Research Topics
| Paul JonesSummaryAffiliation: St George's Hospital Medical School Country: UK Publications
| Collaborators
|
Detail Information
Publications
Health status measurement in chronic obstructive pulmonary diseaseP W Jones
Department of Respiratory Medicine, Division of Physiological Medicine, St George s Hospital Medical School, London SW17 0RE, UK
Thorax 56:880-7. 2001..Finally, it addresses the question of how symptomatic benefit may be assessed in individual patients in routine practice...
Clinical effects of inhaled corticosteroids in chronic obstructive pulmonary diseasePaul W Jones
Respiratory Medicine, St George s Hospital Medical School, London SW 17 0RE, UK
Proc Am Thorac Soc 1:167-70. 2004..The effect of fluticasone on health appears to be due to a reduction in exacerbations coupled with its small effect on FEV(1)...- St. George's Respiratory Questionnaire: MCIDPaul W Jones
St George s Hospital Medical School, London, UK
COPD 2:75-9. 2005.... - Activity limitation and quality of life in COPDPaul W Jones
St George s, University of London, London, United Kingdom
COPD 4:273-8. 2007..This suggests that self-reported limitation of activity may form a reliable construct, and may also provide a good surrogate marker of health status in COPD... 
Patient-centred assessment of COPD in primary care: experience from a cross-sectional study of health-related quality of life in EuropePaul W Jones
Division of Clinical Science, St George s, University of London, London, UK
Prim Care Respir J 21:329-36. 2012..Most patients with chronic obstructive pulmonary disease (COPD) in Europe are treated in primary care, but perceptions on what guides primary care physicians (PCPs) in managing patients are lacking...- COPD uncovered: an international survey on the impact of chronic obstructive pulmonary disease [COPD] on a working age populationMonica J Fletcher
Education for Health, Warwick, UK
BMC Public Health 11:612. 2011..The burden of disease is known to be high, though less is known about those of a younger age. The aim of this study was to investigate the wider personal, economic and societal burden of COPD on a cross country working-age cohort... - Properties of the COPD assessment test in a cross-sectional European studyP W Jones
Division of Clinical Science, St George s University of London, Cranmer Terrace, London SW17 0RE, UK
Eur Respir J 38:29-35. 2011..8, p<0.0001). The CAT is a simple and easy-to-use questionnaire that distinguishes between patients of different degrees of COPD severity and appears to behave the same way across countries... - Health-related quality of life in patients by COPD severity within primary care in EuropeP W Jones
Division of Clinical Science, St George s University of London, London, UK
Respir Med 105:57-66. 2011..Within each GOLD stage of severity there is considerable heterogeneity in HRQL impairment among patients. (Study number: 111749)... - Measuring the effects of COPD on the patientPaul Jones
St George s Hospital Medical School, Cranmer Terrace, London SW17 0RE, UK
Respir Med 99:S11-8. 2005..Future developments will include computerising these methodologies to permit faster and more individual patient-centred measurements... - Applying evidence and theory to guide clinical decision making--implications for asthma managementP W Jones
St George s Hospital Medical School, Cranmer Terrace, London SW17 0RE, U K
Respir Med 96:567-71. 2002..However, this process can be facilitated by physician education and participation in intervention programmes. In addition, it is important that clinicians are trained in how to convey the best possible evidence to their asthma patients... - Cost-effectiveness of salmeterol in patients with chronic obstructive pulmonary disease: an economic evaluationP W Jones
Division of Physiological Medicine, St George s Hospital Medical School, London, UK
Respir Med 97:20-6. 2003..Addition of salmeterol to COPD patients' current therapy improved lung function, health status at the expense of a modest increase in costs compared with usual therapy... - An introduction to systematic reviews in respiratory medicineP W Jones
Division of Physiological Medicine, St George s Hospital Medical School, London, UK
Respir Med 97:97-103. 2003.... - Methodological issues in evaluating measures of health as outcomes for COPDP W Jones
St George s Hospital Medical School, London, UK
