Joseph Meirion Thomas

Summary

Country: UK

Publications

  1. ncbi request reprint Dr. Herbert Lumley Snow, MD, MRCS (1847-1930): the original champion of elective lymph node dissection in melanoma
    Susan J Neuhaus
    FRCP, Sarcoma and Melanoma Unit, The Royal Marsden Hospital, Fulham Road, London, SW3 6JJ, UK
    Ann Surg Oncol 11:875-8. 2004
  2. ncbi request reprint Retroperitoneal sarcoma
    J M Thomas
    Royal Marsden Hospital, Fulham Road, London, UK
    Br J Surg 94:1057-8. 2007
  3. ncbi request reprint Prognostic false-positivity of the sentinel node in melanoma
    J Meirion Thomas
    Royal Marsden Hospital and Imperial College, London, UK
    Nat Clin Pract Oncol 5:18-23. 2008
  4. ncbi request reprint Caution with sentinel node biopsy in cutaneous melanoma
    J M Thomas
    Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK
    Br J Surg 93:129-30. 2006
  5. doi request reprint Concerns relating to the conduct and statistical analysis of the Multicenter Selective Lymphadenectomy Trial (MSLT-1) in patients with melanoma
    Joseph Meirion Thomas
    Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK
    J Plast Reconstr Aesthet Surg 62:442-6. 2009
  6. ncbi request reprint Selective lymphadenectomy in sentinel node-positive patients may increase the risk of local/in-transit recurrence in malignant melanoma
    J M Thomas
    Melanoma and Sarcoma Unit, Department of Surgery, The Royal Marsden Hospital, 203 Fulham Road, London SW3 6JJ, UK
    Eur J Surg Oncol 30:686-91. 2004
  7. doi request reprint Melanoma recurrence confined to a free flap after isolated limb perfusion
    C E S Roberts
    The Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK
    J Plast Reconstr Aesthet Surg 62:e277-9. 2009
  8. ncbi request reprint Management of in-transit metastases from cutaneous malignant melanoma
    A J Hayes
    Sarcoma and Melanoma Unit, Department of Surgery, Royal Marsden Hospital, London, UK
    Br J Surg 91:673-82. 2004
  9. doi request reprint Surgical management of primary retroperitoneal sarcoma
    D C Strauss
    Melanoma Sarcoma Unit, Department of Surgery, Royal Marsden Hospital NHS Foundation Trust, London, UK
    Br J Surg 97:698-706. 2010
  10. ncbi request reprint Epithelioid sarcoma: the clinicopathological complexities of this rare soft tissue sarcoma
    A J Spillane
    Sarcoma Unit, Royal Marsden Hospital, London, England, UK
    Ann Surg Oncol 7:218-25. 2000

Collaborators

Detail Information

Publications48

  1. ncbi request reprint Dr. Herbert Lumley Snow, MD, MRCS (1847-1930): the original champion of elective lymph node dissection in melanoma
    Susan J Neuhaus
    FRCP, Sarcoma and Melanoma Unit, The Royal Marsden Hospital, Fulham Road, London, SW3 6JJ, UK
    Ann Surg Oncol 11:875-8. 2004
    ..This article describes the work of Snow within a wider historical context...
  2. ncbi request reprint Retroperitoneal sarcoma
    J M Thomas
    Royal Marsden Hospital, Fulham Road, London, UK
    Br J Surg 94:1057-8. 2007
  3. ncbi request reprint Prognostic false-positivity of the sentinel node in melanoma
    J Meirion Thomas
    Royal Marsden Hospital and Imperial College, London, UK
    Nat Clin Pract Oncol 5:18-23. 2008
    ..Such patients are incorrectly up-staged, are given inaccurate prognostic information and can undergo unnecessary completion lymphadenectomy and unnecessary adjuvant therapy...
