A J Camm

Summary

Affiliation: St George's Hospital Medical School
Country: UK

Publications

  1. ncbi request reprint 5-hydroxytryptamine and atrial fibrillation: how significant is this piece in the puzzle?
    Shamil Yusuf
    Department of Cardiovascular Medicine, St Georges Hospital Medical School, London, United Kingdom
    J Cardiovasc Electrophysiol 14:209-14. 2003
  2. ncbi request reprint Turbulence slope after atrial premature complexes is an independent predictor of mortality in survivors of acute myocardial infarction
    Dan Wichterle
    Department of Cardiac and Vascular Sciences, St George s Hospital Medical School, London, United Kingdom
    J Cardiovasc Electrophysiol 15:1350-6. 2004
  3. ncbi request reprint Rate versus rhythm control: is the debate over?
    A John Camm
    Department of Cardiological Sciences, St George s Hospital Medical School, London, UK
    J Interv Card Electrophysiol 7:7-11. 2002
  4. ncbi request reprint Advances in antiarrhythmic drug treatment of atrial fibrillation: where do we stand now?
    A John Camm
    St George s Hospital Medical School, London, United Kingdom
    Heart Rhythm 1:244-6. 2004
  5. ncbi request reprint Translation of clinical trials into clinical practice: use of results in formulating guidelines
    A John Camm
    Department of Cardiological Sciences, St George s Hospital Medical School, London, United Kingdom
    J Cardiovasc Electrophysiol 14:S9-14. 2003
  6. ncbi request reprint Clinical trial design to evaluate the effects of drugs on cardiac repolarization: current state of the art
    A John Camm
    St George s Hospital Medical School, University of London, Cranmer Terrace, London SW17 0RE, UK
    Heart Rhythm 2:S23-9. 2005
  7. ncbi request reprint What should we expect from the next generation of antiarrhythmic drugs?
    A J Camm
    Department of Cardiological Sciences, St George s Hospital Medical School, London, United Kingdom
    J Cardiovasc Electrophysiol 10:307-17. 1999
  8. ncbi request reprint Mortality in patients after a recent myocardial infarction: a randomized, placebo-controlled trial of azimilide using heart rate variability for risk stratification
    A John Camm
    Department of Cardiology, St George s Hospital, London, UK
    Circulation 109:990-6. 2004
  9. ncbi request reprint Electrophysiological effects of a single intravenous administration of ivabradine (S 16257) in adult patients with normal baseline electrophysiology
    A John Camm
    The Medical School, St George s Hospital, London, UK
    Drugs R D 4:83-9. 2003
  10. ncbi request reprint Rationale and patient selection for "hybrid" drug and device therapy in atrial and ventricular arrhythmias
    A John Camm
    Department of Cardiological Sciences, St George s Hospital Medical School, Cranmer Terrace, London SW17 0RE, UK
    J Interv Card Electrophysiol 9:207-14. 2003

Detail Information

Publications119 found, 100 shown here

  1. ncbi request reprint 5-hydroxytryptamine and atrial fibrillation: how significant is this piece in the puzzle?
    Shamil Yusuf
    Department of Cardiovascular Medicine, St Georges Hospital Medical School, London, United Kingdom
    J Cardiovasc Electrophysiol 14:209-14. 2003
    ..It also delves into the potential benefits and limitations of 5-HT4 antagonists in the prevention and management of this arrhythmia...
  2. ncbi request reprint Turbulence slope after atrial premature complexes is an independent predictor of mortality in survivors of acute myocardial infarction
    Dan Wichterle
    Department of Cardiac and Vascular Sciences, St George s Hospital Medical School, London, United Kingdom
    J Cardiovasc Electrophysiol 15:1350-6. 2004
    ..Atrial" turbulence slope (TSA) moderately correlates with "ventricular" turbulence slope (TSV). This study investigated the value of TSA assessed in 24-hour Holter recordings for postinfarction risk stratification...
  3. ncbi request reprint Rate versus rhythm control: is the debate over?
    A John Camm
    Department of Cardiological Sciences, St George s Hospital Medical School, London, UK
    J Interv Card Electrophysiol 7:7-11. 2002
  4. ncbi request reprint Advances in antiarrhythmic drug treatment of atrial fibrillation: where do we stand now?
    A John Camm
    St George s Hospital Medical School, London, United Kingdom
    Heart Rhythm 1:244-6. 2004
  5. ncbi request reprint Translation of clinical trials into clinical practice: use of results in formulating guidelines
    A John Camm
    Department of Cardiological Sciences, St George s Hospital Medical School, London, United Kingdom
    J Cardiovasc Electrophysiol 14:S9-14. 2003
    ..Arrhythmology guidelines now must be funded, implemented, value tested, and regularly revised...
  6. ncbi request reprint Clinical trial design to evaluate the effects of drugs on cardiac repolarization: current state of the art
    A John Camm
    St George s Hospital Medical School, University of London, Cranmer Terrace, London SW17 0RE, UK
    Heart Rhythm 2:S23-9. 2005
    ....
  7. ncbi request reprint What should we expect from the next generation of antiarrhythmic drugs?
    A J Camm
    Department of Cardiological Sciences, St George s Hospital Medical School, London, United Kingdom
    J Cardiovasc Electrophysiol 10:307-17. 1999
    ..Long-term goals of antiarrhythmic therapy include upstream approaches, such as identification of the biochemical intermediaries of the process and, eventually, of molecular and genetic lesions involved in arrhythmogenesis...
