Steven Conway

Summary

Affiliation: St James's University Hospital
Country: UK

Publications

  1. doi request reprint Bloodstream infections in cystic fibrosis: nine years of experience in both adults and children
    James Cargill
    Department of Microbiology, Leeds Teaching Hospitals NHS Trust, Leeds, UK
    J Cyst Fibros 11:337-9. 2012
  2. doi request reprint Enteral tube feeding for cystic fibrosis
    Steven Conway
    Regional Adult Cystic Fibrosis Unit, St James Hospital, Leeds, UK
    Cochrane Database Syst Rev 12:CD001198. 2012
  3. ncbi request reprint Antibiotic treatment of multidrug-resistant organisms in cystic fibrosis
    S P Conway
    Paediatric and Adult Regional Cystic Fibrosis Centres, St James and Seacroft University Hospitals, Leeds, UK
    Am J Respir Med 2:321-32. 2003
  4. ncbi request reprint Vitamin K status among children with cystic fibrosis and its relationship to bone mineral density and bone turnover
    Steven P Conway
    Pediatric Cystic Fibrosis Unit, St James University Hospital, Leeds, United Kingdom
    Pediatrics 115:1325-31. 2005
  5. pmc Effect of oral bisphosphonates on bone mineral density and body composition in adult patients with cystic fibrosis: a pilot study
    S P Conway
    Regional Cystic Fibrosis Unit, Seacroft Hospital, Leeds LS14 6UH, UK
    Thorax 59:699-703. 2004
  6. pmc Vitamin K in cystic fibrosis
    S P Conway
    St James s University Hospital, Beckett Street, Leeds LS9 7TF, UK
    J R Soc Med 97:48-51. 2004
  7. ncbi request reprint Pharmacokinetics and safety of itraconazole in patients with cystic fibrosis
    Steven P Conway
    The Paediatric and Adult Cystic Fibrosis Units and Department of Pharmacy, St James and Seacroft Hospitals, Leeds, UK
    J Antimicrob Chemother 53:841-7. 2004
  8. doi request reprint A cross-sectional study of bone mineral density in children and adolescents attending a Cystic Fibrosis Centre
    Steven P Conway
    Regional Paediatric Cystic Fibrosis Centre, St James s Hospital, Leeds Teaching Hospitals Trust, Beckett Street, Leeds, LS9 7TF, UK
    J Cyst Fibros 7:469-76. 2008
  9. pmc Segregation is good for patients with cystic fibrosis
    Steven Conway
    Regional Paediatric and Adult Cystic Fibrosis Centres, Childrens Day Hospital, St James University Hospital Beckett Street, Leeds LS9 7TF, UK
    J R Soc Med 101:S31-5. 2008
  10. ncbi request reprint Prevention of chronic Pseudomonas aeruginosa infection in people with cystic fibrosis
    Steven P Conway
    CF Services, Leeds Regional Paediatric Cystic Fibrosis Centre, Childrens Day Hospital, St James s University Hospital, Beckett Street, Leeds LS9 7TF, UK
    Expert Rev Respir Med 3:349-61. 2009

Collaborators

Detail Information

Publications50

  1. doi request reprint Bloodstream infections in cystic fibrosis: nine years of experience in both adults and children
    James Cargill
    Department of Microbiology, Leeds Teaching Hospitals NHS Trust, Leeds, UK
    J Cyst Fibros 11:337-9. 2012
    ..We report the aetiology and outcome of bloodstream infections (BSI) occurring at two regional cystic fibrosis (CF) centres (one adult, one paediatric) between 1998 and 2006...
  2. doi request reprint Enteral tube feeding for cystic fibrosis
    Steven Conway
    Regional Adult Cystic Fibrosis Unit, St James Hospital, Leeds, UK
    Cochrane Database Syst Rev 12:CD001198. 2012
    ..The use of this method of feeding is assessed on an individual basis taking into consideration the patients age and clinical status...
