Paul Collinson

Summary

Affiliation: St George's Hospital
Country: UK

Publications

  1. ncbi request reprint Biomarkers of cardiovascular damage and dysfunction--an overview
    Paul O Collinson
    Departments of Chemical Pathology, Cardiac Research and Cardiology, St George s Hospital and Medical School, Blackshaw Road, London SW17 0QT, United Kingdom
    Heart Lung Circ 16:S71-82. 2007
  2. doi request reprint Cardiac biomarkers in chronic renal disease
    Paul O Collinson
    Department of Chemical Pathology, St George s Hospital, London, UK
    Scand J Clin Lab Invest Suppl 241:104-8. 2008
  3. doi request reprint Randomised Assessment of Treatment using Panel Assay of Cardiac markers--Contemporary Biomarker Evaluation (RATPAC CBE)
    P O Collinson
    Clinical Blood Sciences Laboratory, St George s Hospital, London, UK
    Health Technol Assess 17:v-vi, 1-122. 2013
  4. ncbi request reprint Republished: Sensitive troponin assays
    Paul O Collinson
    Department of Cardiology, St George s Hospital and Medical School, London SW17 0RE, UK
    Postgrad Med J 88:348-52. 2012
  5. doi request reprint Very early diagnosis of chest pain by point-of-care testing: comparison of the diagnostic efficiency of a panel of cardiac biomarkers compared with troponin measurement alone in the RATPAC trial
    Paul Collinson
    Department of Clinical Blood Sciences, St George s Hospital, Ground Floor, Jenner Wing, London SW17 0QT, UK
    Heart 98:312-8. 2012
  6. doi request reprint Influence of population selection on the 99th percentile reference value for cardiac troponin assays
    Paul O Collinson
    Department of Cardiology, St George s Hospital, London, UK
    Clin Chem 58:219-25. 2012
  7. ncbi request reprint Biomarkers of cardiovascular damage
    Paul O Collinson
    Departments of Chemical Pathology, Cardiac Research and Cardiology, St George s Hospital and Medical School, London, UK
    Med Princ Pract 16:247-61. 2007
  8. ncbi request reprint Comparison of biomarker strategies for rapid rule out of myocardial infarction in the emergency department using ACC/ESC diagnostic criteria
    Paul O Collinson
    Department of Chemical Pathology, 2nd Floor Jenner Wing, St George s Hospital, Blackshaw Road, London SW17 0QT, UK
    Ann Clin Biochem 43:273-80. 2006
  9. pmc Cardiac troponins in intensive care
    Paul Collinson
    Department of Chemical Pathology, St George s Healthcare NHS Trust, London, UK
    Crit Care 9:345-6. 2005
  10. ncbi request reprint The cost effectiveness of B-Type natriuretic peptide measurement in the primary care setting-a UK perspective
    Paul O Collinson
    Department of Chemical Pathology, St George s Hospital, London, England
    Congest Heart Fail 12:103-7. 2006

Collaborators

Detail Information

Publications67

  1. ncbi request reprint Biomarkers of cardiovascular damage and dysfunction--an overview
    Paul O Collinson
    Departments of Chemical Pathology, Cardiac Research and Cardiology, St George s Hospital and Medical School, Blackshaw Road, London SW17 0QT, United Kingdom
    Heart Lung Circ 16:S71-82. 2007
    ..The role of the B type natriuretic peptides in detection of cardiac failure, acute and chronic, is well defined. Their role in ACS remains the subject of further studies...
  2. doi request reprint Cardiac biomarkers in chronic renal disease
    Paul O Collinson
    Department of Chemical Pathology, St George s Hospital, London, UK
    Scand J Clin Lab Invest Suppl 241:104-8. 2008
    ..The challenge is for the renal physician to translate the potential for cardiovascular disease monitoring conferred by these biomarkers into improved patient management...