  8. ncbi request reprint Mortality in patients after a recent myocardial infarction: a randomized, placebo-controlled trial of azimilide using heart rate variability for risk stratification
    A John Camm
    Department of Cardiology, St George s Hospital, London, UK
    Circulation 109:990-6. 2004
    ..Azimilide, a novel class III antiarrhythmic drug, was investigated for its effects on mortality in patients with depressed LVF after recent MI and in a subpopulation of patients with low HRV...
  9. ncbi request reprint Electrophysiological effects of a single intravenous administration of ivabradine (S 16257) in adult patients with normal baseline electrophysiology
    A John Camm
    The Medical School, St George s Hospital, London, UK
    Drugs R D 4:83-9. 2003
    ..The safety profile of ivabradine was also investigated...
  10. ncbi request reprint Rationale and patient selection for "hybrid" drug and device therapy in atrial and ventricular arrhythmias
    A John Camm
    Department of Cardiological Sciences, St George s Hospital Medical School, Cranmer Terrace, London SW17 0RE, UK
    J Interv Card Electrophysiol 9:207-14. 2003
    ..Despite the lack of formal studies there is a very substantial clinical experience which testifies to the value of hybrid therapy for the management of both atrial fibrillation and ventricular tachycardia/fibrillation...
  11. ncbi request reprint The design and conduct of human studies to detect and quantify QT interval prolongation induced by new chemical entities
    A John Camm
    Department of Cardiological Sciences, St George s Hospital Medical School, London, UK
    Fundam Clin Pharmacol 16:141-5. 2002
  12. pmc Distribution of fast heart rate episodes during paroxysmal atrial fibrillation
    K Hnatkova
    Department of Cardiological Sciences, St George s Hospital Medical School, London, UK
    Heart 79:497-501. 1998
    ....
  13. ncbi request reprint QT dispersion does not represent electrocardiographic interlead heterogeneity of ventricular repolarization
    M Malik
    Department of Cardiological Sciences, St George s Hospital Medical School, London, United Kingdom
    J Cardiovasc Electrophysiol 11:835-43. 2000
    ..However, QTd may be largely due to projections of the repolarization dipole rather than "nondipolar" signals...
  14. ncbi request reprint Reflex autonomic modulation of automatically measured repolarization parameters
    A Ghuran
    Department of Cardiological Sciences, St George s Hospital Medical School, Cranmer Terrace, London SW17 0RE, UK
    Pacing Clin Electrophysiol 23:1973-6. 2000
    ..Newer concepts evaluating spatial and temporal irregularity of ventricular repolarization are still needed to reliably detect the effects of autonomic activity on ventricular repolarization...
  15. ncbi request reprint Depressed heart rate variability identifies postinfarction patients who might benefit from prophylactic treatment with amiodarone: a substudy of EMIAT (The European Myocardial Infarct Amiodarone Trial)
    M Malik
    Department of Cardiological Sciences, St George s Hospital Medical School, London, United Kingdom
    J Am Coll Cardiol 35:1263-75. 2000
    ..This substudy tested a prospective hypothesis that European Myocardial Infarct Amiodarone Trial (EMIAT) patients with depressed heart rate variability (HRV) benefit from amiodarone treatment...
  16. ncbi request reprint Mid- and long-term similarity of ventricular response to paroxysmal atrial fibrillation: digoxin versus placebo
    K Hnatkova
    Department of Cardiological Sciences, St George s Hospital Medical School, London, England
    Pacing Clin Electrophysiol 21:1735-40. 1998
    ..Thus in patients with paroxysmal AF, digoxin leads to more reproducible patterns of ventricular cycles that may be better tolerated clinically...
  17. ncbi request reprint Prevalent low-frequency oscillation of heart rate: novel predictor of mortality after myocardial infarction
    Dan Wichterle
    Department of Cardiological Sciences, St George s Hospital Medical School, London, UK
    Circulation 110:1183-90. 2004
    ..This study evaluates a novel method for postinfarction risk stratification based on frequency-domain characteristics of heart rate variability (HRV) in 24-hour Holter recordings...
  18. ncbi request reprint Comparison between biventricular pacing and single site pacing in patients with poor ventricular function: a hemodynamic study
    C Varma
    Dept of Cardiological Sciences, St George s Hospital Medical School, Cranmer Terrace, London SW17 ORE, UK
    Pacing Clin Electrophysiol 26:551-8. 2003
    ..There is individual variation in the pacing site that leads to the greatest improvement. In the group as a whole, biventricular and LV pacing produced only modest improvements compared to RV pacing...
  19. ncbi request reprint A prospective study of the efficacy and safety of adjuvant metoprolol and xamoterol in combination with amiodarone for resistant ventricular tachycardia associated with impaired left ventricular function
    Y Bashir
    Department of Cardiological Sciences, St George s Hospital Medical School, London, England
    Am Heart J 124:1233-40. 1992
    ..During a mean follow-up period of 13 months (range, 2 to 24 months), there were three cases of recurrent VT (in all patients VT remained inducible) and no sudden deaths.(ABSTRACT TRUNCATED AT 250 WORDS)..
  20. ncbi request reprint Adjuvant xamoterol or metoprolol in patients with malignant ventricular arrhythmia resistant to amiodarone
    V Paul
    Department of Cardiological Sciences, St George s Hospital Medical School, London
    Lancet 2:302-5. 1989
    ..Exercise tolerance was significantly greater during treatment with xamoterol/amiodarone than during treatment with metoprolol/amiodarone or with amiodarone alone...