  3. ncbi request reprint Antibiotic treatment of multidrug-resistant organisms in cystic fibrosis
    S P Conway
    Paediatric and Adult Regional Cystic Fibrosis Centres, St James and Seacroft University Hospitals, Leeds, UK
    Am J Respir Med 2:321-32. 2003
    ....
  4. ncbi request reprint Vitamin K status among children with cystic fibrosis and its relationship to bone mineral density and bone turnover
    Steven P Conway
    Pediatric Cystic Fibrosis Unit, St James University Hospital, Leeds, United Kingdom
    Pediatrics 115:1325-31. 2005
    ..The aim of this study was to assess vitamin K status in an unselected population of children with cystic fibrosis (CF) and to investigate any vitamin K effect on bone turnover and bone mineral status...
  5. pmc Effect of oral bisphosphonates on bone mineral density and body composition in adult patients with cystic fibrosis: a pilot study
    S P Conway
    Regional Cystic Fibrosis Unit, Seacroft Hospital, Leeds LS14 6UH, UK
    Thorax 59:699-703. 2004
    ..Vertebral collapse and rib fractures will impair the ability to cough and the efficacy of physiotherapy treatments...
  6. pmc Vitamin K in cystic fibrosis
    S P Conway
    St James s University Hospital, Beckett Street, Leeds LS9 7TF, UK
    J R Soc Med 97:48-51. 2004
  7. ncbi request reprint Pharmacokinetics and safety of itraconazole in patients with cystic fibrosis
    Steven P Conway
    The Paediatric and Adult Cystic Fibrosis Units and Department of Pharmacy, St James and Seacroft Hospitals, Leeds, UK
    J Antimicrob Chemother 53:841-7. 2004
    ..To assess the pharmacokinetics of itraconazole and hydroxy-itraconazole in patients with cystic fibrosis...
  8. doi request reprint A cross-sectional study of bone mineral density in children and adolescents attending a Cystic Fibrosis Centre
    Steven P Conway
    Regional Paediatric Cystic Fibrosis Centre, St James s Hospital, Leeds Teaching Hospitals Trust, Beckett Street, Leeds, LS9 7TF, UK
    J Cyst Fibros 7:469-76. 2008
    ..Low bone mineral density is common in adults with cystic fibrosis. Children with good lung function compared to controls matched for body size have normal bone mineralisation. There are few data in large unselected populations of children...
  9. pmc Segregation is good for patients with cystic fibrosis
    Steven Conway
    Regional Paediatric and Adult Cystic Fibrosis Centres, Childrens Day Hospital, St James University Hospital Beckett Street, Leeds LS9 7TF, UK
    J R Soc Med 101:S31-5. 2008
  10. ncbi request reprint Prevention of chronic Pseudomonas aeruginosa infection in people with cystic fibrosis
    Steven P Conway
    CF Services, Leeds Regional Paediatric Cystic Fibrosis Centre, Childrens Day Hospital, St James s University Hospital, Beckett Street, Leeds LS9 7TF, UK
    Expert Rev Respir Med 3:349-61. 2009
    ..Clinicians should adopt a proactive protocol to prevent chronic infection. The cornerstones of such a policy are microbiological surveillance, infection control and antibiotic-based eradication regimens...
  11. ncbi request reprint Clinical impact of reducing routine susceptibility testing in chronic Pseudomonas aeruginosa infections in cystic fibrosis
    Christine Etherington
    Adult Cystic Fibrosis Unit, Seacroft Hospital, Leeds LS14 6UH, UK
    J Antimicrob Chemother 61:425-7. 2008
    ..aeruginosa infection can be carried out without impacting on short-term clinical outcomes...
  12. pmc Isolation of the fungus Geosmithia argillacea in sputum of people with cystic fibrosis
    R C Barton
    Mycology Reference Centre, Leeds General Infirmary, Leeds, United Kingdom
    J Clin Microbiol 48:2615-7. 2010
    ..Identification was based on morphology and DNA sequence analysis. Isolation of G. argillacea did not appear to be associated with clinical deterioration. The pathogenic potential of G. argillacea is discussed...