Eur Respir J Suppl 41:13s-18s. 2003..Utility-based measures help address concerns regarding clinical versus statistical improvement and place outcomes for chronic obstructive pulmonary disease treatment trials in the context of all healthcare treatments... - Disease severity and the effect of fluticasone propionate on chronic obstructive pulmonary disease exacerbationsP W Jones
Division of Physiological Medicine, St George s Hospital Medical School, London, UK
Eur Respir J 21:68-73. 2003.... - Interpreting thresholds for a clinically significant change in health status in asthma and COPDP W Jones
St George s Hospital Medical School, London, UK
Eur Respir J 19:398-404. 2002..Finally, an attempt is made to translate these thresholds into scenarios that illustrate what a clinically significant change with treatment may mean to an individual patient... - Beyond FEV₁ in COPD: a review of patient-reported outcomes and their measurementPaul Jones
Division of Clinical Science, University of London, London, UK
Int J Chron Obstruct Pulmon Dis 7:697-709. 2012..In turn, this will help us to understand better the patient's experience of the disease... - Retrospective cohort study of false alarm rates associated with a series of heart operations: the case for hospital mortality monitoring groupsJan Poloniecki
Community Health Sciences, St George s Hospital Medical School, London SW17 0RE
BMJ 328:375. 2004..To examine the efficacy of different methods of detecting a high death rate and determining whether an increase in deaths after heart transplantation could be explained by chance... - Improving the process and outcome of care in COPD: development of a standardised assessment toolPaul Jones
Department of Cardiac and Vascular Sciences, St George s Hospital, University of London, London, UK
Prim Care Respir J 18:208-15. 2009..This goal requires regular systematic assessment of the patient's COPD with clear and efficient communication between the patient and clinician... - Predicting EQ-5D values using the SGRQHelen J Starkie
National Institute for Health and Clinical Excellence, London, UK
Value Health 14:354-60. 2011..George's Respiratory Questionnaire (SGRQ) in subjects with chronic obstructive pulmonary disease and to examine the effect of using this algorithm in predicting quality-adjusted life-years (QALYs)... - Utility estimation in chronic obstructive pulmonary disease: a preference for change?Jennifer Petrillo
Department of Health Services Research and Policy, London School of Hygiene and Tropical Medicine, London, UK
Pharmacoeconomics 29:917-32. 2011..The trade-off allows relevant and sensitive matters most important to patients to be evaluated; however inevitable gaps such as those related to adverse events are not considered... - Development and Validation of an Improved, COPD-Specific Version of the St. George Respiratory QuestionnaireMakiko Meguro
Cardiac and Vascular Sciences, St George s, University of London, Cranmer Terrace, London, UK
Chest 132:456-63. 2007..To produce an improved, COPD-specific version of the St. George respiratory questionnaire (SGRQ-C)... - Health status and the spiral of declinePaul W Jones
St George s, University of London, Cranmer Terrace, London, UK
COPD 6:59-63. 2009..Inhaled corticosteroids have been shown to reduce the rate of decline of health status, possibly due to exacerbation prevention... - Quantifying of severity of exacerbations in chronic obstructive pulmonary disease: adaptations to the definition to allow quantificationPaul Jones
St George s, University of London, Cranmer Terrace, London, SW17 0RE, UK
Proc Am Thorac Soc 4:597-601. 2007..Methods for defining exacerbation onset and cessation are also proposed... - The effect of helium and oxygen on exercise performance in chronic obstructive pulmonary disease: a randomized crossover trialElizabeth A Laude
Respiratory Medicine, Royal Hallamshire Hospital, Department of General Practice and Primary Care, ScHARR, Biomedical Sciences, University of Sheffield, Sheffield, UK
Am J Respir Crit Care Med 173:865-70. 2006..Replacing nitrogen with helium reduces expiratory flow resistance and may improve lung emptying. Combining these treatments should be independently effective... - Corticosteroid therapy in pulmonary sarcoidosis: a systematic reviewShanthi Paramothayan
Division of Physiological Medicine, St George's Hospital Medical School, Cranmer Terrace, London SW17 ORE, England
JAMA 287:1301-7. 2002..Trials of inhaled corticosteroids were small and results too inconsistent to make firm conclusions concerning their efficacy. There are no data to suggest that corticosteroid therapy alters long-term disease progression... - Adapting to asthma: are some asthma effects acceptable?Elizabeth A Barley