  21. ncbi request reprint Short-, mid-, and long-term reproducibility of the atrial signal-averaged electrocardiogram in healthy subjects: comparison with the conventional ventricular signal-averaged electrocardiogram
    I Savelieva
    Department of Cardiological Sciences, St George s Hospital Medical School, London, United Kingdom
    Pacing Clin Electrophysiol 23:122-7. 2000
    ..The study showed a satisfactory short- and long-term reproducibility of Ptot in the atrial SAECG in healthy subjects. However, low reproducibility of the voltage parameters should be considered in clinical applications...
  22. ncbi request reprint New descriptors of homogeneity of the propagation of ventricular repolarization
    V Batchvarov
    Department of Cardiological Sciences, St George s Hospital Medical School, Cranmer Terrace, London SW17 0RE, England
    Pacing Clin Electrophysiol 23:1968-72. 2000
    ..These new temporal and wavefront direction descriptors are sensitive and rapid detectors of autonomic effects on ventricular repolarization...
  23. pmc Symptomatic improvement after radiofrequency catheter ablation for typical atrial flutter
    P A O'Callaghan
    Department of Cardiological Sciences, St George s Hospital Medical School, Cranmer Terrace, London SW17 0RE, UK
    Heart 86:167-71. 2001
    ..To assess the changes in quality of life, arrhythmia symptoms, and hospital resource utilisation following catheter ablation of typical atrial flutter...
  24. pmc Optimising the dichotomy limit for left ventricular ejection fraction in selecting patients for defibrillator therapy after myocardial infarction
    Yee Guan Yap
    Department of Cardiological Sciences, St George s Hospital Medical School, London, UK
    Heart 93:832-6. 2007
    ..The selection of patients for prophylactic implantable cardioverter-defibrilator (ICD) treatment after myocardial infarction (MI) remains controversial...
  25. ncbi request reprint Conventional and dedicated atrial overdrive pacing for the prevention of paroxysmal atrial fibrillation: the AFTherapy study
    A J Camm
    St George s Hospital, London, UK
    Europace 9:1110-8. 2007
    ....
  26. ncbi request reprint Risk assessment and prevention of sudden cardiac death in hypertrophic cardiomyopathy
    A K Slade
    Department of Cardiological Sciences, St George's Hospital Medical School, London, UK
    Arch Mal Coeur Vaiss 89:37-49. 1996
    ..Current therapeutic strategies are discussed including the role of drugs, the implantable cardioverter defibrillator, surgery and dual chamber pacing...
  27. ncbi request reprint Assessment of arrhythmias after myocardial infarction in the post-CAST era
    A J Camm
    Department of Cardiological Sciences, St George s Hospital Medical School, London, United Kingdom
    Can J Cardiol 12:9B-19B; discussion 27B-28B. 1996
    ..This article will review both the established and the new methods of risk stratification for the post MI patient, with particular attention to antiarrhythmic therapy...
  28. ncbi request reprint Ischaemic heart disease presenting as arrhythmias
    A V Ghuran
    Department of Cardiological Sciences, St George's Hospital Medical School, London, UK
    Br Med Bull 59:193-210. 2001
    ....
  29. ncbi request reprint Prognostic impact of demographic factors and clinical features on the mode of death in high-risk patients after myocardial infarction--a combined analysis from multicenter trials
    Yee Guan Yap
    Department of Cardiological Sciences, St George s Hospital Medical School, London, UK
    Clin Cardiol 28:471-8. 2005
    ..Contemporary information is lacking on the effect of demographic features and clinical features on the specific mode of mortality after myocardial infarction (MI) in the thrombolytic era...
  30. ncbi request reprint Heart rate turbulence-based predictors of fatal and nonfatal cardiac arrest (The Autonomic Tone and Reflexes After Myocardial Infarction substudy)
    Azad Ghuran
    Department of Cardiological and Public Health Sciences, St George s Hospital Medical School, London, United Kingdom
    Am J Cardiol 89:184-90. 2002
    ..By combining HR turbulence, BRS, and SDNN, a comprehensive assessment of cardiac autonomic reflexes and modulation can be obtained...
  31. ncbi request reprint Effect of amiodarone on the descending limb of the T wave
    Peter Smetana
    Department of Cardiological Sciences, St George s Hospital Medical School, Cranmer Terrace, London SW17 0RE, UK
    Am J Cardiol 92:742-6. 2003
    ..This contradicts the finding of decreased transmural repolarization heterogeneity by amiodarone and the appreciated antiarrhythmic efficacy of this drug...
  32. doi request reprint Atrial fibrillation: the rate versus rhythm management controversy
    A J Camm
    Division of Clinical Sciences, St George s University of London, Cranmer Terrace, London SW17 0RE, UK
    J R Coll Physicians Edinb 42:23-34. 2012
    ..In the meantime the pendulum of clinical opinion has begun to swing towards a rhythm control strategy...
  33. pmc Rate control in the medical management of atrial fibrillation
    A J Camm
    Division of Cardiac and Vascular Sciences, St George s University of London, London, UK
    Heart 93:35-8. 2007
  34. ncbi request reprint Pacing for heart failure
    C Varma
    Department of Cardiological Sciences, St George s Hospital Medical School, SW17 ORE, London, UK
    Lancet 357:1277-83. 2001
    ..Most recently, in addition to the conventional two leads used for pacing, a third lead to pace the left ventricle has been advocated in some patients with heart failure. We review the evidence for pacing in heart failure...