  13. doi request reprint Serologic diagnosis of allergic bronchopulmonary aspergillosis in patients with cystic fibrosis through the detection of immunoglobulin G to Aspergillus fumigatus
    Richard C Barton
    Department of Microbiology, Leeds Teaching Hospitals Trust, Leeds, UK
    Diagn Microbiol Infect Dis 62:287-91. 2008
    ..This quantitative approach to Aspergillus IgG measurement in patients with CF along with the results of other tests will hopefully provide a more accurate approach to the diagnosis of ABPA...
  14. pmc Osteoporosis and osteopenia in adults and adolescents with cystic fibrosis: prevalence and associated factors
    S P Conway
    Adult Cystic Fibrosis Unit, Seacroft Hospital, Leeds LS14 6UH, UK
    Thorax 55:798-804. 2000
    ..The aim of this study was to determine the prevalence of osteoporosis and osteopenia in a large cross section of patients and to identify risk factors...
  15. ncbi request reprint Impact of lung inflammation on bone metabolism in adolescents with cystic fibrosis
    S P Conway
    St James's and Seacroft University Hospitals, Leeds, UK
    Paediatr Respir Rev 2:324-31. 2001
    ..All patients should be scanned at least every 2 years from adolescence. The treatment of established disease with bisphosphonates shows encouraging early results...
  16. doi request reprint Exercise during childhood and adolescence: a prophylaxis against cystic fibrosis-related low bone mineral density? Exercise for bone health in children with cystic fibrosis
    K Hind
    Carnegie Research Institute, Faculty of Sport and Education, Leeds Metropolitan University, Headingley Campus, Leeds, LS6 3QS, UK
    J Cyst Fibros 7:270-6. 2008
    ..As exercise may offer an effective and enjoyable strategy to improve the bone development in children who have CF, exercise should be a high priority for randomised controlled trials in this population...
  17. doi request reprint Serum tobramycin levels following delivery of tobramycin (Tobi) via eFlow advanced nebuliser in children with cystic fibrosis
    E L Guy
    Leeds Regional Paediatric Cystic Fibrosis Centre, St James s University Hospital, Leeds, LS9 7TF, United Kingdom
    J Cyst Fibros 9:292-5. 2010
    ..Safety and toxicity data for nebulised tobramycin are mainly derived from use of the Pari LC Plus nebuliser, yet many centres are now using advanced nebulisers, such as the eFlow...
  18. ncbi request reprint Safety and tolerability of bolus intravenous colistin in acute respiratory exacerbations in adults with cystic fibrosis
    S P Conway
    CF Services, St James s University Hospital, Leeds, England
    Ann Pharmacother 34:1238-42. 2000
    ..To assess the safety and tolerability of bolus intravenous doses of colistin during acute respiratory exacerbations in adults with cystic fibrosis and chronic Pseudomonas aeruginosa infection...
  19. pmc Ten years of viral and non-bacterial serology in adults with cystic fibrosis
    I J Clifton
    Regional Cystic Fibrosis Unit, Seacroft Hospital, Leeds, UK
    Epidemiol Infect 136:128-34. 2008
    ..Adults with CF have a lower incidence of respiratory viral infections associated with pulmonary exacerbations requiring intravenous antibiotics compared to children and infants with CF...
  20. ncbi request reprint Nebulized antibiotic therapy: the evidence
    S P Conway
    Cystic Fibrosis Services, St James Hospital, Leeds, UK
    Chron Respir Dis 2:35-41. 2005
    ..Inhalation of antibiotics may provoke bronchospasm and patients should be assessed before and after treatment prior to continuing long-term therapy at home...
  21. ncbi request reprint Measurement of urinary N-acetyl-b-D-glucosaminidase in adult patients with cystic fibrosis: before, during and after treatment with intravenous antibiotics
    C Etherington
    Regional Adult Cystic Fibrosis Unit, Seacroft Hospital, Leeds, LS14 6UH, United Kingdom
    J Cyst Fibros 6:67-73. 2007
    ..Routine methods of monitoring renal injury are insensitive. N-acetyl-b-d-glucosaminidase (NAG) is a lysosomal enzyme present in the renal proximal tubular cells, with increased excretion an indicator of renal tubular dysfunction...