  3. doi request reprint Randomised Assessment of Treatment using Panel Assay of Cardiac markers--Contemporary Biomarker Evaluation (RATPAC CBE)
    P O Collinson
    Clinical Blood Sciences Laboratory, St George s Hospital, London, UK
    Health Technol Assess 17:v-vi, 1-122. 2013
    ....
  4. ncbi request reprint Republished: Sensitive troponin assays
    Paul O Collinson
    Department of Cardiology, St George s Hospital and Medical School, London SW17 0RE, UK
    Postgrad Med J 88:348-52. 2012
    ....
  5. doi request reprint Very early diagnosis of chest pain by point-of-care testing: comparison of the diagnostic efficiency of a panel of cardiac biomarkers compared with troponin measurement alone in the RATPAC trial
    Paul Collinson
    Department of Clinical Blood Sciences, St George s Hospital, Ground Floor, Jenner Wing, London SW17 0QT, UK
    Heart 98:312-8. 2012
    ..To assess the impact of triple marker testing on patient management and the diagnostic efficiencies of different biomarker strategies examined...
  6. doi request reprint Influence of population selection on the 99th percentile reference value for cardiac troponin assays
    Paul O Collinson
    Department of Cardiology, St George s Hospital, London, UK
    Clin Chem 58:219-25. 2012
    ..We sought to determine the effect of patient selection on the 99th reference percentile of 2 sensitive and 1 high-sensitivity (hs) cardiac troponin assays in a well-defined reference population...
  7. ncbi request reprint Biomarkers of cardiovascular damage
    Paul O Collinson
    Departments of Chemical Pathology, Cardiac Research and Cardiology, St George s Hospital and Medical School, London, UK
    Med Princ Pract 16:247-61. 2007
    ..The role of the B-type natriuretic peptides in detection of cardiac failure, both acute and chronic, is well defined but remains the subject of further studies, in ACS...
  8. ncbi request reprint Comparison of biomarker strategies for rapid rule out of myocardial infarction in the emergency department using ACC/ESC diagnostic criteria
    Paul O Collinson
    Department of Chemical Pathology, 2nd Floor Jenner Wing, St George s Hospital, Blackshaw Road, London SW17 0QT, UK
    Ann Clin Biochem 43:273-80. 2006
    ..All three markers were examined prospectively in patients presenting to the Emergency Department (ED) for rule out of AMI...
  9. pmc Cardiac troponins in intensive care
    Paul Collinson
    Department of Chemical Pathology, St George s Healthcare NHS Trust, London, UK
    Crit Care 9:345-6. 2005
    ....
  10. ncbi request reprint The cost effectiveness of B-Type natriuretic peptide measurement in the primary care setting-a UK perspective
    Paul O Collinson
    Department of Chemical Pathology, St George s Hospital, London, England
    Congest Heart Fail 12:103-7. 2006
  11. ncbi request reprint Analytical performance of the N terminal pro B type natriuretic peptide (NT-proBNP) assay on the Elecsys 1010 and 2010 analysers
    P O Collinson
    Department of Chemical Pathology, St George s Hospital, Blackshaw Road, London, SW17 0QT, UK
    Eur J Heart Fail 6:365-8. 2004
    ..89) with NT-proBNP values approximately 5 times greater than BNP (Biosite Triage). In a subset of 320 with normal ejection fraction (>50%) and no risk factors, NT-proBNP values increased with age and were higher in women than men...
  12. ncbi request reprint Diagnostic and prognostic role of cardiac troponin I (cTnI) measured on the DPC Immulite
    P O Collinson
    Department of Chemical Pathology, 2nd Floor Jenner Wing, St George s Hospital, Blackshaw Road, London SW17 0QT, UK
    Clin Biochem 39:692-6. 2006
    ..To evaluate the diagnostic and prognostic role of the Immulite cTnI assay for the detection of acute coronary syndromes (ACS)...