  35. pmc Comparative electrophysiological effects of captopril or hydralazine combined with nitrate in patients with left ventricular dysfunction and inducible ventricular tachycardia
    Y Bashir
    Department of Cardiological Sciences, St George s Hospital Medical School, London, UK
    Br Heart J 67:355-60. 1992
    ....
  36. ncbi request reprint Increased QT dispersion in patients with Prinzmetal's variant angina and cardiac arrest
    N Parchure
    Coronary Artery Disease Research Unit, Department of Cardiological Sciences, St George's Hospital Medical School, Cranmer Terrace, London SW17 0RE, UK
    Cardiovasc Res 50:379-85. 2001
    ..Increased QT dispersion may be both a substrate for sudden cardiac death and a marker of risk in patients with Prinzmetal's variant angina...
  37. ncbi request reprint Initial energy setting, outcome and efficiency in direct current cardioversion of atrial fibrillation and flutter
    M M Gallagher
    Department of Cardiological Sciences, St George s Hospital Medical School, London, United Kingdom
    J Am Coll Cardiol 38:1498-504. 2001
    ..The purpose of this study was to design a more efficient protocol for the electrical cardioversion of atrial arrhythmias...
  38. ncbi request reprint Is there an infective aetiology to atherosclerosis?
    S Gupta
    Department of Cardiological Sciences, St George s Hospital Medical School, London, England
    Drugs Aging 13:1-7. 1998
    ..A proven association could have important implications for public health worldwide, potentially leading to novel and relatively inexpensive therapeutic measures in the secondary prevention of CHD--broad-spectrum antibiotics...
  39. ncbi request reprint The use of drugs for cardioversion of recent onset atrial fibrillation and flutter. Focus on ibutilide
    O A Obel
    Department of Cardiological Sciences, St George s Hospital Medical School, London, England
    Drugs Aging 12:461-76. 1998
    ..Initial results are encouraging, particularly for atrial flutter. However, the drug has the potential for proarrhythmic effects and physicians who use it will need to be aware of these...
  40. ncbi request reprint Atrial pacing for the prevention and termination of atrial fibrillation
    Irina Savelieva
    St Georges Hospital Medical School, London SW17 0RE, United Kingdom
    Am J Geriatr Cardiol 11:380-98. 2002
    ..The evolution of hybrid therapy, in which two or more different strategies are employed in the same patient, may be the most effective approach to management of AF...
  41. ncbi request reprint Prognostic value of blood pressure measured during hospitalization after acute myocardial infarction: an insight from survival trials
    Yee Guan Yap
    Department of Cardiological Sciences, St George s Hospital Medical School, London, UK
    J Hypertens 25:307-13. 2007
    ..The prognostic value of blood pressure measured during hospitalization after acute myocardial infarction (MI) has not been investigated, particularly with regard to arrhythmic death...
  42. ncbi request reprint Novel If current inhibitor ivabradine: safety considerations
    Irina Savelieva
    St George s University of London, London, UK
    Adv Cardiol 43:79-96. 2006
    ..Ivabradine has been associated with a good safety profile during its clinical development and its safety will be further assessed by postmarketing surveillance and during on-going clinical trials...
  43. doi request reprint Ventricular pauses during atrial fibrillation predict relapse after electrical cardioversion: a prospective study
    Mark Michael Gallagher
    Division of Cardiac and Vascular Sciences, St George s Hospital, University of London, London, United Kingdom
    Pacing Clin Electrophysiol 33:934-8. 2010
    ..To investigate the use of ambulatory electrocardiogram (ECG) monitoring in atrial fibrillation (AF) to predict recurrence after electrical cardioversion (ECV)...
  44. pmc Effects of ventricular rate and regularity on the velocity and magnitude of left atrial appendage flow in atrial fibrillation
    O A Obel
    Department of Cardiological Sciences, St Georges Hospital Medical School, London, UK
    Heart 91:764-8. 2005
    ..To prospectively determine whether ventricular rate and regularity are significant determinants of the velocity and magnitude of left atrial appendage (LAA) flow...
  45. pmc Left atrial appendage: structure, function, and role in thromboembolism
    N M Al-Saady
    Cardiological Sciences, St George s Hospital Medical School, Cranmer Terrace, London SW17 0RE, UK
    Heart 82:547-54. 1999
    ....
  46. ncbi request reprint Evaluation of drug-induced QT interval prolongation: implications for drug approval and labelling
    M Malik
    Department of Cardiological Sciences, St George s Hospital Medical School, London, England
    Drug Saf 24:323-51. 2001
    ..The regulatory perspective includes careful adaptation of new research findings...
  47. ncbi request reprint The effects of adenosine on sinus node reentrant tachycardia
    M J Griffith
    Department of Cardiological Sciences, St Georges Hospital Medical School, London, England
    Clin Cardiol 12:409-11. 1989
    ....
  48. ncbi request reprint Deciphering the sinus tachycardias
    Shamil Yusuf
    Department of Cardiovascular Medicine, St Georges Hospital Medical School, London, UK
    Clin Cardiol 28:267-76. 2005
    ..Their definitions, clinical features, diagnostic criteria, pathophysiologic mechanisms, and optimum management are discussed in this review...
