- Vitamin D receptor gene polymorphism: association with Crohn's disease susceptibilityJ D Simmons
Gastroenterology Unit, University of Oxford, Radcliffe Infirmary, UK
Gut 47:211-4. 2000..It is the cellular receptor for 1,25(OH)(2) vitamin D(3) (calcitriol) which has a wide range of different regulatory effects on the immune system. IBD is characterised by activation of the mucosal immune system...
- MHC class I chain-like gene A (MICA) and its associations with inflammatory bowel disease and peripheral arthropathyT R Orchard
Gastroenterology Unit, University of Oxford, Radcliffe Infirmary, Oxford, UK
Clin Exp Immunol 126:437-40. 2001..0001). MICA*007 is associated with susceptibility to UC in our population and MICA*008 with type 2 IBD PeA. Further work is now required to assess the distribution and expression of MICA throughout the gut in health and disease...