Genomes and Genes
University of Nottingham
Organization: University of Nottingham
- Interventions to reduce Staphylococcus aureus in the management of atopic eczema: an updated Cochrane reviewF J Bath-Hextall
Centre of Evidence Based Dermatology, Faculty of Medicine and Health Science, University of Nottingham, Nottingham, UK
Br J Dermatol 163:12-26. 2010..Although few would dispute the benefit of systemic antibiotics in people with overtly clinically infected eczema, the clinical role of S. aureus in causing inflammatory flares in clinically uninfected eczema is less clear...
- A gastrin transcript expressed in gastrointestinal cancer cells contains an internal ribosome entry siteA M Grabowska
Division of Pre Clinical Oncology, School of Medical and Surgical Sciences, University of Nottingham, Nottingham, UK
Br J Cancer 98:1696-703. 2008....
- A novel physiological culture system that mimics luteal angiogenesisR S Robinson
School of Veterinary Medicine and Science and School of Biosciences, University of Nottingham, Sutton Bonington Campus, Loughborough, Leics LE12 5RD, UK
Reproduction 135:405-13. 2008..001). In conclusion, the successful development of endothelial cell networks in vitro provides a new opportunity to elucidate the physiological control of the angiogenic process in the developing CL...
- Cochrane Schizophrenia GroupClive E Adams
Division of Psychiatry, University of Nottingham, UK
Schizophr Bull 34:259-65. 2008
- Elevated CD16 expression by monocytes from patients with tumor necrosis factor receptor-associated periodic syndromeIan Todd
Division of Immunology, University of Nottingham, Queen s Medical Centre, Nottingham, UK
Arthritis Rheum 56:4182-8. 2007..The aim of this study was to investigate whether the expression of circulating CD16+ monocytes is affected in patients with TRAPS...
- Commentary: preventing colorectal cancer with aspirin what next?Richard Logan
Division of Epidemiology and Public Health, Queens Medical Centre, University of Nottingham, Nottingham NG7 2UH, UK
Int J Epidemiol 36:960-2. 2007
- Cognitive abilities as predictors of safety to drive in people with multiple sclerosisN B Lincoln
Institute of Work, Health and Organisations, University of Nottingham, Nottingham NG7 2RD, UK
Mult Scler 14:123-8. 2008..An equation was generated using discriminant function analysis with an overall predictive accuracy of 88% (Sensitivity for pass 90%, Specificity 90%). Cognitive abilities were predictors of safety to drive in people with MS...
- 'Am I normal?' Teenagers, sexual health and the internetKevin James Harvey
School of English Studies, University of Nottingham, University Park, University Boulevard, Nottingham, Nottinghamshire NG7 2RD, UK
Soc Sci Med 65:771-81. 2007....
- Stroke rehabilitation: evidence-based or evidence-tinged?Marion F Walker
Division of Rehabilitation and Ageing, University of Nottingham, Queen s Medical Centre, UK
J Rehabil Med 39:193-7. 2007..Technological and capacity-building advances, along with newly developing stroke research networks, will ensure that the future of stroke rehabilitation is strong and progressing towards becoming truly evidence-based...
- Theoretical optimization of multi-echo fMRI data acquisitionP A Gowland
Sir Peter Mansfield Magnetic Resonance Centre, School of Physics and Astronomy, University of Nottingham, UK
Phys Med Biol 52:1801-13. 2007..It is also shown that the optimal sequence will remain optimum or close to optimum irrespective of whether there are physiological noise contributions...
- The iceberg of celiac disease: what is below the waterline?Joe West
Division of Epidemiology and Public Health, University of Nottingham, Medical School, Queen s Medical Centre, Nottingham, United Kingdom
Clin Gastroenterol Hepatol 5:59-62. 2007..We explored the relationships between anti-tissue transglutaminase antibody and indirect measures of malabsorption and disease activity in people with undetected celiac disease...
- Does cause of deafness influence outcome after cochlear implantation in children?Thomas P Nikolopoulos
Department of Otorhinolaryngology, Athens University, Hippokration Hospital, Athens, Greece
Pediatrics 118:1350-6. 2006..The objective of this study was to evaluate long-term speech perception abilities of comparable groups of postmeningitic and congenitally deaf children after cochlear implantation...
- Pharmacogenetics, the next challenge for pharmacy?Jessica P Clemerson
Centre for Pharmacy, Health and Society, University of Nottingham, University Park, Nottingham NG7 2RD, UK
Pharm World Sci 28:126-30. 2006..This commentary discusses potential new roles for pharmacists involving pharmacogenetic technologies, giving attention to the way the profession may need to adapt to accommodate these...