  22. ncbi request reprint A pilot study of zafirlukast as an anti-inflammatory agent in the treatment of adults with cystic fibrosis
    S P Conway
    Regional Adult CF Unit, Seacroft Hospital, York Road, Leeds, UK
    J Cyst Fibros 2:25-8. 2003
    ..The aim of this study was to assess the efficacy of the leukotriene receptor antagonist zafirlukast as a potential anti-inflammatory agent in the treatment of adult patients with cystic fibrosis...
  23. ncbi request reprint Peripherally inserted central catheters in children with cystic fibrosis. Eight cases of difficult removal
    L S Miall
    University of Leeds, Leeds, United Kingdom
    J Infus Nurs 24:297-300. 2001
    ..The cases were observed in a regional pediatric CF unit in the United Kingdom. Possible etiology and strategies that can be used to achieve catheter removal are discussed...
  24. doi request reprint Acute Burkholderia cenocepacia pyomyositis in a patient with cystic fibrosis
    A H El-Laboudi
    Leeds Adult Cystic Fibrosis Unit, St James s University Hospital, Leeds, UK
    J Cyst Fibros 8:273-5. 2009
    ..To the best of the authors' knowledge no case of pyomyositis secondary to Bcc infection has been reported previously...
  25. ncbi request reprint Evaluation of fecal pancreatic elastase-1 as a measure of pancreatic exocrine function in children with cystic fibrosis
    A Cade
    Regional Paediatric Cystic Fibrosis Unit, St James s University Hospital, Leeds, UK
    Pediatr Pulmonol 29:172-6. 2000
    ..The low values in the first 2 weeks in some normal and premature infants, and the persisting normal values in PS infants, make the fecal EL-1 test unsuitable for neonatal CF screening...
  26. doi request reprint Respiratory exacerbations in childhood associated with compound heterozygosity Phe508del/Arg117His-7T of the cystic fibrosis transmembrane regulator gene
    T W R Lee
    Leeds Regional Paediatric Cystic Fibrosis Centre, St James s University Hospital, Leeds, United Kingdom
    Acta Paediatr 97:670-2. 2008
    ..Conclusion: The compound heterozygote cystic fibrosis (CF) mutation Phe508del with Arg117His-7T should not necessarily be considered benign in childhood...
  27. ncbi request reprint Stenotrophomonas maltophilia contamination of nebulizers used to deliver aerosolized therapy to inpatients with cystic fibrosis
    M Denton
    Department of Microbiology, The General Infirmary at Leeds, Leeds Teaching Hospitals Trust, LS1 3EX, Leeds, UK
    J Hosp Infect 55:180-3. 2003
    ..Although the actual source of S. maltophilia contamination of hospital-use nebulizer equipment in this study remained elusive, these results have important infection control implications...
  28. ncbi request reprint Immunoglobulin and IgG subclass levels in a regional pediatric cystic fibrosis clinic
    J P Garside
    Department of Paediatrics and Child Health, Leeds General Infirmary, Leeds, UK
    Pediatr Pulmonol 39:135-40. 2005
    ..The high percentage of patients with low IgG2 was unexpected and was not previously reported. The clinical significance of this in patients with CF is unknown...
  29. doi request reprint Nutritional decline in cystic fibrosis related diabetes: the effect of intensive nutritional intervention
    H White
    Adult Cystic Fibrosis Unit, St James Hospital, Leeds, UK Leeds Metropolitan University, Leeds, UK
    J Cyst Fibros 8:179-85. 2009
    ..Our aim was to establish whether intensive nutritional intervention prevents pre-diabetic nutritional decline in an adult population with CFRD...
  30. ncbi request reprint The role of IDA scintigraphy in the follow-up of liver disease in patients with cystic fibrosis
    J A Foster
    Department of Clinical Radiology, St James s University Hospital, Leeds, UK
    Nucl Med Commun 23:673-81. 2002
    ..If early detection of disease progression would affect management, patients will continue to require a number of investigations rather than a single test...
