Nathalie Percie du Sert

Summary

Affiliation: St George's
Country: UK

Publications

  1. ncbi The delayed phase of cisplatin-induced emesis is mediated by the area postrema and not the abdominal visceral innervation in the ferret
    Nathalie Percie du Sert
    Division of Basic Medical Sciences, St George s University of London, Cranmer Terrace, London, SW17 0RE, UK
    Neurosci Lett 465:16-20. 2009
  2. ncbi Reduced normogastric electrical activity associated with emesis: a telemetric study in ferrets
    Nathalie Percie du Sert
    Division of Basic Medical Sciences, St George s University of London, Cranmer Terrace, SW17 0RE, London, United Kingdom
    World J Gastroenterol 15:6034-43. 2009
  3. ncbi Telemetry in a motion-sickness model implicates the abdominal vagus in motion-induced gastric dysrhythmia
    Nathalie Percie du Sert
    University of London, UK
    Exp Physiol 95:768-73. 2010
  4. ncbi Cisplatin-induced emesis: systematic review and meta-analysis of the ferret model and the effects of 5-HT₃ receptor antagonists
    N Percie du Sert
    Division of Basic Medical Sciences, St George s University of London, London, UK
    Cancer Chemother Pharmacol 67:667-86. 2011
  5. ncbi Cannabinoid-induced reduction in antral pacemaker frequency: a telemetric study in the ferret
    N Percie du Sert
    Division of Basic Medical Sciences, St George s University of London, London, UK
    Neurogastroenterol Motil 22:1257-66, e324. 2010
  6. ncbi Predicting the emetic liability of novel chemical entities: a comparative study
    Nathalie Percie du Sert
    The National Centre for the Replacement, Refinement and Reduction of Animals in Research, London, UK
    Br J Pharmacol 165:1848-67. 2012

Detail Information

Publications6

  1. ncbi The delayed phase of cisplatin-induced emesis is mediated by the area postrema and not the abdominal visceral innervation in the ferret
    Nathalie Percie du Sert
    Division of Basic Medical Sciences, St George s University of London, Cranmer Terrace, London, SW17 0RE, UK
    Neurosci Lett 465:16-20. 2009
    ..6R+V (p=0.009) were observed in APX animals. These data suggest that, in contrast to the acute emetic response triggered by cisplatin, the delayed phase does not rely on abdominal visceral afferents but is mediated via the area postrema...
  2. ncbi Reduced normogastric electrical activity associated with emesis: a telemetric study in ferrets
    Nathalie Percie du Sert
    Division of Basic Medical Sciences, St George s University of London, Cranmer Terrace, SW17 0RE, London, United Kingdom
    World J Gastroenterol 15:6034-43. 2009
    ..To characterize the gastric myoelectric activity (GMA) and intra-abdominal pressure changes induced by emetic stimuli (apomorphine and cisplatin) in the ferret...
  3. ncbi Telemetry in a motion-sickness model implicates the abdominal vagus in motion-induced gastric dysrhythmia
    Nathalie Percie du Sert
    University of London, UK
    Exp Physiol 95:768-73. 2010
    ..In conclusion, motion had a differential effect in sham-operated and vagotomized animals, which is consistent with the hypothesis that motion-induced dysrhythmia arises from an autonomic nervous system imbalance...
  4. ncbi Cisplatin-induced emesis: systematic review and meta-analysis of the ferret model and the effects of 5-HT₃ receptor antagonists
    N Percie du Sert
    Division of Basic Medical Sciences, St George s University of London, London, UK
    Cancer Chemother Pharmacol 67:667-86. 2011
    ..We provide an objective assessment of this model including efficacy of 5-HT₃ receptor antagonists to assess its translational validity...
  5. ncbi Cannabinoid-induced reduction in antral pacemaker frequency: a telemetric study in the ferret
    N Percie du Sert
    Division of Basic Medical Sciences, St George s University of London, London, UK
    Neurogastroenterol Motil 22:1257-66, e324. 2010
    ..Cannabinoids have broad-spectrum antiemetic and antinauseant activity. Paradoxically, they inhibit intestinal peristalsis and reduce gastric motility but their effect on GMA remains unknown...
  6. ncbi Predicting the emetic liability of novel chemical entities: a comparative study
    Nathalie Percie du Sert
    The National Centre for the Replacement, Refinement and Reduction of Animals in Research, London, UK
    Br J Pharmacol 165:1848-67. 2012
    ..The aim of the study is to compare the response induced by emetic compounds across species and investigate whether dogs, ferrets and rats are all similarly predictive of humans...