- A case of a "fragile" oesophagusG K Anagnostopoulos
Wolfson Digestive Diseases Centre, University Hospital, Nottingham, UK
Gut 55:1495, 1511. 2006
- Effect of setting, monitoring intensity and patient experience on anticoagulation control: a systematic review and meta-analysis of the literatureG Dolan
Department of Haematology, QMC Campus, Nottingham University Hospitals, Nottingham, UK
Curr Med Res Opin 24:1459-72. 2008....
- The reversible P2Y antagonist cangrelor influences the ability of the active metabolites of clopidogrel and prasugrel to produce irreversible inhibition of platelet functionN L Dovlatova
Cardiovascular Medicine, University of Nottingham, Nottingham, UK
J Thromb Haemost 6:1153-9. 2008..At the cessation of cangrelor infusion, patients are likely to receive clopidogrel or prasugrel as a means of maintaining antiplatelet therapy...
- WHO wants safer medicines for childrenImti Choonara
Academic Division of Child Health, University of Nottingham, The Medical School, Derbyshire Children s Hospital, Uttoxeter Road, Derby DE22 3DT, UK
Arch Dis Child 93:456-7. 2008
- Coping with infertility online: an examination of self-help mechanisms in an online infertility support groupSumaira H Malik
Institute of Work, Health and Organisations, University of Nottingham, UK
Patient Educ Couns 81:315-8. 2010..To examine communication within an online infertility support group...
- Strategies for improving patient recruitment to focus groups in primary care: a case study reflective paper using an analytical frameworkJane V Dyas
National Institute for Health Research, Research Design Service East Midlands, Tower Building, University Park, Nottingham, NG7 2RD, UK
BMC Med Res Methodol 9:65. 2009..The aim of this paper is to reflect on recruitment to a focus group study comparing the methods used with existing evidence using a resource for research recruitment, PROSPeR (Planning Recruitment Options: Strategies for Primary Care)...
- Cholesterol profile in people with newly diagnosed coeliac disease: a comparison with the general population and changes following treatmentNina R Lewis
Division of Epidemiology and Public Health, Medical School, Queen s Medical Centre, University of Nottingham, Nottingham NG7 2UH, UK
Br J Nutr 102:509-13. 2009..Any increase in risk of IHD or stroke in people with coeliac disease is unlikely due to an adverse cholesterol profile either before diagnosis or after treatment with a gluten-free diet...
- Sensitive absorptive refocused scalar correlation NMR spectroscopy in solidsDaniel Lee
School of Chemistry, University of Nottingham, University Park, Nottingham, UKNG7 2RD
Phys Chem Chem Phys 11:3547-53. 2009..Its utility is demonstrated via assignments of the carbon-13 MAS spectra of progesterone at natural abundance and of the polymer phase of 50%-U-(13)C-CsC(60)...
- Can quantitative three-dimensional power Doppler angiography be used to predict ovarian hyperstimulation syndrome?K Jayaprakasan
Nottingham University Research and Treatment Unit in Reproduction NURTURE, Division of Human Development, School of Clinical Sciences, Queen s Medical Centre, University of Nottingham, Nottingham, UK
Ultrasound Obstet Gynecol 33:583-91. 2009..To test the hypothesis that ovarian vascularity is increased in women developing ovarian hyperstimulation syndrome (OHSS) and to assess its value as a predictor of OHSS during in-vitro fertilization (IVF)...
- Help-seeking for mental health problems among Chinese: the application and extension of the theory of planned behaviorPhoenix K H Mo
Institute of Work, Health and Organisations, University of Nottingham, Nottingham NG8 1BB, UK
Soc Psychiatry Psychiatr Epidemiol 44:675-84. 2009..Implications on the enhancement of mental health awareness and the promotion of mental health services through a social-cognitive approach were highlighted...
- Substrate binding in the FAD-dependent hydroxynitrile lyase from almond provides insight into the mechanism of cyanohydrin formation and explains the absence of dehydrogenation activityIngrid Dreveny
Institut für Molekulare Biowissenschaften, Karl Franzens Universität, Humboldtstrasse 50 III, A 8010 Graz, Austria
Biochemistry 48:3370-7. 2009..On the basis of the difference in substrate binding geometry between the FAD-dependent HNL from almond and the related oxidases, we can rationalize why the HNL does not act as an oxidase...
- On the use of drawing tasks in neuropsychological assessmentAlastair D Smith
School of Psychology, University of Nottingham, Nottingham, UK
Neuropsychology 23:231-9. 2009..PsycINFO Database Record (c) 2009 APA, all rights reserved)...
