Research Topics
| O H FrancoSummaryAffiliation: Unilever Research Country: UK Publications
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Detail Information
Publications
Associations of diabetes mellitus with total life expectancy and life expectancy with and without cardiovascular diseaseOscar H Franco
Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands
Arch Intern Med 167:1145-51. 2007..We aimed to calculate the association of diabetes after age 50 years with life expectancy and the number of years lived with and without CVD...
Ten commandments for the future of ageing research in the UK: a vision for actionOscar H Franco
BMC Geriatr 7:10. 2007....
Primary prevention of cardiovascular disease: cost-effectiveness comparisonOscar H Franco
Department of Public Health, University Medical Center Rotterdam, 50 Dr Molewaterplein, 3000 CA Rotterdam, Zuid Holland
Int J Technol Assess Health Care 23:71-9. 2007..The aim of this study was to evaluate the cost-effectiveness of four risk-lowering interventions (smoking cessation, antihypertensives, aspirin, and statins) in primary prevention of cardiovascular disease...
Effectiveness calculation in economic analysis: the case of statins for cardiovascular disease preventionOscar H Franco
Department of Public Health, Erasmus MC, University Medical Centre Rotterdam, Netherlands
J Epidemiol Community Health 60:839-45. 2006..This report aimed to evaluate the calculation of estimates of effectiveness in cost effectiveness analyses of statins for cardiovascular disease prevention...
The future of metabolic syndrome and cardiovascular disease prevention: polyhype or polyhope? Tales from the polyeraO H Franco
Unilever Corporate Research, Colworth Park, Sharnbrook, Bedfordshire, MK441LQ, UK
Horm Metab Res 39:627-31. 2007..Polyproducts from the polyera in true populations might hide unexpected polyinteractions. In the polyera, polytrials will need to establish benefits, harms, and costs...
Blood pressure in adulthood and life expectancy with cardiovascular disease in men and women: life course analysisOscar H Franco
Department of Public Health, Erasmus MC, University Medical Center Rotterdam, PO Box 1738, 3000 DR Rotterdam, The Netherlands
Hypertension 46:280-6. 2005..This effect is larger than estimated previously and affects both sexes similarly. Our findings underline the tremendous importance of preventing high blood pressure and its consequences in the population...
Dietary nutrient intakes and skin-aging appearance among middle-aged American womenMaeve C Cosgrove
Corporate Research, Unilever Colworth Park, Bedford, United Kingdom
Am J Clin Nutr 86:1225-31. 2007..Nutritional factors play a key role in normal dermatologic functioning. However, little is known about the effects of diet on skin-aging appearance...
Self-Rated Health in middle-aged and elderly Chinese: distribution, determinants and associations with cardio-metabolic risk factorsNazanin Haseli-Mashhadi
Unilever R and D, Colworth Science Park, Sharnbrook, Bedfordshire, UK
BMC Public Health 9:368. 2009..We aimed to evaluate the distribution and factors associated with SRH and its association with biomarkers of cardio-metabolic diseases among middle-aged and elderly Chinese...
Cost effectiveness of statins in coronary heart diseaseOscar H Franco
Department of Public Health, Erasmus MC, University Medical Centre Rotterdam, PO Box 1738, office Ee 2006, 3000 DR Rotterdam, Netherlands
J Epidemiol Community Health 59:927-33. 2005..This article reviewed cost effectiveness analyses of statins and sought to synthesise cost effectiveness ratios for categories of risk of coronary heart disease and age...
The Polymeal: a more natural, safer, and probably tastier (than the Polypill) strategy to reduce cardiovascular disease by more than 75%Oscar H Franco
Department of Public Health, Erasmus MC University Medical Centre Rotterdam, PO Box 1738, 3000 DR Rotterdam, Netherlands
BMJ 329:1447-50. 2004..The objective of this study was to identify a tastier and safer alternative to the Polypill: the Polymeal...
Living healthier for longer: comparative effects of three heart-healthy behaviors on life expectancy with and without cardiovascular diseaseWilma J Nusselder
Department of Public Health, Erasmus MC, University Medical Center Rotterdam, PO Box 2040, 3000 CA Rotterdam, Rotterdam, The Netherlands
BMC Public Health 9:487. 2009..We aimed to calculate and compare the effects of non-smoking, normal weight and physical activity in middle-aged populations on life expectancy with and without cardiovascular disease...
The polypill: at what price would it become cost effective?Oscar H Franco
Department of Public Health, Erasmus MC, University Medical Centre Rotterdam, 3000 DR Rotterdam, Netherlands
J Epidemiol Community Health 60:213-7. 2006..The aim of this study was to determine the maximum price of the polypill for it to be a cost effective alternative in the primary prevention of cardiovascular disease...
Effects of physical activity on life expectancy with cardiovascular diseaseOscar H Franco
Department of Public Health, Erasmus MC University Medical Center Rotterdam, Rotterdam, The Netherlands
Arch Intern Med 165:2355-60. 2005..Our objective was to calculate the consequences of different physical activity levels after age 50 years on total life expectancy and life expectancy with and without cardiovascular disease...
