M M Gompels

Summary

Affiliation: Southmead Hospital
Country: UK

Publications

  1. doi request reprint Does discordancy between the CD4 count and CD4 percentage in HIV-positive individuals influence outcomes on highly active antiretroviral therapy?
    Mark Gompels
    North Bristol NHS Trust, Bristol, United Kingdom
    J Infect Dis 205:540-7. 2012
  2. pmc HAE international home therapy consensus document
    Hilary J Longhurst
    Department of Immunology, Barts and The London NHS Trust, London, UK
    Allergy Asthma Clin Immunol 6:22. 2010
  3. doi request reprint Cinryze (C1-inhibitor) for the treatment of hereditary angioedema
    Mark M Gompels
    Immunology and Immunogenetics, Pathology Sciences, North Bristol NHS Trust, Southmead Hospital, Bristol, BS10 5NB, UK
    Expert Rev Clin Immunol 7:569-73. 2011
  4. ncbi request reprint Laboratory testing for C1 inhibitor deficiency: a comparison of two approaches to C1 inhibitor function
    M M Gompels
    Immunology and Immunogenetics, North Bristol NHS Trust, Southmead Hospital, Bristol BS10 5NB, UK
    Ann Clin Biochem 44:75-8. 2007
  5. pmc C1 inhibitor deficiency: consensus document
    M M Gompels
    Department of Immunology and Immunogenetics, North Bristol NHS Trust, Southmead Hospital, Bristol, UK
    Clin Exp Immunol 139:379-94. 2005
  6. pmc Echocardiographic abnormalities in primary antibody deficiency
    S L Johnston
    Department of Immunology and Immunogenetics, Southmead Hospital, Bristol, UK
    Postgrad Med J 80:214-8. 2004
  7. ncbi request reprint Misdiagnosis of hereditary angio-oedema type 1 and type 2
    M M Gompels
    Department of Immunology and Immunogenetics, Southmead Hospital, Westbury on Trym, Bristol, BS10 5NB, UK
    Br J Dermatol 148:719-23. 2003
  8. ncbi request reprint C1-inhibitor deficiencies (hereditary angioedema): where are we with therapies?
    R J Lock
    Immunology and Immunogenetics, North Bristol NHS Trust, Southmead Hospital, Westbury on Trym, Bristol, BS10 5NB, UK
    Curr Allergy Asthma Rep 7:264-9. 2007
  9. pmc Lymphoproliferative disease in antibody deficiency: a multi-centre study
    M M Gompels
    Immunology and Immunogenetics, Southmead Hospital, North Bristol NHS Trust, Bristol, UK
    Clin Exp Immunol 134:314-20. 2003
  10. ncbi request reprint C1 inhibitor deficiency: management
    M M Gompels
    Department of Immunology and Immunogenetics, Southmead Hospital, Bristol, UK
    Clin Exp Dermatol 30:737-40. 2005