- Seroprevalence of and risk factors for Toxoplasma gondii antibodies among asymptomatic blood donors in EgyptHany M Elsheikha
Division of Veterinary Medicine, The School of Veterinary Medicine and Science, The University of Nottingham, Sutton Bonington Campus, Leicestershire, UK
Parasitol Res 104:1471-6. 2009..82 [95% CI 18.62-350.81], P < 0.0001) or being non-educated (adjusted OR 32.25 [95% CI 7.46-139.44], P < 0.0001). These findings highlight that T. gondii is prevalent among blood donors in Egypt...
- Parental reporting of suspected adverse drug reactions in children in Lagos, NigeriaK A Oshikoya
Pharmacology Department, Lagos State University College of Medicine, Ikeja, Lagos, Nigeria
Arch Dis Child 94:469-73. 2009..To determine the feasibility of parental reporting of suspected adverse drug reactions (ADRs) to community pharmacies in Nigeria...
- Quality improvement in primary care mental health practice. A case for political intervention?Hugh Middleton
Associate Professor, School of Sociology and Social Policy, University of Nottingham, UK
Qual Prim Care 16:419-24. 2008....
- The Driver Prioritisation Questionnaire: exploring drivers' self-report visual priorities in a range of driving scenariosPanos Konstantopoulos
Department of Psychology, University of Nottingham, Nottingham, UK
Accid Anal Prev 40:1925-36. 2008..It appears that during the learning process the novice drivers did not adopt the prioritisation strategies seen in driving instructors. This has important implications for the teaching of visual skills in driving...
- Are interventions to enhance communication performance in allied health professionals effective, and how should they be delivered? Direct and indirect evidenceRuth Parry
University of Nottingham, Institute for Science and Society, Law and Social Sciences Building West Wing, University Park, Nottingham NG7 2RD, UK
Patient Educ Couns 73:186-95. 2008..2) To summarise indirect evidence pertinent to design, delivery, effects, and evaluation of such interventions...
- Polypyrimidine tract binding protein regulates IRES-mediated gene expression during apoptosisMartin Bushell
School of Pharmacy, University of Nottingham, University Park, Nottingham NG7 2RD, United Kingdom
Mol Cell 23:401-12. 2006..Finally, the data showed that polypyrimidine tract binding protein (PTB, a known IRES trans-acting factor or ITAF) is pivotal in regulating the apoptotic process by controlling IRES function...
- Severe hyponatraemia in medical in-patients: aetiology, assessment and outcomeJ A Clayton
Division of Therapeutics and Molecular Medicine, Queen s Medical Centre, Nottingham NG7 2UH
QJM 99:505-11. 2006..Hyponatraemia is the most commonly identified electrolyte abnormality. Published data on severe hyponatraemia in general medical in-patients is lacking...
- Stability of recombinant 2 S albumin allergens in vitroG J Murtagh
School of Life and Environmental Sciences, University of Nottingham, University Park, UK
Biochem Soc Trans 30:913-5. 2002....
- Abscission, dehiscence, and other cell separation processesJeremy A Roberts
Division of Plant Science, School of Biosciences, Sutton Bonington Campus, University of Nottingham, Loughborough, Leics LE12 5RD, United Kingdom
Annu Rev Plant Biol 53:131-58. 2002..The opportunities for using this information to manipulate cell separation for the benefit of agriculture and horticulture are evaluated...
- The involvement of smooth muscle P2X receptors in the prolonged vasorelaxation response to purine nucleotides in the rat mesenteric arterial bedV Ralevic
School of Biomedical Sciences, University of Nottingham Medical School, Queen s Medical Centre, Nottingham NG7 2UH, UK
Br J Pharmacol 135:1988-94. 2002..Caution should be applied when using sodium deoxycholate to remove the endothelium because of possible damage caused by the detergent to receptors and/or the vascular smooth muscle...
- Do the attitudes and beliefs of young teenagers towards general practice influence actual consultation behaviour?R Churchill
Division of General Practice, School of Community Health Sciences, Trent Institute for Health Services Research, Faculty of Medicine and Health Sciences, Queen s Medical Centre, Nottingham
Br J Gen Pract 50:953-7. 2000..We report the results of a study examining links between potential attitudinal barriers and actual help-seeking behaviour...
- Smoking and hepato-biliary diseaseR F Logan
Division of Public Health and Epidemiology, University Hospital, Queen s Medical Centre, Nottingham, UK
Eur J Gastroenterol Hepatol 12:863-7. 2000..As smoking is so prevalent in many countries, the public health impact of even a weak causal relationship would be considerable...
