Rebecca A Charlton

Summary

Affiliation: St George's
Country: UK

Publications

  1. doi Theory of mind associations with other cognitive functions and brain imaging in normal aging
    Rebecca A Charlton
    Clinical Neuroscience, St George s University of London, London, United Kingdom
    Psychol Aging 24:338-48. 2009
  2. doi White matter pathways associated with working memory in normal aging
    Rebecca A Charlton
    Centre for Clinical Neuroscience, Division of Cardiac and Vascular Sciences, St George s University of London, Cranmer Terrace, UK
    Cortex 46:474-89. 2010
  3. doi Diffusion tensor imaging detects age related white matter change over a 2 year follow-up which is associated with working memory decline
    R A Charlton
    Clinical Neuroscience, St George s University of London, London, UK
    J Neurol Neurosurg Psychiatry 81:13-9. 2010
  4. doi The relationship between episodic long-term memory and white matter integrity in normal aging
    R A Charlton
    Clinical Neuroscience, St George s University of London, Cranmer Terrace, London SW17 0RE, UK
    Neuropsychologia 48:114-22. 2010
  5. ncbi The relationship between white matter brain metabolites and cognition in normal aging: the GENIE study
    R A Charlton
    Centre for Clinical Neuroscience, St George s University of London, Cranmer Terrace London, SW17 0RE, UK
    Brain Res 1164:108-16. 2007
  6. ncbi A structural equation modeling investigation of age-related variance in executive function and DTI measured white matter damage
    R A Charlton
    Clinical Neuroscience, St George s University of London, Cranmer Terrace, London SW17 0RE, UK
    Neurobiol Aging 29:1547-55. 2008
  7. doi Diffusion tensor imaging and MR spectroscopy in hypertension and presumed cerebral small vessel disease
    Arani Nitkunan
    Centre for Clinical Neurosciences, St George s, University of London, London, United Kingdom
    Magn Reson Med 59:528-34. 2008
  8. doi Reduced N-acetylaspartate is consistent with axonal dysfunction in cerebral small vessel disease
    Arani Nitkunan
    Centre for Clinical Neuroscience, St George s, University of London, London, UK
    NMR Biomed 22:285-91. 2009
  9. doi Multimodal MRI in cerebral small vessel disease: its relationship with cognition and sensitivity to change over time
    Arani Nitkunan
    Centre for Clinical Neuroscience, St George s, University of London, Cranmer Terrace, London SW17 0RE, UK
    Stroke 39:1999-2005. 2008
  10. doi White matter structural decline in normal ageing: a prospective longitudinal study using tract-based spatial statistics
    Thomas R Barrick
    Centre for Clinical Neuroscience, St George s, University of London, Cranmer Terrace, London, SW17 0RE, UK
    Neuroimage 51:565-77. 2010

