J D Simmons

Summary

Country: UK

Publications

  1. pmc Vitamin D receptor gene polymorphism: association with Crohn's disease susceptibility
    J D Simmons
    Gastroenterology Unit, University of Oxford, Radcliffe Infirmary, UK
    Gut 47:211-4. 2000
  2. pmc MHC class I chain-like gene A (MICA) and its associations with inflammatory bowel disease and peripheral arthropathy
    T R Orchard
    Gastroenterology Unit, University of Oxford, Radcliffe Infirmary, Oxford, UK
    Clin Exp Immunol 126:437-40. 2001

Collaborators

Detail Information

Publications2

  1. pmc Vitamin D receptor gene polymorphism: association with Crohn's disease susceptibility
    J D Simmons
    Gastroenterology Unit, University of Oxford, Radcliffe Infirmary, UK
    Gut 47:211-4. 2000
    ..It is the cellular receptor for 1,25(OH)(2) vitamin D(3) (calcitriol) which has a wide range of different regulatory effects on the immune system. IBD is characterised by activation of the mucosal immune system...
  2. pmc MHC class I chain-like gene A (MICA) and its associations with inflammatory bowel disease and peripheral arthropathy
    T R Orchard
    Gastroenterology Unit, University of Oxford, Radcliffe Infirmary, Oxford, UK
    Clin Exp Immunol 126:437-40. 2001
    ..0001). MICA*007 is associated with susceptibility to UC in our population and MICA*008 with type 2 IBD PeA. Further work is now required to assess the distribution and expression of MICA throughout the gut in health and disease...