- What determines the rate of sequence evolution?J F Brookfield
Institute of Genetics, University of Nottingham, Queens Medical Centre, Nottingham, NG7 2UH, UK
Curr Biol 10:R410-R0411. 2000..However, two recent studies have shown that rapid evolution of amino-acid sequence can also be congruent with neutrality...
- Protection of corneal endothelium from irrigation damage: a comparison of sodium hyaluronate and hydroxypropylmethylcelluloseH S Dua
Department of Ophthalmology, Queen s Medical Centre, University Hospital Nottingham, UK
Eye (Lond) 14:88-92. 2000..To compare the endothelial protection of sodium hyaluronate and hydroxypropylmethylcellulose against endothelial damage induced by irrigation...
- Association between teenage pregnancy rates and the age and sex of general practitioners: cross sectional survey in Trent 1994-7J Hippisley-Cox
Division of General Practice, Medical School, Queen s Medical Centre, Nottingham NG7 2UH
BMJ 320:842-5. 2000..To examine variations in teenage pregnancy rates in Trent region and to determine possible associations with local general practice characteristics such as the age and sex of the doctors...
- Spatial and temporal patterns in final amendments to provisional disease countsM Smallman-Raynor
Department of Geography, University of Nottingham, England
J Public Health Manag Pract 5:68-83. 1999..Practitioners at the state and community levels need to be aware of the temporal and spatial instabilities in such provisional data if they are used to provide early warning of contemporary health aberrations...
- An audit of emergency abdominal aortic aneurysm repair to establish the necessity for an emergency vascular surgical rotaD N Lobo
Derbyshire Royal Infirmary, Derby, UK
Ann R Coll Surg Engl 81:156-60. 1999..The mortality figures compare favourably with other published series. As the results of the two groups were similar, there is currently no need for vascular surgeons to be routinely available for acute AAA surgery at our hospital...
- Quality of full and final publications reporting acute stroke trials: a systematic reviewF J Bath
Stroke Group, Department of Medicine, King s College School of Medicine and Dentistry, London, UK
Stroke 29:2203-10. 1998..We report on the quality of the final reports of randomized controlled trials (RCTs) of drug therapies assessed in acute stroke...
- The interaction between nutritional status and growth hormone in young cattle: differential responsiveness of fat and protein metabolismJ M Dawson
School of Biology, University of Nottingham, Loughborough, UK
Br J Nutr 79:275-86. 1998..We conclude that lipid and protein metabolism are differentially responsive to GH and nutritional status...
- A perspective on lifelong learning and its implications for nursesS E Maslin-Prothero
Postgraduate Division of Nursing, University of Nottingham, Queen s Medical School, UK
Nurse Educ Today 17:431-6. 1997..The aim of this paper is to explore the literature on lifelong learning and then relate how lifelong learning might contribute to both nurses and nurse education...
- There is no evidence for a 'no overt subject' stage in early child Spanish: a note on Grinstead (2000)Javier Aguado-Orea
Department of Psychology, University of Nottingham, University Park, Nottingham, NG7 2RD, UK
J Child Lang 29:865-74. 2002..They thus provide no support for the claim that there is a 'no overt subject' stage in early child Spanish...
- Costs of flexible sigmoidoscopy screening for colorectal cancer in the United KingdomDavid K Whynes
School of Economics, University of Nottingham, UK
Int J Technol Assess Health Care 19:384-95. 2003..Amongst the many possible protocols is once-only screening by means of flexible sigmoidoscopy. This protocol is currently being investigated in a UK multicenter trial and the study provides estimates of the expected resource costs...
- The future for child healthcare provision within general practiceD Sowden
Arch Dis Child 89:115-6. 2004
- Randomised trial of high frequency oscillatory ventilation or conventional ventilation in babies of gestational age 28 weeks or less: respiratory and neurological outcomes at 2 yearsN Marlow
Queen s Medical Centre, Nottingham NG7 2UH, UK
Arch Dis Child Fetal Neonatal Ed 91:F320-6. 2006..The long term outcome of children entered into neonatal trials of high frequency oscillatory ventilation (HFOV) or conventional ventilation (CV) has been rarely studied...
- Opinion: antibody-based therapies for malariaRichard J Pleass
Institute of Genetics, School of Biology, University of Nottingham, Nottingham, NG7 2UH, UK
Nat Rev Microbiol 3:893-9. 2005..In this article, we discuss the possible therapeutic uses of antibodies in the treatment and prevention of malaria...