Detail Information

Publications19

  1. doi Theory of mind associations with other cognitive functions and brain imaging in normal aging
    Rebecca A Charlton
    Clinical Neuroscience, St George s University of London, London, United Kingdom
    Psychol Aging 24:338-48. 2009
    ..Theory of mind age-related decline may not be independent of other cognitive functions; it may also be particularly susceptible to changes in white matter integrity...
  2. doi White matter pathways associated with working memory in normal aging
    Rebecca A Charlton
    Centre for Clinical Neuroscience, Division of Cardiac and Vascular Sciences, St George s University of London, Cranmer Terrace, UK
    Cortex 46:474-89. 2010
    ..It has been proposed that subtle white matter integrity loss may lead to the disruption of working memory in particular because it relies on the dynamic and reiterative activity of cortico-cortical pathways...
  3. doi Diffusion tensor imaging detects age related white matter change over a 2 year follow-up which is associated with working memory decline
    R A Charlton
    Clinical Neuroscience, St George s University of London, London, UK
    J Neurol Neurosurg Psychiatry 81:13-9. 2010
    ..However, there are few data on whether DTI can detect age related changes over short time periods and whether such change correlates with cognitive function...
  4. doi The relationship between episodic long-term memory and white matter integrity in normal aging
    R A Charlton
    Clinical Neuroscience, St George s University of London, Cranmer Terrace, London SW17 0RE, UK
    Neuropsychologia 48:114-22. 2010
    ..The results suggest that reduced LTM performance in normal aging is related to reduced integrity of a distributed network dependent on white matter pathways supporting episodic memory...
  5. ncbi The relationship between white matter brain metabolites and cognition in normal aging: the GENIE study
    R A Charlton
    Centre for Clinical Neuroscience, St George s University of London, Cranmer Terrace London, SW17 0RE, UK
    Brain Res 1164:108-16. 2007
    ....
  6. ncbi A structural equation modeling investigation of age-related variance in executive function and DTI measured white matter damage
    R A Charlton
    Clinical Neuroscience, St George s University of London, Cranmer Terrace, London SW17 0RE, UK
    Neurobiol Aging 29:1547-55. 2008
    ..Integration of the information processing speed and frontal-executive hypotheses may provide important information regarding common, unique, and mediating factors in cognitive aging...
  7. doi Diffusion tensor imaging and MR spectroscopy in hypertension and presumed cerebral small vessel disease
    Arani Nitkunan
    Centre for Clinical Neurosciences, St George s, University of London, London, United Kingdom
    Magn Reson Med 59:528-34. 2008
    ..457, controls -0.317). NAA is a marker of axonal loss/dysfunction. These findings are consistent with axonal loss/dysfunction being the principal process causing the DTI changes found in cerebral SVD and ageing...
  8. doi Reduced N-acetylaspartate is consistent with axonal dysfunction in cerebral small vessel disease
    Arani Nitkunan
    Centre for Clinical Neuroscience, St George s, University of London, London, UK
    NMR Biomed 22:285-91. 2009
    ..We used (1)H MRS to investigate brain metabolic differences between patients with SVD and controls and correlated this with cognition...
  9. doi Multimodal MRI in cerebral small vessel disease: its relationship with cognition and sensitivity to change over time
    Arani Nitkunan
    Centre for Clinical Neuroscience, St George s, University of London, Cranmer Terrace, London SW17 0RE, UK
    Stroke 39:1999-2005. 2008
    ..In patients with symptomatic sporadic small vessel disease, we determined which MRI parameters best correlated with cognitive function on cross-sectional analysis and which changed over a period of 1 year...
  10. doi White matter structural decline in normal ageing: a prospective longitudinal study using tract-based spatial statistics
    Thomas R Barrick
    Centre for Clinical Neuroscience, St George s, University of London, Cranmer Terrace, London, SW17 0RE, UK
    Neuroimage 51:565-77. 2010
    ..Common changes across different diffusion characteristics are discussed...
  11. doi Brain structure and function in chronic obstructive pulmonary disease: a multimodal cranial magnetic resonance imaging study
    James W Dodd
    Division of Clinical Science, Respiratory Medicine, St George s University of London, Cranmer Terrace, Tooting, London, SW17 0RE, United Kingdom
    Am J Respir Crit Care Med 186:240-5. 2012
    ..Imaging techniques using magnetic resonance (MR) diffusion tensor imaging (DTI) and resting state functional MR imaging (rfMRI) provide measures of white matter microstructure and gray functional activation, respectively...
  12. doi The impact of subcortical white matter disease on mood in euthymic older adults: a diffusion tensor imaging study
    Melissa Lamar
    Department of Psychology, Institute of Psychiatry, King s College, London, UK
    Am J Geriatr Psychiatry 18:634-42. 2010
    ..We aimed to address these issues with non-demented euthymic older adults...
  13. ncbi White matter damage on diffusion tensor imaging correlates with age-related cognitive decline
    R A Charlton
    Clinical Neuroscience, St George s University of London, UK
    Neurology 66:217-22. 2006
    ..Damage to white matter tracts, resulting in "cerebral disconnection," may underlie age-related cognitive decline...
  14. doi Cognitive dysfunction in patients hospitalized with acute exacerbation of COPD
    James W Dodd
    St George s University of London, London, England
    Chest 144:119-27. 2013
    ..Cognitive impairment is one of the least well-studied COPD comorbidities. It is known to occur in hypoxemic patients, but its presence during acute exacerbation is not established...
  15. doi Brain atrophy and cerebral small vessel disease: a prospective follow-up study
    Arani Nitkunan
    Clinical Neuroscience, St George s, University of London, Cranmer Terrace, London SW17 0RE, UK
    Stroke 42:133-8. 2011
    ....
  16. doi Cognitive impairment and white matter damage in hypertension: a pilot study
    K Hannesdottir
    Centre for Clinical Neuroscience, St Georges University of London, UK
    Acta Neurol Scand 119:261-8. 2009
    ..Diffusion tensor imaging (DTI) and magnetic resonance spectroscopy were applied to assess white matter abnormalities in treated vs untreated hypertension and if these correlated with neuropsychological performance...
  17. doi Aging in autism spectrum disorders: a mini-review
    Francesca Happe
    MRC Social, Genetic and Developmental Psychiatry Centre, Institute of Psychiatry, King s College London, London, UK
    Gerontology 58:70-8. 2012
    ....
  18. ncbi Long and short echo time proton magnetic resonance spectroscopic imaging of the healthy aging brain
    Dominick J O McIntyre
    Basic Medical Sciences, St George s University of London, London, UK
    J Magn Reson Imaging 26:1596-606. 2007
    ..To investigate the relationship between subject age and white matter brain metabolite concentrations and R(2) relaxation rates in a cross-sectional study of human brain...
  19. ncbi The cognitive profiles of CADASIL and sporadic small vessel disease
    R A Charlton
    Clinical Neuroscience, St George s University of London, UK
    Neurology 66:1523-6. 2006
    ..To validate CADASIL's use as a model it is important to show it results in a similar cognitive impairment...