Research Topics
| R E TaylorSummaryAffiliation: St James's University Hospital Country: UK Publications
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Detail Information
Publications
Review of radiotherapy dose and volume for intracranial ependymomaRoger E Taylor
Cookridge Hospital, Leeds, United Kingdom
Pediatr Blood Cancer 42:457-60. 2004..There are no randomised trials of RT in EP and evidence for dose and volume relies on retrospective single institution series, usually comprising a heterogeneous mix of relatively small numbers of patients recruited over several decades...- Leukemic infiltration of the orbit: report of three cases and literature reviewC W Taylor
Cookridge Hospital, Leeds, United Kingdom
Pediatr Hematol Oncol 22:415-22. 2005..Visual deterioration was prevented in two. Early diagnosis and treatment are important for preservation of vision... - Proton radiotherapy for paediatric tumours: potential areas for clinical researchR E Taylor
Cookridge Hospital, Leeds LS16 6QB, UK
Clin Oncol (R Coll Radiol) 15:S32-6. 2003..Clinical experience of proton radiotherapy for children remains limited with potential areas for clinical research... - Results of a randomized study of preradiation chemotherapy versus radiotherapy alone for nonmetastatic medulloblastoma: The International Society of Paediatric Oncology/United Kingdom Children's Cancer Study Group PNET-3 StudyRoger E Taylor
Cookridge Hospital, Leeds, West Yorkshire, LS16 6QB, United Kingdom
J Clin Oncol 21:1581-91. 2003..Chemotherapy comprised vincristine 1.5 mg/m2 weekly for 10 weeks and four cycles of etoposide 100 mg/m2 daily for 3 days, and carboplatin 500 mg/m2 daily for 2 days alternating with cyclophosphamide 1.5 g/m2... - Outcome for patients with metastatic (M2-3) medulloblastoma treated with SIOP/UKCCSG PNET-3 chemotherapyRoger E Taylor
Cookridge Hospital, Leeds, West Yorkshire LS16 6QB, UK
Eur J Cancer 41:727-34. 2005..Newer approaches such as more intensive CT and RT need to be explored... - Impact of radiotherapy parameters on outcome in the International Society of Paediatric Oncology/United Kingdom Children's Cancer Study Group PNET-3 study of preradiotherapy chemotherapy for M0-M1 medulloblastomaRoger E Taylor
Cookridge Hospital, Leeds, West Yorkshire, United Kingdom
Int J Radiat Oncol Biol Phys 58:1184-93. 2004..To analyze the impact of radiotherapy (RT) parameters on outcome in a randomized study of pre-RT chemotherapy for M0-M1 medulloblastoma... - United Kingdom Children's Cancer Study Group (UKCCSG) radiotherapy and brain tumour groups: medulloblastoma/PNET and craniospinal radiotherapy (CSRT): report of a workshop held in Leeds, 30 June 1999R E Taylor
Cookridge Hospital, Leeds, UK
Clin Oncol (R Coll Radiol) 13:58-64. 2001..Current results of the treatement of medulloblastoma and PNET were reviewed and UK involvement in possible future collaborative trials was discussed... - Fatal pneumonitis in children with metastatic rhabdomyosarcoma following whole lung radiotherapy and sequential epirubicinR J Prestwich
Department of Clinical Oncology, Cookridge Hospital, Yorkshire Cancer Centre, West Yorkshire, UK
Pediatr Blood Cancer 48:586-90. 2007..These cases highlight a potentially fatal interaction between radiotherapy and modern chemotherapy regimens... - Radiotherapy for medulloblastoma in children: a perspective on current international clinical research effortsCarolyn R Freeman
Department of Oncology, Division of Radiation Oncology, McGill University, Montreal, Canada
Med Pediatr Oncol 39:99-108. 2002..In this article, we will review the results of these studies with respect specifically to the use of radiotherapy, and trace the developments that have led up to the present trials for patients with this tumor... - Current and future strategies in radiotherapy of childhood low-grade glioma of the brain. Part I: Treatment modalities of radiation therapyRolf Dieter Kortmann
Department of Radiooncology, University of Tubingen, Germany
Strahlenther Onkol 179:509-20. 2003..Treatment of childhood low-grade gliomas is a challenging issue owing to their low incidence and the lack of consensus about "optimal" treatment approach... - Morphophenotypic variation predicts clinical behavior in childhood non-desmoplastic medulloblastomasCharles S McManamy
Northern Institute for Cancer Research, University of Newcastle, Newcastle-upon-Tyne, UK
J Neuropathol Exp Neurol 62:627-32. 2003..Our study supports the concept of an anaplastic variant among MBs, demonstrating that it has clinical utility... - beta-Catenin status predicts a favorable outcome in childhood medulloblastoma: the United Kingdom Children's Cancer Study Group Brain Tumour CommitteeDavid W Ellison
Northern Institute for Cancer Research, University of Newcastle, UK
J Clin Oncol 23:7951-7. 2005..We tested the hypothesis that nuclear immunoreactivity for beta-catenin is a prognostic marker in medulloblastoma, and assessed the relationship between nuclear beta-catenin immunoreactivity and mutations of CTNNB1 and APC... - Current developments in radiotherapy for paediatric brain tumoursRoger E Taylor
Clinical Oncology, South West Wales Cancer Institute, Singleton Hospital, Swansea, West Glamorgan, SA2 8QA, UK
Eur J Paediatr Neurol 10:167-75. 2006..The introduction of models to predict the impact of radiotherapy dose-volume parameters on long-term neuropsychological function will hopefully lead to further benefit with respect to sparing of normal tissue morbidity... - Analysis of patients with supratentorial primitive neuro-ectodermal tumours entered into the SIOP/UKCCSG PNET 3 studyBarry L Pizer
Alder Hey s Children s Hospital Oncology Unit, Eaton Road, Liverpool L12 2AP, UK
Eur J Cancer 42:1120-8. 2006..Future treatment programs should be directed at the particular natural history of these tumours, to further define prognostic factors and to explore further biological characteristics... - Quantitative assessment of inter-clinician variability of target volume delineation for medulloblastoma: quality assurance for the SIOP PNET 4 trial protocolCharlotte E Coles
Oncology Centre, Addenbrooke's Hospital, Box 193, Hills Road, Cambridge CB2 2QQ, UK
Radiother Oncol 69:189-94. 2003..In the future, the use of image transfer will allow prospective peer review of target volumes before treatment commences. These measures are essential to ensure that alterations in clinical practice are achieved in a uniform way... - Metastatic myxoid liposarcoma: aggressive multimodality managementRobin J Prestwich
Clin Oncol (R Coll Radiol) 17:130. 2005 - Current and future strategies in radiotherapy of childhood low-grade glioma of the brain. Part II: Treatment-related late toxicityRolf Dieter Kortmann
Department of Radiooncology, University of Tubingen, Germany
Strahlenther Onkol 179:585-97. 2003..As this tumor carries an excellent long-term prognosis, the risk of late effects is of particular clinical importance and impinges upon radiotherapeutic treatment strategies... - Nodule formation and desmoplasia in medulloblastomas-defining the nodular/desmoplastic variant and its biological behaviorCharles S McManamy
Northern Institute for Cancer Research, University of Newcastle, and Department of Neuropathology, Newcastle upon Tyne Hospitals Trust, Newcastle upon Tyne, UK
Brain Pathol 17:151-64. 2007..In conclusion, the nodular/desmoplastic medulloblastoma appears to have clinical, genetic and biological characteristics that set it apart from other variants of this tumor...