  13. pmc Utility of admission cardiac troponin and "Ischemia Modified Albumin" measurements for rapid evaluation and rule out of suspected acute myocardial infarction in the emergency department
    P O Collinson
    Chemical Pathology, St George s Healthcare NHS Trust, London, UK
    Emerg Med J 23:256-61. 2006
    ..To assess if the combination of cardiac troponin (cTn) and Ischemia Modified Albumin (IMA) can be used for early exclusion of acute myocardial infarction (AMI)...
  14. doi request reprint Cardiac troponin I measurement using the ACS:180 to predict four-year cardiac event rate
    Paul O Collinson
    Department of Chemical Pathology, 2nd Floor Jenner Wing, St George s Hospital and Medical School, Blackshaw Road, London SW17 0QT, UK
    Ann Clin Biochem 45:184-8. 2008
    ..All patients were followed up for a maximum of 4.3 years and cardiac events, either cardiac death, readmission with acute myocardial infarction or admission with acute unstable angina were documented...
  15. ncbi request reprint A prospective randomized controlled trial of point-of-care testing on the coronary care unit
    P O Collinson
    Department of Chemical Pathology, Mayday University Hospital, Croydon, Surrey CR7 7YE, UK
    Ann Clin Biochem 41:397-404. 2004
    ..We report the results of a prospective randomized controlled trial comparing point-of-care testing (POCT) with central laboratory testing (CLT) in a six-bed coronary care unit in a district general hospital...
  16. pmc Natriuretic peptide determinations in critical care medicine: part of routine clinical practice or research test only?
    Paul O Collinson
    Department of Chemical Pathology, St George s Hospital and Medical School, London, UK
    Crit Care 13:105. 2009
    ....
  17. pmc Multicentre evaluation of the diagnostic value of cardiac troponin T, CK-MB mass, and myoglobin for assessing patients with suspected acute coronary syndromes in routine clinical practice
    P O Collinson
    Department of Chemical Pathology, St George s Hospital, London, UK
    Heart 89:280-6. 2003
    ..To assess the diagnostic efficiency of the third generation cardiac troponin T assay in routine clinical practice...
  18. ncbi request reprint Impact of European Society of Cardiology/American College of Cardiology guidelines on diagnostic classification of patients with suspected acute coronary syndromes
    P O Collinson
    Department of Chemical Pathology, Mayday University Hospital, Thornton Heath, Surrey, UK
    Ann Clin Biochem 40:156-60. 2003
    ..Assessment of the relative diagnostic accuracy of investigation strategies for patients with suspected acute coronary syndromes (ACS)...
  19. doi request reprint Sensitive troponin assays
    Paul O Collinson
    Department of Cardiology, St George s Hospital and Medical School, London, UK
    J Clin Pathol 64:845-9. 2011
    ....
  20. ncbi request reprint Ischemia Modified Albumin for the assessment of patients presenting to the emergency department with acute chest pain but normal or non-diagnostic 12-lead electrocardiograms and negative cardiac troponin T
    Debashis Roy
    Department of Cardiological Sciences, St George s Hospital Medical School, Cranmer Terrace, London SW17 0RE, UK
    Int J Cardiol 97:297-301. 2004
    ..Ischemia Modified Albumin (IMA) is a new biochemical marker of ischemia, which may be useful to characterise acute coronary syndrome (ACS) patients...
  21. doi request reprint Comparison of contemporary troponin assays with the novel biomarkers, heart fatty acid binding protein and copeptin, for the early confirmation or exclusion of myocardial infarction in patients presenting to the emergency department with chest pain
    Paul Collinson
    Department of Clinical Blood Sciences, St George s Hospital and Medical School, London, UK
    Heart 100:140-5. 2014
    ..To examine the diagnostic accuracy of novel biomarkers of myocardial injury and troponin assays for diagnosis of myocardial infarction...
