)...
  39. ncbi request reprint Should Angiotensin converting enzyme inhibitors be used in children with type 1 diabetes and microalbuminuria?
    M Q Almerie
    University of Cambridge Department of Paediatrics, Addenbrooke s Hospital, Cambridge, UK
    Arch Dis Child 93:633-5. 2008
  40. pmc ESPE/LWPES consensus statement on diabetic ketoacidosis in children and adolescents
    D B Dunger
    University of Cambridge, Department of Paediatrics, Addenbrooke s Hospital, Level 8, Box 116, Cambridge CB2 2QQ, UK
    Arch Dis Child 89:188-94. 2004
    ..There is agreement that prevention of DKA and reduction of its incidence should be a goal in managing children with diabetes...
  41. doi request reprint Ambulatory blood pressure measurements are related to albumin excretion and are predictive for risk of microalbuminuria in young people with type 1 diabetes
    M L Marcovecchio
    Department of Paediatrics, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
    Diabetologia 52:1173-81. 2009
    ..As microalbuminuria is preceded by a gradual rise in albumin excretion within the normal range, we hypothesised that ambulatory BP (ABP) may be closely related to albumin excretion and progression to microalbuminuria...
  42. doi request reprint Pegvisomant: current and potential novel therapeutic applications
    G N Ajay Thankamony
    University of Cambridge, Department of Paediatrics, Cambridge, UK
    Expert Opin Biol Ther 9:1553-63. 2009
    ..It is currently licensed for the treatment of acromegaly where surgery and medical therapy with somatostatin analogues have failed...
  43. pmc Effects of growth hormone and free fatty acids on insulin sensitivity in patients with type 1 diabetes
    Burak Salgin
    University Department of Pediatrics, Addenbrooke s Hospital, Level 8, Box 116, Cambridge CB2 0QQ, United Kingdom
    J Clin Endocrinol Metab 94:3297-305. 2009
    ..Our aim was to explore the relative contributions of GH and free fatty acids to the development of insulin resistance in patients with T1D...
  44. ncbi request reprint Insulin analog preparations and their use in children and adolescents with type 1 diabetes mellitus
    Harriet L Miles
    Department of Paediatrics, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
    Paediatr Drugs 10:163-76. 2008
    ..Long-term surveillance has been recommended and further carefully designed prospective studies are needed to evaluate the overall benefits and clinical efficacy of insulin analog therapy in children and adolescents with type 1 diabetes...
  45. pmc Prevalence of abnormal lipid profiles and the relationship with the development of microalbuminuria in adolescents with type 1 diabetes
    M Loredana Marcovecchio
    Department of Paediatrics and the Institute of Metabolic Science, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
    Diabetes Care 32:658-63. 2009
    ..To explore the prevalence of lipid abnormalities and their relationship with albumin excretion and microalbuminuria in adolescents with type 1 diabetes...
  46. ncbi request reprint In-utero androgen exposure and 2nd to 4th digit length ratio-comparisons between healthy controls and females with classical congenital adrenal hyperplasia
    J J Buck
    Department of Paediatrics, University of Cambridge, Addenbrooke s Hospital, Cambridge CB2 2QQ, UK
    Hum Reprod 18:976-9. 2003
    ..The relatively longer 4th finger observed in males may be related to increased fetal exposure to androgens influencing the expression of Hox genes...
  47. ncbi request reprint Human metabolic syndrome resulting from dominant-negative mutations in the nuclear receptor peroxisome proliferator-activated receptor-gamma
    David B Savage
    Department of Medicine, Addenbrooke s Hospital, Cambridge, UK
    Diabetes 52:910-7. 2003
    ..Although the condition is rare, the study of humans with dominant-negative mutations in PPAR-gamma can provide important insight into the roles of this nuclear receptor in human metabolism...
  48. pmc Pregnancy insulin, glucose, and BMI contribute to birth outcomes in nondiabetic mothers
    Ken K Ong
    MRC Epidemiology Unit, Institute of Metabolic Science, Cambridge, UK
    Diabetes Care 31:2193-7. 2008
    ..We investigated the effects of normal variations in maternal glycemia on birth size and other birth outcomes...
  49. pmc A family with severe insulin resistance and diabetes due to a mutation in AKT2
    Stella George
    Department of Clinical Biochemistry, University of Cambridge, Addenbrooke s Hospital, Hills Road, Cambridge CB2 2QQ, UK
    Science 304:1325-8. 2004
    ..These findings demonstrate the central importance of AKT signaling to insulin sensitivity in humans...
  50. pmc Anogenital distance from birth to 2 years: a population study
    Ajay Thankamony
    Department of Paediatrics, University of Cambridge, Cambridge, United Kingdom
    Environ Health Perspect 117:1786-90. 2009
    ..5-fold greater in males. It is a reliable marker of androgen and antiandrogen effects in rodent reproductive toxicologic studies. Data on AGD in humans are sparse, with no longitudinal data collected during infancy...
  51. pmc Maternal but not paternal association of ambulatory blood pressure with albumin excretion in young offspring with type 1 diabetes
    M Loredana Marcovecchio
    Department of Paediatrics, University of Cambridge, Cambridge, UK
    Diabetes Care 33:366-71. 2010
    ..Our aim was to assess whether parental ambulatory blood pressure (ABP) was associated with ABP and albumin excretion in young offspring with type 1 diabetes...
  52. ncbi request reprint Cystic fibrosis related diabetes mellitus - diagnostic and management challenges
    Ngee Lek
    Department of Paediatrics, University of Cambridge, Addenbrooke s Hospital, Cambridge, UK
    Curr Diabetes Rev 6:9-16. 2010
    ..We review the current evidence which highlight these diagnostic and management challenges in CFRD...
  53. doi request reprint Traumatic brain injury is a rarely reported cause of growth hormone deficiency
    Anna McDonald
    Department of Pediatrics, University of Cambridge, Cambridge, UK
    J Pediatr 152:590-3. 2008
    ..016). We speculate that TBI-induced GHD may be a neglected phenomenon in childhood, and recommend prospective longitudinal studies to explore its natural history and frequency...