  4. ncbi request reprint Caution with sentinel node biopsy in cutaneous melanoma
    J M Thomas
    Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK
    Br J Surg 93:129-30. 2006
  5. doi request reprint Concerns relating to the conduct and statistical analysis of the Multicenter Selective Lymphadenectomy Trial (MSLT-1) in patients with melanoma
    Joseph Meirion Thomas
    Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK
    J Plast Reconstr Aesthet Surg 62:442-6. 2009
    ..In turn that suggests that removing minimally involved sentinel nodes in a proportion of patients offers no therapeutic benefit...
  6. ncbi request reprint Selective lymphadenectomy in sentinel node-positive patients may increase the risk of local/in-transit recurrence in malignant melanoma
    J M Thomas
    Melanoma and Sarcoma Unit, Department of Surgery, The Royal Marsden Hospital, 203 Fulham Road, London SW3 6JJ, UK
    Eur J Surg Oncol 30:686-91. 2004
    ..To determine whether sentinel lymph node biopsy (SLNB) for cutaneous malignant melanoma, particularly when followed by selective lymphadenectomy (SL) if involved nodes are found, alters the incidence of local/in-transit recurrence...
  7. doi request reprint Melanoma recurrence confined to a free flap after isolated limb perfusion
    C E S Roberts
    The Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK
    J Plast Reconstr Aesthet Surg 62:e277-9. 2009
    ..The case highlights interesting questions about the mechanism of action of ILP--especially with regard to free flap tissue--and unknowns regarding tumour spread across wound scar boundaries...
  8. ncbi request reprint Management of in-transit metastases from cutaneous malignant melanoma
    A J Hayes
    Sarcoma and Melanoma Unit, Department of Surgery, Royal Marsden Hospital, London, UK
    Br J Surg 91:673-82. 2004
    ..This article reviews the pathology, clinical significance and treatment options for in-transit disease from melanoma...
  9. doi request reprint Surgical management of primary retroperitoneal sarcoma
    D C Strauss
    Melanoma Sarcoma Unit, Department of Surgery, Royal Marsden Hospital NHS Foundation Trust, London, UK
    Br J Surg 97:698-706. 2010
    ..Local recurrence after surgical resection is the main cause of disease-related mortality in patients with primary retroperitoneal sarcoma (RPS). This study analysed predictors of local recurrence and disease-specific survival...
  10. ncbi request reprint Epithelioid sarcoma: the clinicopathological complexities of this rare soft tissue sarcoma
    A J Spillane
    Sarcoma Unit, Royal Marsden Hospital, London, England, UK
    Ann Surg Oncol 7:218-25. 2000
    ....
  11. doi request reprint The surgical management of soft tissue tumours arising in the abdominal wall
    T Pencavel
    Sarcoma Melanoma Unit, Department of Surgery, Royal Marsden Hospital NHS Foundation Trust, Fulham Road, London SW3 6JJ, UK
    Eur J Surg Oncol 36:489-95. 2010
    ..Soft-tissue tumours can occur at almost any site, including the abdominal wall and represent a biologically diverse group of benign and malignant tumours...
  12. ncbi request reprint Incidence, mortality and survival in cutaneous melanoma
    A V Giblin
    Melanoma and Sarcoma Surgical Unit, Royal Marsden Hospital, 203 Fulham Road, London SW3 6JJ, UK
    J Plast Reconstr Aesthet Surg 60:32-40. 2007
    ..It is likely that any fall in mortality rates from melanoma in the near future will be secondary to early detection. Changes resulting from primary prevention are unlikely to be noticeable for several decades...
  13. ncbi request reprint Prognostic index for extremity soft tissue sarcomas with isolated local recurrence
    R C Ramanathan
    Royal Marsden Hospital, London, United Kingdom
    Ann Surg Oncol 8:278-89. 2001
    ..There is a need for a staging system to predict outcome in this subset of patients and also to plan optimal treatment, including adjuvant systemic therapy...
  14. ncbi request reprint Soft-tissue tumours of the perineum
    K A Behranwala
    Sarcoma and Melanoma Unit, Royal Marsden NHS Trust, London, UK
    Eur J Surg Oncol 28:437-42. 2002
    ..We present our experience of perineal tumours better to characterize and define the natural history of this condition...