Detail Information

Publications16

  1. doi request reprint Does discordancy between the CD4 count and CD4 percentage in HIV-positive individuals influence outcomes on highly active antiretroviral therapy?
    Mark Gompels
    North Bristol NHS Trust, Bristol, United Kingdom
    J Infect Dis 205:540-7. 2012
    ..Although individuals may show discordancy between their CD4 count and CD4%, the clinical relevance of this is unclear...
  2. pmc HAE international home therapy consensus document
    Hilary J Longhurst
    Department of Immunology, Barts and The London NHS Trust, London, UK
    Allergy Asthma Clin Immunol 6:22. 2010
    ..It represents the opinion of the authors who have a wide range of expert experience in the management of HAE...
  3. doi request reprint Cinryze (C1-inhibitor) for the treatment of hereditary angioedema
    Mark M Gompels
    Immunology and Immunogenetics, Pathology Sciences, North Bristol NHS Trust, Southmead Hospital, Bristol, BS10 5NB, UK
    Expert Rev Clin Immunol 7:569-73. 2011
    ..Cinryze and other similar products are going to change the future management of hereditary angioedema and have potential in other areas of medicine...
  4. ncbi request reprint Laboratory testing for C1 inhibitor deficiency: a comparison of two approaches to C1 inhibitor function
    M M Gompels
    Immunology and Immunogenetics, North Bristol NHS Trust, Southmead Hospital, Bristol BS10 5NB, UK
    Ann Clin Biochem 44:75-8. 2007
    ..Two different methods are commercially available to measure C1 inhibitor function. There are few data comparing these assays...
  5. pmc C1 inhibitor deficiency: consensus document
    M M Gompels
    Department of Immunology and Immunogenetics, North Bristol NHS Trust, Southmead Hospital, Bristol, UK
    Clin Exp Immunol 139:379-94. 2005
    ..Individual sections provide special advice with respect to diagnosis, management (prophylaxis and emergency care), special situations (childhood, pregnancy, contraception, travel and dental care) and service specification...
  6. pmc Echocardiographic abnormalities in primary antibody deficiency
    S L Johnston
    Department of Immunology and Immunogenetics, Southmead Hospital, Bristol, UK
    Postgrad Med J 80:214-8. 2004
    ..To document cardiac abnormalities secondary to pulmonary disease in primary antibody deficiency...
  7. ncbi request reprint Misdiagnosis of hereditary angio-oedema type 1 and type 2
    M M Gompels
    Department of Immunology and Immunogenetics, Southmead Hospital, Westbury on Trym, Bristol, BS10 5NB, UK
    Br J Dermatol 148:719-23. 2003
    ..Serological assays to measure C1 inhibitor concentration and function are widely available. However, expert interpretation may not be...
  8. ncbi request reprint C1-inhibitor deficiencies (hereditary angioedema): where are we with therapies?
    R J Lock
    Immunology and Immunogenetics, North Bristol NHS Trust, Southmead Hospital, Westbury on Trym, Bristol, BS10 5NB, UK
    Curr Allergy Asthma Rep 7:264-9. 2007
    ..Some agents are likely to have a wider role in treatment of other, more common, forms of angioedema...
  9. pmc Lymphoproliferative disease in antibody deficiency: a multi-centre study
    M M Gompels
    Immunology and Immunogenetics, Southmead Hospital, North Bristol NHS Trust, Bristol, UK
    Clin Exp Immunol 134:314-20. 2003
    ..Isolated evidence of clonality in biopsy material is therefore an insufficient diagnostic criterion to determine malignancy. Furthermore, our data suggest that clonal expansions are rarely the result of Epstein-Barr virus-driven disease...
  10. ncbi request reprint C1 inhibitor deficiency: management
    M M Gompels
    Department of Immunology and Immunogenetics, Southmead Hospital, Bristol, UK
    Clin Exp Dermatol 30:737-40. 2005
    ..This summary focuses on the management of the disorder including prophylaxis, emergency treatment and special situations such as pregnancy and dental care...
  11. ncbi request reprint C1 inhibitor deficiency: diagnosis
    M M Gompels
    Southmead Hospital, Bristol, UK
    Clin Exp Dermatol 30:460-2. 2005
    ..This is the first of two articles on C1 inhibitor deficiency based on a recent UK consensus document covering diagnosis and management of the disorder in both adults and children. This paper focuses on diagnosis of this disorder...
  12. ncbi request reprint Subclinical hypothyroidism: a comparison of strategies to achieve adherence to treatment guidelines
    R J Lock
    Immunology and Immunogenetics, North Bristol NHS Trust, Southmead Hospital, Bristol BS10 5NB, UK
    Ann Clin Biochem 41:197-200. 2004
    ..Patients with subclinical hypothyroidism who also have anti-thyroid peroxidase (TPO) antibodies have a higher conversion to overt hypothyroidism than those without, and treatment with thyroxine is recommended...
  13. pmc Scedosporium apiospermum in chronic granulomatous disease treated with an HLA matched bone marrow transplant
    M M Gompels
    Department of Immunology, Southmead Hospital, Bristol, BS10 5NB, UK Department of Immunology, Royal Victoria Infirmary, Newcastle upon Tyne NE1 4LP, UK
    J Clin Pathol 55:784-6. 2002
    ..Treatment required an HLA matched bone marrow transplant, which led to complete clearance of the fungal infection, although the patient subsequently died...
  14. pmc Proposed use of adrenaline (epinephrine) in anaphylaxis and related conditions: a study of senior house officers starting accident and emergency posts
    L L Gompels
    Department of Medicine, North Avon NHS Trust, Southmead Hospital, Westbury on Trym, Bristol
    Postgrad Med J 78:416-8. 2002
    ..This has implications for training as the survey took place before the start of the A&E posting. Anaphylaxis is over-diagnosed and poorly treated despite Resuscitation Council guidelines...
  15. pmc Takayasu arteritis: a review
    S L Johnston
    Department of Immunology and Immunogenetics, Southmead Hospital, Westbury on Trym, Bristol BS10 5NB, UK
    J Clin Pathol 55:481-6. 2002
    ..As with any rare disease, randomised controlled treatment trials are either lacking or based on small patient numbers, making management decisions difficult. Current evidence based treatments are presented and discussed...
  16. pmc A multicentre evaluation of the diagnostic efficiency of serological investigations for C1 inhibitor deficiency
    M M Gompels
    Immunology and Immunogenetics, Southmead Hospital, Bristol BS10 5NB, UK
    J Clin Pathol 55:145-7. 2002
    ..To determine the diagnostic efficiency of assays routinely used in the investigation of hereditary angio-oedema...