  22. ncbi request reprint Novel application of flow propagation velocity and ischaemia-modified albumin in analysis of postexercise cardiac function in man
    Natalie Middleton
    Centre for Sports Medicine and Human Performance, Brunel University, London, UK
    Exp Physiol 91:511-9. 2006
    ..Future studies in this area should investigate alternative diagnostic tools for the detection of transient ischaemia, and other potential mechanisms, in order to extend the understanding of this phenomenon...
  23. ncbi request reprint Effect of radiofrequency catheter ablation on the biochemical marker ischemia modified albumin
    Debashis Roy
    Cardiological Sciences, St George s Hospital Medical School, London, United Kingdom
    Am J Cardiol 94:234-6. 2004
    ..IMA levels have been shown to increase in patients after RF catheter ablation compared with those who undergo diagnostic electrophysiologic studies. The results of this study suggest that IMA may be a marker of myocardial injury...
  24. ncbi request reprint Ischemia-modified albumin concentrations should be interpreted with caution in patients with low serum albumin concentrations
    David C Gaze
    Department of Chemical Pathology, St George s Healthcare NHS Trust, London, UK
    Med Princ Pract 15:322-4. 2006
    ..Ischemia-modified albumin (IMA((R))) is a novel marker for assessing cardiac ischaemia. We assessed the relationship between total albumin concentrations and IMA in serum to investigate whether interpretation of IMA was albumin-dependent...
  25. ncbi request reprint The cardiospecificity of the third-generation cTnT assay after exercise-induced muscle damage
    Robert Shave
    British Olympic Medical Centre, Northwick Park, Harrow, London, UK
    Med Sci Sports Exerc 34:651-4. 2002
    ....
  26. pmc Plasma DNA concentration as a predictor of mortality and sepsis in critically ill patients
    Andrew Rhodes
    Intensive Care Unit, St Georges s Hospital, London, UK
    Crit Care 10:R60. 2006
    ..The present study assesses the significance of raised levels of plasma DNA on admission to the intensive care unit (ICU) in terms of its ability to predict disease severity or prognosis...
  27. ncbi request reprint Interpretation of cardiac troponin measurements in neonates--the devil is in the details. Commentary to trevisanuto et Al.: cardiac troponin I in asphyxiated neonates (biol neonate 2006;89:190-193)
    David C Gaze
    Chemical Pathology, St George s Healthcare NHS Trust, London, UK
    Biol Neonate 89:194-6. 2006
  28. ncbi request reprint Cardiac troponins as biomarkers of drug- and toxin-induced cardiac toxicity and cardioprotection
    David C Gaze
    St George s Hospital, Chemical Pathology, Blackshaw Road, Tooting, London SW17 0QT, UK
    Expert Opin Drug Metab Toxicol 1:715-25. 2005
    ..cTnT and cTnI are now being adopted as sensitive biomarkers of drug-induced cardiac toxicity...
  29. ncbi request reprint Ischemia modified albumin is a sensitive marker of myocardial ischemia after percutaneous coronary intervention
    Manas K Sinha
    Coronary Artery Disease Research Unit, St George s Hospital, London, UK
    Circulation 107:2403-5. 2003
    ..It is not known whether IMA elevations correlate with increases in other markers of oxidative stress, ie, 8-iso prostaglandin F2-A (iP)...
  30. ncbi request reprint Evidence of cardiomyocyte necrosis in glycogen storage disease type II
    David C Gaze
    Chemical Pathology, St George s Hospital, Blackshaw Road, Tooting, London SW17 0QT, UK
    Ann Clin Biochem 44:86-8. 2007
    ..1 microg/L using a Cardiac Reader, subsequently confirmed on an Elecsys 1010 (both from Roche Diagnostics, Lewes, UK). cTnT may therefore be a useful biomarker in examining subclinical cardiac involvement in GSD-II patients...
