Amy Sexton

Summary

Affiliation: St George's
Country: UK

Publications

  1. ncbi Transgenic plant production of Cyanovirin-N, an HIV microbicide
    Amy Sexton
    Centre for Infection, Department of Cellular and Molecular Medicine, St George s University of London, London, UK
    FASEB J 20:356-8. 2006
  2. doi Design, expression, and characterization of a multivalent, combination HIV microbicide
    Amy Sexton
    Department of Cellular and Molecular Medicine, St George s Hospital Medical School, Cranmer Terr, London SW17 0RE, UK
    FASEB J 23:3590-600. 2009
  3. doi Development of rhizosecretion as a production system for recombinant proteins from hydroponic cultivated tobacco
    Pascal M W Drake
    Molecular Immunology Unit, Department of Cellular and Molecular Medicine, St George s Hospital Medical School, University of London, Cranmer Terrace, London SW17 0RE, UK
    FASEB J 23:3581-9. 2009
  4. pmc Characterization of Salmonella enterica derivatives harboring defined aroC and Salmonella pathogenicity island 2 type III secretion system (ssaV) mutations by immunization of healthy volunteers
    Zoe Hindle
    Microscience, Wokingham Berkshire RG41 5TU, United Kingdom
    Infect Immun 70:3457-67. 2002
  5. pmc Protective levels of diphtheria-neutralizing antibody induced in healthy volunteers by unilateral priming-boosting intranasal immunization associated with restricted ipsilateral mucosal secretory immunoglobulin a
    Kingston H G Mills
    Immune Regulation Research Group, Department of Biochemistry, Trinity College, Dublin 2, Ireland
    Infect Immun 71:726-32. 2003

Collaborators

  • Julian K C Ma
  • Robin J Shattock
  • Pascal M W Drake
  • Kingston H G Mills
  • David J M Lewis
  • George E Griffin
  • Zoe Hindle
  • Inderjit Jabbal-Gill
  • Anne Church
  • Catherine Cosgrove
  • Rino Rappuoli
  • Rafaela Giemza
  • Wu Lin
  • Mariagrazia Pizza
  • Audino Podda
  • Edel A McNeela
  • Lisbeth Illum
  • Robert G Feldman
  • Catherine A Cosgrove
  • Jaqueline E Shea
  • Frank R Brennan
  • Deborah House
  • Shahid A Khan
  • Tao Wu
  • Mohammad Khan
  • Jo Phillimore
  • Marjan Ghaem-Maghami
  • Derek Pickard
  • Steven N Chatfield
  • Paul Everest
  • Julie Johnson
  • Matthew Bentley
  • Gordon Dougan
  • Joseph D Santangelo
  • David W Holden

Detail Information

Publications5

  1. ncbi Transgenic plant production of Cyanovirin-N, an HIV microbicide
    Amy Sexton
    Centre for Infection, Department of Cellular and Molecular Medicine, St George s University of London, London, UK
    FASEB J 20:356-8. 2006
    ..64 mug/ml hydroponic media after 24 days. Therefore, we suggest that transgenic plants have the potential to provide strategies for large-scale protein microbicide production...
  2. doi Design, expression, and characterization of a multivalent, combination HIV microbicide
    Amy Sexton
    Department of Cellular and Molecular Medicine, St George s Hospital Medical School, Cranmer Terr, London SW17 0RE, UK
    FASEB J 23:3590-600. 2009
    ..This fusion protein addresses the requirement to combine microbicide products, and the production in plants is a step toward resolving the issues of manufacturing scalability and cost for developing countries...
  3. doi Development of rhizosecretion as a production system for recombinant proteins from hydroponic cultivated tobacco
    Pascal M W Drake
    Molecular Immunology Unit, Department of Cellular and Molecular Medicine, St George s Hospital Medical School, University of London, Cranmer Terrace, London SW17 0RE, UK
    FASEB J 23:3581-9. 2009
    ....
  4. pmc Characterization of Salmonella enterica derivatives harboring defined aroC and Salmonella pathogenicity island 2 type III secretion system (ssaV) mutations by immunization of healthy volunteers
    Zoe Hindle
    Microscience, Wokingham Berkshire RG41 5TU, United Kingdom
    Infect Immun 70:3457-67. 2002
    ..These data indicate that mutations in type III secretion systems may provide a route to the development of live vaccines in humans and highlight significant differences in the potential use of serovars Typhimurium and Typhi...
  5. pmc Protective levels of diphtheria-neutralizing antibody induced in healthy volunteers by unilateral priming-boosting intranasal immunization associated with restricted ipsilateral mucosal secretory immunoglobulin a
    Kingston H G Mills
    Immune Regulation Research Group, Department of Biochemistry, Trinity College, Dublin 2, Ireland
    Infect Immun 71:726-32. 2003
    ..However, a restricted sIgA response suggests that care must be taken in the priming-boosting strategy and clinical sampling techniques when evaluating such vaccines for the induction of local mucosal immunity...