  31. doi request reprint An aerobiological model of aerosol survival of different strains of Pseudomonas aeruginosa isolated from people with cystic fibrosis
    I J Clifton
    Regional Cystic Fibrosis Unit, St James University Hospital, Beckett Street, Leeds, United Kingdom
    J Cyst Fibros 9:64-8. 2010
    ..Expression of a mucoid phenotype by the strains of P. aeruginosa isolated from people with CF promoted survival in the aerosol model compared to strains expressing a non-mucoid phenotype...
  32. pmc Methicillin resistant Staphylococcus aureus (MRSA) infection in cystic fibrosis
    L S Miall
    Regional Paediatric Cystic Fibrosis Unit, Children s Day Hospital, St James s University Hospital, Beckett Street, Leeds LS9 7TF, UK
    Arch Dis Child 84:160-2. 2001
    ..Methicillin resistant Staphylococcus aureus (MRSA) infection is increasingly found in patients with cystic fibrosis (CF)...
  33. ncbi request reprint Predictors of desaturation during formal hypoxic challenge in adult patients with cystic fibrosis
    D Peckham
    Regional Adult Cystic Fibrosis Unit, Seacroft Hospital, York Road, Leeds LS14 6UH, UK
    J Cyst Fibros 1:281-6. 2002
    ..No individual clinical parameter appears to fully predict the need for in flight oxygen but patients most at risk appear to have either a low FEV(1) (<60%), high N score (>13) or low baseline PaO(2) (<10.5 kPa)...
  34. ncbi request reprint Treatment of resistant distal intestinal obstruction syndrome with a modified antegrade continence enema procedure
    I J Clifton
    Regional Adult Cystic Fibrosis Unit, Seacroft Hospital, Leeds, UK
    J Cyst Fibros 3:273-5. 2004
    ..She underwent a modified antegrade continence enema procedure. She currently irrigates her conduit every 2-3 days. She has had no further symptoms of distal intestinal obstruction syndrome...
  35. ncbi request reprint Dietary intakes in adult patients with cystic fibrosis--do they achieve guidelines?
    H White
    Dietetic Department, Seacroft Hospital, York Road, Leeds, England, LS14 6UH, UK
    J Cyst Fibros 3:1-7. 2004
    ..There are few data on dietary intakes of adult patients. The aim of this study was to determine nutritional intakes in an adult population with CF. The impact of nutritional intervention and disease on macronutrient intake was examined...
  36. ncbi request reprint Delayed diagnosis of cystic fibrosis associated with R117H on a background of 7T polythymidine tract at intron 8
    D Peckham
    Adult CF Unit, Seacroft Hospital, Leeds, United Kingdom
    J Cyst Fibros 5:63-5. 2006
    ..Patients with two identified CFTR mutations which include the R117H/7T anomaly should be followed up routinely as they remain susceptible to severe lung disease...
  37. ncbi request reprint Reduction in prevalence of chronic Pseudomonas aeruginosa infection at a regional pediatric cystic fibrosis center
    Tim W R Lee
    Leeds Regional Paediatric Cystic Fibrosis Unit, St James s University Hospital, Leeds, United Kingdom
    Pediatr Pulmonol 37:104-10. 2004
    ..aeruginosa did not alter significantly. In conclusion, antipseudomonal management strategies were associated with both reduced prevalence, and an increase in the mean age of onset of chronic P. aeruginosa infection...
  38. ncbi request reprint Evidence-based medicine in cystic fibrosis: how should practice change?
    Steven P Conway
    Department of Pediatrics, St James s and Seacroft Hospitals, Leeds, United Kingdom
    Pediatr Pulmonol 34:242-7. 2002
    ....
  39. ncbi request reprint Therapeutic drug monitoring of once daily tobramycin in cystic fibrosis--caution with trough concentrations
    Kingsley P Coulthard
    Adelaide Women s and Children s Hospital, Pharmacy Department, Australia
    J Cyst Fibros 6:125-30. 2007
    ..This study aimed to compare the exposures to ODD of tobramycin in adults and children with cystic fibrosis using the AUC and trough TDM approaches...