  31. doi request reprint Effect of atrioventricular optimization on circulating N-terminal pro brain natriuretic peptide following cardiac resynchronization therapy
    Nesan Shanmugam
    St George s Healthcare NHS Trust, Department of Cardiology, Blackshaw Road, London, UK
    Eur J Heart Fail 15:534-42. 2013
    ..Following CRT, atrioventricular (AV) optimization is not routinely practised. To evaluate its clinical utility, we examined the effect of AV delay optimization on the prognostic biomarker NT-proBNP...
  32. ncbi request reprint Investigation of cardiac troponins in postmortem subjects: comparing antemortem and postmortem levels
    Susan J Davies
    Histopathology Department, Royal Brompton Hospital, London, United Kingdom
    Am J Forensic Med Pathol 26:213-5. 2005
    ..In addition, the results of our study support the view that elevated cardiac troponins are a marker of serious morbidity and are not specific for cardiac injury as the primary cause of morbidity or mortality...
  33. ncbi request reprint Evaluation of ischaemia-modified albumin as a marker of myocardial ischaemia in end-stage renal disease
    Rajan Sharma
    Department of Cardiology, St George s Hospital, Cranmer Terrace, London, UK
    Clin Sci (Lond) 113:25-32. 2007
    ..02). In conclusion, IMA is a moderately accurate marker of myocardial ischaemia in ESRD. Patients with an increase in IMA > or = 20 kU/l during DSE had significantly worse survival...
  34. ncbi request reprint Ischemia-modified albumin predicts mortality in ESRD
    Rajan Sharma
    Department of Cardiology, St George s Hospital, London, UK
    Am J Kidney Dis 47:493-502. 2006
    ..The primary study aim is to determine whether ischemia-modified albumin (IMA) levels predict mortality in patients with end-stage renal disease (ESRD). The secondary aim is to determine characteristics of patients with elevated IMA levels...
  35. ncbi request reprint The British Cardiac Society on the redefinition of myocardial infarction: a basis for discussion
    Paul Collinson
    Departments of Chemical Pathology and Cardiology, St George s Healthcare NHS Trust, Blackshaw Road, Tooting, London SW17 0QT, UK
    Ann Clin Biochem 41:258-9. 2004
  36. ncbi request reprint Mitral peak Doppler E-wave to peak mitral annulus velocity ratio is an accurate estimate of left ventricular filling pressure and predicts mortality in end-stage renal disease
    Rajan Sharma
    Department of Cardiology, Chemical Pathology, St George s Hospital, London, United Kingdom
    J Am Soc Echocardiogr 19:266-73. 2006
    ..The study aimed to assess whether the mitral peak Doppler E-wave to peak mitral annulus velocity ratio (E/Ea) estimates left ventricular (LV) filling pressure (LVFP) and predicts mortality in end-stage renal disease...
  37. ncbi request reprint Usefulness of N-terminal pro-B-type natriuretic peptide levels to predict exercise capacity in hypertrophic cardiomyopathy
    Rajesh Thaman
    The Heart Hospital, University College London, London, United Kingdom
    Am J Cardiol 98:515-9. 2006
    ..616) for predicting percent VO2max < 80%. In conclusion, NT-pro-BNP levels correlate with peak oxygen consumption in HC and are more predictive of functional impairment than other conventional markers of disease severity...
  38. ncbi request reprint Biomarkers in angina
    Paul O Collinson
    Dept Chemical Pathology, Cardiology, St George s Hospital and Medical School, London, UK
    Scand J Clin Lab Invest Suppl 240:86-92. 2005
    ..Ischaemia modified albumin is currently the most promising of the markers for early detection of ischaemia at first presentation...
  39. ncbi request reprint Clinical effect of recalibration of the roche cardiac troponin T assay
    David C Gaze
    Department of Chemical Pathology, St George s Healthcare NHS Trust, London, UK
    Med Princ Pract 15:29-32. 2006
    ..To assess the effect of recalibration of the Roche 3rd-generation cTnT assay with recombinant human cardiac troponin T (cTnT) standards on clinical decision limits...