Department of Medicine, Respiratory Medicine, Cardiac and Vascular Sciences, St George s, University of London, London, United Kingdom
J Asthma 43:433-8. 2006..We conclude that patients accept some asthma effects but do not appear to discount them when using a detailed health status questionnaire... - Repeatability of a Rasch model of the AQ20 over five assessmentsElizabeth A Barley
Division of Physiological Medicine, Department of Medicine, St George s, University of London, Cranmer Terrace, SW17 0RE, London, UK
Qual Life Res 15:801-9. 2006..This is important as inclusion of 'time-dependent' items in a questionnaire may reduce the reliability of the instrument... - Symptom measurementPaul W Jones
Chest 134:226-7. 2008 - It's about time--directing our attention toward modifying the course of COPDMario Cazzola
University of Rome Tor Vergata, Department of Internal Medicine, Unit of Respiratory Diseases, Rome, Italy
Respir Med 102:S37-48. 2008..In this review we have considered three approaches toward modifying the course of COPD: smoking cessation, reduction in lung hyperinflation through medical and surgical approaches, and long-term pharmacotherapy... - Effect of pharmacotherapy on rate of decline of lung function in chronic obstructive pulmonary disease: results from the TORCH studyBartolome R Celli
Tufts University School of Medicine, Pulmonary and Critical Care Division, Caritas St Elizabeth s Medical Center, Boston, MA 02135 2997, USA
Am J Respir Crit Care Med 178:332-8. 2008..Chronic obstructive pulmonary disease (COPD) is characterized by an accelerated decline in lung function. No drug has been shown conclusively to reduce this decline... - Brazilian version of airways questionnaire 20: a reproducibility study and correlations in patients with COPDAquiles Camelier
Pulmonary Division, Rehabilitation Center, Federal University of Sao Paulo, SP, Brazil
Respir Med 99:602-8. 2005..It can be concluded that AQ20 is reproducible, with an excellent correlation with SGRQ total score, and also having the advantage of taking just a few minutes to be applied and to have its score calculated... - Health status: what does it mean for payers and patients?Paul W Jones
St George s, University of London, UK
Proc Am Thorac Soc 3:222-6. 2006..Improved health does not improve mortality or morbidity per se. It is also important to appreciate that the impact of any measured change in health may also be determined by the patient's baseline state... - Evaluation of male COPD patients' health status by proxiesCarme Santiveri
Respiratory Department, Dos de Maig Hospital, Consorci Sanitari Integral, Barcelona 08025, Catalonia, Spain
Respir Med 101:439-45. 2007..The aim of this study was to analyse the reliability and validity of the St. George's Respiratory Questionnaire (SGRQ) answered by proxies and to determine their accuracy as raters... - Salmeterol and fluticasone propionate and survival in chronic obstructive pulmonary diseasePeter M A Calverley
University Hospital Aintree, Liverpool, United Kingdom
N Engl J Med 356:775-89. 2007..Long-acting beta-agonists and inhaled corticosteroids are used to treat chronic obstructive pulmonary disease (COPD), but their effect on survival is unknown... - Withdrawal from treatment as an outcome in the ISOLDE study of COPDPeter M A Calverley
Department of Medicine, University Hospital Aintree, Liverpool, United Kingdom
Chest 124:1350-6. 2003..To investigate the determinants of patient withdrawal from our study, and the effect of these withdrawals on the outcome of treatment with inhaled corticosteroids in patients with COPD... - The severity of airways obstruction as a determinant of treatment response in COPDPeter Calverley
Clinical Research Centre, University Hospital Aintree, Liverpool, UK
Int J Chron Obstruct Pulmon Dis 1:209-18. 2006.... - Health-related quality of life in patients with chronic respiratory failure after long-term mechanical ventilationSara Euteneuer
Krankenhaus Kloster Grafschaft, Schmallenberg, Germany
Respir Med 100:477-86. 2006..Despite severe physical handicaps due to CRF mental health is only mildly compromised... - Measuring functional performance in patients with COPD: a discussion of patient-reported outcome measuresDonald E Stull
Center for Health Outcomes Research, United BioSource Corporation, Bethesda, MD, USA
Curr Med Res Opin 23:2655-65. 2007....