The relation between non-occupational physical activity and years lived with and without disabilityW J Nusselder
Department of Public Health, Erasmus University Medical Center, Rotterdam, PO Box 2040, 3000 CA Rotterdam, The Netherlands
J Epidemiol Community Health 62:823-8. 2008..The effects of non-occupational physical activity were assessed on the number of years lived with and without disability between age 50 and 80 years...
Trajectories of entering the metabolic syndrome: the framingham heart studyOscar H Franco
Unilever Corporate Research, Sharnbrook, UK
Circulation 120:1943-50. 2009..We evaluated the progression of the metabolic syndrome (MetS) and its components, the trajectories followed by individuals entering MetS, and the manner in which different trajectories predict cardiovascular disease and mortality...
Physical activity and life expectancy with and without diabetes: life table analysis of the Framingham Heart StudyJacqueline T Jonker
Department of Public Health, Erasmus Medical Center, P.O. Box 1738, 3000 DR, Rotterdam, Netherlands
Diabetes Care 29:38-43. 2006..2 (-0.8 to 0.3) years, respectively. CONCLUSIONS: Moderately and highly active people have a longer total life expectancy and live more years free of diabetes than their sedentary counterparts but do not spend more years with diabetes...
Sleep quality in middle-aged and elderly Chinese: distribution, associated factors and associations with cardio-metabolic risk factorsNazanin Haseli-Mashhadi
Unilever R and D, Colworth Science Park, Sharnbrook, Bedfordshire, UK
BMC Public Health 9:130. 2009..However, limited information exists on the distribution and determinants of sleep quality and its associations with cardio-metabolic risk factors in Chinese populations. We aimed to evaluate this in the current study...
Changing course in ageing research: The healthy ageing phenotypeOscar H Franco
Unilever Corporate Research, Colworth Park, Sharnbrook, Bedfordshire, UK
Maturitas 63:13-9. 2009..Furthermore it is fundamental that scientific findings are translated incessantly into clear messages delivered to governmental institutions, the industry and society in general...
Dietary patterns and risk of mortality from cardiovascular disease, cancer, and all causes in a prospective cohort of womenChristin Heidemann
Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02215, USA
Circulation 118:230-7. 2008..The impact of overall dietary patterns that reflect actual eating behaviors on mortality caused by cardiovascular or other chronic diseases is largely unknown...
Adiponectin and metabolic syndrome in middle-aged and elderly ChineseJing Wang
Key Laboratory of Systems Biology, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Graduate School of the Chinese Academy of Sciences, Shanghai, China
Obesity (Silver Spring) 16:172-8. 2008..The aim of this study was to investigate the association between plasma adiponectin levels and MetS in middle-aged and elderly Chinese from both urban and rural areas of northern and southern China...
Combined impact of lifestyle factors on mortality: prospective cohort study in US womenRob M van Dam
Department of Nutrition, Harvard School of Public Health, 665 Huntington Ave, Boston, MA 02115, USA
BMJ 337:a1440. 2008..To evaluate the impact of combinations of lifestyle factors on mortality in middle aged women...
Insulin resistance and depressive symptoms in middle-aged and elderly Chinese: findings from the Nutrition and Health of Aging Population in China StudyAn Pan
Key Laboratory of Systems Biology, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Graduate School of the Chinese Academy of Sciences, Shanghai, China
J Affect Disord 109:75-82. 2008..Nevertheless, only a few studies have explored the association between insulin resistance and depression with contradictory results, and none have been conducted in Chinese populations...
Elevated retinol-binding protein 4 levels are associated with metabolic syndrome in Chinese peopleQibin Qi
Key Laboratory of Systems Biology, Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Graduate School of the Chinese Academy of Sciences, Shanghai 200031, China
J Clin Endocrinol Metab 92:4827-34. 2007..High retinol-binding protein 4 (RBP4) is thought to be associated with insulin resistance in humans. However, evidence from large-scale populations about the relationship between RBP4 and metabolic diseases is scarce...
Higher dietary intake of lignans is associated with better cognitive performance in postmenopausal womenOscar H Franco
Julius Center for Health Sciences and Primary Care, University Medical Center, Utrecht, The Netherlands
J Nutr 135:1190-5. 2005..02 (1.11-3.71)]. Isoflavone intake was not related to cognitive function. From our results we conclude that higher dietary intake of lignans is associated with better cognitive function in postmenopausal women...
Prevalence and geographic disparity of depressive symptoms among middle-aged and elderly in ChinaAn Pan
Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Graduate School of the Chinese Academy of Sciences, Shanghai, China
J Affect Disord 105:167-75. 2008..To evaluate the prevalence of and risk factors for depressive symptoms among middle-aged and elderly Chinese in northern and southern China...
Distributions of C-reactive protein and its association with metabolic syndrome in middle-aged and older Chinese peopleXingwang Ye
Institute for Nutritional Sciences, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences and Graduate School of the Chinese Academy of Sciences, Shanghai, China
J Am Coll Cardiol 49:1798-805. 2007..We evaluated the distributions of C-reactive protein (CRP) and its association with metabolic syndrome (MetS) in middle-aged and older Chinese people...