  40. ncbi request reprint Markers of muscle ischemia, necrosis, and inflammation following uterine artery embolization in the treatment of symptomatic uterine fibroids
    Nassera S Banu
    Department of Clinical Development Sciences, St George s University of London, London, United Kingdom
    Am J Obstet Gynecol 196:213.e1-5. 2007
    ..The objective of the study was to quantify markers of myometrial ischemia, necrosis, and inflammation in women undergoing uterine artery embolization (UAE)...
  41. ncbi request reprint Mitral annular calcification predicts mortality and coronary artery disease in end stage renal disease
    Rajan Sharma
    Department of Cardiology, St George s Hospital, London, United Kingdom
    Atherosclerosis 191:348-54. 2007
    ..We sought to determine whether mitral annular calcification (MAC) predicts mortality and cardiac disease in a group of renal transplant candidates...
  42. doi request reprint Multiple molecular forms of circulating cardiac troponin: analytical and clinical significance
    David C Gaze
    Chemical Pathology, St George s Hospital, Blackshaw Road, Tooting, London SW17 0QT, UK
    Ann Clin Biochem 45:349-55. 2008
    ..However, the effects of these multiple forms on commercial assay performance and their impact clinically are currently unknown and should be the focus of future research and assay design...
  43. ncbi request reprint Diagnosing hypovitaminosis D: serum measurements of calcium, phosphate, and alkaline phosphatase are unreliable, even in the presence of secondary hyperparathyroidism
    G Richard Smith
    Department of Rheumatology, St George s Healthcare NHS Trust, London, England
    J Rheumatol 32:684-9. 2005
    ..To ascertain the ability of routine biochemical markers of bone turnover to predict vitamin D insufficiency...
  44. ncbi request reprint Dynamic left ventricular obstruction: a potential cause of angina in end stage renal disease
    Rajan Sharma
    Department of Cardiology, St George s Hospital, London, United Kingdom
    Int J Cardiol 112:295-301. 2006
    ..Symptoms are often attributed to systolic and diastolic dysfunction, arrhythmia or microvascular disease. This study proposes another potential cause for angina in renal failure, namely dynamic left ventricular obstruction (LVO)...
  45. ncbi request reprint Multicentre evaluation of a new point-of-care test for the determination of NT-proBNP in whole blood
    Christian Zugck
    Abteilung fur Kardiologie, Angiologie und Pulmonologie, Universitatsklinikum Heidelberg, Heidelberg, Germany
    Clin Chem Lab Med 44:1269-77. 2006
    ....
  46. ncbi request reprint Increased left atrial volume index is an independent predictor of raised serum natriuretic peptide in patients with suspected heart failure but normal left ventricular ejection fraction: Implication for diagnosis of diastolic heart failure
    Tiong K Lim
    Department of Cardiovascular Medicine, Northwick Park Hospital, Watford Road, Harrow, Middlesex, HA1 3UJ, UK
    Eur J Heart Fail 8:38-45. 2006
    ..We assessed the capacity of LAVI to predict LV diastolic dysfunction in comparison with N-terminal pro B-type natriuretic peptide (NTproBNP) in patients with suspected heart failure and a normal ejection fraction (EF)...
  47. ncbi request reprint Cardiac troponin determination in amniotic fluid
    David C Gaze
    Croat Med J 46:999-1000; discussion 1000-1. 2005
  48. ncbi request reprint Risk stratification of chest pain patients by point-of-care cardiac troponin T and myoglobin measured in the emergency department
    Jordi Ordonez-Llanos
    Hospital de la Santa Creu i Sant Pau, Barcelona, Spain
    Clin Chim Acta 365:93-7. 2006
    ....