  49. doi request reprint Significance of QRS prolongation during diagnostic ajmaline test in patients with suspected Brugada syndrome
    Velislav N Batchvarov
    Division of Cardiac and Vascular Sciences, St George s University of London, London, England, United Kingdom
    Heart Rhythm 6:625-31. 2009
    ..Current consensus documents on Brugada syndrome recommend the diagnostic intravenous administration of a Na-channel blocker to be stopped when the QRS prolongs to > or =130% of baseline, presumably because of increased arrhythmic risk...
  50. ncbi request reprint Prognostic value of heterogeneity of ventricular repolarization in survivors of acute myocardial infarction
    Velislav N Batchvarov
    Department of Cardiac and Vascular Sciences, St George s Hospital Medical School, London, England
    Clin Cardiol 27:653-9. 2004
    ....
  51. ncbi request reprint Sample size, power calculations, and their implications for the cost of thorough studies of drug induced QT interval prolongation
    Marek Malik
    Section of Noninvasive Electrophysiology, Department of Cardiac and Vascular Sciences, St George s Hospital Medical School, London
    Pacing Clin Electrophysiol 27:1659-69. 2004
    ..g., three complexes in one lead only)...
  52. ncbi request reprint Association of Met439Thr substitution in heat shock protein 70 gene with postoperative atrial fibrillation and serum HSP70 protein levels
    Ali R Afzal
    Department of Clinical Developmental Sciences, St George s University of London, London, UK
    Cardiology 110:45-52. 2008
    ..Previously, we have shown that higher expression of heat shock protein (HSP) 70 was associated with decreased incidence of postoperative AF (PoAF), suggestive of an antiarrhythmic role...
  53. ncbi request reprint The sinus tachycardias
    Shamil Yusuf
    Department of Cardiovascular Medicine, St George s Hospital Medical School, London, UK
    Nat Clin Pract Cardiovasc Med 2:44-52. 2005
    ..Accurate diagnosis and appropriate therapy of the sinus tachycardias not only prevents multiple consultations but might also have important long-term prognostic implications...
  54. ncbi request reprint Arrhythmic complications of electrical cardioversion: relationship to shock energy
    Mark M Gallagher
    Department of Cardiological Sciences, St George s Hospital Medical School, Cranmer Terrace, London SW17 0RE, UK
    Int J Cardiol 123:307-12. 2008
    ..We hypothesised that more powerful shocks would exceed the upper limit of vulnerability for inducing ventricular fibrillation. The initial use of higher energy could therefore reduce arrhythmic complications...
  55. ncbi request reprint Quantification of mitochondrial sublimons in human fibrillating atria
    Nidal Maarouf
    Department of Cardiovascular Medicine, St George s Hospital Medical School, Cranmer Terrace, London SW17 0RE, UK
    Clin Sci (Lond) 106:653-9. 2004
    ..52), underlying disease ( P =0.94), medication and gender (2.84+/-0.72 in females vs 2.97+/-0.67 in males; P =0.431). In conclusion, our findings do not indicate any role of mtDNA in the pathophysiology of AF...
  56. ncbi request reprint Ventricular gradient and nondipolar repolarization components increase at higher heart rate
    Peter Smetana
    Department of Cardiological Sciences, St George s Hospital Medical School, Cranmer Terrace, London SW17 0RE, UK
    Am J Physiol Heart Circ Physiol 286:H131-6. 2004
    ..Whereas in women at all heart rates the sequence of repolarization more closely replicates the sequence of depolarization, localized repolarization is more heterogeneous than in men especially at fast heart rates...
  57. ncbi request reprint Prognostic significance of serial P wave signal-averaged electrocardiograms following external electrical cardioversion for persistent atrial fibrillation: a prospective study
    Xiao Hua Guo
    Department of Cardiological Sciences, St George s Hospital Medical School, Cranmer Terrace, London SW17 0RE, U K
    Pacing Clin Electrophysiol 26:299-304. 2003
    ..0028) and created a significant difference between the two slopes (P = 0.0004). The evolution of P-SAECG parameters after ECV differs in patients whose AF recurs versus patients who remain in SR...
  58. ncbi request reprint Ventricular gradient as a risk factor in survivors of acute myocardial infarction
    Velislav Batchvarov
    Department of Cardiological Sciences, St George s Hospital Medical School, Cranmer Terrace, London SW17 0RE, England
    Pacing Clin Electrophysiol 26:373-6. 2003
    ..Its predictive power did not differ significantly between the sexes. The role of TCRT as a risk-stratifier in post-MI patients deserves further prospective assessment in multivariate models with established risk factors...
  59. ncbi request reprint QT dispersion has no prognostic value in patients with symptomatic heart failure: an ELITE II substudy
    Yi Gang
    Department of Cardiological Sciences, St George s Hospital Medical School, Cranmer Terrace, London, SW17 0RE, United Kingdom
    Pacing Clin Electrophysiol 26:394-400. 2003
    ..In conclusion, increased QT dispersion is not associated with increased mortality in patients with heart failure, and is not suitable to examine drug efficacy in these patients...
  60. ncbi request reprint Heart rate turbulence after atrial and ventricular premature beats: relation to left ventricular function and coupling intervals
    Irina Savelieva
    Department of Cardiological Sciences, St George s Hospital Medical School, Cranmer Terrace, London, SW17 0RE, United Kingdom
    Pacing Clin Electrophysiol 26:401-5. 2003
    ..Heart rate turbulence (HRT) represents a biphasic chronotropic response of the sinus node to a single ventricular premature beat (VPB)...