  15. ncbi request reprint Surgical management of primary and recurrent retroperitoneal liposarcoma
    S J Neuhaus
    Melanoma Sarcoma Unit, The Royal Marsden Hospital NHS Trust, Fulham Road, London SW3 6JJ, UK
    Br J Surg 92:246-52. 2005
    ..Surgery plays a dominant role in the initial and subsequent treatment of retroperitoneal liposarcoma (RPLS). This study was a review of outcomes of patients treated at the Royal Marsden Hospital...
  16. ncbi request reprint Clear cell sarcoma (melanoma of soft parts): The Royal Marsden Hospital experience
    M A Clark
    Sarcoma and Melanoma Unit, Royal Marsden Hospital, Fulham Road, London SW36JJ, UK
    Eur J Surg Oncol 34:800-4. 2008
    ..Clear cell sarcoma (CCS) is a rare tumour with a propensity for local recurrence and nodal metastasis. About 300 cases have been reported, thus further clarification regarding the course and outcome of the disease is required...
  17. doi request reprint Clinical outcomes of extra-thoracic solitary fibrous tumours
    I M Cranshaw
    Sarcoma and Melanoma Unit, Royal Marsden Hospital, London SW3 6JJ, UK
    Eur J Surg Oncol 35:994-8. 2009
    ..We examined our experience with these rare tumours in an effort to clarify their clinico-pathological behaviour and relate this to their histopathological findings...
  18. doi request reprint The role of core needle biopsy in the diagnosis of suspected soft tissue tumours
    D C Strauss
    Sarcoma Unit, Department of Surgery, Royal Marsden Hospital NHS Foundation Trust, Fulham Road, London, UK
    J Surg Oncol 102:523-9. 2010
    ..The objective of this study was to evaluate the diagnostic accuracy of core needle biopsy (CNB) in patients referred with the suspicion of a soft tissue sarcoma...
  19. doi request reprint Treatment and outcome of radiation-induced soft-tissue sarcomas at a specialist institution
    S J Neuhaus
    Sarcoma and Melanoma Unit, Department of Academic Surgery, Royal Marsden Hospital, Chelsea, London, UK
    Eur J Surg Oncol 35:654-9. 2009
    ..Radiation-induced sarcoma (RIS) is a rare late complication of therapeutic irradiation with a reputation for aggressive pathology and poor outcome...
  20. ncbi request reprint Imaging features of retroperitoneal and pelvic schwannomas
    M J Hughes
    Department of Diagnostic Imaging, Royal Marsden Hospital, London, UK
    Clin Radiol 60:886-93. 2005
    ..To describe the imaging features of retroperitoneal and pelvic schwannomas...
  21. ncbi request reprint Delay in referral to a specialist soft-tissue sarcoma unit
    M A Clark
    Department of Surgery, Melanoma and Sarcoma Unit, The Royal Marsden Hospital, 203 Fulham Road, Chelsea, London SW3 6JJ, UK
    Eur J Surg Oncol 31:443-8. 2005
    ..There are no specific symptoms and signs and the disease can mimic more common benign and malignant conditions. It is not surprising, therefore, that diagnosis and referral to a specialist unit is often delayed...
  22. ncbi request reprint Accuracy of biopsy techniques for limb and limb girdle soft tissue tumors
    I Hoeber
    Sarcoma Unit, Royal Marsden Hospital, London, UK
    Ann Surg Oncol 8:80-7. 2001
    ..The failure to use Tru-cut biopsy is most likely because of the possibility that STS is not suspected in patients with small tumors even when they are deep to the investing fascia...
  23. ncbi request reprint Major amputation for soft-tissue sarcoma
    M A Clark
    Melanoma and Sarcoma Unit, Royal Marsden Hospital, Fulham Road, Chelsea, London SW3 6JJ, UK
    Br J Surg 90:102-7. 2003
    ..Advances in oncological practice have reduced the number of major amputations performed for soft-tissue sarcoma, but this remains a valuable, if infrequent, option for both curative and palliative indications...