  40. ncbi request reprint Risk factors for acquisition of methicillin-resistant Staphylococcus aureus (MRSA) by patients with cystic fibrosis
    Kavitha Nadesalingam
    Division of Microbiology, University of Leeds, Leeds, UK
    J Cyst Fibros 4:49-52. 2005
    ..Minimising the number and length of hospital admissions and judicious use of antibiotics, particularly ciprofloxacin, should be the key components of any strategies designed to reduce the risk of MRSA acquisition by patients with CF...
  41. ncbi request reprint Alcaligenes infection in cystic fibrosis
    Kenneth Tan
    Regional Cystic Fibrosis Unit, St James s and Seacroft University Hospitals, Leeds, United Kingdom
    Pediatr Pulmonol 34:101-4. 2002
    ..Chronically infected patients showed no excess deterioration in clinical or pulmonary function status from 2 years before to 2 years after primary acquisition...
  42. ncbi request reprint Associations between clinical variables and quality of life in adults with cystic fibrosis
    Louise Gee
    Faculty of Health, University of Central Lancashire, Preston, Lancashire PR1 2HE, UK
    J Cyst Fibros 4:59-66. 2005
    ..This cross-sectional study explored associations between clinical variables and HRQoL...
  43. ncbi request reprint Cystic fibrosis presenting as acute pancreatitis and obstructive azoospermia in a young adult male with a novel mutation in the CFTR gene
    Steven P Conway
    Regional Cystic Fibrosis Unit, Seacroft Hospital, Leeds, UK
    Pediatr Pulmonol 34:491-5. 2002
    ..Patients with cystic fibrosis and unexplained upper abdominal pain should be screened for pancreatitis, and consideration should be given to screening patients with idiopathic pancreatitis for mutations in the CFTR gene...
  44. ncbi request reprint Diagnosis and treatment of intestinal malabsorption in cystic fibrosis
    James M Littlewood
    Regional Paediatric Cystic Fibrosis Unit, St James s University Hospital, Leeds, UK
    Pediatr Pulmonol 41:35-49. 2006
    ....
  45. ncbi request reprint Transition programs in cystic fibrosis centers
    Steven P Conway
    Pediatr Pulmonol 37:1-3. 2004
  46. ncbi request reprint Aspergillus bronchitis in cystic fibrosis
    David Shoseyov
    Department of Pediatrics and CF Center, Hadassah University Hospital, Mount Scopus, Jerusalem, Israel
    Chest 130:222-6. 2006
    ..Antifungal therapy should be considered when deteriorating respiratory function is not responding to antibacterial therapy and A fumigatus is growing in sputum cultures...
  47. doi request reprint Osteoporosis in cystic fibrosis
    Gerd Doring
    J Pediatr (Rio J) 84:1-3. 2008
  48. ncbi request reprint Evaluation of a new definition for chronic Pseudomonas aeruginosa infection in cystic fibrosis patients
    Tim W R Lee
    Leeds Regional Paediatric Cystic Fibrosis Centre, St James s Hospital, Leeds, UK
    J Cyst Fibros 2:29-34. 2003
    ....
  49. ncbi request reprint Nutritional status, perceived body image and eating behaviours in adults with cystic fibrosis
    Janice Abbott
    Faculty of Health, University of Central Lancashire, Preston, PR1 2HE, UK
    Clin Nutr 26:91-9. 2007
    ..This work aimed to provide a psychosocial profile and compare CF patients receiving (a) enteral tube feeding, (b) nutritional supplements, (c) no nutritional interventions, and (d) healthy controls...
  50. ncbi request reprint Nutritional intake and status in children with cystic fibrosis: does age matter?
    Helen White
    Adult Cystic Fibrosis Unit, Seacroft Hospital, Leeds, UK
    J Pediatr Gastroenterol Nutr 44:116-23. 2007
    ..To determine whether nutritional intake and status vary with age in children with cystic fibrosis (CF)...