  61. ncbi request reprint Paradoxical autonomic modulation of atrioventricular nodal conduction during heart rate turbulence
    Dan Wichterle
    Department of Cardiological Sciences, St George s Hospital Medical School, Cranmer Terrace, SW17 0RE London, United Kingdom
    Pacing Clin Electrophysiol 26:440-3. 2003
    ..Dynamics of AV delay has little impact on the accuracy of HRT assessment from surface ECG. The significant temporal dissociation of R-R and AV interval dynamics after a VPB remains unexplained...
  62. ncbi request reprint Comparison between ventricular gradient and a new descriptor of the wavefront direction of ventricular activation and recovery
    Velislav Batchvarov
    Department of Cardiological Sciences, St George s Hospital Medical School, London, UK
    Clin Cardiol 25:230-6. 2002
    ..Total R T cosine (TCRT) is a new descriptor of repolarization heterogeneity that quantifies the deviation between the directions of ventricular depolarization and repolarization. It revives the old concept of ventricular gradient (VG)...
  63. ncbi request reprint QT-RR relationship in healthy subjects exhibits substantial intersubject variability and high intrasubject stability
    Velislav N Batchvarov
    Department of Cardiological Sciences, St George s Hospital Medical School, London SW17 0RE, United Kingdom
    Am J Physiol Heart Circ Physiol 282:H2356-63. 2002
    ..This has practical implications for a precise estimation of the heart rate-corrected QT interval in which optimized subject-specific rate correction formulas should be used...
  64. ncbi request reprint The results of pacing trials for the prevention and termination of atrial tachyarrhythmias: is there any evidence of therapeutic breakthrough?
    Irina Savelieva
    Department of Cardiological Sciences, St George s Hospital Medical School, Cranmer Terrace, London SW1 0RE, United Kingdom
    J Interv Card Electrophysiol 8:103-15. 2003
    ..Dual chamber cardioverter-defibrillators with capacity to prevent and interrupt AF may offer more comprehensive and successful treatment for patients with advanced heart disease, frequent paroxysms of AF, and the risk of proarrhythmia...
  65. ncbi request reprint Sinus tachyarrhythmias and the specific bradycardic agents: a marriage made in heaven?
    Shamil Yusuf
    Department of Cardiovascular Medicine, St Georges Hospital Medical School, London, UK
    J Cardiovasc Pharmacol Ther 8:89-105. 2003
    ..The specific bradycardic agents, by the very nature of their mode of action, may prove ideal therapies for the management of the sinus tachyarrhythmias, and this is explored at every stage...
  66. doi request reprint Ivabradine for patients with stable coronary artery disease and left-ventricular systolic dysfunction (BEAUTIFUL): a randomised, double-blind, placebo-controlled trial
    Kim Fox
    Royal Brompton Hospital, London, UK
    Lancet 372:807-16. 2008
    ..We aimed to test whether lowering the heart rate with ivabradine reduces cardiovascular death and morbidity in patients with coronary artery disease and left-ventricular systolic dysfunction...
  67. ncbi request reprint Chlamydia pneumoniae, antimicrobial therapy and coronary heart disease: a critical overview
    S Gupta
    Department of Cardiological Sciences, St George s Hospital Medical School, London, UK
    Coron Artery Dis 9:339-43. 1998
    ..The results from large scale, prospective antibiotic trials in CHD, currently in progress, should help to clarify these important issues...
  68. ncbi request reprint Atrial fibrillation: is there a role for low-molecular-weight heparin?
    A J Camm
    Department of Cardiological Sciences, St George s Hospital Medical School, London, UK
    Clin Cardiol 24:I15-9. 2001
    ..Controlled clinical studies are still required, however, to establish a firm, evidence-based foundation for the use of LMWHs in AF...
  69. ncbi request reprint Programmed electrical stimulation, the signal-averaged electrocardiogram, and the implantable cardioverter-defibrillator in ventricular arrhythmias
    A J Camm
    St George s Hospital Medical School, London, UK
    Curr Opin Cardiol 7:55-64. 1992
    ..Furthermore, the cost of this form of therapy is very high and its prophylactic use has not been established...
  70. ncbi request reprint Double-blind placebo-controlled trial of digoxin in symptomatic paroxysmal atrial fibrillation
    F D Murgatroyd
    St George s Hospital Medical School, London, UK
    Circulation 99:2765-70. 1999
    ..Digoxin is commonly prescribed in symptomatic paroxysmal atrial fibrillation (AF) but has never been evaluated in this condition...
  71. ncbi request reprint Sex differences in repolarization homogeneity and its circadian pattern
    Peter Smetana
    Department of Cardiological Sciences, St George s Hospital Medical School, London SW17 0RE, United Kingdom
    Am J Physiol Heart Circ Physiol 282:H1889-97. 2002
    ..A sex difference was also observed for HR and QTc interval; however, the circadian patterns of the repolarization homogeneity descriptors were different from those of HR and QTc intervals...
  72. ncbi request reprint Potential cardiac toxicity of H1-antihistamines
    Yee Guan Yap
    St George s Hospital Medical School, London, England
    Clin Allergy Immunol 17:389-419. 2002
    ....