  24. ncbi request reprint Surgical management of soft tissue sarcoma in patients over 80 years
    R A Boden
    Sarcoma and Melanoma Unit, Department of Academic Surgery, Royal Marsden Hospital, London SW3 6JJ, UK
    Eur J Surg Oncol 32:1154-8. 2006
    ..To report outcome on patients over 80years of age with soft tissue sarcoma (STS), with respect to surgical treatment, co-morbidity, complications and survival...
  25. ncbi request reprint Serum vascular endothelial growth factor as a tumour marker in soft tissue sarcoma
    A J Hayes
    Sarcoma and Melanoma Unit, Department of Surgery, Royal Marsden Hospital, London, UK
    Br J Surg 91:242-7. 2004
    ..In this study serum levels of VEGF were measured before treatment and during follow-up in patients undergoing primary treatment for suspected soft tissue sarcoma (STS) to assess the value of serum VEGF as a tumour marker...
  26. ncbi request reprint Vulvar soft tissue tumors
    K A Behranwala
    Sarcoma and Gynecology Unit, Royal Marsden NHS Trust, London, UK
    Int J Gynecol Cancer 14:94-9. 2004
    ..To report our incidence of soft tissue tumors at this site and to discuss various prognostic factors...
  27. ncbi request reprint Sentinel lymph node biopsy as the standard of care for cutaneous melanoma
    Vernon K Sondak
    H Lee Moffitt Cancer Center and Research Institute, University of South Florida College of Medicine, Tampa, FL 33612, USA
    Clin Adv Hematol Oncol 5:483-90. 2007
  28. ncbi request reprint Sentinel-node biopsy in melanoma
    J Meirion Thomas
    N Engl J Med 356:418; author reply 419-21. 2007
  29. ncbi request reprint Portsite recurrence after laparoscopy for staging of retroperitoneal sarcoma
    Matthew A Clark
    Surg Laparosc Endosc Percutan Tech 13:290-1. 2003
    ..Nine months later a laparoscopic portsite recurrence was detected clinically and confirmed histologically at resection. Laparoscopy is an unnecessary and inappropriate investigation in retroperitoneal soft-tissue sarcoma...
  30. doi request reprint Multivariable analysis comparing outcome after sentinel node biopsy or therapeutic lymph node dissection in patients with melanoma (Br J Surg 2007; 94: 1293-1299)
    J Meirion Thomas
    Br J Surg 95:664; author reply 664-5. 2008
  31. pmc Sentinel lymph node biopsy in malignant melanoma
    J Meirion Thomas
    BMJ 336:902-3. 2008
  32. ncbi request reprint Excision margins in high-risk malignant melanoma
    J Meirion Thomas
    Royal Marsden Hospital National Health Service Trust, London, United Kingdom
    N Engl J Med 350:757-66. 2004
    ..Controversy exists concerning the necessary margin of excision for cutaneous melanoma 2 mm or greater in thickness...
  33. pmc Sentinel lymph node biopsy: not yet standard of care for melanoma
    J Meirion Thomas
    BMJ 329:170; author reply 170-1. 2004
  34. ncbi request reprint Isolated limb perfusion with melphalan and tumor necrosis factor alpha for advanced melanoma and soft-tissue sarcoma
    Andrew J Hayes
    Department of Surgery, Sarcoma and Melanoma Unit, The Royal Marsden Hospital, Fulham Road, London, SW3 6JJ, United Kingdom
    Ann Surg Oncol 14:230-8. 2007
    ..The addition of tumor necrosis factor (TNF)-alpha may increase response rates for bulky melanoma and for sarcoma, but the potential for major systemic toxicity has limited its use...
  35. ncbi request reprint Sydney Melanoma Unit patients in breach of multicentre selective lymphadenectomy trial protocol?