- Cyclooxygenase-2 inhibitorsChristopher J Hawkey
Wolfson Digestive Diseases Centre, University of Nottingham, University Hospital, UK
Curr Opin Gastroenterol 21:660-4. 2005..The purpose of this review is to summarize new information regarding the use of selective inhibitors of the cyclooxygenase-2 enzyme, emphasizing recent developments regarding cardiovascular risk...
- Unusual genetic organization of a functional type I protein secretion system in Neisseria meningitidisKarl G Wooldridge
Division of Microbiology and Infectious Diseases, Queens Medical Centre, Nottingham NG7 2UH, United Kingdom
Infect Immun 73:5554-67. 2005..We show that genes scattered in the meningococcal genome encode a functional TOSS required for secretion of the meningococcal RTX proteins...
- Sensitivity to further endocrine therapy is retained following progression on first-line fulvestrantJ F R Robertson
Unit of Surgery, City Hospital, NG5 1PB, Nottingham, UK
Breast Cancer Res Treat 92:169-74. 2005..Results from this questionnaire-based study suggest that postmenopausal women with advanced breast cancer who respond to first-line fulvestrant or tamoxifen retain sensitivity to subsequent endocrine therapy...
- A comparison of the quality of life of hearing-impaired people as estimated by three different utility measuresGarry R Barton
MRC Institute of Hearing Research, University Park, Nottingham, UK
Int J Audiol 44:157-63. 2005..36 to 0.58). This suggests that different utility measures will provide different estimates of the effectiveness of hearing aid provision...
- Optimised two-dimensional electrophoresis procedures for the protein characterisation of structural tissuesAndrew Hopkinson
University of Nottingham Division of Ophthalmology and Visual Sciences, EENT Centre, UK
Proteomics 5:1967-79. 2005..Samples were either cup-loaded onto rehydrated HED-containing strips or rebuffered into HED-containing buffer followed by in-gel rehydration...
- Methodological considerations in rat brain BOLD contrast pharmacological MRIC A Steward
Institute of Neuroscience, Sir Peter Mansfield Magnetic Resonance Centre, University of Nottingham, University Park, Nottingham, NG7 2RD, UK
Psychopharmacology (Berl) 180:687-704. 2005..The present review is primarily aimed at psychopharmacologists with no previous experience of phMRI, who are interested in the practical aspects that phMRI studies entail...
- The National Patient Safety AgencyT Stephenson
Queen s Medical Centre, Nottingham NG7 2UH, UK
Arch Dis Child 90:226-8. 2005
- Measurement of cervical spinal cord cross-sectional area by MRI using edge detection and partial volume correctionChristopher R Tench
Division of Clinical Neurology, University Hospital, University of Nottingham, Nottingham, UK
J Magn Reson Imaging 21:197-203. 2005....
- Health-related behavior and beliefs of pregnant smokersCheryl Haslam
Institute of Work, Health and Organisations, University of Nottingham, Nottingham, England
Health Psychol 23:486-91. 2004..Infants of smokers may be placed at an intrauterine disadvantage, not only in terms of smoking, but also in terms of nutrition...
- Immunohistochemical localization of the bone morphogenetic protein receptors in the porcine ovaryRuth L Quinn
Division of Animal Physiology, University of Nottingham, UK
J Anat 205:15-23. 2004..The expression of BMPRs by fetal ovaries may be related to follicle formation, whereas expression in pre- and post-pubertal animals indicates BMPs are involved in regulating porcine ovarian follicle growth...
- Working part-time: achieving a successful 'work-life' balance?Tracey Warren
School of Sociology and Social Policy, University of Nottingham
Br J Sociol 55:99-122. 2004..In this way, we would be in a better position to begin to assess all the benefits and disadvantages associated with working part-time and with other work-life balancing strategies...
- Conservation and antigenic cross-reactivity of the transferrin-binding proteins of Haemophilus influenzae, Actinobacillus pleuropneumoniae and Neisseria meningitidisJ Holland
Department of Pharmaceutical Sciences, University of Nottingham, UK
Microbiology 142:3505-13. 1996..These data demonstrate the existence of shared epitopes on the Tbps of H. influenzae, N. meningitidis and A. pleuropneumoniae despite their transferrin species specificity...
- DNA methylation programming to oocyte environmentKevin Sinclair; Fiscal Year: 2007..abstract_text> ..
- Role of Oxidative Mechanisms in the Toxicity of MetalsSIMON AVERY; Fiscal Year: 2007....