  73. ncbi request reprint Circadian rhythm of the corrected QT interval: impact of different heart rate correction models
    Peter Smetana
    Department of Cardiological Sciences, St George s Hospital Medical School, Cranmer Terrace, London SW17 0RE, England
    Pacing Clin Electrophysiol 26:383-6. 2003
    ....
  74. doi request reprint The place of hybrid therapies with drugs to supplement nonpharmacological therapies in atrial fibrillation
    Malini Govindan
    Division of Cardiac and Vascular Sciences, St Georges Hospital University of London, London, UK
    J Cardiovasc Pharmacol 52:210-21. 2008
    ..Despite this progress, no single modality confers benefit for all patients. Strategies to combine these treatment modalities in a hybrid approach has shown increasing promise for subgroups of AF patients...
  75. ncbi request reprint Treatment of atrial fibrillation
    Abhay Bajpai
    Ground Floor, Jenner Wing, St George s, University of London, Cranmer Terrace, Tooting, London SW170RE, UK
    Br Med Bull 88:75-94. 2008
    ..The presence of AF is associated with increased morbidity and mortality from stroke and heart failure, particularly in patients with structural heart disease...
  76. pmc Drug induced QT prolongation and torsades de pointes
    Yee Guan Yap
    Department of Cardiological Sciences, St George s Hospital Medical School, London, UK
    Heart 89:1363-72. 2003
  77. ncbi request reprint Delayed paced ventricular activation in the long QT syndrome is associated with ventricular fibrillation
    Richard C Saumarez
    Department of Cardiology, Papworth Hospital, Cambridge, United Kingdom
    Heart Rhythm 3:771-8. 2006
    ..LQTS may cause sudden cardiac death (SCD), but the mechanisms linking gene mutations to ventricular fibrillation (VF) are unclear...
  78. pmc Relation between QT and RR intervals is highly individual among healthy subjects: implications for heart rate correction of the QT interval
    M Malik
    Department of Cardiological Sciences, St George s Hospital Medical School, Cranmer Terrace, London SW17 ORE, UK
    Heart 87:220-8. 2002
    ..To compare the QT/RR relation in healthy subjects in order to investigate the differences in optimum heart rate correction of the QT interval...
  79. pmc Effect of multisite pacing on ventricular coordination
    C Varma
    Department of Cardiological Sciences, St George s Hospital Medical School, Cranmer Terrace, London SW17 0RE, UK
    Heart 87:322-8. 2002
    ..To determine the effect of multisite pacing on left ventricular function...
  80. doi request reprint The unravelling of primary myocardial impairment in Marfan syndrome by modern echocardiography
    A Kiotsekoglou
    Department of Cardiac and Vascular Sciences, St George s, University of London, Cranmer Terrace, London SW17 0RE, UK
    Heart 95:1561-6. 2009
    ..Biventricular function assessment should be added to the aortic root evaluation, so that appropriate treatment may be offered to support myocardial function...
  81. ncbi request reprint Impact of electrocardiogram recording format on QT interval measurement and QT dispersion assessment
    T S Faber
    Department of Cardiological Sciences, St. George's Hospital Medical School, London, United Kingdom
    Pacing Clin Electrophysiol 24:1739-47. 2001
    ..Thus, QT dispersion appears to reflect merely the presence of more complex repolarization patterns in patients at risk of arrhythmias...
  82. ncbi request reprint I f inhibition with ivabradine : electrophysiological effects and safety
    Irina Savelieva
    Division of Cardiac and Vascular Sciences, St George s University of London, Cranmer Terrace, London, UK
    Drug Saf 31:95-107. 2008
    ..The safety of ivabradine will be further assessed by postmarketing surveillance and during on-going clinical trials...
  83. doi request reprint Safety considerations in the pharmacological management of atrial fibrillation
    A John Camm
    Department of Cardiological Sciences, St George s University of London, Cranmer Terrace, London SW17 0RE, United Kingdom
    Int J Cardiol 127:299-306. 2008
    ..Notwithstanding these considerations, most patients with AF can be considered for rhythm control, provided there is adequate pre-treatment assessment and protocols for initiation, dosing and monitoring are followed with care...
  84. doi request reprint Prolongation of the QT interval and ventricular arrhythmias: some early observations
    Velislav N Batchvarov
    Division of Cardiac and Vascular Sciences, St George s University of London, London, United Kingdom
    Heart Rhythm 5:892-4. 2008
  85. ncbi request reprint Stroke in atrial fibrillation: update on pathophysiology, new antithrombotic therapies, and evolution of procedures and devices
    Irina Savelieva
    St George s University of London, London, United Kingdom
    Ann Med 39:371-91. 2007
    ....
  86. ncbi request reprint Association of high intracellular, but not serum, heat shock protein 70 with postoperative atrial fibrillation
    Kaushik Mandal
    Department of Cardiothoracic Surgery, St George s Hospital and Medical School, London, United Kingdom
    Ann Thorac Surg 79:865-71; discussion 871. 2005
    ..We therefore set out to examine the influence of heat shock protein 70 on the incidence of postoperative atrial fibrillation...
  87. ncbi request reprint Effect of treatment for Chlamydia pneumoniae and Helicobacter pylori on markers of inflammation and cardiac events in patients with acute coronary syndromes: South Thames Trial of Antibiotics in Myocardial Infarction and Unstable Angina (STAMINA)
    Adam F M Stone
    Department of Gastroenterology, St George s Hospital Medical School, Tooting, London, UK
    Circulation 106:1219-23. 2002
    ..We conducted an intervention study using antibiotics against these bacteria in patients with acute coronary syndromes to determine whether antibiotics reduce inflammatory markers and adverse cardiac events...