    J Meirion Thomas
    ANZ J Surg 76:1038-9; author reply 1039-40. 2006
  36. ncbi request reprint Are there guidance issues relating to sentinel node biopsy for melanoma in the UK?
    J Meirion Thomas
    Br J Plast Surg 57:689-90; author reply 690-1. 2004
  37. pmc Cure of cutaneous melanoma
    J Meirion Thomas
    BMJ 332:987-8. 2006
  38. ncbi request reprint Dermatologists should exert a greater influence over sentinel lymph node biopsy for melanoma in the U.K
    J Meirion Thomas
    Br J Dermatol 152:176-7. 2005
  39. ncbi request reprint The place of sentinel node biopsy in melanoma after the Multicenter Selective Lymphadenectomy Trial
    J Meirion Thomas
    Royal Marsden Hospital, London, UK
    ANZ J Surg 76:98-9. 2006
  40. ncbi request reprint Time for comprehensive reporting of MSLT-I
    J Meirion Thomas
    Lancet Oncol 7:9-11; author reply 11-2. 2006
  41. ncbi request reprint Expectoration of endobronchial sarcoma metastasis
    Matthew A Clark
    ANZ J Surg 74:913-4. 2004
  42. ncbi request reprint Amputation for soft-tissue sarcoma
    Matthew A Clark
    Department of Surgery, Middlemore Hospital, Auckland, New Zealand
    Lancet Oncol 4:335-42. 2003
    ....
  43. ncbi request reprint Soft-tissue sarcomas in adults
    Matthew A Clark
    Sarcoma Unit, the Royal Marsden Hospital National Health Service Foundation Trust, London
    N Engl J Med 353:701-11. 2005
  44. ncbi request reprint Intra-abdominal metastases from soft tissue sarcoma
    Kasim A Behranwala
    Sarcoma and Melanoma Unit, Royal Marsden NHS Trust, United Kingdom
    J Surg Oncol 87:116-20. 2004
    ..To define the clinical features and prognosis of patients with abdominal metastasis from primary soft tissue sarcoma (STS) at other sites...
  45. ncbi request reprint A quality-of-life study in high-risk (thickness > = or 2 mm) cutaneous melanoma patients in a randomized trial of 1-cm versus 3-cm surgical excision margins
    Julia A Newton-Bishop
    Division of Genetic Epidemiology, Cancer Research UK Clinical Center, St James s University Hospital, Beckett Street, Leeds, UK
    J Investig Dermatol Symp Proc 9:152-9. 2004
    ..Patients treated by 3-cm excision were more likely, however, to have a persistent poor view of their scar. Youth and being female were also predictors of poor perception of the scar...
  46. ncbi request reprint Primary malignant tumors of the iliopsoas compartment
    Kasim A Behranwala
    Sarcoma and Melanoma Unit Academic Surgery, Royal Marsden NHS Trust, United Kingdom
    J Surg Oncol 86:78-83. 2004
    ..Primary malignant tumors of the iliopsoas compartment are rare entities that have been infrequently reported. We present our experience of iliopsoas malignancy to better characterize and define the natural history of this condition...
  47. ncbi request reprint Prognosis of lymph node metastasis in soft tissue sarcoma
    Kasim A Behranwala
    Sarcoma and Melanoma Unit, Royal Marsden NHS Trust, 203 Fulham Road, London SW3 6JJ, UK
    Ann Surg Oncol 11:714-9. 2004
    ..We defined the tumor characteristics and prognosis of patients with regional lymph node metastasis (RLNM) from soft tissue sarcoma...
  48. ncbi request reprint A gene expression signature associated with metastatic outcome in human leiomyosarcomas
    Yin Fai Lee
    The Male Urological Cancer Research Centre, Institute of Cancer Research, Surrey, United Kingdom
    Cancer Res 64:7201-4. 2004
    ..001). Our finding may aid the tailoring of therapy for individual sarcoma patients, where the aggressiveness of treatment is affected by the predicted outcome of disease...