  49. ncbi request reprint Measurement of cardiac troponin I in striated muscle using three experimental methods
    Salim Fredericks
    Analytical Unit, Cardiological Sciences, St George s Hospital Medical School, London SW17 0RE, UK
    Ann Clin Biochem 40:244-8. 2003
    ..Each of these forms can change the antigenicity of cTnI, resulting in different antibody-antigen interactions in different experimental formats, thereby giving rise to the disparities in the literature...
  50. ncbi request reprint Cost effectiveness of the B type natriuretic peptide, electrocardiography, and portable echocardiography for the assessment of patients from the community with suspected heart failure
    Tiong Keng Lim
    Department of Cardiovascular Medicine, Northwick Park Hospital, Harrow, UK
    Echocardiography 24:228-36. 2007
    ....
  51. ncbi request reprint Surveys on the use of cardiac markers in the UK
    Wing Man Tsang
    Department of Clinical Biochemistry, Royal Hospital Haslar, Gosport, UK
    Ann Clin Biochem 40:138-42. 2003
    ..However, it is not known how widespread is the adoption of these new strategies across the UK...
  52. ncbi request reprint Cardiac troponin-I content of skeletal muscle in patients with renal failure
    Salim Fredericks
    Analytical Unit, Cardiological Sciences, St George s Hospital Medical School, London SW17 0RE, UK
    Clin Biochem 35:421-3. 2002
  53. ncbi request reprint Cardiac troponin T and creatine kinase MB content in skeletal muscle of the uremic rat
    Salim Fredericks
    Analytical Unit, Cardiological Sciences, St George s Hospital Medical School, London SW17 0RE, United Kingdom
    Clin Chem 48:859-68. 2002
    ..We studied the content of CK-MB and cTnT in skeletal muscle of the renal-insufficient rat...
  54. doi request reprint Amino-terminal pro-B-type natriuretic peptide: analytic considerations
    Jordi Ordonez-Llanos
    Biochemistry Service, Hospital de la Santa Creu i Sant Pau, and the Department of Biochemistry and Molecular Biology, Universitat Autonoma, Barcelona, Spain
    Am J Cardiol 101:9-15. 2008
    ..When analyzed in patients with stable heart failure, biologic variability was 25%-40%. This article reviews the laboratory aspects of NT-proBNP testing from the perspective of the clinical laboratorian...
  55. doi request reprint Amino-terminal pro-B-type natriuretic peptide testing to assist the diagnostic evaluation of heart failure in symptomatic primary care patients
    Per Hildebrandt
    Department of Internal Medicine and Cardiology, Roskilde University Hospital, Roskilde, Denmark
    Am J Cardiol 101:25-8. 2008
    ..Conversely, an NT-proBNP result above the age-stratified primary care cut points does not absolutely indicate the presence of HF; a more directed cardiovascular workup is indicated...
  56. ncbi request reprint Meta-analysis of ischemia-modified albumin to rule out acute coronary syndromes in the emergency department
    Frank Peacock
    Department of Emergency Medicine, The Cleveland Clinic Foundation, Cleveland, OH 44195, USA
    Am Heart J 152:253-62. 2006
    ..Ischemia-modified albumin (IMA), a serum biomarker with a high negative predictive value (NPV) at ED presentation, may exclude ACS. Our objective was to perform a meta-analysis of IMA use for ACS risk stratification...
  57. ncbi request reprint Value of primary care electrocardiography for the prediction of left ventricular systolic dysfunction in patients with suspected heart failure
    Tiong Keng Lim
    Int J Cardiol 115:73-4. 2007
    ..Therefore, measurement of NTproBNP is a better investigation in primary care than ECG for the detection of significant LVSD...
  58. pmc Comparison of the clinical utility of atrial and B type natriuretic peptide measurement for the diagnosis of systolic dysfunction in a low-risk population
    Gavin Galasko
    Department of Cardiovascular Medicine, Northwick Park Hospital, Harrow, Middlesex, UK
    J Clin Pathol 60:570-2. 2007
    ..The study compared measurement of NTproBNP with measurement of N terminal pro-atrial natriuretic peptide (NTproANP) for detection of ventricular systolic dysfunction in primary care...