  88. ncbi request reprint Significance of maximal and regional left ventricular wall thickness in association with arrhythmic events in patients with hypertrophic cardiomyopathy
    Valentina O Puntmann
    St George s, University of London, Cranmer Terrace, UK
    Circ J 74:531-7. 2010
    ..Patients with mild left ventricular hypertrophy (LVH) are not free of events. Regional heterogeneity of LVH may contribute to arrhythmic vulnerability...
  89. ncbi request reprint Embolic complications of direct current cardioversion of atrial arrhythmias: association with low intensity of anticoagulation at the time of cardioversion
    Mark M Gallagher
    Department of Cardiological Sciences, St George s Hospital Medical School, London, United Kingdom
    J Am Coll Cardiol 40:926-33. 2002
    ..The goal of this study was to identify the factors responsible for embolic complications of direct current (DC) cardioversion of atrial arrhythmias...
  90. ncbi request reprint Atrial fibrillation in the elderly--a near epidemic
    A John Camm
    Department of Clinical Cardiology, St Georges Hospital Medical School, London, United Kingdom
    Am J Geriatr Cardiol 11:352. 2002
  91. doi request reprint Combined metabolomic and proteomic analysis of human atrial fibrillation
    Manuel Mayr
    Cardiovascular Division, King s College, London, United Kingdom
    J Am Coll Cardiol 51:585-94. 2008
    ..We sought to decipher metabolic processes servicing the increased energy demand during persistent atrial fibrillation (AF) and to ascertain whether metabolic derangements might instigate this arrhythmia...
  92. doi request reprint Diagnostic utility of bipolar precordial leads during ajmaline testing for suspected Brugada syndrome
    Velislav N Batchvarov
    St George s University of London, London, UK
    Heart Rhythm 7:208-15. 2010
    ..Leads V(1) and V(2) recorded from the standard position (fourth intercostal space) have insufficient sensitivity to detect the diagnostic type 1 Brugada ECG pattern...
  93. ncbi request reprint Post-extrasystolic changes of the T wave in a patient with congestive heart failure
    Velislav N Batchvarov
    Division of Cardiac and Vascular Sciences, St George s University of London, Cranmer Terrace, London SW17 0RE, UK
    Europace 9:1093. 2007
  94. doi request reprint New antiarrhythmic drugs for atrial fibrillation: focus on dronedarone and vernakalant
    A John Camm
    Division of Cardiac and Vascular Sciences, St George s University of London, Cranmer Terrace, London, SW17 0RE, UK
    J Interv Card Electrophysiol 23:7-14. 2008
    ....
  95. ncbi request reprint Potential demographic and baselines variables for risk stratification of high-risk post-myocardial infarction patients in the era of implantable cardioverter-defibrillator--a prognostic indicator
    Yee Guan Yap
    Department of Cardiological Sciences, St George s Hospital Medical School, London, United Kingdom
    Int J Cardiol 126:101-7. 2008
    ..Risk stratification after myocardial infarction (MI) remains expensive and disappointing. We designed a prognostic indicator using demographic information to select patients at risk of dying after MI...
  96. pmc Some patients with paroxysmal atrial fibrillation should carry flecainide or propafenone to self treat
    A John Camm
    St George s, University of London, London SW17 0RE
    BMJ 334:637. 2007
  97. ncbi request reprint Brugada-like changes in the peripheral leads during diagnostic ajmaline test in patients with suspected Brugada syndrome
    Velislav N Batchvarov
    Division of Cardiac and Vascular Sciences, St George s University of London, London, UK
    Pacing Clin Electrophysiol 32:695-703. 2009
    ..Although cases of Brugada-type electrocardiographic (ECG) pattern in peripheral (limb) leads have been reported ("atypical" Brugada syndrome [BS]), their incidence in patients investigated for BS is unknown...
  98. ncbi request reprint Atrial fibrillation and the urologist
    Khurshid R Ghani
    Department of Urology, St George s Hospital, London, UK
    BJU Int 94:254-5. 2004
  99. doi request reprint Postextrasystolic changes in the complexity of the QRS complex and T wave
    Velislav N Batchvarov
    The Division of Cardiac and Vascular Sciences, St George s University of London, Cranmer Terrace, London, United Kingdom
    Ann Noninvasive Electrocardiol 13:421-5. 2008
    ..In both subjects, T-wave complexity of the first post-VPB beat was significantly increased compared to the beats preceding the VPB...
  100. ncbi request reprint Rhythm control versus rate control for atrial fibrillation and heart failure
    Denis Roy
    Montreal Heart Institute and the Université de Montréal, Montreal, QC H1T 1C8, Canada
    N Engl J Med 358:2667-77. 2008
    ..However, the benefits and risks of this approach have not been adequately studied...
  101. ncbi request reprint The efficacy of azimilide in the treatment of atrial fibrillation in the presence of left ventricular systolic dysfunction: results from the Azimilide Postinfarct Survival Evaluation (ALIVE) trial
    Craig M Pratt
    The Methodist DeBakey Heart Center and Department of Medicine, Section of Cardiology, Baylor College of Medicine, Houston, Texas 77030, USA
    J Am Coll Cardiol 43:1211-6. 2004
    ....