  59. ncbi request reprint Multicenter analytical performance evaluation of the Elecsys proBNP assay
    Lori J Sokoll
    Johns Hopkins Medical Institutions, Baltimore, MD 21287, USA
    Clin Chem Lab Med 42:965-72. 2004
    ..In summary, the Elecsys proBNP assay exhibits good technical performance and is suitable for use in routine clinical laboratories to aid in the diagnosis of congestive heart failure...
  60. ncbi request reprint Point-of-care testing--can we move from anecdote to evidence?
    Paul O Collinson
    Clin Chem Lab Med 44:1049-51. 2006
  61. ncbi request reprint Dobutamine stress echocardiography and the resting but not exercise electrocardiograph predict severe coronary artery disease in renal transplant candidates
    Rajan Sharma
    Department of Cardiology, E Level East Wing, Mailpoint 46, Southampton General Hospital, Tremona Road, Southampton SO16 6YD, UK
    Nephrol Dial Transplant 20:2207-14. 2005
    ..The aim of this study was to identify non-invasive predictors of severe CAD in a group of renal transplant candidates...
  62. ncbi request reprint Cardiac troponin I should be interpreted with caution in paediatric neonatal patients. Concerning Turker et al.: 'Cord blood cardiac troponin I as an early predictor of short-term outcome in perinatal hypoxia'
    David C Gaze
    Biol Neonate 87:19. 2005
  63. ncbi request reprint First trimester maternal serum ischaemia-modified albumin: a marker of hypoxia-ischaemia-driven early trophoblast development
    Federico Prefumo
    Fetal Medicine Unit, Division of Obstetrics and Gynaecology, St George s University of London, and Department of Clinical Biochemistry, St George s Hospital NHS Trust, London SW17 0RE, UK
    Hum Reprod 22:2029-32. 2007
    ..Ischaemia-modified albumin (IMA) is used in the measurement of cardiac ischaemia. We aimed to test the hypothesis that maternal serum IMA may be elevated in early pregnancy as a measurable manifestation of intrauterine ischaemia...
  64. ncbi request reprint Cardiac troponin for the forensic diagnosis of cardiac contusion
    David C Gaze
    Forensic Sci Int 169:276. 2007
  65. ncbi request reprint Exercise-induced cardiac troponin T release: a meta-analysis
    Robert Shave
    Centre for Sports Medicine and Human Performance, Brunel University, Uxbridge, United Kingdom
    Med Sci Sports Exerc 39:2099-106. 2007
    ..Release of cTnT has been demonstrated in several small studies after endurance exercise. The purpose of this study was to explore, using a meta-analytic approach, the incidence of postexercise cTnT release after endurance exercise...
  66. ncbi request reprint Effect of denervation on the content of cardiac troponin-T and cardiac troponin-I in rat skeletal muscle
    Salim Fredericks
    Institute of Medicine, Universiti Brunei Darussalam, Jalan Tunku Link, Gadong, BE 1410, Brunei Darussalam
    Clin Biochem 40:423-6. 2007
    ..001). These data, combined with data on other models in the literature, indicate that re-expression of cTnT and cTnI isoforms in adult skeletal muscle is unlikely and does not interfere with cTnT assays for assessment of cardiac damage...
  67. doi request reprint Defective endovascular trophoblast invasion in the first trimester is associated with increased maternal serum ischemia-modified albumin
    Aris T Papageorghiou
    Fetal Medicine Unit, Academic Department of Clinical Developmental Sciences, 4th Floor, Lanesborough Wing, St George s, University of London, Cranmer Terrace, London SW17 0RE, UK
    Hum Reprod 23:803-6. 2008
    ..The aim of this study was to examine whether first trimester IMA levels are further elevated with defective trophoblast development...